Biology PDF
Biology PDF
   The science of biology is so vast and extensive that biology is so vast and extensive that biologist
    divide it into several branches to facilitate the study of living organism and their relationship
    with other living and non-living entities.
   Biology has two basic branches – Botany and Zoology. Botany is the study of plants while
    Zoology is the study of animals.
   All living organisms are composed of one or many cells to perform their individual function. A
    cell is the basic unit of life, which is able to control and perform several functions in living
    organicm.
   The largest cell in the human body is the female egg cell ovum while the smallest cell in the
    human body is ovum, “sperm”.
   The longest cell in the human body is the “nerve cell”.
 The largest known cells are unfertilized ostrich egg cells which weigh 3.3 pounds.
   The smallest type of cell in the world is the mycoplasma bacterium with only a diameter of 10
    um (micrometre).
       There are two primary types of cells- Prokaryotic cells and Eukaryotic cells.
       Capsule: It is composed of a thick polysaccharide. It is a kind of smile layer, which covers the
        outside of the cell wall. It is used to stick cells together and works as a food reserve and it also
        protects the cell from dryness and from chemicals.
       Cell wall: it is made from the glycoprotein merein. Cell wall provides strength and rigidity to
        the cell and it is permeable to solutes.
       Cytoplasm: It helps in cellular growth, metabolism and replication. Cytoplasm is the storehouse
        for all types of chemicals and components that are used to sustain the life of a bacterium.
       Cell wall: It helps in protecting the plasma membrane and plays a vital role in supporting and
        protecting the cells. It is a thick outer layer made of tough cellulose. Cell walls are present in
        plant cells and are absent in animal cells.
       Plasma membrane: The plasma membrane is present in animal cells, plant cells and even in
        eukaryoticcells. It is a double-layered thin barrier, surrounding the cell that controls the entry
        and exit of certain substances.
       Nucleus: It is present both in the animal and plant cells. It is large and present in the centre of a
        cell. It contains DNA and stores all the necessary information, which is required to control all the
        activities within the cell. Hence it is also called as a “brain of the cell”.
       Nuclear membrane: It is double-layered, which surrounds the nucleus and helps in the entry
        and exit of material into the nucleus. It also separates the nucleus from the other parts of the
        cell.
       Nucleolus: It is present in the nucleus of both plant and animal cells. it plays a vital role in the
        synthesis of RNA and in the formation of the ribosome.
      Robert Brown first discovered the nuclei (plural form of nucleus) in the cells way back in 1831.
      Mitochondria: The organelles that convert energy into usable forms, which are used by the cell
       to perform their cellular functions. It is a “powerhouse of the cell”, which produces energy by
       breaking down fats and carbohydrates. It converts glucose to ATP.
      Chloroplast: They are the sub-cellular sites of photosynthesis.
      Ribosomes: They are biological molecules, which are composed of proteins and RNA. It plays a
       vital role in the synthesis-millions of protein.
      Golgi Bodies: They are sac-like structure, which are specifically used for storing or preserving all
       the substances made by the cell.
      Lysosomes: They are spherical organelles, which contain enzymes that help in maintaining the
       physiological activities of cellular constituents. They protect the cell by ingestion of other dying
       cells or larger extracellular material like-foreign invading microbes. Without lysosomes, living
       organism would become filled with dead cells.i.e Lysosomes are called “suicidal bags”.
      Vacuoles: They are vesicle that help in the digestion. They are present both in plant and animal
       cells.
      Cytoplasm: It refers to the jelly-like material with organelles in it. It is present both in plant and
       animal cells. They consist of inner region of the plasma membrane and also the outer region of
       DNA. A cytoplasm plays a vital role in storage and manufacturing of energy.
      Chromosomes are small, coloured thread-like structures present in the nucleoplasm of living
       cells, which help in the inheritance or transmission of characters in the form of genes from one
       generation to another generation.
      Centrosomes: They are small hollow cylindrical shaped organelles, which are composed of nine
       bundles of micro tubules. They play a vital role in the cell division or in the cell cycle.
Nucleic Acids
      Nucleic acids are long biological macromolecules that consist of smaller molecules called
       nucleotides.
      Nucleic Acids are DNA and RNA, they carry genetic information in the cell.
       In DNA and RNA, these nucleotides contain four nucleobases-sometimes called nitrogenous
        bases or simply bases-two purine and pyrimidine bases each.
 They also help in synthesis of proteins, through the process of translation and transcription.
        A nucleic acid that contains the genetic instructions used in the development and functioning
         of all modern living organisms(scientists believe that RNA may have been the main genetic
         material in primitive life forms).
        Double-standed. It has two nucleotide started which consist of its phosphate group, five-
         carbon ugar (the stable 2-deoxyribose), and four nitrogen-containing nucleobases: adenine,
         thymine, cytosine, and guanine.
        Pairing of Bases: A-T (Adenine-Thymine), G-C(Guanine – Cytosine)
        DNA is self-replicating.
        DNA was first identified and isolated by Friedrich Miescher (Friedrice Mixture)and the double
         helix structure of DNA was first discovered by James Watson and Francis Crick. (Watson
         Cricket)
Ribo Nucleic Acid (RNA)
       The information found in DNA determines which traits are to be created, activated, or
        deactivated, while the various forms of RNA do the work.
       RNA is a single polynucleotide chain composed of nucleotides of adenine, guanine, cytosine and
        uracil. Thymine nucleotides are absent.
       RNA occurs mostly in the cytoplasm in the eukaryotic cells. A small amount occurs in the
        nucleus of the cell, as a constituent of nucleolus.
       Single-standed. Like DNA, RNA is composed of its phosphate group, five-carbon sugar (the less
        stable ribose), and four nitrogen-containing nucleobases: adenine, uracil (not tymine), guanine,
        and cytosine.
       Pairing of Bases: A-U(Adenine-Uracil), G-C(Guanine-Cytosine).
       RNA is synthesized from DNA when needed.
Cell Division
       Cell division is a process with sequence of steps that enables organism to grow and reproduce.
Mitosis
         The process by which a cell which has previously replicated chromosomes in the nucleus of the
          cell is separated into two identical sets of chromosomes id known as mitosis.
