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MicroPADs: Affordable Disease Diagnostics

Microfluidic paper-based analytical devices (MicroPADs) provide a new platform for affordable, sensitive, specific, user-friendly, rapid, robust, equipment-free and deliverable diagnostic tests, as outlined by the World Health Organization. MicroPADs are fabricated using wax printing to create hydrophilic channels on paper for fluid flow, allowing for portable and inexpensive multi-analyte detection using small sample volumes. Future work aims to develop alternative low-cost fabrication methods and materials, as well as new signal display techniques for MicroPADs.

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shahanisubhash
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241 views14 pages

MicroPADs: Affordable Disease Diagnostics

Microfluidic paper-based analytical devices (MicroPADs) provide a new platform for affordable, sensitive, specific, user-friendly, rapid, robust, equipment-free and deliverable diagnostic tests, as outlined by the World Health Organization. MicroPADs are fabricated using wax printing to create hydrophilic channels on paper for fluid flow, allowing for portable and inexpensive multi-analyte detection using small sample volumes. Future work aims to develop alternative low-cost fabrication methods and materials, as well as new signal display techniques for MicroPADs.

Uploaded by

shahanisubhash
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PPTX, PDF, TXT or read online on Scribd
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MICROFLUIDIC PAPER-BASED ANALYTICAL DEVICES (uPADS)

A Global Problem
Millions of people die every year from preventable diseases. Effective diagnosis of diseases is the first step towards an appropriate treatment.

Microfluidic PaperBased Analytical Devices (MicroPADs)

Fields of Application

ASSURED Diagnostic Tests


Affordable Sensitive Specific User-friendly Rapid and Robust Equipment-free Deliverable to end-users --World Health Organisation

Channels in Paper

Fabrication by Wax Printing

Advantages and Disadvantages of Wax Printing


Advantages
very simple and fast processes No Special treatment of paper Hydrophilic wax channel is not expose to polymers or solvent

Disadvantages
Extra heating step after deposition Expensive wax printer

Future Challenges
Alternative cheap materials: Paper alternative that performs better or allows more diversity Fabrication techniques: 3D paper- based microfluidics where lateral and vertical flow is possible. Novel signal displays: the use of enzymes on paper to display result in text.

Summary
MicroPADs are a new platform for ASSURED diagnostic tests MicroPADs: are simple to use Detect multiple analytes Are portable Are inexpensive Use small volumes of samples

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