Coley 2019
Coley 2019
encountered in the field                                                         C   outline the different trauma scoring systems available and their
                                                                                    use
                                                                                C   describe the initial management of trauma patients specifically
Emma Coley                                                                          relating to pelvic fractures, ballistic trauma and traumatic car-
Sarah Fadden                                                                        diac arrest
                                                                                C   explain the initial management and resuscitation of patients
                                                                                    relating to burns and head injuries
Abstract                                                                        C   demonstrate the placement of the Combat Application Tourni-
This article covers the principles of trauma care relating to specific               quet when clinically indicated
competencies within the military higher training module. The majority
of these principles relate to the pre-hospital assessment and manage-
ment of patients, introducing some of the nuances of military medicine
in comparison to civilian practice.                                           platform for trauma data registries and widely used for trauma
Keywords Burns; cardiac arrest; forensic ballistics; head injury;             research.1
military medicine; pelvis; thoracotomy; tourniquet; trauma severity              Less frequently used anatomic systems include New Injury
indices; wounds and injuries                                                  Severity Score (NISS), ICD derived injury severity score (ICISS)
                                                                              and Anatomic Profile (AP).
Royal College of Anaesthetists CPD Matrix: 3A10, 3A14, 2A02, 2F01, 1B04
ANAESTHESIA AND INTENSIVE CARE MEDICINE xxx:xxx 1 ! 2019 Published by Elsevier Ltd.
 Please cite this article as: Coley E, Fadden S, Initial assessment and management of trauma encountered in the field, Anaesthesia and intensive
 care medicine, https://doi.org/10.1016/j.mpaic.2019.09.005
                                                      TRAUMA AND MILITARY ANAESTHESIA
loss. Mortality rates for all types of pelvic fracture have                laparotomy may cause decompression and re-expansion of the
improved, but they still range from 5e15%.3                                retroperitoneal haematoma due to renewed venous bleeding.
ANAESTHESIA AND INTENSIVE CARE MEDICINE xxx:xxx 2 ! 2019 Published by Elsevier Ltd.
 Please cite this article as: Coley E, Fadden S, Initial assessment and management of trauma encountered in the field, Anaesthesia and intensive
 care medicine, https://doi.org/10.1016/j.mpaic.2019.09.005
                                                      TRAUMA AND MILITARY ANAESTHESIA
situation of a compromised or at risk airway, where respiratory            including the surrounding environment, type and amount of
complications have occurred secondary to inhalational injury; for          explosive. Explosion causes rapid conversion of a substance to a
ongoing clinical care (such as wound debridement, skin grafting            gas, substantially increasing the volume by more than a 1000-
or escharotomies); or for treatment of concomitant traumatic               fold. Simultaneous increase in pressure causes the surrounding
injuries. Investigations include blood tests (full blood count, urea       air to be compressed, forming a shock wave. This lasts only
and electrolytes, creatine kinase and arterial blood gas with              milliseconds, but is followed by a longer lower pressure blast
carboxyhaemoglobin), electrocardiogram, chest X-ray, bron-                 wind.7
choscopy (for intubated patients) and urine analysis (output and               Explosions have the potential to inflict multi-system life-
presence of haemoglobinuria or myoglobinuria). These in-                   threatening injuries, directly and indirectly, on multiple patients.
vestigations will help to assess the degree of physiological               This is likely to create mass casualties, causing a major incident.
derangement caused, and to target the resuscitation strategy.              The infrequency of these events creates challenges for local
Monitoring may be challenging in cases where there are burns               emergency services, including triage and initial management.
overlying monitoring sites. Early placement of an arterial line                Blast injuries have several sub-categories, representing
will provide both invasive blood pressure monitoring, for a pa-            mechanisms of tissue injury. These all have implications for
tient who may be haemodynamically compromised and not able                 acute management and anaesthetic planning.