         Mitosis is the division of the mother cell into two daughter cells, these daughter cells are
          genetically identical to each other and to the parent cell. It is a form of nuclear division.
         Mitotic division of cell is unchecked and it may result in uncontrolled growth of cells leading to
          cancer or tumor.
Meiosis
Carbohydrates
        Carbohydrates are good sources of energy.
        Carbohydrates (polysaccharides) are long chains of sugars.
        Ribose and deoxyribose sugars from the structural frame of the genetic materials, RNA and
         DNA.
        They have a free aldehyde or ketone group, which act as reducing agents and are known as
         reducing sugars.
        Carbohydrates provide the body with source of fuel and energy, it aids in proper functioning of
         our brain, heart and nervous, digestive and immune system.
        Deficiency of carbohydrates in the diet causes fatigue, poor mental function.
        Oligosaccharides are compound such that yield 2 to 10 molecules of the same or different
         monosaccharides on hydrolysis. Oligosaccharides yielding 2 molecules of monosaccharides on
         hydrolysis is known as a disaccharides and tetrasaccharides respectively Examples: Maltose,
         lactose, sucrose, raffinose, stachyose.
        Polysaccharides are compounds of sugar and yield more than 10 molecules of monosaccharides
         on hydrolysis. Examples: Starch, glycogen, cellulose, pectin, inulin, hyaluonic acid
Lipids
Proteins
      Proteins are organic substances, they are made up of nitrogen and oxygen, carbon and
       hydrogen.
      Proteins are the most important biomolecules, they are the fundamental constituents of the
       cytoplasm of the cell.
      Proteins are made up of amino acids.
      Proteins give heat and energy to the body and also aid in building and repair.
      Only small amounts of proteins are stored in the body as they can be used up quickly on
       demand.
       The types of proteins are as follows:
      Hormones are the proteins-based chemicals that are secreted by the endocrine glands.
       Hormones are chemical messengers that transmit signals from one cell to the other.
      Enzymatic proteins accelerate the metabolic activity in the cells.
      Structural proteins are necessary components of the body. Structural proteins like collagen
       form connective framework in body tissue, and keratin is main component of hair, skin and
       nails.
      Defensive proteins like antibodies and immunoglobulins are the core parts of the body’s
       immune system.
      Storage proteins store mainly mineral ions in the body, like potassium, iron etc.
      Transport proteins carry vital materials to the cells.
      Receptor proteins are located on the outer part of the cells, they control te substances that
       leave and enter the cell.
      Contractile proteins control the strength and speed of heart and muscle contractions.
Roughage
      Roughage or Dietary fibre is cellulose (the part of a plant) which cannot be digested by the
       human intestinal tract.
      It retains water and improves intestinal function by adding bulk to food. It is a definite necessity
       for proper digestion and bowel movement.
      Roughage helps correct large intestine disorders and keeps it functioning normally. It prevents
       constipation and haemorrhoids.
Vitamins
      Organic compounds required in the diet in small amounts to maintain normal health, growth
       and nutrition.
      Water-soluble vitamins: Vitamin A, D, E and K.
      The body can also synthesise vitamin D (specifically cholecalciferol) in the skin, from cholesterol,
       when Sun exposure is adequate (hence its nickname, the “sunshine vitamin”).
Mineral nutrients
Digestive System
      The human digestive system is a complex process that consists of breaking down large organic
       masses into smaller particles that the body can use as fuel.
      The breakdown of the nutrients requires the coordination of several enzymes secreted from
       specialized cells within the mouth, stomach, intestine, and liver.
      Alimentary canal is a long continuous tube constituted by mouth, pharynx, oesophagus,
       stomach, small intestine, large intestine, and rectum.
      The glandular organs, salivary glands, liver and pancreas and the alimentary canal from the
       digestive system.
      The mouth, which includes:
      The Teeth, which grind food to increase the surface area. The teeth are 32 small, hard organs
       found along the anterior and lateral edges of the mouth.
      Taste Areas of Human Tongue
      The Tongue: It tastes and manipulates the food. The taste buds on the surface of the tongue
       detect taste molecules in food and connect to nerves in the tongue to send taste information to
       the brain. The tongue also helps to push the food towards the posterior part of the mouth for
       swallowing.
      Salivary Glands: Surrounding the mouth are 3 sets of salivary glands. The saliva, which includes
       mucin, a lubricant; buffers to neutralize acidic foods, antibacterial agents, and amylase, which
       converts starch to maltose.
      Pharynx, which in humans, leads to both the trachea and the oesophagus. The pharynx is
       responsible for the passing of masses of chewed food from the mouth to the oesophagus. While
       food is being swallowed, the epiglottis block the trachea and the uvula blocks off the nose.
      The Oesophagus, which is the tube from the pharynx to the stomach. There is no digestion in
       this part, also called gullet. Food is moved along the Oesophagus by peristalsis, wave-like
       contractions of the muscles in the walls of the oesophagus. The lining of the oesophagus secrets
       mucus to lubricate the ball of food. There are sphincter muscles (rings of constricting muscles)
       at the top and bottom of the oesophagus.
      The Stomach is a J-shaped, expandable sack, normally on the left side of the upper abdomen.
       The stomach contains hydrochloric acid strong enough to dissolve metal (pH about 1.5 to 3,
       usually around 2), which kills bacteria and helps denature the proteins in our food, making them
       more vulnerable to attack by pepsin.
      Small Intestine: The food moves from the stomach to duodenum, which is the upper part of the
       small intestine. The small intestine is a long, thin tube about 1 inch in diameter and about 10
       feet long that is part of the lower gastrointestinal tract.
      Liver and Gallbladder: The liver weight about 3 pounds and is the second largest organ in the
       body. The liver has main different functions in the body, but the main function of the liver in
       digestion is the production of bile and its secretion into the small intestine so that it can be
       reused for the digestion of subsequent metals.
      Pancreas: The pancreas is a large gland ocated just interior and posterior to the stomach. The
       pancreas secrets digestive enzymes into the small intestine to complete the chemical digestion
       of foods.
      The pancreatic juice contains three enzymes.
