Drug (generic Usual Drug Action:
& trade name) Dosage/Route
Reduces gastric acid secretion and decreases gastric acidity.
Generic: P.O & IV
Esomeprazole Capsules
Magnesium (delayed-
release): 20, 40
Trade: mg
Nexium Powder for
Nexium IV suspension
(delayed-
release): 10, 20,
40 mg
Powder for
injection: 20, 40
mg single-use
vials
Class:
proton pump inhibitor
gastric acid suppressant
Side Effects:
CNS: headache, dizziness
GI: abdominal pain, constipation, diarrhea, dry mouth, flatulence, nausea, vomiting
Respiratory: sinusitis, respiratory infection
Skin: pruritus
Nursing Considerations:
• Antacids can be used while taking drug, unless otherwise directed by prescriber.
• Monitor patient for rash or signs and symptoms of hypersensitivity.
• Monitor GI symptoms for improvement or worsening.
• Monitor liver function tests, especially in patients with preexisting hepatic disease.
• Amoxicillin may trigger anaphylaxis in patients with a history of penicillin hypersensitivity.
• Long-term therapy may cause atrophic gastritis.
Patient Teaching:
• Instruct patient to take drug exactly as prescribed.
• Tell patient to take drug at least 1 hour before a meal.
• Advise patient that antacids can be used while taking drug unless otherwise directed by prescriber.
• Warn patient not to chew or crush drug pellets because this inactivates the drug.
• If patient has difficulty swallowing capsule, tell him to mix contents of capsule with 1 tablespoon of soft
applesauce and swallow immediately.
• Advise patient to store capsules at room temperature in a tight container.
• Tell patient to inform prescriber of worsening signs and symptoms or pain.
• Instruct patient to alert prescriber if rash or other signs and symptoms of allergy occur.
Date of Reason Drug Prescribed for this patient:
Care (document each time drug card used for a patient – save document throughout nursing program)