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Cycles: Following Topics Are Important in Bio-Chemistry Section

The document outlines important topics to focus on in biochemistry, including metabolic cycles like glucose, lipids, proteins, and nucleotides; protein and collagen structure; recent lab techniques found in Robbins Pathology; genetics techniques; and inborn errors of metabolism. Key areas of inborn errors include glycogen storage disorders, galactosemia, hereditary fructose intolerance, maple syrup urine disease, phenylalanine metabolism, lysosomal storage diseases like Gaucher's disease and Niemann Pick disease, and mucopolysaccharidosis. Enzyme replacement therapies exist for some inborn errors of metabolism.

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37 views2 pages

Cycles: Following Topics Are Important in Bio-Chemistry Section

The document outlines important topics to focus on in biochemistry, including metabolic cycles like glucose, lipids, proteins, and nucleotides; protein and collagen structure; recent lab techniques found in Robbins Pathology; genetics techniques; and inborn errors of metabolism. Key areas of inborn errors include glycogen storage disorders, galactosemia, hereditary fructose intolerance, maple syrup urine disease, phenylalanine metabolism, lysosomal storage diseases like Gaucher's disease and Niemann Pick disease, and mucopolysaccharidosis. Enzyme replacement therapies exist for some inborn errors of metabolism.

Uploaded by

sugiswe
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as PDF, TXT or read online on Scribd
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Following topics are important in Bio-Chemistry section:

1. Cycles
These are very important from examination perspective and must be revised
one night before the exam since these are very volatile.

You must focus on preparing various cycles like Glucose, Lipids, Protein and
Neucleotide.

You must focus on Enzymes, Substrates and cycles of Inborn errors of


Metabolism.

1. Protein Structure and Collagen Structure


This is the second part which is really important from the examination
perspective.

Important Topics Under Protein Structure

 Types of Protein Structure


 Tests used to detect them
Important Topics Under Collagen Structure

 Sequence of Collagen Structures

1. Recent Lab Techniques


Generally 1-2 questions are covered from this section in the exam.

The recent lab techniques can be studied from the latest edition of Robbin’s
Pathology since questions are directly framed from this book.

1. Genetics
This is a really important topic. Aspirants can prepare genetics from Pathology
book or Bio-Chemistry book.

Toppers’ highlighted that aspirants who are currently in the profs should
prepare Genetics from Robbin’s Pathology since it’s given in detail there.
Candidates who are in internship and have limited time can refer to a good
Biochemistry guide for genetics. Most important topic in genetics is techniques,
since new questions appear from this part.

1. Inborn errors of Metabolism


Metabolism is a very important topic of paediatrics but can be covered under
biochemistry also.

Most Important Topics under Carbohydrate Metabolism

 Glycogen storage Disorders


 Galactosemia
 Hereditary Fructose Intolerance
Most Important Topics under Disorders of Amino Acid

 Maple Syrup urine disease


 Phenylalanine Metabolism
Lysosomal Storage Diseases

Important topics under this include:

 Most Common Gauchers


 Niemann Pick Disease
 Gangliosidosis
 Mucopolysaccharidosis – Image Based questions
Enzyme Replacement therapies are available for some of the inborn errors of
metabolism.

This is a hot favourite new topic asked in the exam and the aspirants must be
aware of the disorders for which the treatment exists.

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