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Induced Fit: A Change in The Shape of An Enzymes Activate Size Lock & Key Model: The Enzyme of Enzyme Action (The Enzyme Joins With Substrate by Is

Enzymes are protein molecules that act as biological catalysts, lowering the activation energy needed for chemical reactions. They can be reused, work inside or outside cells, and only catalyze one type of reaction. Enzymes work via the lock and key or induced fit models - the substrate fits into the active site or the enzyme changes shape to accommodate the substrate. An enzyme's activity is affected by environmental conditions like temperature and pH as well as the concentrations of the enzyme and its substrate. Competitive inhibitors enter the active site instead of the substrate, while non-competitive inhibitors bind elsewhere and induce a shape change in the enzyme.
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0% found this document useful (0 votes)
41 views1 page

Induced Fit: A Change in The Shape of An Enzymes Activate Size Lock & Key Model: The Enzyme of Enzyme Action (The Enzyme Joins With Substrate by Is

Enzymes are protein molecules that act as biological catalysts, lowering the activation energy needed for chemical reactions. They can be reused, work inside or outside cells, and only catalyze one type of reaction. Enzymes work via the lock and key or induced fit models - the substrate fits into the active site or the enzyme changes shape to accommodate the substrate. An enzyme's activity is affected by environmental conditions like temperature and pH as well as the concentrations of the enzyme and its substrate. Competitive inhibitors enter the active site instead of the substrate, while non-competitive inhibitors bind elsewhere and induce a shape change in the enzyme.
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1. What is enzyme?

Enzymes are protein molecules which can be defined as biological catalysts

2. What is susbstrate?
The substance that reduces the activity of an enzyme acts upon it.

3. What is activation energy?


Energy to start chemical reaction

4. Enzyme Properties
- Can be used again and again
- Can work inside a cell or out of the cell
- Can acts only one type reaction
- Work by lowering actiovation energy of the reaction they catalyse
- Most enzymes names end in –ase-
- Modern hypothesis is called the induced fit

5. Lock and key & induced fit (mode of action of enzyme )


Induced fit : A change in the shape of an enzymes activate size
Lock & key model : The enzyme of enzyme action ( the enzyme joins with substrate by is
activate site form enzyme-substrate complex

6. Vactor of enzyme activation


- Enviromental Conditions ( Temperature , Ph )
At high temperature the shape of the activate site is changeed. This process called
denaturation
- Enzyme concentration & substrate concentration
- Enzyme in habitors
7. Graph

8. Competitive & non-competitive Inhibitor

Competitive : A substance that reduces the activity of an enzyme by entering the active site in
place of substrate, whose stucture it mimics.

Non competitive : Inhibitors that do not enter the active site, but bind to another part of the
enzyme causing the enzyme to change its shape, which in turn alters the active site

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