Preoperative Testing
eAppendix A. Guideline Summary for Preoperative ECG
  Guideline                Summary of recommendations
  American College         ECG is recommended for:
   of Cardiology/            Patients with known heart disease, peripheral vascular disease, or cerebrovascular
   American Heart              disease who are undergoing intermediate- or high-risk surgery
   Association,
                             Patients with one or more clinical risk factors (e.g., coronary artery disease, history
   2007A1
                               of congestive heart failure, cerebrovascular disease, diabetes mellitus, renal
                               insufficiency) who are undergoing vascular surgery
                           ECG is reasonable for:
                             Patients with no clinical risk factors who are undergoing vascular surgery
                             Patients with one or more clinical risk factors who are undergoing intermediate-risk
                               surgery
                           ECG is not indicated for asymptomatic patients undergoing low-risk surgery
  American Society of      ECG may be indicated for patients with cardiovascular risk factors
   Anesthesiologists,
   2002A2
  European Society         ECG is recommended for patients with risk factors who are undergoing intermediate-
    of Cardiology           or high-risk surgery
    and European           ECG may be considered for:
    Society of
                             Patients with risk factors who are undergoing low-risk surgery
    Anaesthesiology,
    2009A3                   Patients with no risk factors who are undergoing intermediate-risk surgery
                           ECG is not indicated for patients with no risk factors who are undergoing low-risk
                            surgery
  Institute for            ECG is recommended for patients older than 65 years
    Clinical Systems       Consider ECG for:
    Improvement,
                             Patients of any age with diabetes, hypertension, chest pain, congestive heart
    2012A4
                               failure, smoking history, peripheral vascular disease, inability to exercise, or
                               morbid obesity
                             Patients with new signs or symptoms of cardiovascular disease
                           ECG is not recommended for asymptomatic patients undergoing low-risk surgery
                            unless medical assessment reveals a high-risk patient
                                                                                                           continued
  ASA = American Society of Anesthesiologists; ECG = electrocardiography.
  *—ASA patient classifications: 1 = healthy patient; 2 = patient with mild systemic disease; 3 = patient with severe
  systemic disease.
  †—Surgical grades: 2 = intermediate; 3 = major; 4 = major+.
March 15, 2013   ◆   Volume 87, Number 6                         www.aafp.org/afp                                       American Family Physician
Preoperative Testing
                            eAppendix A. Guideline Summary for Preoperative ECG (continued)
                            Guideline                 Summary of recommendations
                            UK National               ECG is recommended for:
                             Institute                  Patients of any age who are undergoing cardiovascular surgery
                             for Clinical
                                                        ASA class 1 patients* older than 80 years
                             Excellence, 2003A5
                                                        ASA class 1 patients* older than 60 years who are undergoing grade 3 or 4
                                                         surgery†
                                                        ASA class 2 and 3 patients* with cardiovascular disease
                                                        ASA class 2 patients* older than 60 years with comorbid renal disease who are
                                                         undergoing grade 3 or 4 surgery†
                                                        ASA class 3 patients* older than 40 years with comorbid renal disease who are
                                                         undergoing grade 4 surgery†
                                                        ASA class 2 patients* with comorbid respiratory disease who are older than 80
                                                         years and are undergoing grade 3 or 4 surgery,† or who are older than 60 years
                                                         and are undergoing grade 4 surgery†
                                                        ASA class 3 patients* with comorbid respiratory disease who are older than 60
                                                         years and are undergoing grade 2 or 3 surgery,† or who are older than 40 years
                                                         and are undergoing grade 4 surgery†
                                                      Consider ECG for:
                                                        ASA class 1 patients* older than 16 years who are undergoing neurosurgery
                                                        ASA class 1 patients* older than 40 years who have clinical indications
                                                        ASA class 2 patients* with comorbid respiratory disease who are older than
                                                         40 years, regardless of surgical risk, or who are older than 16 years and are
                                                         undergoing grade 3 or 4 surgery†
                                                        ASA class 3 patients* with comorbid respiratory disease
                                                        ASA class 2 patients* older than 40 years or ASA class 3 patients* of any age with
                                                         comorbid renal disease
                            ASA = American Society of Anesthesiologists; ECG = electrocardiography.
