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Fusidic Acid

Fusidic acid is a bacteriostatic antibiotic that works by inhibiting bacterial protein synthesis. It is effective against gram-positive bacteria like Staphylococcus and Streptococcus. It is available as tablets dosed three times daily for adults and as a cream or ointment applied three to four times daily. Common side effects include local allergic reactions at the application site. It is used to treat bacterial skin infections and conjunctivitis. It should not be taken with quinolones and may have additive effects when used with rifampicin.

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45 views2 pages

Fusidic Acid

Fusidic acid is a bacteriostatic antibiotic that works by inhibiting bacterial protein synthesis. It is effective against gram-positive bacteria like Staphylococcus and Streptococcus. It is available as tablets dosed three times daily for adults and as a cream or ointment applied three to four times daily. Common side effects include local allergic reactions at the application site. It is used to treat bacterial skin infections and conjunctivitis. It should not be taken with quinolones and may have additive effects when used with rifampicin.

Uploaded by

siri
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© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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FUSIDIC ACID

CLASS : ANTIBIOTIC

MECHANISM :Fusidic acid acts as a bacterial protein synthesis inhibitor by


preventing the turnover of elongation factorG (EF-G) from the ribosome. Fusidic acid is
effective primarily on Gram-
positive bacteriasuchas species, Streptococcus species,[2] and Corynebacteriumspecies.
Fusidic acid inhibits bacterial translation and does not kill the bacteria, and is therefore
termed "bacteriostatic.

DOSES AVAILABLE:

 Adults—500 mg (2 tablets) three times daily

Osteomyelitis (bone and joint infections) or skin and soft tissue infections:

 Adults—15 milliliters three times daily


 Children—Up to 1 year of age: 1 milliliter (mL) per kilogram DAILY divided
into 3 equal doses; 1 to 5 years of age is 5 mL three times daily; 6 to 12 years
of age is 10 mL three times daily.

MAJOR ADR :allergic reaction at the site of application, including redness, swelling,
rash, and/or itching

 mild irritation at area of application

 pain (only when medication is applied to deep leg ulcers)

INDICATIONS : Its used to bacterial infections ,such as skin infections ( including


cellulitis and impetigo) and eye infections (including conjunctivitis,also known as red
eye)
DRUG INTERACTIONS :

Fusidic acid should not be used with quinolones, with which they are antagonistic. When
combined with rifampicin, the action of fusidic acid is additive or synergistic.

HOW TO USE, WHEN TO USE: Its usual to put on fusidic acid cream or
ointment 3 or 4times a day .

CONTRA INDICATIONS : Fusidic acidcream,ointment or eye drops take them at


the same time to cause problems.

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