PHINMA UNIVERSITY OF PANGASINAN
COLLEGE OF HEALTH SCIENCES
Nursing Department
DRUG STUDY
DRUG NURSING
DRUG INDICATION ACTION CONTRAINDICATION ADVERSE EFFECT
INTERACTION CONSIDERATION
Generic Name: Acute intestinal Disturbs DNA synthesis Azathioprine, Contraindicated to: CNS: dizziness, headache, Monitor I.V. site.
amebiasis, amebic liver in susceptible bacterial fluorouracil: Hypersensitivity to ataxia, vertigo, Avoid prolonged use
abscess, trichomoniasis, organisms increased risk of drug, other incoordination, of indwelling
Metronidazole acute infections caused leukopenia nitroimidazole insomnia, fatigue catheter.
by susceptible strains of Cimetidine: derivatives, or EENT: rhinitis, sinusitis, Evaluate hematologic
anaerobic bacteria and decreased parabens (topical form pharyngitis studies, especially in
Brand Name: preoperative and metronidazole only) GI: nausea, patients with history
postoperative metabolism First-trimester vomiting, diarrhea, of blood dyscrasias.
prophylaxis for patients ,increased risk of pregnancy in patients abdominal pain, furry As appropriate,
Flagyl undergoing colorectal toxicity with trichomoniasis tongue, glossitis, dry review all other
surgery. Disulfiram: acute mouth, anorexia significant and life-
psychosis and Precautions: GU: dysuria, dark urine, threatening adverse
confusion Severe hepatic incontinence reactions and
Phenobarbital: impairment interactions,
Drug Classification: increased History of blood
metronidazole dyscrasias, seizures, or
Nitroimidazole metabolism, other neurologic
Derivative decreased efficacy problems
Breastfeeding patients
Children
SUBMITTED BY: KRISTINE JOY C. ESCLETO
PHINMA UNIVERSITY OF PANGASINAN
COLLEGE OF HEALTH SCIENCES
Nursing Department
DRUG STUDY
DRUG NURSING
DRUG INDICATION ACTION CONTRAINDICATION ADVERSE EFFECT
INTERACTION CONSIDERATION
Generic Name: Treatment of vascular Stimulates alpha- Beta-adrenergic Hypersensitivity to CNS: headache, Monitor ECG
failure in shock, adrenergic receptors, blockers: blocked drug or its weakness, anxiety, continuously during
shock like states, increasing blood cardiostimulatory effects components restlessness, tremor, I.V. administration;
Phenylephrine drug-induced pressure and causing of Phenylephrine light-headedness, monitor blood
Severe hypertension
hypotension or pronounced Ventricular tachycardia dizziness, drowsiness, pressure every 5 to
hypersensitivity vasoconstriction in skin, Bretylium, Angle-closure insomnia, hallucinations, 15 minutes until it
To overcome mucous membranes, and sympathomimetics: glaucoma nervousness, stabilizes, then every
paroxysmal mucosa. Produces serious arrhythmias Aneurysm (10% restlessness, 30 to 60 minutes.
Brand Name: mydriasis by contracting giddiness, prolonged
supraventricular ophthalmic solution) Monitor central
tachycardia pupillary Furazolidone: excessive During intraocular psychosis, venous pressure and
Neo-Synephrine To prolong spinal dilator muscle hypertension surgery when orofacial dystonia fluid intake and
anesthesia corneal epithelial output. Keep in mind
Vasoconstrictor in Guanethidine, barrier has been CV: hypertension, that drug doesn’t
regional anesthesia methyldopa: decreased disturbed palpitations, tachycardia, eliminate need for
Drug Classification: antihypertensive effects bradycardia, arrhythmias
To maintain an (ophthalmic solution) fluid resuscitation.
adequate level of BP Elderly patients with Assess CBC; watch for
Alpha Specific during spinal and Halogenated severe arteriosclerotic evidence of
Adrenergic Agonists inhalation anesthesia hydrocarbon or cerebrovascular blood dyscrasias.
anesthetics: disease Monitor I.V. site;
serious arrhythmias extravasation can
cause tissue damage.