      Trypsin – converts peptones and proteoses to smaller peptides.
      Amylase – converts starch into matose.
      Lipase – converts facts into fatty acids and glycerol.
      The digestion of proteins into the end products as amino acids, carbohydrates into glucose and
       fats into fatty acids and glycerol is completed in the small intestine.
      Large Intestine: The large intestine long, thick tube about 2 ½ inches in diameter and about 5
       feet long. The large intestine absorbs water and contains and many symbiotic bacteria that aid
       in the breaking down of wastes to extract some small amounts of nutrients. The process by
       which the undigested food material or waste is released from the body is called egestion.
Digestive Enzymes
      Digestive enzymes function in chemical digestion. It begins in the mouth and ends in the small
       intestine.
      No chemical digestion in the large intestine. Bacteria here are producers of vitamin B and K.
Respiratory System
      The act of breathing includes: inhaling and exhaling air in the body; the absorption of oxygen
       from the air in order to produce energy; the discharge of carbon dioxide, which is the byproduct
       of the process.
      The normal respiratory rate for adults and children over the age of 12 usually ranges from 14 to
       18 breaths per minute.
      Inhalation: (drawing the air inwards) is the result of increasing in the volume of the thoracic
       cavity.
      Exhalation: is the result of decrease in the volume of the thoracic cavity.
      Internal nostrils open into pharynx.
      The opening of the pharynx into the trachea is called glottis.
      Trachea: Located just below the larynx, the trachea is the main airway to the lungs. Trachea is
       thin walled but its walls do not collapse even when there is not enough air in it as it is supported
       by rings of cartilage. Trachea bifurcates into bronchi.
      Bronchi: The bronchi branch from the trachea into each lung and create the network of intricate
       passages that supply the lungs with air.
      Lungs: Together the lungs from one of the body’s largest organ. They’re responsible for
       providing oxygen to capillaries and exhaling carbon dioxide.
      Alveolus: Alveolus is the tiny sac-like structure present in the lungs in which the gaseous
       exchange takes place.
      Diaphragm: The diaphragm is the main respiratory muscle that contracts and relaxes to allow air
       into the lungs.
      The right lung is larger than the left lung.
      We inhale and exhale about 500 ml of air per breath. This value is called the tidal volume.
      Even after a very strong exhalation, about 1000 to 1200 mL of air remains in the lungs. This is
       known as residual volume.
      Breathing is the physical process of respiratory gaseous exchange between the organism and
       the environment by diffusion. On the other hand, respiration involves oxidation of food and
       release of energy along with respiratory gaseous exchange.
      Another name for the larynx is the voice box or the Adam’s apple, and the larynx is what gives
       you your voice.
Aerobic respiration:
Circulatory System
      The circulatory system is known as a double circulatory system, this is because it is made up of
       two interweaving loops and blood passes through the heart twice. The heart is at the centre of
       this system. The heart is divided into two havels, the right and the left. Bold from these two
       halves never mix.
The Heart
      The heart is cone-shaped organ made up of cardiac muscle called myocardium tissue.
      The contraction and relaxation follows a rhythm called heart beat. Heart pumps blood into the
       blood vessels. The heart beats or contracts approximately times per minute.
      The systemic contraction of the heart is called Pulse rate which is the same as the rate of heart
       beat.
      The human heart is a two-sided, 4 chambered structure with muscular walls.
      An atrioventricular (AV) valve separates each auricle from ventricle.
      A semilunar (also known as arterial) valve separates each (ventricle from its connecting artery.
      Auricles or Atria refer to the upper chambers of the heart (2 in number) that receive the
       impure blood from the veins to send it to the ventricles.
      Ventricles are lower two chambers that accept blood from the arteries (left atrium) and then
       contracts to force into the aorta.
      The walls of the ventricles are thicker and contain more cardiac muscle than the walls of the
       atria. This enables the ventricles to pump out blood to the lungs and the rest of the body.
      The right chamber of the heart accepts deoxygenated blood that is carried by the right aorta.
      The left side of the heart is concerned with the oxygenated blood.
      Atria collect blood from veins.
      Atria contract, atrioventricular valve open.
      Blood is pumped into ventricles.
      Ventricle contracts, atrioventricular valves close and semilunar valves open.
      Blood is pumped into arteries, semilunar valve close.
      Cycle repeats.
      In the human heart, contraction is initiated by a special modified heart muscle known as
       sinoatrial node. It is located in the right atrium. The SA node has the inherent power of
       generating a wave of contraction and controlling the heartbeat. Hence, it is known as the
       pacemaker.
      Since the heart beat is initiated by the SA node and the impulse of contraction originates in the
       heart itself, the human heart is termed myogenic.
      When the sinoatrial node becomes defective, the heart may beat too fast, too slow, or
       irregularly. An artificial pacemaker is used to treat a dangerously slow heart rate to help it beat
       at a more healthy rate.
Arteries
       Arteries carry oxygenated blood (with the exception of the pulmonary artery and umbilical
        artery).
       Direction of blood flow from the heart to various parts of the body.
       Thick outer layer of longitudinal collagen and elastic fibers prevents leaks and bulges.
       Thick wall withstands high pressure.
       Thick layers of circular elastic fibers and muscle fibers to pump blood.
       Narrow lumen to maintain high pressure.
Veins
          Veins carry deoxygenated blood (with the exception of pulmonary veins and umbilical vein).
          Direction of blood flow from various parts of the body to the heart.
          Thin walls so that nearby muscles can help push blood towards the heart.
          Thin outer layer of longitudinal collagen and elastic fibers as pressure is low.
          Wide lumen to accommodate the slow-flowing blood.
Capillaries
       Capillaries are the smallest and thinnest of the blood vessels and serve as the connection
        between the arterial and venal system of the cardiac system.
       They are only one-cell thick, and they are the sites of the transfer of oxygen and other nutrients
        from the bloodstream to other tissues in the body.
       They also collect carbon dioxide waste materials and fluids for return to the veins.
Blood
       Blood is a mixture of two components: cells and plasma. The heart pumps blood through the
        arteries, capillaries and vein to provide oxygen and nutrients to every cell of the body. The blood
        also carries away waste products.
