Insulins Available in the United States
Generic Name
(U-100, except where
Brand Name
noted)
Rapid Acting
insulin aspart
NovoLog
Novo Nordisk
analog
insulin human
Afrezza
Sanofi
human
insulin glulisine
Apidra
Sanofi
analog
insulin lispro
Humalog*
Eli Lilly
analog
Regular
Regular
Humulin R+
Novolin R
Eli Lilly
Novo Nordisk
human
human
Humulin N
Eli Lilly
human
Novolin N, ReliOn
(Walmart)
Novo Nordisk
human
Long Acting
insulin detemir
Levemir
Novo Nordisk
analog
insulin glargine
Lantus
Sanofi
analog
Ultra Long Acting
insulin glargine U-300 Toujeo
Sanofi
analog
Humalog Mix 50/50
Eli Lilly
analog
Humalog Mix 75/25
Eli Lilly
analog
Regular
Intermediate Acting
NPH
NPH
Manufacturer
Form
Delivery
syringe; prefilled,
300-unit disposable
pen; reusable pen
with 300-unit
cartridges; pump
inhaler with 4- and
8-unit cartridges
syringe; prefilled,
300-unit disposable
pen; pump
syringe, prefilled
disposable pen,
reusable pen with
cartridges, pump
Cloudy or Clear
10 to 20 min.
Peak
Duration
30 to 90 min.
3 to 5 hours
N/A (inhaled powder) 10 to 20 min.
12 to 15 min.
3 hours
clear
10 to 20 min.
30 to 90 min.
3 to 5 hours
clear
10 to 20 min.
30 to 90 min.
3 to 5 hours
syringe
syringe
clear
clear
30 to 60 min.
30 to 60 min.
2 to 4 hours
2 to 4 hours
5 to 8 hours
5 to 8 hours
syringe; prefilled,
300-unit disposable
pen
syringe
cloudy
1 to 3 hours
8 hours
12 to 16 hours
cloudy
1 to 3 hours
8 hours
12 to 16 hours
clear
1 hour
No peak
20 to 26 hours
clear
1 hour
No peak
20 to 26 hours
prefilled, 300-unit
disposable pen
clear
6 hours
No peak
36 hours
syringe; prefilled,
300-unit disposable
pen
syringe; prefilled,
300-unit disposable
pen
syringe; prefilled,
300-unit disposable
pen
syringe; prefilled,
300-unit disposable
pen
syringe
cloudy
10 to 15 min.
Varies
10 to 16 hours
cloudy
10 to 15 min.
Varies
10 to 16 hours
cloudy
5 to 15 min.
Varies
10 to 16 hours
cloudy
30 to 60 min.
Varies
10 to 16 hours
cloudy
30 to 60 min.
Varies
10 to 16 hours
clear
clear
30 min.
15
8 hours
30 to 90 min.
Up to 24 hours
3 to 5 hours
syringe; prefilled,
300-unit disposable
pen
syringe; prefilled,
300-unit disposable
pen
clear
Onset
Mixtures
50% lispro protamine/50% insulin
lispro
75% lispro protamine
(NPL)/25% insulin
lispro
70% aspart protamine/30% insulin
aspart
70% NPH/30%
Regular
NovoLog Mix 70/30 Novo Nordisk
analog
Humulin 70/30
Eli Lilly
human
Novo Nordisk
human
Eli Lilly
Eli Lilly
human
analog
70% NPH/30%
Novolin 70/30,
Regular
ReliOn (Walmart)
Less Commonly Used Insulins
regular U-500
Humulin R U-500 +^
insulin lispro U-200
Humalog U-200*^
syringe
prefilled, 600-unit
disposable pen
Key
Note difference between Humalog and Humalog U-200. + Note difference between Humulin R and Humulin R U-500. Note difference between Novolin 70/30 (70% NPH/30% Regular) and NovoLog Mix
*70/30
(70% aspart protamine/30% aspart). U-100, U-200, U-300, and U-500 are different concentrations of insulin. Higher concentrations are typically used in very insulin-resistant people.
