In chemistry, pH is a scale used to specify how acidic or basic a water-based
solution is. Acidic solutions have a lower pH, while basic solutions have a higher
pH. At room temperature (25 °C), pure water is neither acidic nor basic and has a
pH of 7.
Unlike strong acids/bases, weak acids and weak bases do not completely dissociate
(separate into ions) at equilibrium in water, so calculating the pH of these solutions
requires consideration of a unique ionization constant and equilibrium
concentrations. Although this is more difficult than calculating the pH of a strong
acid or base solution, most biochemically important acids and bases are considered
weak, and so it is very useful to understand how to calculate the pH of these
substances. The same basic method can be used to determine the pH of aqueous
solutions of many different weak acids and bases.
An aqueous solution of a weak acid or base contains both the protonated and
unprotonated forms of the compound, so an ICE table can be made and used to
plug in concentrations into an equilibrium constant expression. The ionization
constant for the acid (Ka) or base (Kb) is a measure of how readily the acid donates
protons or how readily a base accepts protons. Because you are calculating pH, you
must solve for the unknown concentration of hydronium ions in solution at
equilibrium.
The pH of a weak base falls somewhere between 7 and 10. Like weak acids,
weak bases do not undergo complete dissociation; instead, their ionization is a
two-way reaction with a definite equilibrium point
Denomination pH range
Ultra acidic < 3.5
Extremely acidic 3.5–4.4
Very strongly acidic 4.5–5.0
Strongly acidic 5.1–5.5
Moderately acidic 5.6–6.0
Slightly acidic 6.1–6.5
Neutral 6.6–7.3
Slightly alkaline 7.4–7.8
Moderately alkaline 7.9–8.4
Strongly alkaline 8.5–9.0
Very strongly alkaline > 9.0