                            *—ASA patient classifications: 1 = healthy patient; 2 = patient with mild systemic disease; 3 = patient with severe
                            systemic disease.
                            †—Surgical grades: 2 = intermediate; 3 = major; 4 = major+.
                            Information from:
                            A1. Fleisher LA, Beckman JA, Brown KA, et al.; American College of Cardiology; American Heart Association Task
                            Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines on Perioperative Cardiovascular Evalu-
                            ation for Noncardiac Surgery); American Society of Echocardiography; American Society of Nuclear Cardiology; Heart
                            Rhythm Society; Society of Cardiovascular Anesthesiologists; Society for Cardiovascular Angiography and Interven-
                            tions; Society for Vascular Medicine and Biology; Society for Vascular Surgery. ACC/AHA 2007 guidelines on periop-
                            erative cardiovascular evaluation and care for noncardiac surgery [published corrections appear in J Am Coll Cardiol.
                            2007;50(17):e242 and J Am Coll Cardiol. 2008;52(9):793-794]. J Am Coll Cardiol. 2007;50(17):e159-e241.
                            A2. American Society of Anesthesiologists Task Force on Preanesthesia Evaluation. Practice advisory for preanesthesia
                            evaluation. Anesthesiology. 2002;96(2):485-496.
                            A3. Poldermans D, Bax JJ, Boersma E, et al.; Task Force for Preoperative Cardiac Risk Assessment and Perioperative Car-
                            diac Management in Non-cardiac Surgery; European Society of Cardiology (ESC). Guidelines for pre-operative cardiac
                            risk assessment and perioperative cardiac management in non-cardiac surgery. Eur Heart J. 2009;30(22):2769-2812.
                            A4. Institute for Clinical Systems Improvement. Health care guideline: preoperative evaluation. 10th ed. Bloomington,
                            Minn.: Institute for Clinical Systems Improvement; 2012.
                            A5. National Institute for Clinical Excellence. Preoperative tests: the use of routine preoperative tests for elective sur-
                            gery. http://www.nice.org.uk/nicemedia/pdf/CG3NICEguideline.pdf. Accessed December 12, 2012.
American Family Physician                                    www.aafp.org/afp	                             Volume 87, Number 6        ◆   March 15, 2013
                                                                                                                         Preoperative Testing
  eAppendix B. Guideline Summary for Preoperative Chest Radiography
  Guideline                  Summary of recommendations
  American College of        Chest radiography may be appropriate for patients previously diagnosed with chronic obstructive pulmonary
   Physicians, 2006B1         disease or asthma
  American College of        Chest radiography is usually appropriate for:
   Radiology, 2008B2           Patients with acute cardiopulmonary findings on history or physical examination
                               Patients older than 70 years who have chronic cardiopulmonary disease and have not had chest radiography in
                                 the previous six months
  American Society of        Consider chest radiography for:
   Anesthesiologists,          Patients who smoke
   2002B3
                               Patients with a history of recent upper respiratory infection
                               Patients with chronic obstructive pulmonary disease
                               Patients with cardiac disease
                             However, if these conditions are chronic and stable, preoperative chest radiography is not necessarily indicated
  Institute for              Chest radiography may be considered for patients with signs or symptoms suggesting new or unstable
    Clinical Systems          cardiopulmonary disease
    Improvement,
    2012B4
  UK National Institute      Chest radiography is recommended for:
   for Clinical                Patients of any age who are undergoing cardiovascular surgery
   Excellence, 2003B5
                               ASA class 2 patients* with cardiovascular disease who are undergoing grade 4 surgery†
                               ASA class 3 patients* with cardiovascular disease who are undergoing grade 2, 3, or 4 surgery†
                               ASA class 3 patients* with respiratory disease
                             Consider chest radiography for:
                               ASA class 1 patients* older than 60 years who are undergoing grade 4 surgery† or neurosurgery
                               ASA class 2 patients* with respiratory disease who have a change in symptoms or might need ventilator support
                               ASA class 2 patients* with cardiovascular disease
                               ASA class 3 patients* with cardiovascular disease or respiratory disease
                               ASA class 2 or 3 patients* with renal disease who are undergoing grade 3 or 4 surgery,† or who are older than
                                60 years and are undergoing any surgery
  ASA = American Society of Anesthesiologists.
