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Drug Study Paracetamol

Paracetamol is an analgesic and antipyretic that reduces fever through its action on the hypothalamus and provides temporary relief from mild to moderate pain through an unknown mechanism that may involve the peripheral nervous system. It is generally well tolerated but can cause liver toxicity, even at moderate doses, especially in individuals with poor nutrition or a history of heavy alcohol use, and its use is contraindicated in those with hypersensitivity to paracetamol or related drugs. Nurses should monitor patients for signs of hepatotoxicity or other potential side effects.

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Iris Balino
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0% found this document useful (0 votes)
2K views1 page

Drug Study Paracetamol

Paracetamol is an analgesic and antipyretic that reduces fever through its action on the hypothalamus and provides temporary relief from mild to moderate pain through an unknown mechanism that may involve the peripheral nervous system. It is generally well tolerated but can cause liver toxicity, even at moderate doses, especially in individuals with poor nutrition or a history of heavy alcohol use, and its use is contraindicated in those with hypersensitivity to paracetamol or related drugs. Nurses should monitor patients for signs of hepatotoxicity or other potential side effects.

Uploaded by

Iris Balino
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Drug Action Indication Contraindication Side Effects Nursing Consideration

Generic Name: Produces Fever reduction. Hypersensitivity Body as a Monitor for S&S of:
Paracetamol analgesia by Temporary to Whole: hepatotoxicity, even with
unknown relief of mild to acetaminophen Negligible with moderate acetaminophen
Brand Name: mechanism, moderate pain. or phenacetin; recommended doses, especially in
Pfizer perhaps by use with dosage; rash. individuals with poor
action on alcohol. Acute nutrition or who have
Dosage: peripheral poisoning: ingested alcohol over
150mg nervous Anorexia, prolonged periods;
system. nausea, poisoning, usually from
Frequency: Reduces fever vomiting, accidental ingestion or
PRN Q4 by direct action dizziness, suicide attempts; potential
on lethargy, abuse from psychological
Classification: hypothalamus diaphoresis, dependence (withdrawal
Central heat-regulating chills, has been associated with
nervous center with epigastric or restless and excited
system agent; consequent abdominal responses).
nonnarcotic peripheral pain, diarrhea;
analgesic, vasodilation, onset of
antipyretic sweating, and hepatotoxicity
dissipation of —elevation of
heat. serum
transaminases
(ALT, AST) and
bilirubin;
hypoglycemia,
hepatic coma,
acute renal
failure (rare).
Chronic
ingestion:
Neutropenia,
pancytopenia,
leukopenia,
thrombocytope
nic purpura,
hepatotoxicity
in alcoholics,
renal damage.

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