Nutrition
Dr.M.Manivasagam, Professor
Rajah Muthiah Medical College & Hospital
         Annamalai University
                      Nutrition
•   The process by which the organism utilizes food
•   National nutrition week – 1st – 7th Sept
•   Energy – Carbohydrates and Fats
•   Body building – Protein
•   Protective foods – Vitamins & Minerals
                              Energy
• Food – Supplies energy for physical activity and metabolic
  needs
• Nutrients – for maintaining growth and repair or worn out /
  ageing tissues
• Calories – heat required to raise the temperature of 1 gm of
  water from 14.5 to 15.5 C
• Caloric requirement –
   –   1 – 10 kg – 100 kcal / kg / day
   –   11 – 20 kg – 1000 + 50 kcal / kg / day
   –   > 20 kg – 1500 + 20 kcal / kg / day
   –   Simple formula – till one year 1000 kcal, add 100 kcal for every
       year from then.
                     Carbohydrates
• Provide energy, taste, preserve foods
• Types
   – Monosaccharides – glucose
   – Disaccharides – sucrose
   – Polysaccharides – glycogen
• Glucose
   – Fuel for brain and muscle
   – Converted to glycogen, stored in liver and muscles
• 55 – 60% of total calories
                            Fiber
• Constituent of plant cell wall
• Contribute to the bulk and very little to the energy of food
• Includes cellulose, pectins, gums, lignins
• Water holding capacity, bile binding capacity, growth of
  normal intestine microflora
• Lowers cholesterol and limit glucose absorption
• Softening of stools and acceleration of intestinal time
• High fiber can cause reduced bioavailability of minerals,
  flatulency and decreased appetite
                        Protein
•   Second most abundant substance in body
•   24 amino acid, 8 essential AA
•   Helps the child to grow and formation of body fluids
•   Requirement – 1.5 gm / kg / day
•   Complete protein – contain all the Essential AA
•   Reference protein : provides amino acid pattern
    close to tissue protein - EGG
                                      Fat
•   Concentrated source of energy
•   Triglycerides (fats & oils) phospholipids (lecithin), sterols (cholesterol)
•   Saturated FA – Animal source except coconut oil
•   Unsaturated FA – Essential FA
•   Visible and non visible fats
•   Omega 6 FA
     – Linoleic / Arachidonic acid
     – Defi – skin changes
• Omega 6 FA
     – Linolenic / Eicosapentanoic acid
     – Defi – neurological and visual symptoms
                           Minerals
• Small inorganic elements
• Calcium, Phosphorous, Sodium, Chloride, Magnesium,
• Trace elements
   – Essential – iron, iodine, zinc, selenium, copper, molybdenum
   – Probably essential – manganese, silicon, nickel, boron
   – Potentially toxic – fluorine, lead, cadmium, mercury, arsenic
                       Periods of growth
• Prenatal period
   – Ovum – 0 – 14 days
   – Embryo – 14 days to 9 weeks
   – Fetus – 9 weeks to birth
• Perinatal period
   – 22 weeks to 7 days after birth
• Postnatal period
   –   Newborn first 4 weeks after birth
   –   Infancy – first year
   –   Toddler – 1 – 3 year
   –   Preschool – 3 – 5 years
   –   School child – 6 – 10 years (girls), 6 – 12 years (boys)
        Periods of growth – contd..
• Adolescence
  – Early Adolescence : 10 – 13 years
  – Middle Adolescence : 14 – 16 years
  – Late Adolescence : 17 – 20 year
            Assessment of Growth
•   Anthropometry
•   Assessment of Tissue growth
•   Bone age
•   Dental Age
•   Biochemical & Histological
         Parameters – age dependent
•   Weight
•   Length / height
•   Head circumference
•   Chest circumference
•   Mid arm circumference
•   Skin fold thickness
•   Upper segment – lower segment ratio
•   Arm span
•   Mid parental height
       Parameters – age independent
•   Bangle test
•   Shakir’s tape
•   Quack stick
•   Body mass index
•   Ponderal index
               Low birth weight
• Low Birth weight - < 2500 gms
• Very LBW - < 1500 gms
• Extremely LBW - < 1000 gms
Classification for weight – GOMEZ
Wt / age in %      Grade of malnutrition
    >90                  Normal
  76 – 90                    I
  61 – 75                   II
    <60                     III
 Classification for weight – WELCOME
                  TRUST
60-80%    Edema +       Kwarshiorkor
60-80%    -             Under wt
<60       -             Marasmus
<60       Edema +       m.k
Classification for weight - IAP
    >80%         Normal
    71-80%       Grade I
    61-70%       Grade II
    51-60%       Grade III
    <50%         Grade IV
         Classification of PEM by Height
ht/age                water low   mc laren   v.rao
Normal                >95         >93        >90
Iostunting / short    90-95       80-93      80-90
IIo stunting          85-90       -          -
IIIo stunting/dwarf   <85         <80        <80
         Classification – Contd..