       Plasma is the liquid component of blood, in which the red blood cells, and platelets are
        suspended. It constituents more than half of the blood’s volume and consists mostly of water
        that contains dissolved salts (electrolytes) and proteins.
       Red blood cells (also called erythrocytes) make up about 40 % of the blood’s volume. Red blood
        cells contain hemoglobin, a protein that gives blood its red colour and enables it to carry oxygen
        from the lungs and deliver it to all body tissues.
       White blood cells (also called leukocytes) are fewer in number than red blood cells, with a ratio
        of about 1 white blood cell to every 600 to 700 red blood cells. White blood cells are responsible
        primarly for defending the body against infection.
       Platelets (also called thrombocytes) are cell-like particles that are smaller than red or white bold
        cells. Platelets are fewer in number than red blood cells, with a ratio of about 1 plarelets to
        every 20 red blood cells. Platelets help in the clooting process by gathering at a bleeding site and
        clumping together to form a plug that helps seal the blood vessel.
       People living at higher altitudes have more red blood cells than other people who live at lower
        altitudes. People living at higher altitudes are used to the lower density of oxygen molecules in
        the air. They have higher levels of haemoglobin (red blood cells) in their blood which helps them
        to take in more oxygen.
       Normal reference ranges for haemoglobin for children, men and women are 11-13 g/dL, 14-18
        g/dL, and 12-16 g/dL respectively.
       A sphygmomanometer or blood pressure meter is a device used to measure blood pressure.
        Normal blood pressure is at or below 120/80.
       Every human being belongs to one of four blood groups: A, B, AB and O.
      Blood transfusion can be between matching blood group O can donate blood to all and ‘O’
       group is called universal donor and AB group can receive blood from all and is called universal
       recipient.
Skeletal System
      Skeletal system is the system of bones, associated cartilage and joints of human body.
      The adult human body has 206 bones.
      In addition to bone, the skeleton also consists of cartilage and ligaments.
      Cartilage is a type of dense connective tissue, made of tough protein fibers, that provide a
       smooth surface for the movement of bones at joints.
      A ligament is a band of fibrous connective tissue that holds bones together and keeps them in
       place.
      Joints are important components of human skeleton because they make the human skeleton
       mobile. A joint occurs between “two or more bones”, “bone and cartilage” and “cartilage and
       cartilage”.
Axial Skeleton
      The axial skeleton consists of the 80 bones along the central axis of the human body.
      Skull (29 bones) – includes bones of the cranium, face, and ears (auditory ossicles).
      Hyoid – U -shaped bone or complex of bones located in the neck between the chin and larynx.
      Vertebral Column (33 vertebrae) – includes spinal vertebrae.
      Thoracic Cage (12 pairs) – includes ribs and sternum (breast bone).
Appendicular Skeleton
      The appendicular skeleton is composed of 126 bones in the human body involved in locomotion
       (lower limbs) of the axial skeleton and manipulation of objects in the environment (upper
       limbs).
      Pectral Girdle (2 bones) – includes shoulder bones (clavicle and scapula).
      Upper Limbs (64 bones) – include bones of the arms and hands.
      Pelvic Girdle (2 hip bones) – includes hip bones.
      Lower Limbs (62 bones) – include bones of the legs and feet.
      The longest bone in the human body is the thigh bone called the femur.
      The smallest bone found in the human body is located in the middle ear. The staples (or stirrup)
       bone is only 2.8 millimeters (0.11 inches) long.
      The area of our body with the most bones is the hand, fingers and wrist where are 54 bones.
      Our teeth from part of the skeletal system, but are not counted as bones.
      Bone marrow makes up 4% of a human body mass. It produces red blood cells which carry
       oxygen all over the body. Marrow also produces lymphocytes, key components of the lymphatic
       system, which support the body’s immune system.
Excretory System
       In human beings, excretion is carried out by an organ system known as the urinary system or the
        excretory system.
       It has the following parts:
       Two bean-shapped kidneys, located below the diaphragm in the abdomen and towards the
        back.
       Two excretory tubes or ureters (one from each kidney).
       One urinary bladder, ureters open into it.
       A muscular tube called urethra arises from the bladder. The urinary opening is at the end of
        urethra.
       Filtration and reabsorption are two important processes of excretion.
       Kidneys not only excrete nitrogenous wastes but also regulate the water content of the body
        (osmoregulation), and keep the normal mineral balance in the blood.
       A nephron is the structural and functional unit of the kidney.
The Urine
      The functioning of the nervous system depends on detecting a stimulus in the internal or
       external environment and responding to it.
      Central Nervous System (CNS) is regarded as the “information processor” in the body. It consists
       of the brain lying under the skull, and the spinal cord contained within the vertebral column.
      The neuron is the basic unit of nervous system. There are three types of neurons – sensory,
       motor and association or connecting neurons.
      In total, there are 43 main nerves that branch of the CNS to the peripheral nervous system (the
       peripheral system is the nervous system outside the CNS. These are the efferent neurons that
       carry signals away from the CNS to the peripheral system.
      These efferent fibers are divided into the somatic nervous system and the autonomic nervous
       system.
      The somatic fibers are responsible for the voluntary movement of our body, i.e. movement that
       you consciously through about doing.
      The autonomic nervous system (ANS) consists of two sets of motor neurons and a collection of
       ganglia. The autonomic nervous system incorporates all the impulses that are done
       involuntarily, and are usually associated with essential functions such as breathing, heartbeat
       etc.
      The peripheral nervous system is made up of nerves that connect the different parts of the
       body (peripheral tisues) to the central nervous system.
The Brain
      The brain consists of three important parts: Cerebrum, Cerebellum and Medulla.
      Cerebrum: It is the largest portion of the brain, vertically divided into two halves: right and left
       cerebral hemispheres. It controls all voluntary actions.
      Cerebellum: The main function of the cerebellum is to maintain the balance of the body and
       coordinate muscular activity.
      Medulla Oblongata: It is the lower portion of the brain located at the base of the skull. It is
       roughly triangular and is continued behind as the spinal cord. Its function is to control the
       activities of our visceral organs like the alimentary canal, movement, breathing, beating of heart
       and many other involuntary actions.
