📢 We’re excited to announce our presence at the ECV Congress 2025! 🗓 April 27–30, 2025 📍 Dubrovnik, Croatia Join us at our booth to explore InvivoGen’s latest innovations in: 🧬 Reporter cell lines 🧪 PRR ligands & cytokine bioassays 🐭 Mouse anti-mouse antibodies … and many more trusted reagents for immunology, virology & cell signalling research. 🥼 Let’s connect! 🤝 We’re looking forward to learning more about your work and discussing how InvivoGen can support your next discovery. #ScientificResearch #Biotechnology #Immunology #Virology #CellCulture #LabTech #ReporterCells #TLRs #Cytokines #BiotechEvents #InvivoGen
InvivoGen
Biotechnology Research
San Diego, California 7,960 followers
INNOVATION WITHIN REACH
About us
At InvivoGen, we strive to provide life scientists worldwide with innovative, high quality and reliable reagents. As specialists in cell culture engineering and innate immunity, we are passionate about designing, developing, and bringing to market new tools and services for cutting-edge research. At our three regional headquarters — in Toulouse (France), San Diego (USA) and Hong Kong (China) — and through our dedicated multilingual customer support staff, we can provide researchers around the globe with the reagents and product information that they need to make the scientific breakthroughs of tomorrow. InvivoGen is a privately held company founded by university researchers in 1977 in Toulouse, France. Since then, we have gradually expanded with the opening of InvivoGen San Diego, in 1997, and InvivoGen Hong Kong, in 2014. Our unparalleled skills in microbial fermentation enable us to produce a wide range of bioactive molecules, including ultra-pure antibiotics, novel mycoplasma treatments and the largest available collection of pattern recognition receptor agonists, from various micro-organisms. Over 25% of InvivoGen’s employees hold a PhD in biology or chemistry. Through specialized R&D teams, they work together seamlessly to design, produce and validate novel plasmids, cell lines, vaccine adjuvants and synthetic ligands for research in areas as diverse as gene therapy, molecular immunology and vaccination. Moreover, based on our first-hand knowledge of innate immune receptor signaling pathways, we have devised an ever-expanding collection of reporter cell lines, including cytokine reporter cells and knockout (KO) cell lines for high-priority innate immune targets. Scientists depend on InvivoGen for quality, consistency and reliability. Whatever research challenges you are facing, count on InvivoGen to provide you with the tools and solutions that you need.
- Website
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http://www.invivogen.com
External link for InvivoGen
- Industry
- Biotechnology Research
- Company size
- 51-200 employees
- Headquarters
- San Diego, California
- Type
- Privately Held
- Founded
- 1977
- Specialties
- Research Reagents, Innate Immunity, Gene Therapy, IgA, Fermentation, Monoclonal Antibodies, Molecular Biology, Vaccine Adjuvants, Cell Culture, Selective Antibiotics, TLR Ligands, PRR Ligands, Nucleic Acid Sensing, cGAS/STING, Interferon Pathways, LPS, and Transfection
Locations
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Primary
Get directions
10515 Vista Sorrento Pkwy
San Diego, California 92121, US
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Get directions
5 rue Jean Rodier
TOULOUSE, 31400, FR
Employees at InvivoGen
Updates