  *—ASA patient classifications: 1 = healthy patient; 2 = patient with mild systemic disease; 3 = patient with severe systemic disease.
  †—Surgical grades: 2 = intermediate; 3 = major; 4 = major+.
  Information from:
  B1. Qaseem A, Snow V, Fitterman N, et al.; Clinical Efficacy Assessment Subcommittee of the American College of Physicians. Risk assessment for and
  strategies to reduce perioperative pulmonary complications for patients undergoing noncardiothoracic surgery. Ann Intern Med. 2006;144(8):575-580.
  B2. American College of Radiology. ACR Appropriateness Criteria: routine admission and preoperative chest radiography. http://www.acr.org/~/
  media/ACR/Documents/AppCriteria/Diagnostic/RoutineAdmissionAndPreoperativeChestRadiography.pdf. Accessed December 12, 2012.
  B3. American Society of Anesthesiologists Task Force on Preanesthesia Evaluation. Practice advisory for preanesthesia evaluation. Anesthesiology.
  2002;96(2):485-496.
  B4. Institute for Clinical Systems Improvement. Health care guideline: preoperative evaluation. 10th ed. Bloomington, Minn.: Institute for Clinical
  Systems Improvement; 2012.
  B5. National Institute for Clinical Excellence. Preoperative tests: the use of routine preoperative tests for elective surgery. http://www.nice.org.uk/
  nicemedia/pdf/CG3NICEguideline.pdf. Accessed December 12, 2012.
March 15, 2013   ◆   Volume 87, Number 6                          www.aafp.org/afp                                         American Family Physician
Preoperative Testing
  eAppendix C. Guideline Summary for Preoperative Electrolyte Measurement
  Guideline                Summary of recommendations
  American Society of      Preoperative electrolyte measurement could be considered if:
   Anesthesiologists,        Abnormal results would change perioperative management
   2002C1
                             Patient is at risk of abnormal results based on history and physical examination (e.g., liver or renal disease,
                               use of certain medications)
  Institute for            Electrolyte measurement can be considered for:
    Clinical Systems         Patients taking digoxin
    Improvement,
                             Patients taking diuretics
    2012C2
                             Patients taking angiotensin-converting enzyme inhibitors or angiotensin receptor blockers
  UK National              Electrolyte measurement is recommended for:
   Institute for             All patients with a known renal comorbid condition
   Clinical Excellence,
                             All patients undergoing neurosurgery or cardiovascular surgery
   2003C3
                             All patients older than 40 years who are undergoing grade 4 surgery†
                             ASA class 3 patients* with cardiovascular disease
                             ASA class 2 patients* with cardiovascular disease who are undergoing grade 3 or 4 surgery†
                             ASA class 2 patients* older than 60 years with cardiovascular disease who are undergoing grade 2 surgery†
                             ASA class 2 patients* with comorbid respiratory disease who are undergoing grade 4 surgery†
                             ASA class 2 patients* older than 60 years who have comorbid respiratory disease and are undergoing high-
                              intermediate–risk surgery
                             ASA class 3 patients* with comorbid respiratory disease who are undergoing high-intermediate– or high-risk surgery
                           Electrolyte measurement is not recommended for:
                             ASA class 1 patients* younger than 40 years who are undergoing low-risk surgery
                             ASA class 1 patients* younger than 16 years who are undergoing low-intermediate–risk surgery
                             ASA class 2 patients* with comorbid respiratory disease who are younger than 60 years and are undergoing
                              low-risk surgery, or who are younger than 40 years and are undergoing low-intermediate–risk surgery
  ASA = American Society of Anesthesiologists.
  *—ASA patient classifications: 1 = healthy patient; 2 = patient with mild systemic disease; 3 = patient with severe systemic disease.
  †—Surgical grades: 2 = intermediate; 3 = major; 4 = major+.
  Information from:
  C1. American Society of Anesthesiologists Task Force on Preanesthesia Evaluation. Practice advisory for preanesthesia evaluation. Anesthesiology.
  2002;96(2):485-496.
  C2. Institute for Clinical Systems Improvement. Health care guideline: preoperative evaluation. 10th ed. Bloomington, Minn.: Institute for Clinical
  Systems Improvement; 2012.