      The spinal cord extends from the medulla oblongata and continues downward almost
       throughout the length of the backbone. It is concerned with the following three functions:
       1) it controls the reflexes below the neck.
       2) It conducts sensory impulses from the skin and muscles to the brain, and
       3) It conducts motor responses from the brain to muscles of the trunk and limbs.
         The thalamus is the part of the brain that relays pain and pressure impulses. It is called
          Gatekeeper to the cerebrum because all sensory impulses pass to cerebrum through thalamus
          except olfactory impulse.
         The hypothalamus is the part of the brain that helps maintain homeostasis in the body. It
          controls involuntary functions such as hunger, thirst, sweating, fatigue, sexual desire,
          ‘temperature regulation and effecting the pituitary glands it acts as middleman between
          nervous and endocrine system.
Sensory Organs
The Eye
         The Sclerotic Coat: This tough layer creates the “white” of the eye except in the front where it
          forms the transparent cornea.
         Choroid Coat: This middle layer is deeply pigmented with melanin. It reduces reflection of stray
          light within the eye. The choroid coat forms the iris in the front of the eye.
         The Retina: The retina is the inner layer of the eye. It contains the light receptors, the rods and
          cones (and thus serves as the “film” of the eye).
      The human eye and brain together translate light into colour. The human eye can distinguish
       about 10 million different colors.
      Collectively, the photoreceptors in the human eye are most sensitive to wavelengths of light, in
       a vaccum or in air, between 530 and 555 nanometers, which is yellowish-green light.
Eye Defect
      Farsightedness (hypermetropia): If the eyeball is too short or the lens too flat of inflexible, the
       light rays entering the eye – particularly those from nearby objects – will not be brought to a
       focus by the time they strike the retina. Eyeglasses with convex lenses can correct the problem.
      Nearsightedness (Myopia): If the eyeball is too long or the lens too spherical, the image of
       distant objects is brought to a focous in front of the retina and is out of focous again before the
       light strikes the retina. Nearby objects can be seen more easily. Eyeglasses with concave lenses
       correct this problem by diverging the light rays before they enter the eye.
      Cataracts: One or both lenses often become cloudy as one ages. When a cataract seriously
       interferes with seeing, the cloudy lens is easily removed and a plastic one substituted. The entire
       process can be done in a few minutes as an outpatient under local anaesthesia.
Correction be done by focal lens
      Presbyopia is a condition where, with age, the eye exhibits a progressively diminished ability to
       focus on near objects.
         The ear is made up of three parts: the outer, middle, and inner ear.
         All three parts of the ear are important for detecting sound by working together to move sound
          by working together to move sound from the outer part through the middle and into the inner
          part of the ear.
         The main purpose of the ear is to turn sound waves from the air into electrical signals that are
          interpreted by the brain through the eighth cranial nerve.
         Humans can hear sounds waves with frequencies between 20 and 20,000 Hz.
         Normal hearing is at least 20 dB or better. A mild loss is 20-40 dB, moderate loss is 40-60 dB, and
          severe loss is 60-80 dB.
         Ears also help to maintain balance.
Reproductive System
         The purpose of the organs of the male reproductive system is to perform the following
          functions:
         To produce, maintain, and transport sperm (the male reproductive cells) and protective fluid
          (semen)
         To discharge sperm within the female reproductive tract during sex
         To produce and secrete male sex hormones responsible for maintaining the male reproductive
          system
Female Reproductive System
      The female reproductive structures serve to produce eggs, move the fertilized egg, support a
       growing embryo, and provide a birth canal.
      It produces the female egg cells necessary for reproduction, called the ova or oocytes.
      The system is designed to transport the ova to the site of fertilization.
      Conception, the fertilization of an egg by a sperm, normally occurs in the fallopian tibes.
      The next step for the fertilized egg is to implant into the wall of the uterus, beginning the initial
       stages of pregnancy.
      The placenta is an organ that connects the developing foetus to the uterine wall to allow
       nutrient uptake, waste elimination, and gas exchange via the mother’s blood supply, fights
       against internal infection and produces hormones to support pregnancy.
Endocrine System
      The endocrine system acts with nervous system to coordinate the body’s activities.
      Both systems enable cells to communicate with others by using chemical messengers.
      The endocrine system uses chemical messengers called harmones that are transported by the
       circulatory system (blood). They act on target cells that may be anywhere in the body.
      The endocrine system is slower than the nervous system because harmones must travel through
       the circulatory system to reach their target.
      The hypothalamus is part of the brain. It maintains homeostasis (constant internal conditions)
       by regulating the internal environment (examples: heart rate, body temperature, water balance,
       and the secretions of the pituitary gland).
      Endocrine glands are also called ductless glands because they secrete hormones directly into
       the bloodstream.
      Kinds of Hormones: On the basis of their chemical structure
      Peptide hormones are composed of amino acids. A peptide harmone binds to a cell-surface
       receptor, it does not enter the cell. For example : Insulin and growth hormone.
      Steroid hormones enter the cell and bind to receptors in the cytoplasm. The harmone-receptor
       complex enters the nucleus where it binds with chromatin and activites specific genes. For
       example: Testosterone and cortisol.
      Tropic hormones: When the hormones have other endocrine glands as their targets, they are
       called as Tropic hormones. Pituitary or the master gland secretes majority of the tropic
       hormones also Thyroid gland.
      Non-tropic hormones: These hormones directly stimulate the target cells to induce the effect.
       Most endocrine glands such as adrenal glands, pancreas, testis and ovary produce ono-tropic
       hormones. Growth hormone, Oxytocin, Prolactin and melanocyte stimulating hormone (MSH)
       produced from pituitary gland are also non-tropic hormones.
       Major human endocrine glands include:
      Hypothalamus
      Pituitary gland
      Parathyroid glands
      Adrenal glands
      Pineal gland
      Thyroid gland
      Pancreas
      Gonads
      Some common disorders associated with the endocrine glands
Thyroid Gland
Parathyroid Gland
Adrenal Gland
Origin of Life
      The formation of “first cell” on planet Earth is explained by the theory of chemical evolution
       proposed by Oparin and Haldane, independently.
