Contributions to the Chemistry of the Urine.Paper IV. On So-Called Chylous Urine.

[Abstract]
Author(s): H. Bence Jones
Source: Abstracts of the Papers Communicated to the Royal Society of London, Vol. 5
(1843 - 1850), pp. 930-932
Published by: Royal Society
Stable URL: http://www.jstor.org/stable/111075
Accessed: 28-02-2018 07:39 UTC

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 930

their places of maximum and minimum action accord with the effects
of induced currents. Time has great effect over results produced
by currents induced in the mass, and none over those due to
polarity. By this test the effects of the diamagnetic metals are
found due to induced currents.
The phenomena produced by the use of the present apparatus
are then shown to be in close and direct relation to the phenomena
of revulsion formerly described by the author: the parallel is closely
carried out and extended, and both sets of effects referred to one
and the same cause,
The author endeavours to repeat an experiment described by
IReich, but without success; and he finds that even when iron is
used no arrangement of magnets can produce any test of polarity
at all comparable to the use of an astatic needle or to suspension
between the poles of a powerful magnet, and thinks that arrange-
ments which are thus less sensible with iron are not likely to be
more sensible with diaimagnetic metals, even if they are polar.
Finally, the author does not consider that the idea of diamagnetic
polarity has gained as yet any additional proof bevond the fact that
diamagnetic bodies, such as bismuth and phosphorus, are repelled
by one or both magnetic poles; he does not reject the idea of
polarity, but his opinion or judgment remains the same as at the
time of its announcement in 1845.

A paper was also read, entitled s Clontributions to the Chemistry

of the Urine.-Paper IV. On so-called Chylous Urine." By H.
Bence Jones, M[.D., A.M., F.L.S. &c.
The definition given of chylous urine is, that it is urine which is
white from the suspension of fatty matter in it. An opportunity of
observing a case of this disease having occurred to the author, he w'as
led to make the experiments described in this paper. A harness-
maker, age 32, half-caste, who had lived in London for twelve years,
had been passing such water for nine months. On examination of
the water made at 2 P.M. it solidified, looking like blanc-mange in
ten minutes. It was very feebly acid, contained fibrin, albumen,
blood-globules and fat; specific gravity=1015. 1000 grs. of this
urine gave-
44'42 grs. total solid residue<,
8-01 grs. total ash.
11-03 grs. albumen.
8'37 grs. fat.
13'26 grs. urea and extractive matter.
?75 gr. loss.
955'58 grs. water.
In order to watch the variations produced by food and exercise
in the appearance of the urine, every time the urine was made, for
five days and nights it was passed into bottles marked with the hour.
From these observations, and more particularly from the third, fourth,
and sixth days, it was evident that the fibrin and albumen appear in
the urine when no fat is there, a-nd that the albuminous urine occurs

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 931

before food has been taken, and disappears during the night with
perfect rest. Thus the fourth day, at 7h 15m A,M., on first getting up
the urine contained the slightest trace of albumen. The specific gra-
vity=1027; the precipitate by alcohol=0?8 gr..per 1000 grs. urine.
At 9 A 50m A.M., just befqbre breakiast, the urine formed a solid
coagulum free firom fatty matter, but contained a visible deposit of
blood. Specific gravity= 0150 6 ;. the precipitate by alcohol=14'l1
grs. per 1000 grs. of urine.
At 11 A.M., the urine was chylous or white from fatty matter.
Further experiments on the influence of rest and motion in les-
sening or increasing the albumen in the urine previous to food are
then given.
On five different mornings, by rising early or late, and by col-
lecting the precipitate from the urine by alcohol, the influence of
rest and motion was determined. The author states that he could
fix beforehand whether the urine should be albuminous or not, by
directing the patient to get up, or to lie still.
The patient was bled and the serum was opalescent, but did not
clear with sether: the blood contained no excess of fat. 1000 parts
of blood gave-
2663 grs. fibrin.
159'3 grs. blood-globules.
78'1 grs. solids of serum.
240'03 grs. total residue.
759'97 grs. water.
The urine made the same day was examined at different hours;
that made immediately before the bleeding was quite wshite, and that
made an hour and a half afterwards was very milky also. Specific
gravity = 1018. 1000 grns. of urine gave-,
56'87 grs. total residue.
10'80 grs. total ash.
13'95 grs. albumen.
7*46 grs. fht.
24'06 grs. urea, &c.
'60 gr. loss.
943'13 grs. water.
The conclusions froil these experiments are,-
1. That so-called chylous urine, besides fat, may cointain albumen,
fibrin, and healthy blood-globules.
2. That, although the fat passes off in the urine after food is taken,
yet the albumen, fibrin and blood-globules are thrown out before
any food has been taken. During perfect rest the albumen ceases
to be excreted; and it does not appear in quantity in the urine even
after food is taken, provided there is perfect rest. A short time after
rising early the urine may coagulate spontaneously, although no fat
is present; and this may happen previous to food, when the urine is
free from fat,
S. Though the urine made just before and a short time after
bleeding was as milky as it usually was at that hour of the day, yet
S*

