GERD
Gastroesophageal reflux disease (GERD) occurs when stomach acid
frequently flows back into the tube connecting your mouth and
stomach (esophagus). This backwash (acid reflux) can irritate the
lining of your esophagus.
Many people experience acid reflux from time to time. GERD is mild
acid reflux that occurs at least twice a week, or moderate to severe
acid reflux that occurs at least once a week.
Most people can manage the discomfort of GERD with lifestyle
changes and over-the-counter medications. But some people with
GERD may need stronger medications or surgery to ease symptoms.
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Symptoms
Common signs and symptoms of GERD include:
A burning sensation in your chest (heartburn), usually after
eating, which might be worse at night
Chest pain
Difficulty swallowing
Regurgitation of food or sour liquid
Sensation of a lump in your throat
If you have nighttime acid reflux, you might also experience:
Chronic cough
Laryngitis
New or worsening asthma
Disrupted sleep
When to see a doctor
Seek immediate medical care if you have chest pain, especially if you
also have shortness of breath, or jaw or arm pain. These may be signs
and symptoms of a heart attack.
Make an appointment with your doctor if you:
Experience severe or frequent GERD symptoms
Take over-the-counter medications for heartburn more than twice
a week
More Information
Gastroesophageal reflux disease (GERD) care at Mayo Clinic
GERD: Can certain medications increase severity?
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Causes
GERD is caused by frequent acid reflux.
When you swallow, a circular band of muscle around the bottom of
your esophagus (lower esophageal sphincter) relaxes to allow food and
liquid to flow into your stomach. Then the sphincter closes again.
If the sphincter relaxes abnormally or weakens, stomach acid can flow
back up into your esophagus. This constant backwash of acid irritates
the lining of your esophagus, often causing it to become inflamed.
Risk factors
Conditions that can increase your risk of GERD include:
Obesity
Bulging of the top of the stomach up into the diaphragm (hiatal
hernia)
Pregnancy
Connective tissue disorders, such as scleroderma
Delayed stomach emptying
Factors that can aggravate acid reflux include:
Smoking
Eating large meals or eating late at night
Eating certain foods (triggers) such as fatty or fried foods
Drinking certain beverages, such as alcohol or coffee
Taking certain medications, such as aspirin
Complications
Over time, chronic inflammation in your esophagus can cause:
Narrowing of the esophagus (esophageal stricture). Damage to
the lower esophagus from stomach acid causes scar tissue to
form. The scar tissue narrows the food pathway, leading to
problems with swallowing.
An open sore in the esophagus (esophageal ulcer). Stomach acid
can wear away tissue in the esophagus, causing an open sore to
form. An esophageal ulcer can bleed, cause pain and make
swallowing difficult.
Precancerous changes to the esophagus (Barrett's
esophagus). Damage from acid can cause changes in the tissue
lining the lower esophagus. These changes are associated with an
increased risk of esophageal cancer.