      According to this theory, the reducing atmosphere of primitive Earth helped in the formation of
       simple inorganic compounds followed by simple organic compounds. Then, complex organic
       compounds and subsequently their interaction leading to the formation of self-duplicating
       nuclei acids.
      The nucleic acids and other macromolecules became surrounded by membrane to form the
       protocells.
      The first form of life was probably prokaryotic chemo -autotrophs (cyanobacteria) are said to
       have appeared about 3.5 billion years ago.
      Life is said to have originated in water, because of its unique properties.
      The origin of life was followed by organic evolution with the appearance of well adapted newer
       form of life from the pre-existing simple form of life.
      Father of Zoology is Aristotle.
Organic Evolution
      Organic evolution refers to the slow and gradual process by which living organism have changed
       from the simplest unicellular form to the most complex multi-cellular forms that are existing
       today and on.
      The organic evolution can be defined as the formation of complex organism from simple
       organism over a period of time. The raw materials for evolution are variations.
      Organic evolution primarily involves modifications in the existing organism and the inheritance
       of these modifications.
Homologous Organs
      It is the type of organs which perform different functions in different animals but are structurally
       similar.
      Example – Wings of a bat, the lateral fin of a whale, and the human arm [they all have similar
       bone structure layout, butut they carry out distinct functions] – Homologous structures mean they
       had come from a common ancestor.
Analogous Organs
      It is the type of organs which perform similar function in different animals but are structurally
       different.
       Example – Bats ’wings & Files’ wings they both are used to help the creature fly but they have
        different patterns of bone structure. The similarity of the function also reflects that they are
        adapted to similar environment.
Vestigial Structures
       Vestigial structures are parts of an animal’s body that currently serve no purpose. In the species’
        evolutionary past they served a function, but now are only relics.
       For example, many whales have a hop bone. This is useless in their aquatic environment now,
        but millions of years ago their ancestors had legs and walked on land.
       There are 90 vestigial organs in human body. The appendix, coccyx, muscles that ears, muscles
        that make hair raise up, little toe, wisdom teeth, and body hair are probably the most widely
        known vestigial human organ. The formation of goose bumps in human under stress is a
        vestigial reflex.
       Also, humans have a tail bone, which is a few fused vertebrae at the end of our spine.
Connecting Links
       The organism having the structures of two different groups are called connecting links.
       These explain the path of evolution.
       There are several theories that try to explain the mechanism of organic evolution.
                              Theories of Evolution
Lamarckism
Darwinism
      The theory of natural selection was put forth by Charles Darwin in his book ‘On the Origin of
       Species by Means of Natural Selection’, co-authored
                                                   co           by Alfred Russel Wallace.
      According to Darwin, nature has its own ways of selecting the best from the availabl
                                                                                       available species for
       continuation of life. The mechanism of natural selection works as follows:
      Individuals of a species produce more offspring than necessary to replace themselves.
      This results in competition and struggle for existence among the individuals. Wit
                                                                                       Within the species
       itself, there are variations that result
                                         r      in minor differences amongg the individuals.
      Thus, in the struggle for existence only the ones with the variations best adapted to their
       environment survival of the fittest”.
      Mutation theory proposed by Hugo DeVries attempts to find the sources of variations in
       mutation occurring in individual organism.
Neo-Darwinism
      Neo-Darwinism is the modern theory on organic evolution that combines the ideas of
       Darwinism and mutation theory.
      Neo-Darwinism attempts to explain evolution in terms of genotypic variations, natural selection
       and isolation.
   The study of extinct organisms ( palaeontology) provides direct evidences in favour of evolution.
   Indirect evidences are available from the branches like morphysiology abd so on by a
    comparative study of extint organism.
   Variations: The differences that occur in the characteristics between members of the same
    species, form the raw materials for evolution.
   Variations can be stomach or blastogenic. Somatic variations are non-heritable, while
    blastogenic variations are heritable.
   Mutations: Recombinations, genetic drift, natural selection and migration are the main sources
    of variation.
   Origin of a new species from the existing one is called speciation. Speciation can be
    multiplicative involving splitting of one species into two or more or phyletic involving
    replacement of one species by another.
   Instant speciation may occur due to hybridization and polyploidy.
   Isolation is the separation of population by certain barriers, which prevent interbreeding.
   Isolation may occur due to geographical barriers such as land masses, mountains and rivers.
   Isolation may also be reproductive isolation. It may involve preventing of mating (pre-
    reproductive) or mechanism that operate after mating (post-reproductive).
                         Classification of Animals
Phylum-Protozoa
Phylum-Porifera
      Cnidarians bodies typically take one of two forms: the polyp or the medusa. While the polyp
       form is adapted for a sedentary or sessile lifestylem, the medusa from is adapted for floating or
       free-swimming.
      Examples: This phylum consists of the jellyfish, hydra, sea anemones, corals, sea pens, sea
       wasps, and box jellyfish.
Phylum – Platyhelminthes
      Most members of this phylum are parasitic (fluckes and tapeworms), but some are free living
       (e.g., planaria). There are about 20,000 species.
      Platyhelminthes are hermaphroditic, and the parasitic species often have very complex
       reproductive (life) cycles.
      Examples: Tapeworms, Flukes, Turbellaria
      Phylum Aschelminthes (Nematoda/Round worm)
      Free living nematodes are found in the sea, freshwater or in the soil in all kinds of environment.
      There are also many parasitic nematodes found in all groups of plants and animals.
      Body is long, cylindrical, fusiform (pointed at both the ends).
      The Saprophagous species live in decomposing plant and animal bodies and in rotting fruits.
      Examples : Ascaris (Round worms), Hookworms and Thread worms, etc.
Phylum – Annelida
Phylum – Arthropoda
      This phylum is the largest in the animal kingdom comprising of more than 75 % of the animal
       species that has been identified.
      Arthropodas present three distinguishing features: they are metameric being (segmented body),
       they have an exoskeleton made of chitin and they present articulated limbs.
      The body feature from which the phylum takes its name is the jointed appendages, which
       include antennae and mouthparts as well as walking legs.