Wt/ht                Water low   Mc laren
Normal               >90         >90
IO mild (wasting)    80-90       85-90
IIo mod (wasting)    70-80       75-85
IIIo sev (wasting)   <70         <75
                Weight for Height
• Acute malnutrition :
   – Height for age is normal
   – Weight for age is low
• Chronic Malnutrition :
   – Height for age and weight for age are low
       Bone age / Skeletal Maturity
• Appearance & Fusion of Various Epiphyseal centres
• Radiological examination of Wrist and elbow
           Primary Dentition
                   Eruption Sequence
Central Incisors                       6 – 7 months
Lateral Incisors                       8 – 9 months
Canine                                 16 – 18 months
First molar                         12 – 14 months
Second molar                        20 – 24 months
            Completion of enamel formation
Central Incisors                       1 ½ months
Lateral Incisors                       2 ½ months
Canine                                 9 months
First molar                            6 months
Second molar                           11 months
Permanent Dentition – Eruption Sequence
         Central Incisors    7 – 8 years
         Lateral Incisors    8 – 9 years
             Canine         11 – 12 years
         First Premolar     10 – 11 years
        Second Premolar     10 – 12 years
           First molar       6 – 7 years
         Second molar       12 – 13 years
           Third molor       17 years +
Permanent Dentition – Completion of
        Enamel formation
       Central Incisors     4 – 5 years
       Lateral Incisors     4 – 5 years
           Canine           6 – 7 years
       First Premolar       5 – 6 years
      Second Premolar       6 – 7 years
         First molar      2 ½ - 3 ½ years
       Second molar         7 – 8 years
           Protein Energy Malnutrition
• PEM is a range of pathological conditions arising from lack
  on varying proportions of protein and calories, more
  frequently in infants and young children commonly
  associated with infections
• Spectrum of PEM
   –   Kwashiorkar
   –   Marasmus
   –   Marasmic Kwashiorkar
   –   Prekwashiorkar
   –   Nutritional dwarfism
   –   Underweight
   –   Invisible PEM
                 Kwashiorkar
• Disease of first child when the second child has
  displaced the 1st one from the breast
• Classical features – Apathy, Miserable, stunted
  growth, edema, hepatomegaly, tremors, hair & Skin
  changes
                       Marasmus
• Active, alert, good appetite, later becomes irritable
• Wasting – child becomes skin and bone
   –   Grade I – axilla and groin
   –   Grade II – Buttocks & thigh
   –   Grade III – Chest & Abdomen
   –   Grade IV – Buccal pad of fat
                          Others
• Marasmic Kwashiorkar – Marasmic child develops edema
• Prekwashiorkar – Poor nutritional status with some features
  of Kwashiorkor but no edema
• Nutritional dwarfism – prolonged PEM starting early in life –
  remain for number of year
• Underweight - Malnourished child with no features of
  kwashiorkor or marasmus
• Invisible PEM – 6 – 24 months, looks normal, too small for
  age and poor resistance to infection
                   Etiology of PEM
• Conditioning influences – LBW / Infections
• Cultural practices – Food fads / method of cooking /
  Alcoholism
• Socio economic factors – poverty / Illiteracy / lack of
  knowledge regarding nutritional value of food
• Food production & intake
   – abrupt withdrawal of breast milk
   – Delayed and inadequate weaning
   – Lack of food supplementation for target group
             Etiology of PEM – Contd..
