Date published: 2025-7-15

1-800-457-3801

SCBT Portrait Logo
Seach Input

MOPS, Free Acid (CAS 1132-61-2)

5.0(1)
Write a reviewAsk a question

See product citations (1)

Alternate Names:
MOPS, Free Acid is also known as 3-(N-morpholino)propanesulfonic acid.
Application:
MOPS, Free Acid is an MES structural analog and buffer agent with a pKa close to physiological pH.
CAS Number:
1132-61-2
Purity:
≥97%
Molecular Weight:
209.26
Molecular Formula:
C7H15NO4S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

MOPS, Free Acid is a buffering agent used by biologists and biochemists in cell culture. For example,it is used in such systems as E. coli, Cryptococcus neoformans, cultured human keratinocytes, and thermophilic methaogenic bacteria. In protein studies, MOPS, Free Acid has been used in an x-ray crystallographic study of the ADP-binding site of succinyl-CoA synthetase from E. coli, in the characterization of the Rieske-type ferredoxin BphF, and in an electron microscopy analysis of the engineered protein betabellin-15D. The pKa of MOPS, Free Acid (7.2) is closer to physiological pH than that of MES (6.1), thus it may be more suitable as a physiologically relevant buffer.


MOPS, Free Acid (CAS 1132-61-2) References

  1. Susceptibility of Cryptococcus neoformans by the NCCLS microdilution and Etest methods using five defined media.  |  Petrou, MA. and Shanson, DC. 2000. J Antimicrob Chemother. 46: 815-8. PMID: 11062205
  2. Sensitivity and specificity of the BAX for screening/Listeria monocytogenes assay: internal validation and independent laboratory study.  |  Hochberg, AM., et al. 2001. J AOAC Int. 84: 1087-97. PMID: 11501909
  3. Gene expression profiling of the pH response in Escherichia coli.  |  Tucker, DL., et al. 2002. J Bacteriol. 184: 6551-8. PMID: 12426343
  4. Survey of retail alfalfa sprouts and mushrooms for the presence of Escherichia coil O157:H7, Salmonella, and Listeria with BAX, and evaluation of this polymerase chain reaction-based system with experimentally contaminated samples.  |  Strapp, CM., et al. 2003. J Food Prot. 66: 182-7. PMID: 12597474
  5. Ultrasensitive reporter protein detection in genetically engineered bacteria.  |  Wells, M., et al. 2005. Anal Chem. 77: 2683-9. PMID: 15859581
  6. Producing human mechano growth factor (MGF) in Escherichia coli.  |  Kuznetsova, TV., et al. 2008. Protein Expr Purif. 58: 70-7. PMID: 18068377
  7. Inhibition of telomerase by G-quartet DNA structures.  |  Zahler, AM., et al. 1991. Nature. 350: 718-20. PMID: 2023635
  8. Nutrient dispersion enhances conventional antibiotic activity against Pseudomonas aeruginosa biofilms.  |  Sommerfeld Ross, S. and Fiegel, J. 2012. Int J Antimicrob Agents. 40: 177-81. PMID: 22727773
  9. Analysis of DNA structures from eukaryotic cells by two-dimensional native-native DNA agarose gel electrophoresis.  |  Ivessa, AS. 2013. Methods Mol Biol. 1054: 63-81. PMID: 23913285
  10. Directionality of replication fork movement determined by two-dimensional native-native DNA agarose gel electrophoresis.  |  Ivessa, AS. 2013. Methods Mol Biol. 1054: 83-103. PMID: 23913286
  11. Effect of membrane depolarization on binding of [3H]nitrendipine to rat cardiac myocytes.  |  Green, FJ., et al. 1985. Circ Res. 56: 576-85. PMID: 2983904
  12. Co-Immobilization of Rhizopus oryzae and Candida rugosa Lipases onto mMWCNTs@4-arm-PEG-NH2-A Novel Magnetic Nanotube-Polyethylene Glycol Amine Composite-And Its Applications for Biodiesel Production.  |  Abdulmalek, SA., et al. 2021. Int J Mol Sci. 22: PMID: 34769395
  13. High-throughput strategy for identification of Mycobacterium tuberculosis membrane protein expression conditions using folding reporter GFP.  |  Grāve, K., et al. 2022. Protein Expr Purif. 198: 106132. PMID: 35750296
  14. Ceramide Kinase (CERK) Emerges as a Common Therapeutic Target for Triple Positive and Triple Negative Breast Cancer Cells.  |  Rajput, K., et al. 2022. Cancers (Basel). 14: PMID: 36139656
  15. Hydrogen ion buffers for biological research.  |  Good, NE., et al. 1966. Biochemistry. 5: 467-77. PMID: 5942950
  16. Buffers of constant ionic strength for studying pH-dependent processes.  |  Ellis, KJ. and Morrison, JF. 1982. Methods Enzymol. 87: 405-26. PMID: 7176924
  17. Bacterial growth medium that significantly increases the yield of recombinant plasmid.  |  Duttweiler, HM. and Gross, DS. 1998. Biotechniques. 24: 438-44. PMID: 9526655

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

MOPS, Free Acid, 100 g

sc-216097
100 g
$46.00
US: (Out of Stock: Availability June 13, 2025)

MOPS, Free Acid, 500 g

sc-216097A
500 g
$175.00

MOPS, Free Acid, 1 kg

sc-216097B
1 kg
$226.00

MOPS, Free Acid, 5 kg

sc-216097C
5 kg
$960.00