MAO inhibitors: severe
headache,
hypertension
SUBMITTED BY: KRISTINE JOY C. ESCLETO
PHINMA UNIVERSITY OF PANGASINAN
COLLEGE OF HEALTH SCIENCES
Nursing Department
DRUG STUDY
DRUG NURSING
DRUG INDICATION ACTION CONTRAINDICATION ADVERSE EFFECT
INTERACTION CONSIDERATION
Generic Name: Management of Acts on beta2-adrenergic Drug-drug: Angina pectoris CNS: tremors, anxiety, During I.V.
bronchospasm during receptors, causing Cyclopropane, Angle-closure insomnia, administration,
anesthesia; a relaxation of bronchial epinephrine, glaucoma headache, dizziness, monitor ECG and
Isoproterenol vasopressor in shock smooth muscle; halogenated general Tachyarrhythmias asthenia,
vital signs carefully.
Adjunct in the acts on beta1-adrenergic anesthetics: Tachycardia or heart nervousness
receptors in increased risk of block caused by Assess patient’s
management of shock
and in the treatment heart, causing positive arrhythmias digitalis intoxication CV: palpitations, response to drug
of cardiac standstill inotropic and Propranolol, other beta- Ventricular tachycardia, angina, and adjust I.V.
Brand Name: or arrest; carotid chronotropic effects and adrenergic arrhythmias that rapid blood pressure infusion rate
sinus increasing cardiac blockers: antagonism of warrant inotropic changes, arrhythmias, accordingly.
Isuprel hypersensitivity; output. Also lowers bronchodilating therapy cardiac arrest, Stokes- Closely monitor
heart block; peripheral vascular effects Labor, delivery, Adams attacks
arterial blood gas
ventricular resistance in skeletal breastfeeding
tachycardia, and muscle and Drug-diagnostic tests: EENT: pharyngitis, visual values, urine output,
ventricular inhibits antigen-induced Glucose: blurring and central venous
Drug Classification: tachycardia histamine increased level pressure.
release. GI: nausea, vomiting, Stay alert for
Beta Specific heartburn rebound
Adrenergic Agonists bronchospasm.
Metabolic:
hyperglycemia
Respiratory: bronchitis,
dyspnea,
increased sputum,
pulmonary edema,
bronchospasm
SUBMITTED BY: KRISTINE JOY C. ESCLETO
PHINMA UNIVERSITY OF PANGASINAN
COLLEGE OF HEALTH SCIENCES
Nursing Department
DRUG STUDY
DRUG NURSING
DRUG INDICATION ACTION CONTRAINDICATION ADVERSE EFFECT
INTERACTION CONSIDERATION
Generic Name: Hypertension alone or Blocks stimulation of Adrenergic Hypersensitivity to CNS: fatigue, asthenia, Monitor ECG and vital
with other oral drugs, beta1- and beta2- bronchodilators, drug anxiety, depression, signs, especially
especially diuretics adrenergic receptor sites theophylline: decreased Bronchospastic dizziness, paresthesia, blood pressure.
Labetalol and alpha1- efficacy of these drugs drowsiness,
Parenteral disease Assess
preparation: Severe adrenergic receptors, Overt heart failure, insomnia, memory loss, cardiovascular,
hypertension decreasing Antihypertensives, cardiogenic shock nightmares, respiratory, and
Control of BP in myocardial contractile nitrates: additive Second- or third- mental status changes neurologic status
Pheochromocytoma; force and hypotension degree atrioventricular closely to detect
Brand Name: enhancing coronary CV: orthostatic adverse reactions.
clonidine withdrawal Block
hypertension artery blood flow Digoxin: additive Severe bradycardia hypotension, peripheral Monitor CBC, blood
Normodyne Trandate and myocardial bradycardia Conditions associated vasoconstriction, glucose level, and
perfusion. Net effect is with severe and bradycardia, liver function tests
decreased heart rate and Dobutamine, dopamine: prolonged hypotension arrhythmias, heart failure
blood reduced beneficial
pressure. cardiovascular effects of EENT: blurred vision, dry
Drug Classification: these drugs eyes, nasal congestion
General anesthetics,
Nonselective verapamil: additive GI: nausea, diarrhea,
Adrenergic Blocking myocardial depression constipation
Agents
MAO inhibitors: GU: erectile dysfunction,
hypertension decreased libido
SUBMITTED BY: KRISTINE JOY C. ESCLETO