• Availability and utilization of health / other services
   –   Lack of health education
   –   Nutritional surveillance
   –   Nutritional rehabilitation
   –   Primary health care
   –   Immunization
   –   Early diagnosis
   –   Prompt treatment
   –   Referral services
                Clinical feature of PEM
•   Growth retardation – Weight loss, wasting, stunting
•   Hepatomegaly – fatty infiltration
•   Hair changes – Flag sign
•   Skin changes – Flaky paint dermatoses
•   Mucosal changes – Vitamin deficiencies, bacterial infections
•   Bleeding / purpuric changes
•   Edema – moon face, effusion into serous cavities
•   Mental changes – irritability and apathy
•   Tremors – seen during treatment
                Clinical signs
• Decreased protein – Kwashiorkor
• Decreased calories – Marasmus
• Acute – Marasmus
• Chronic – Kwashiorkor
• Adaptation – Marasums
• Dysadaptation – Kwashiorkor
               Management of PEM
• Assessment – History, Anthropometry
• Classification – Wellcome trust and IAP
• Investigation
   –   Sr.Albumin
   –   Urinary urea & Creatinine
   –   Urinary Hydroxyproline
   –   Sr. essential amino acid index
   –   Peripheral smear
   –   Liver biopsy
       Management of Acute emergency
•   Hypothermia
•   Hypoglycemia
•   Specific infection
•   Dehydration & electrolyte disturbances
•   Chronic renal failure
•   Anemia
•   Vitamin & Mineral supplements
       Restoration / Nutritional Management
•   ORS → Milk → Family pot feeding
•   High energy milk
•   Cereal milk
•   150 – 200 calories / kg / day
•   3 – 4 gms / kg / day
      Diff b/n Marasmus & Kwashiorkor
                          Marasmus                    Kwashiorkor
      Age                       <1                          1–3
     Edema                     None               Lower legs or generalized
     Wasting               Gross loss of                   Hidden
                     subcutaneous fat, skin and
                              bone
 Muscle wasting              Obvious                       Hidden
Growth retardation           Obvious                      Obvious
 Mental change                 Quite                 Irritable, moaning,
                                                           apathetic
     Appetite                  Good                         Poor
    Diarrhea                  Present                     present
          Diff b/n Marasmus & Kwashiorkor
                               Marasmus                    Kwashiorkor
      Hair change                  Seldom          Often diffuse depigmentation occasional
                                                      flanky paint or enamel dermatosis
       Sr. Albumin             Usually Normal                      Low
   Urinary Urea / gm           Usually Normal                      Low
       creatinine
Urinary Hydroxyproline / gm         Low                            Low
         Creatinine
Sr. Essential amino acid            Low                            Low
         Anemia                  Uncommon                       Common
       Liver biopsy           Normal or atrophic             Fatty changes
             Poor prognosis in PEM
•   Age <6 month – 12 months
•   Deficit in Wt / Ht > 30%, Wt/ age > 40%
•   Stupor or coma
•   Severe infection
•   Petechiae / hemorrhagic tendencies
•   Signs of CCF / resp. difficulty
•   Total serum protein < 3 gm / dl, Sr.Albumin < 2gm%
•   Severe anemia with clinical signs of hypoxia
•   Increased serum bilirubin level, increased transaminase levels
•   Extensive exudative or exfolliative cutaneous lesions
•   Hypoglycemia /hypothermia
•   In serum protein electrophoresis low gamma globulin fraction
•   Low Sr. phospholipids and total lipids
                   Food Values
•   1 cup – 100 ml or 100 gms
•   1 teas spoon – 5 ml or 5 gm
•   1 table spoon – 15 ml or 15 gm (3 teas spoon)
•   1 tumbler – 200 ml (2 cup)
 Food item          Protein gms   Kilocalories
  Iddy – one             2             50
  Puri – two             2             50
Wheat chappati 1         2             50
 Bread slice 1           2             50
    Dosai                2             50
 Uppma 1 cup             6            250
  Ragi 6 tsp             2            100
Cooked dhal 1 tsp       0.5            15
 Bengal gram             1             18
 powder 1 tsp
Cane sugar 1 tsp         0            20
   Food item               Protein gms   Kilocalories
 Brown sugar 1 tsp             0              15
   Honey 1 tsp                 0              15
    Rasam 1 cup                0              20
  Coconut water 1 cup         1.4             24
  Coffee 100 ml               1.4             60
 Butter milk 100 ml           0.8             15
  Butter 100 gm                 -            729
    Ragi 100 gm               7.3            328
Rice 100 gm (Par boiled)      6.4            346
   Wheat 100 gm               11.8           346
   Food item              Protein gms   Kilocalories
 Wheat bread 100 gm          7.8            245
Bengal gram roasted 100      22.5           369
          gm
Black gram Dhal 100 gm        24            347
Green gram dhal 100 gm       24.5           348
 Red gram dhal 100 gm        22.3           335
    Tomato 100 gm            1.4             21
    Egg Hen 1                  6              8
       Biscut 1              0.5             25
    Papadam 1                0.5             25
      Banana 1               0.6             50
 Food item             Protein gms   Kilocalories
Spinach 100 gm              2             26
Cow’s milk 200 ml           6            120
  Curd 30 ml                1             20
Papaya ripe 100 gm         0.6            32
Ground nut 100 seeds
                            9            200
                  6 gms of Protein
•   1 egg                 •   1 ounce (30 ml) meat / fish
•   2 cup milk            •   50 groundnuts
•   3 idlis               •   15 cashewnuts
•   3 chappatis           •   3 cup cooked rice
•   3 dosas               •   6 tsp bengal gram
•   6 puris
•   12 tsp cooked dal
•   18 tsp ragi
Thank you