      The circulatory system is open and consists of a heart, arteries, and the open spaces of the
       hemocoel.
      A cockroach has a single heart and thirteen chambers.
      Examples: Ants, files, cockroaches, shrimps, crabs, spiders and scorpions.
Phylum – Mollusca
Phylum – Echinodermata
Phylum – Chordata
      Presences of a solid supporting structure on the dorsal side of the body called notochord.
      Presence of a dorsal hollow, tubular nerve cord.
      Presence of pharyngeal gill slits at least in the embryonic stages.
                                             Botany
                                       Branches of Botany
      Botany is the branch of biology that deals with plants. It involves the study of the structure,
       properties, and biochemical processes of all forms of plant life, including trees.
      Today, the principal branches of botanical study are morophology, physiology, ecology, and
       systematic (the identification and ranking of all plants).
      Various subdisciplines include brylogy (the study of mosses and liverworsts), pteridology (the
       study of ferns and their relatives), paleobotany (the study of fossil plants), and palynology (the
       study of modern and fossil pollen and spores).
      In 1883, A.W. Eichler gave a system of classification for the whole plant kingdom. He classified
       the plant kingdom into sub-kingdoms. They are Coyptogams and Phanerogames.
The cryptogams
      The Cryptograms are flowerless and seedless plants. They are simple plants like algae, mosses
       and ferns while do not produce flowers, fruits and seeds. Crypotogams are considered as lower
       plants.
      Algae are chlorophyll-bearing thallophytes. They, are mostly aquatic occurring in freshwater and
       in sea. They exhibit autotrophic mode of nutrition.
      Bryophytes are the simplest land plants with undifferentiated plant body. They are adapted to
       grow in water and on land.
      Pteridophyta are most advanced cryptogams. Vasucular tissues are present in the plant body.
       Therefore, pteridophytes are also called vascular cryptogams.
Phanerogams
      Plant morphology or phytomor-phology is the study of the physical form and external structure
       of plants. This is usually considered distinct from plant anatomy, which is the study of the
       internal structure of plants, especially at the microscopic level.
The Root
      The root is underground part of the plant and develops from elongation of radical of the
       embryo.
      It is non-green, positive geotropic and negative phototropic.
      Root provides stability, stores nutrients, and acts as the primary source of water and nutrient
       acquisition.
      Two kinds of root systems can be distinguished in flowering plants: tap root system and
       adventitious root system. Usually, dicotyledons possess tap root system and monocotyledons
       adventitious root system.
      Modifications of Root: Roots are modified for support, storage of food, respiration.
      For support: Prop roots in banyan tree, stilt roots in maize and sugarcane.
      Forrespiration: Pneumatophores in Rhizophora (Mangrove).
      For storage of food: Fusiform (radish), Napiform (turnip), Conical (carrot).
The Stem
      Stem is the aerial part of the plant and develops from plumule of the embryo. It bears nodes
       and internodes.
      It is negatively geotropic and positively phototropic.
      Modification of Stem: In some plants, the terms are modified to perform the function of storage
       of food, support, protection and vegetative propagation.
      For Food Storage: Rhizome (ginger), Tuber (potato), Bulb (onion), Corm (colocasia).
       For Support: Stem tendrils of watermelon, grapevine, cucumber.
      For Protection: Auxillary buds of stem of citrus, Bougainvillea get modified into pointed thorns.
       They protect the plants from animals.
      For Vegetative Propagation: Underground steam of grass, strawberry, lateral branches of mint
       and jasmine.
      For Assimilation of Food: Flattened stem of Opuntia contains chlorophyll and performs photo-
       synthesis.
The Leaf
       Develops from shoot apical meristem, flattened, green structure, manufactures the food by
        photosynthesis. It has bud in axil. A typical leaf has leaf base, petiole and lamina.
       A leaf has three main parts – Leaf base, petiole and leaf lamina. In addition, it may process two
        laterial outgrowths of the leaf base, called stipules.
       Venation: The arrangement of veins and veinlets in the lamina of leaf.
       Modifications of Leaves
       Tendrils: (Climbing) – Sweet wild pea
       Spines: (Protection) – Aloe, Opuntia, Argemone
       Pitcher: (Nutrition) – Nepenthes
       Hook: (Support) – Cat’s nail
       Inflorescence: The arrangement of flowers on the floral axis.
The Flower
The fruit
       The mature ripened ovary develops into fruit. The parthenocarpic fruits are formed
                                                                                    formed from ovary
        without fertilsation.
Fruits are many types
The seed
   
      Photo’ refers to light and ‘synthesis’ means preparation. Thus, photosynthesis is the process by
       which the green plants use light energy of the Sun to synthesise carbohydrates. Carbohydrates
       like the simple sugar (glucose) can be stored as starch.
      The green plants synthesise food by photosynthesis. Thus, photosynthesis is the most important
       life sustaining process of nature.
      Photosynthesis is a series of biochemical reaction which can be essentially summarized as
       follows:
      Thus, photosynthesis can be defined as a process which utlises carbon dioxide and water in the
       presence of sunlight and chlorophyll to synthesise carbohydrates like glucose.
                                            Genetics
       Genetics deals with the inheritance as well as the variation of characters from parents to
        offspring.
       Inheritance is the process by which characters are passed on from parent to progeny.
       Variation is the degree by which progeny differ from their parents.
       William Bateson was the first person to use the term “genetics” to describe the study of
        heredity and biological inheritance and the chief populariser of the ideas of Gregor Mendel
        following their rediscovery in 1900 by Hugo de Vries and Carl Correns. Thomas Sutton in 1902
        proposed that genes are located on chromosomes.
       Gregor Mendal conducted hybridization experiments on “garden peas” for seven years (1856-
        1863) and proposed “laws of inheritance”.
       Mendel proposed that something was being stably passed down, unchanged, from parent to
        offspring through the gametes, over successive generations. He called these things as ‘factors’.
       Now-a-days, we call them as genes.
       Genes therefore are the units of inheritance.
       Genes which code of a pair of contrasting traits are known as alleles, i.e. they are slightly
        different forms of the same gene.
Law of Dominance
Law of Segregation
       The alleles do not show any blending and that both the characters are recovered as such in the
        F2 generation though one of these is not seen at the F1 stage.