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A Simpler Way to Detect Cell Death! 🔍 Introducing LDH-Blue™ 🔵, InvivoGen’s powerful new colorimetric assay designed to detect cytotoxicity with precision and ease. Whether you're studying ferroptosis, pyroptosis, necroptosis, or immune-mediated cytotoxicity, this ready-to-use kit is built to give fast, reliable results, in under 30 minutes. 🥼 Why scientists already love it: ✅ Visual readout with clear blue color shift ✅ Precise & sensitive ✅ No interference with phenol red ✅ Absorbance linearity with the number of lysed cells ✅ Add/Mix/Read format = zero hassle ✅ Cost-effective and scalable 💡 Ideal for applications like ADCC, drug screening, and genetic perturbation studies. 🔗 LDH Blue™ Cytotoxicity Assay : https://lnkd.in/e7SY9H3M Curious to see how LDH-Blue™ compares to your current readout? 💬 Contact us & we’ll send you validation data and the full experimental protocol to get started! #CellCulture #Cytotoxicity #CellDeath #ScientificResearch #Biotechnology #Immunology #LabTech #DrugDiscovery #InvivoGen
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✨ Elevate Your Research with InvivoGen Antibodies! 🧪 Precision. Reliability. Innovation. Our cutting-edge antibodies are engineered for high specificity and consistent performance, giving researchers the confidence to push scientific boundaries. Whether you're identifying key pathways or exploring new discoveries, InvivoGen delivers results you can trust. 🚀 Explore the collection today: https://lnkd.in/e3ubjeby #MonoclonalAntibodies #Antibodies #Immunology #CancerResearch #VaccineDevelopment #InflammationResearch #ScientificResearch #Innovation #Biotechnology #LabTech #InvivoGen
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📢 New tools to unlock the secrets of ferroptosis, now available! Ferroptosis, a form of regulated cell death, is reshaping how we study oxidative stress, cancer, and immunogenicity. To support cutting-edge research, InvivoGen has launched a complete ferroptosis product range: 🧫 HT1080-HMGB1-Lucia™ Cells → Reporter cells designed to monitor ferroptosis via the release of HMGB1::Lucia, a sensitive & convenient alternative to traditional cytotoxicity assays. 🔥 RSL3, GPX4 Inhibitor → A potent ferroptosis inducer that directly targets GPX4, triggering ROS accumulation and membrane damage. 🛡 Ferrostatin-1, Ferroptosis Inhibitor → A synthetic antioxidant that blocks lipid ROS and protects cells from ferroptotic death. ✅ Reporter Cell Line: Each-lot is Functionally Validated & Mycoplasma free. ✅ Ligands: InvitroFit™ (≥95% purity), Endotoxin-free (tested with EndotoxDetect™) & Functionally Tested and Validated in cell-based assays. Whether you're investigating cell death, screening therapeutics, or exploring redox biology, this toolbox is built for you. 🛠 Links to these tools are available in the comments below. 👇 💬 Have any questions about these products? Contact us! Our technical support team will be happy to assist you. #Ferroptosis #CellDeath #Immunology #Biotechnology #OxidativeStress #CellCulture #ScientificResearch #DrugDiscovery #CancerResearch #LabTech #InvivoGen
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Cracking the Code of RNA Sensing! 🧬 When a virus enters the body, the immune system’s first responders, dsRNA sensors, go into action! But how do we study their precise roles? That’s where InvivoGen’s HEK-Dual™ RNA Sensor Cell Lines come in. 🚀 🔬 Designed to study TLR3, RIG-I, and MDA5 signaling, these engineered cell lines provide: ✅ Selective RNA Sensor Activation – Study each PRR in isolation! ✅ Dual Reporter System – Monitor NF-κB & IRF pathways simultaneously. ✅ Reproducible & Reliable – Stringently tested for stability & performance. ✅ Effortless Readout – Compatible with QUANTI-Blue™ & QUANTI-Luc™ for seamless detection. From mRNA vaccine development to antiviral drug discovery, these cell lines offer a powerful tool for researchers tackling RNA-mediated immunity. 💡 Are RNA sensors the key to unlocking the next breakthrough in immunotherapy? Let’s discuss! 💬👇 #RNAImmunity #TLR3 #RIGI #MDA5 #MolecularBiology #VaccineDevelopment #DrugDiscovery #InvivoGen #LabTech #Biotechnology #Immunology