  C3. National Institute for Clinical Excellence. Preoperative tests: the use of routine preoperative tests for elective surgery. http://www.nice.org.uk/
  nicemedia/pdf/CG3NICEguideline.pdf. Accessed December 12, 2012.
American Family Physician                                         www.aafp.org/afp	                            Volume 87, Number 6        ◆   March 15, 2013
  eAppendix D. Guideline Summary
  for Preoperative Urinalysis
  Guideline                   Summary of recommendations
  American Society of         Urinalysis is recommended for:
   Anesthesiologists,           Patients with new urinary symptoms
   2002D1
                                Patients undergoing urologic surgery
                                Patients undergoing surgery with implantation of
                                  foreign material
  UK National Institute       Urinalysis is recommended for:
   for Clinical                 Patients with new urinary symptoms
   Excellence, 2003D2
                                Patients undergoing urologic surgery
                              Urinalysis is not recommended for children younger than
                               16 years who are undergoing grade 1 or 2 surgery*
                              For all other patients, the panel could not come to
                                consensus
  *—Surgical grades: 1 = minor; 2 = intermediate.
  Information from:
  D1. American Society of Anesthesiologists Task Force on Preanesthesia Evaluation.
  Practice advisory for preanesthesia evaluation. Anesthesiology. 2002;96(2):485-496.
  D2. National Institute for Clinical Excellence. Preoperative tests: the use of routine
  preoperative tests for elective surgery. http://www.nice.org.uk/nicemedia/pdf/
  CG3NICEguideline.pdf. Accessed December 12, 2012.
  eAppendix E. Guideline Summary for Preoperative
  Glucose Measurement
  Guideline                   Summary of recommendations
  American Society of         Consider random glucose measurement for:
   Anesthesiologists,           Patients with endocrine, renal, or hepatic disorders
   2002E1
                                Patients taking certain medications or alternative
                                  therapies (unspecified)
  UK National Institute       Random glucose measurement is recommended for:
   for Clinical                 Patients older than 16 years who are undergoing
   Excellence, 2003E2             cardiac surgery or neurosurgery
                                Patients taking corticosteroids
                                Patients taking diuretics
                              Random glucose measurement is not recommended for:
                                Asymptomatic patients younger than 16 years
                                Patients with diabetes mellitus who are compliant
                                  with therapy
  Information from:
  E1. American Society of Anesthesiologists Task Force on Preanesthesia Evaluation.
  Practice advisory for preanesthesia evaluation. Anesthesiology. 2002;96(2):485-496.
  E2. National Institute for Clinical Excellence. Preoperative tests: the use of routine pre-
  operative tests for elective surgery. http://www.nice.org.uk/nicemedia/pdf/CG3NICE-
  guideline.pdf. Accessed December 12, 2012.
March 15, 2013   ◆   Volume 87, Number 6                              www.aafp.org/afp         American Family Physician
Preoperative Testing
  eAppendix F. Guideline Summary for Preoperative CBC
  Guideline                     Summary of recommendations
  American Society of           Consider CBC for:
   Anesthesiologists,             Patients with liver disease
   2002F1
                                  Patients at extremes of age
                                  Patients with a history of anemia or bleeding
                                  Patients with other hematologic disorders
                                  Type and invasiveness of the surgical procedure (not specified by the guideline)
  Institute for                 CBC is recommended for:
    Clinical Systems              Patients with a history of anemia
    Improvement, 2012F2
                                  Patients with a history suggestive of recent blood loss
  UK National Institute         CBC is recommended for:
   for Clinical                   Patients undergoing cardiovascular surgery
   Excellence, 2003F3
                                  Patients older than 60 years who are undergoing neurosurgery
                                  ASA class 2 or 3 patients* who have cardiovascular disease and are undergoing
                                   grade 3 or 4 surgery†
                                  ASA class 2 or 3 patients* older than 80 years who have respiratory disease and
                                   are undergoing grade 2 surgery†
                                  ASA class 2 or 3 patients* who have respiratory disease and are undergoing
                                   grade 3 or 4 surgery†
                                  ASA class 2 patients* who have renal disease and are undergoing grade 3 or
                                   4 surgery†
                                  ASA class 3 patients* who have renal disease and are undergoing any type
                                   of surgery
  ASA = American Society of Anesthesiologists; CBC = complete blood count.