to tolerate a non-invasive cuff, and access for regular arterial               ! Primary blast injuries e direct effect from the blast wave
blood gas analysis. Cross-matching the patient is judicious, as                    and over-pressurisation impulse. This is likely to cause
wound debridement can lead to rapid blood loss.                                    injuries within hollow organs and gas-filled spaces
    Ketamine is particularly useful for induction of patients with                 including middle ear, lung, and large bowel. It has also
cardiovascular instability (e.g., secondary to vasodilatation                      been implicated as a cause of traumatic brain injury (TBI)
caused by burn-induced systemic inflammatory response syn-                         and can affect the extremities.8
drome). It also causes bronchodilatation, which may be helpful if              ! Secondary blast injuries e related to foreign objects and
inhalational injury has occurred. For muscle relaxation, sux-                      debris propelled by the blast wave becoming projectiles.
amethonium is contraindicated from 6 hours until 2 years after a               ! Tertiary blast injuries e caused by blunt impact when the
major burn injury, owing to the risk of severe hyperkalaemia.                      casualty is displaced by the forces of the explosion.
Higher doses of non-depolarizing neuromuscular blocking drugs                  ! Quaternary blast injuries e indirect injuries occurring as
may be required due, in part, to the appearance of extra-junctional                a consequence of the explosion, such as burns and smoke
acetylcholine receptors. Postoperative pain may be significant and                 inhalation.
should be addressed with prompt multimodal analgesia.                          The majority of blast injuries are found in a military envi-
    Mechanical ventilation should employ a lung protective                 ronment, where there is a disproportionate representation of
strategy (e.g. tidal volumes of 6e8 ml/kg). Patients with inha-            extremity injuries due to detonation on or under the ground.
lational injury will require regular pulmonary toilet and bron-            Triage is extremely important for ensuring resources are directed
choscopic lavage. Carbon monoxide poisoning may necessitate                appropriately to those with the most severe injuries, but also
ventilation with 100%, or even hyperbaric, oxygen.                         those with the greatest chance of survival.8 Initial scene assess-
    Intravenous access, fluid resuscitation and electrolyte man-           ment and triaging prioritizes immediate management of life-
agement can be challenging. The Parkland Formula (4ml/kg " %               threatening injuries, such as tourniquet application for major
TBSA burn in adults) provides a useful estimate of the crystalloid         extremity haemorrhage. An advanced trauma life support
volume required for resuscitation during the first twenty-four             approach should be applied to those patients prioritized for
hours after a burn injury has occurred, with half given over the           treatment. In the military setting, improved armouring and
first eight hours and half over the following sixteen hours. Fluid         medical innovations, including haemostatic dressings and tour-
infusions are titrated against clinical response, measuring urine          niquets, have reduced mortality.
output (aiming for > 0.5 ml/kg/hr in adults), intending to restore             On arrival at a medical facility a rapid primary survey often
perfusion of the tissues and organs, whilst minimising oedema.5            leads to re-triaging. The focus is on damage control, allowing
Any electrolyte disturbances should be treated.                            time-limited surgical procedures to be carried out, such as rapid
    Other anaesthetic considerations include measures to prevent           initial wound debridement to reduce infection rates. This is fol-
hypothermia in patients whose inability to autoregulate while              lowed by patient optimization in a critical care environment
anaesthetized is exacerbated by evaporation of fluid from their            before definitive management.
wounds. This may be achieved by increasing the ambient tem-
perature, using warming blankets and infusing pre-warmed fluids.           Ballistics
    The anaesthetic management of a patient with severe burns              Ballistics is the science of projectiles and firearms. Terminal
requires multi-system assessment and support. Depending on the             ballistics is the study of how a projectile behaves when it hits a
circumstances, suspicion of other concurrent trauma injuries               target and transfers its kinetic energy. If the target is biological,
must be explored and addressed.                                            the term wound ballistics is applied.
                                                                              Severity of any penetrating injury is related to the vicinity
Blast and ballistic injuries                                               of the wound track to vital organs and large vessels. Dy-
                                                                           namics of the projectile and local tissue reaction influence the
Blast injury                                                               nature of the gunshot wound. Energy transfer to the tissue is
Blast injury secondary to bombs and explosions can cause                   determined by the kinetic energy of the bullet (KE ¼ ½ mv2),
unique patterns of injury. Damage created depends on factors               but also the specific tissue resistance to bullet penetration.
ANAESTHESIA AND INTENSIVE CARE MEDICINE xxx:xxx 3 ! 2019 Published by Elsevier Ltd.