       The parents contain two alleles during gamete formation; the factors or alleles of a pair
        segregate or separate from each other such that a gamete receive only one of the two factors.
       Homozygous parent products all gametes that are similar i.e contain same type of allele.
      Heterozygous parent produces two kinds of gametes each having one allele with equal
       proportion.
Law of recombination
      Two characters determined by two unlinked genes are recombined at random in gametic
       formation, so that they segregate independently of each other, according to the first law.
Techniques of Biotechnology
      Biotechnology deals with techniques of using live organism or enzymes from organism to
       produce products and processes useful to humans.
      Two Core Techniques that enabled birth of modern biotechnology:
      Genetic Engineering: Techniques to alter the chemistry of genetic material (DNA and RNA). The
       techniques of genetic engineering includes creation of recombinant DNA, use of gene cloning
       and gene transfer.
      Maintenance of Sterile: (microbial contamination-free) ambient chemical engineering processes
       to enable growth of only the desired microbe/eukaryotic cell in large quantities.
Gene Therapy
   Gene therapy is the insertion of genes into an individual’s cells and tissues to treat diseases
    especially hereditary diseases. It does so by replacing a defective mutant allele with a functional
    one or gene targeting which involves gene amplification. Viruses that attack their genetic
    material into the hosts and introduce their genetic material into the host cell as part of their
    replication cycle are used as vectors to transfer healthy genes or more recent portions of genes.
   Recombinant DNA technology has made it possible to engineer microbes, plants and animals
    such that they have novel capabilities. Since the recombinant therapeutics are identical to
    human proteins, they do not introduce unwanted immunological responses and are free from
    risk of infection as was observed in case of similar products isolated from non-human sources.
    Human insulin is made in bacteria, yet its structure is absolutely identical to that of the natural
    molecule.
   Genetically Modified Organism have been created by using methods other than natural
    methods to transfer one or more genes from one organism to other, generally using techniques
    such as Recombinant DNA technology.
   Animals that have had their DNA manipulated to prossess and express an extra (foreign) gene
    are known as transgenic animals.
   GM plants have been useful in increasing crop yields, reduce post-harvest losses and make crops
    more tolerant of stress.
   Recombinant DNA technology has made it possible to engineer microbes, plants and animals
    such that they have novel capabilities. Since the recombinant therapeutics are identical to
    human proteins, they do not introduce unwanted immunological responses and are free from
    risk of infection as was observed in case of similar products isolated from non-human sources.
    Human insulin is made in bacteria, yet its structure is absolutely identical to that of the natural
    molecule.
   Genetically Modified Organism have been created by using methods other than natural
    methods to transfer one or more genes from one organism to other, generally using techniques
    such as Recombinant DNA technology.
   Animals that have had their DNA manipulated to prossess and express an extra (foreign) gene
    are known as transgenic animals.
   Bt Toxin is produced by a bacterium called Bacillus thuringiensis (Bt for short). Bt toxin gene has
    been expressed in plants to provide resistance to insects without the need for insecticides; in
          effect created a bio-pesticide. Examples are Bt cotton, Bt corn, rice, tomato, potato and
          soyabean, etc.
Cloning
         Cloning is the process by which an entire organism is reproduced from a single cell taken from
          the parent organism and in a genetically identical manner.
         This means the cloned animal is an exact copy in every way of its parent.
         Molecular Cloning: Molecular cloning focuses on making identical copies of DNA molecules. This
          type of cloning is also called as reproductive cloning.
         Therapeutic Cloning: Therapeutic cloning involves the cloning of human embryos for the
          production of stem cells. The embryos are eventually destroyed in this process.
         Dolly was a female domestic sheep and the first mammal to be cloned from an adult somatic
          cell, using the process of nuclear transfer. She was cloned by Ian Wilmut, Keith Campbell and
          their colleagues.
         Noori is a female pashmina goat, the first pashmina goat to be cloned using the process of
          nuclear transfer. Shah and six other scientists at Sher-i-Kashmir University took two years to
          clone Noori, using the relatively new ‘handmade’ cloning technique involving only a microscope
          and a steady hand.
         The technique of in-vitro fertilization and in-vitro development followed by the embryo transfer
          in the uterus of the normal female to start the development and finally leading to normal birth
          is called test tube baby.
   It is basically conceived by artificial insemination.
   Methodology involves the following steps:
   Removal of unfertilized ovum from reproductive tract of a female.
   Ovum is kept under aseptic conditions.
   Fusion of sperm and ovum in a culture medium, outside the female body to form the zygote.
   Zygote is stimulated to develop in vitro p to 32-celled stage.
   Developing embryo is implanted on the endometrium of the uterus at 32-celled stage. So, the
    pregnancy in the woman starts and further the development of the child continues in the womb
    till it is born.
   Methodology involves the following steps:
   Removal of unfertilized ovum from reproductive tract of a female.
   Ovum is kept under aseptic conditions.
   Fusion of sperm and ovum in a culture medium, outside the female body to form the zygote.
   Zygote is stimulated to develop in vitro p to 32-celled stage.
   Developing embryo is implanted on the endometrium of the uterus at 32-celled stage. So, the
    pregnancy in the woman starts and further the development of the child continues in the womb
    till it is born.
   The world’s first test tube baby (a baby girl) named as Louise Joy Brown was born on July 25,
    1978 in Great Britain.
   India’s first test tube baby was born in Kolkata on October 3rd, 1978. Her name is Durga.
               Agriculture and Animal Husbandry
Agriculture
Animal Husbandry
      Animal husbandry is the agricultural practice of breeding and raising livestock by applying
       scientific methods.
      Animal husbandry includes domestication of animals to obtain animal products like milk, meat,
       wool, skin and hyde etc. and to use them for draught and transportation.
      India has about 20 per cent of the world’s cattle population.
      Cattle population in India belongs to three: breeds These include: (i) milich breed, (ii) draught
       breed, and (iii) mixed or general breed.
      At last, due to ecological imbalance, climate change, global warming and green house effect
       affect the physical pattern which needs to be dealt very cautiously in order to feed the people.