  *—ASA patient classifications: 1 = healthy patient; 2 = patient with mild systemic disease; 3 = patient with severe
  systemic disease.
  †—Surgical grades: 2 = intermediate; 3 = major; 4 = major+.
  Information from:
  F1. American Society of Anesthesiologists Task Force on Preanesthesia Evaluation. Practice advisory for preanesthesia
  evaluation. Anesthesiology. 2002;96(2):485-496.
  F2. Institute for Clinical Systems Improvement. Health care guideline: preoperative evaluation. 10th ed. Bloomington,
  Minn.: Institute for Clinical Systems Improvement; 2012.
  F3. National Institute for Clinical Excellence. Preoperative tests: the use of routine preoperative tests for elective sur-
  gery. http://www.nice.org.uk/nicemedia/pdf/CG3NICEguideline.pdf. Accessed December 12, 2012.
American Family Physician                                            www.aafp.org/afp	                             Volume 87, Number 6   ◆   March 15, 2013
                                                                                                                         Preoperative Testing
  eAppendix G. Guideline Summary for Preoperative Coagulation Testing
  Guideline                     Summary of recommendations
  American Society of           Consider coagulation testing with platelet count for:
   Anesthesiologists,             Patients with a history of bleeding
   2002G1
                                  Patients with renal dysfunction
                                  Patients with liver dysfunction
                                  Type and invasiveness of surgical procedure (not specified by the guideline)
                                Also recognize that anticoagulant medications may present additional perioperative risk
  British Committee             Bleeding history is recommended for all patients
    for Standards in            Coagulation testing is recommended for patients with positive bleeding history or a clear clinical indication
    Haematology, 2008G2          for testing
  Institute for                 Coagulation testing is recommended for:
    Clinical Systems              Patients with a history of coagulation abnormalities
    Improvement, 2012G3
                                  Patients taking anticoagulant medications
                                  Patients with a recent history suggesting coagulation problems
                                  Patients needing postoperative anticoagulation (baseline testing)
  UK National Institute         Coagulation testing is not recommended for:
   for Clinical Excellence,       ASA class 1 patients* who are undergoing grade 1, 2, or 3 surgery†
   2003G4
                                  ASA class 1 patients* younger than 16 years who are undergoing grade 4 surgery†
                                  ASA class 2 adult patients* who have cardiovascular disease and are undergoing grade 1, 2, or 3 surgery†
                                  ASA class 3 adult patients* who have cardiovascular disease and are undergoing grade 1 or 2 surgery†
                                  ASA class 2 or 3 adult patients* who have respiratory disease and are undergoing grade 1, 2, or 3 surgery†
                                  ASA class 2 adult patients* who have renal disease and are undergoing grade 1 or 2 surgery†
                                For all other patients, including those undergoing neurosurgery or cardiovascular surgery, there was no
                                  consensus regarding which patients should be tested
  ASA = American Society of Anesthesiologists.
  *—ASA patient classifications: 1 = healthy patient; 2 = patient with mild systemic disease; 3 = patient with severe systemic disease.
  †—Surgical grades: 1 = minor; 2 = intermediate; 3 = major; 4 = major+.
  Information from:
  G1. American Society of Anesthesiologists Task Force on Preanesthesia Evaluation. Practice advisory for preanesthesia evaluation. Anesthesiology.
  2002;96(2):485-496.
  G2. Chee YL, Crawford JC, Watson HG, Greaves M; British Committee for Standards in Haematology. Guidelines on the assessment of bleeding risk
  prior to surgery or invasive procedures. Br J Haematol. 2008;140(5):496-504.
  G3. Institute for Clinical Systems Improvement. Health care guideline: preoperative evaluation. 10th ed. Bloomington, Minn.: Institute for Clinical
  Systems Improvement; 2012.
  G4. National Institute for Clinical Excellence. Preoperative tests: the use of routine preoperative tests for elective surgery. http://www.nice.org.uk/
  nicemedia/pdf/CG3NICEguideline.pdf. Accessed December 12, 2012.
March 15, 2013   ◆   Volume 87, Number 6                          www.aafp.org/afp                                         American Family Physician