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the
the serum
serumofof thethe
blood
blood
was was
not milky:
not milky:
it did not
it did
contain
not acontain
larger a larger
quantity
quantityofof fatfat
than
thanhealthy
healthy
bloodblood
does. does.
The
The general
general results
resultsare,-
are,-
1.
1. That
Thatthethemost
mostimportant
importantchanges
changes
in the in
urine
theinurine
this disease
in this disease
take
takeplace
placeindependently
independently of the
of influence
the influence
of digestion.
of digestion.
2.
2. That
Thatthetheurine
urinein one
in one
respect
respect
only resembles
only resembles
chyle, and
chyle,
that and that
is
is in
incontaining,
containing,after
after
digestion,
digestion,
a largea quantity
large quantity
of fat inof
a very
fat in
fine
a very fine
state
stateof
ofdivision.
division.TheThe
supposition
supposition
that the
that
disease
the disease
consists consists
in an in an
accumulation
accumulation of of
fatfat
in the
in the
blood,
blood,
whichwhich
is thrown
is thrown
out by the
outkidneys,
by the kidneys,
carrying
carryingwith
with
it albumen,
it albumen,fibrin,
fibrin,
blood-globules
blood-globules
and salts,
and
is altogether
salts, is altogether
disproved,
disproved, both
bothby by
actual
actual
analyses
analyses
of theof
blood,
the and
blood,
by the
andfrequent
by the frequent
occurrence
occurrence ofof
a jelly-like
a jelly-like
coagulum
coagulum
in thein
urine
thewhen
urinenowhen
white nofatty
white fatty
matter
mattercancanbebe
seenseen
to be
to present.
be present.
3.
3. The
Thedisease
disease consists
consists
in some
in some
changechange
in the inkidney
the kidney
by whichby which
fibrin,
fibrin,albumen,
albumen, blood.globules
blood.globules
and salts
andare
saltsallowed
are allowed
to pass out,
to pass out,
whenever
wheneverthe the
circulation
circulationthrough
through
the kidney
the kidney
is increased;
is increased;
and if at and if at
the
the same
sametimetimefatfat
is present
is present
in the
inblood,
the blood,
it escapesit escapes
also into also
the into the
urine.
urine.That
That this
this
change
change
of structure
of structure
is not is
visible
not tovisible
the naked
to the
eyenaked eye
on
on post-mortem
post-mortem examination,
examination,Dr. Prout
Dr. Prout
long since
long demonstrated;
since demonstrated;
and
and inina acase
case
of of
this
this
disease
disease
which which
was inwas
St. George's
in St. George's
Hospital, Hospital,
and and
was
was examined
examined at at
Plymouth,
Plymouth, no disease
no disease
of the ofkidney
the kidney
was observed.
was observed.
From
Fromthe thetotal
total
absence
absence
of fibrinous
of fibrinous
casts of
casts
the of
tubes
thefrom
tubes
thefrom
urine, the urine,
it
it is
isnot
notimprobable
improbable thatthat
by the
by microscope
the microscope
a difference
a difference
may be de-
may be de-
tected
tectedininthethestructure
structureof the
of mammary
the mammary processes,
processes,
rather than
rather
in than in
that
thatof ofthe
the
cortical
cortical
partpart
of the
of kidneys.
the kidneys.

Mlarch
Mlarch21,
21,1850.
1850.

RICHARD
RICHARDOWEN,
OWEN,Esq.,
Esq.,
Vice-President,
Vice-President,
in the in
Chair.
the Chair.

The
The following
followingletter
letter
from
from
iiMr.iiMr.
Addington
Addington
to the Secretary
to the Secretary
was was
read.
read.
Foreign
ForeignOffice,
Office,March
March
20th,
20th,
1850.1850.
SIR,-I
SIR,-Iam
amdirected
directed
by by
Viscount
Viscount
Palmerston
Palmerston
to sendto
to send
you, for
to you, for
the
the information
informationof of
the the
President
President
and Council
and Council
of the Royal
of theSociety,
Royal Society,
an
an extract
extractofof
a letter
a letter
which
which
his Lordship
his Lordship
has received
has received
from Mr.from
JamesMr. James
Richardson,
Richardson, stating
stating
thatthat
in the
in month
the month
of November
of November
last, a fall
last,
of a fall of
aerolites
aeroliteshad
hadtaken
taken
place
place
on the
on coast
the coast
of Barbary
of Barbary
attendedattended
with a with a
brilliant
brilliantstream
streamof of
light,
light,
which
which
extended
extended
from Tunis
fromtoTunis
Tripoli,
tosome
Tripoli, some
of
of the
thestones
stones
falling
falling
in the
in latter
the latter
city. city.
I am, Sir,
Your most obedient, humble Servant,
H. W. ADDINGTON.
The Secretary to the Royal Society.
Extract of a letter from Mr. Richardson, dated off Jerbah,
25th January 1850.
"I will trouble your Lordship by the mention of the astronomic

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