 Please cite this article as: Coley E, Fadden S, Initial assessment and management of trauma encountered in the field, Anaesthesia and intensive
 care medicine, https://doi.org/10.1016/j.mpaic.2019.09.005
                                                      TRAUMA AND MILITARY ANAESTHESIA
Where there is only an entry wound, all the bullet’s energy                and reactivity, particularly pre- and post-administration of
has been distributed to the tissues. Where exit wounds exist,              anaesthetic drugs.
they are commonly larger and more irregular due to bullet                      The anaesthetic management of a TBI patient may impact
tumbling.9                                                                 critically on their outcome. A rapid sequence induction is not
    With high-velocity projectiles, cavitation is a process where          without risk of complications, particularly in a group of patients
tissue displacement lags behind the bullet. A temporary larger             whose already unstable physiology may be further compromised
cavity is formed, which then closes down to leave a permanent              by anaesthetic drugs.11 Agents that are commonly used to induce
wound track. The vacuum created during this process can also               anaesthesia rapidly in the pre-hospital environment are fentanyl,
entrain foreign material. This temporary track can vary in size,           ketamine and rocuronium. A modified technique using intrave-
depending on energy deposition and bullet motion, but can have             nous fentanyl, ketamine and rocuronium in a 3:2:1 (unit drug per
a devastating effect on susceptible organs.9                               kilogram patient weight) ratio, or 1:1:1 ratio in more haemody-
                                                                           namically compromised patients, achieves suitable intubating
Military anaesthesia for head injuries                                     conditions. Concerns regarding the use of ketamine for TBI pa-
                                                                           tients, in whom a high MAP could exacerbate a raised ICP, have
Primary traumatic brain injury (TBI) is the initial physical
                                                                           largely been disproved.12 Careful laryngoscopy technique will
injury caused to brain parenchyma by mechanical forces. This
                                                                           help to prevent excessive sympathetic stimulation. Rocuronium
results in activation of an inflammatory cascade, with further
                                                                           is a useful muscle relaxant in trauma, because it has a rapid
tissue damage, oedema, and decreased cerebral perfusion
                                                                           onset, long duration of action and can be reversed pharmaco-
pressure (CPP). Patients with apparent or suspected TBI are
                                                                           logically if required.
vulnerable to secondary brain injury. Rapid management of TBI
                                                                               Cervical spine problems should be suspected in trauma pa-
patients, including institution of neuroprotective strategies, is
                                                                           tients where their injury involves a large transfer of energy or
essential for moderating the impact of this cause of morbidity
                                                                           obvious injury to the neck. Stabilization of the cervical spine
and mortality.
                                                                           (with manual in-line techniques during intubation) should be
    Any reduction in conscious level will render the patient at risk
                                                                           undertaken. Anaesthesia can be maintained safely using either
of airway obstruction and aspiration. Intubation and mechanical
                                                                           inhalational or intravenous agents. Inhalational anaesthetics
ventilation may be indicated, both for airway protection and to
                                                                           produce a dose-dependent increase in cerebral blood flow (CBF)
facilitate control of a patient’s physiological parameters. Opti-
                                                                           that may lead to a rise in ICP, although this is less likely with a
mizing oxygenation (SaO2 $ 90%) and ventilation (PaCO2 35
                                                                           minimum alveolar concentration of <1, but most inhalational
e40 mmHg) helps reduce intracerebral vasodilatation associated
                                                                           agents also lower the cerebral metabolic rate (CMRO2). Nitrous
with hypoxemia and hypercarbia, counteracting any further rise
                                                                           oxide should be avoided, because it increases CBF and CMRO2.
in intracranial pressure and consequent reduction in CPP (¼
                                                                           All intravenous anaesthetics, apart from ketamine, decrease CBF
mean arterial pressure-intracranial pressure, MAP-ICP).10
                                                                           and CMRO2, although evidence shows that ketamine does not
Although hyperventilation to lower PaCO2 may be used as a
                                                                           cause a rise in ICP.12
temporizing measure for raised ICP, hypocarbia can cause a
                                                                               Placement of an arterial line, for beat-to-beat monitoring of
vasoconstriction-associated decrease in cerebral oxygenation and
                                                                           blood pressure and measurement of blood gas components, is
subsequent intracerebral ischaemia. Sedation will help to reduce
                                                                           recommended. Unless a TBI patient requires either blood
cerebral metabolic requirements and seizure activity.