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Can gut bacteria help the immune system fight cancer more effectively? A recent study in Nature Microbiology (10 February 2025) highlights this with an important nuance: the structure of bacterial molecules matters. The researchers show that hexaacylated LPS, especially from E. coli, can boost the effectiveness of PD-1 immune checkpoint inhibitors in mice. In contrast, underacylated LPS from Bacteroides had no such effect. To measure this, a combination of advanced tools, including THP1-Dual™ TLR4 reporter cell lines and ultrapure LPS standards from InvivoGen, were used to demonstrate how subtle structural differences in LPS can impact TLR4 activation and ultimately, tumor control. Swipe through the carousel for a summary of the findings. 💬 Check the comments for links to the full article and product references used. Could microbiome-based molecules become the next generation of immunotherapy adjuvants? We’d love to hear your thoughts. #CancerResearch #Immunotherapy #TLR4 #LPS #Microbiome #Biotechnology #InnateImmunity #Immunology #Research #InvivoGen
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🥼 Expand Your PRR Signaling Research with InvivoGen! We are happy to complement our PRR signaling Poster range with tools designed to support RLR, CLR, and CDS signaling research. Discover our catalog of cell lines, ligands, inhibitors, antibodies, and genes to study RIG-like receptors, C-type lectin receptors, and cytosolic DNA sensing signaling. As always, InvivoGens products are functionally tested and free of bacterial contaminants to simplify your research with reliable results. Take your research further with tools you can trust. 👉 Read more: https://lnkd.in/eYc3TUQK (RLR tools) https://lnkd.in/eGvibkn6 (CLR tools) https://lnkd.in/e264u3dp (CDS tools) 📥 Get your digital download here: https://lnkd.in/eDhiaaZb #InvivoGen #PRRSignaling #RLR #CLR #CDS #Immunology #Biotech #QualityReagents
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Meet Us at SPI Congress 2025! 🤝 📍 Lisbon, Portugal 🗓️ 9-11, April 2025 We're thrilled to announce that InvivoGen will be attending the SPI Congress 2025, an unmissable event for immunology and infectious disease research. As Specialists in immune response research tools, we’ll be showcasing: ✔️ Our complete range of PRR ligands & inhibitors ✔️ Highly specific Antibodies (Bispecific, Biosimilar etc.) ✔️ Functionally Tested Reporter Cell Lines, Guaranteed mycoplasma free ✔️ Highly Pure Selective Antibiotics ✔️ Antimicrobial reagents & detection kits Whether you're looking for reliable reagents or expert scientific support, our team will be there to answer your questions. 👉 Let’s connect! Stop by our booth to discuss your research projects and needs. #SPI2025 #Immunology #InnateImmunity #TLRs #ScientificResearch #Biotech #InvivoGen #Cytokines #Immunostimulants #CellCulture #Antibiotics #SPIcongress
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Skip PMA treatment and get reliable TLR4 activation with THP1-Dual™ MD2-CD14-TLR4 Cells! Are you struggling with PMA-induced background noise in TLR4 studies? When studying TLR4-induced IRF activation, PMA differentiation is often necessary for THP-1-derived cells due to their low expression of CD14, MD-2, and TLR4. ❌ However, PMA treatment can introduce unwanted variables: Background noise → Secreted SEAP remains in the medium for days Time-consuming protocols → Requires differentiation & medium changes Variability in results → Additional steps introduce inconsistencies 🛠 A Game-Changer for TLR4 Research Our THP1-Dual™ MD2-CD14-TLR4 cells overexpress MD-2, CD14, and TLR4, eliminating the need for PMA treatment. ✅ Directly study TLR4-dependent IRF activation ✅ Skip PMA differentiation & avoid background noise ✅ Gain faster, more reproducible results Discover how our optimized THP-1 models can improve your research 👇 https://lnkd.in/eZ5ue7wH 🔬 Follow us for cutting-edge immunology insights! #Immunology #TLR4 #THP1 #Macrophages #CellCulture #ScientificResearch #Biotech #InvivoGen