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Mekanisme Lipid

The document summarizes cholesterol metabolism pathways in the human body, including exogenous and endogenous pathways. The exogenous pathway involves ingestion of cholesterol from food and its transport through chylomicrons. The endogenous pathway involves liver production of VLDL that circulates and transforms into IDL and LDL. A reverse cholesterol transport pathway involves HDL removing cholesterol from tissues and transporting it back to the liver.

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0% found this document useful (0 votes)
68 views4 pages

Mekanisme Lipid

The document summarizes cholesterol metabolism pathways in the human body, including exogenous and endogenous pathways. The exogenous pathway involves ingestion of cholesterol from food and its transport through chylomicrons. The endogenous pathway involves liver production of VLDL that circulates and transforms into IDL and LDL. A reverse cholesterol transport pathway involves HDL removing cholesterol from tissues and transporting it back to the liver.

Uploaded by

sela
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© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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JALUR EKSOGEN

ADIPOSA (TG)

TG
KOLESTEROL
FFA
ESTER
KOLESTEROL
KOLESTERO Enzim LPL
L
KILOMIKRON TRIGLISERID
REMNANT
USUS HALUS

SIRKULASI
TG
KOLESTEROL

ESTER
TG KL FFA DUCTUS
THORACICUS

MAKANAN

TG KILOMIKRON LIMFE

Fosfolipid =
Apolipoprotein =
JALUR ENDOGEN
KOLESTEROL
ESTER

FOAM CELL

VLDL K Apo B100

Enzim LPL

IDL KOLESTEROL ESTER

LDL
KOLESTEROL ESTER

Keterangan :

 Kolesterol

Triglisrid

 SR-A
JALUR REVERSE
CHOLESTEROL TRANSFERASE

Keterangan :
KOLESTEROL
ESTER
= SR-B1

VLDL K
= TRIGLISERID

C = KOLESTEROL

E
Enzim LPL = ABC-1
T
KOLESTEROL ESTER
P

IDL
Lechitin Cholesterol Acyltransferase

LDL
Apo A

HDL Apo C
Apo E

Nascent HDL
JALUR BETA OKSIDASI

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