                                                                           product resuscitation, or a dose of hyperosmolar therapy,
    Neuroprotective management also includes maintenance of
                                                                           isotonic solutions should be administered in favour of hypo-
an adequate blood pressure (systolic $100 mmHg) to maintain
                                                                           tonic ones, because the latter more readily cross the blood brain
CPP.10 Brain Trauma Foundation (BTF) guidelines state that a
                                                                           barrier and worsen cerebral oedema and raised ICP. Finally,
single pre-hospital episode of hypotension (defined as systolic
                                                                           avoidance of hyperthermia, which increases cerebral metabolic
<90 mmHg) in a TBI patient is a statistically independent risk
                                                                           rate, has been shown to be of benefit in TBI.
factor for a poor outcome. This becomes more challenging in the
                                                                               Anaesthetic management of TBI patients is challenging,
context of multi-system trauma, when a balance must be struck
                                                                           particularly in military austere and resource-limited environ-
with permissive hypotension, as part of damage control resus-
                                                                           ments. However, careful monitoring and manipulation of phys-
citation for catastrophic haemorrhage.
                                                                           iological parameters are crucial for preserving and protecting the
    Other strategies to maintain CPP include taping, rather than
                                                                           brain.
tying, the endotracheal tube and positioning the patient 30% head
up, to assist cerebral drainage and lower ICP. If there are clinical
                                                                           Current concepts in the management of traumatic cardiac
signs of a raised ICP (e.g. a dilated pupil), administration of
                                                                           arrest
intravenous hypertonic saline (3e5 ml/kg of 3%) can help to
reduce cerebral oedema by creating an osmotic gradient that                Trauma may be a primary or secondary event in the situation of
mobilizes intracerebral fluid in to the systemic circulation               cardiac arrest of a trauma patient. Differentiation is often
(thereby also augmenting blood pressure, without the subse-                possible, based on the history of the patient and the circum-
quent potent diuresis and possible hypotension associated with             stances of their arrest. It is crucial that a patient who has suffered
mannitol). Plasma sodium levels should be monitored.                       trauma as a result of a medical cardiac arrest is treated according
    It is important to assess a TBI patient’s baseline neurological        to the universal Advanced Life Support (ALS) algorithm. Initial
function, using the Alert, Voice, Pain, Unresponsive (AVPU)                management of traumatic cardiac arrest (TCA) focuses on
scale or Glasgow Coma Scale (GCS), as well as their pupil size             addressing potentially reversible causes simultaneously rather
ANAESTHESIA AND INTENSIVE CARE MEDICINE xxx:xxx 4 ! 2019 Published by Elsevier Ltd.
 Please cite this article as: Coley E, Fadden S, Initial assessment and management of trauma encountered in the field, Anaesthesia and intensive
 care medicine, https://doi.org/10.1016/j.mpaic.2019.09.005
                                                                           TRAUMA AND MILITARY ANAESTHESIA
                                     EUROPEAN
                                     RESUSCITATION                            Traumatic Cardiac Arrest
                                     COUNCIL
Trauma patient
                                                                                Cardiac arrest /
                                                                              Periarrest situation?
                    Hypoxia                                                           UNLIKELY
                    Tension pneumothorax
                                                        Simultaneously address reversible causes
                                                                                                                                              Continue ALS
                                                                                                                                              Start /
                    Tamponade
                    Hypovolaemia
                                                                                                                                                                  Consider immediate
                     Consider termination                                   Return of spontaneous
                                          NO                                                                                                                         resuscitative
                           of CPR                                                circulation?
                                                                                                                                                                    thoracotomy
YES
                                                         Pre-hospital:
                                                          n Perform only life-saving interventions
                                                         In-hospital:
                                                           n Damage control resuscitation
                       www.erc.edu | info@erc.edu
                       Published October 2015 by European Resuscitation Council vzw, Emile Vanderveldelaan 35, 2845 Niel, Belgium
                       Copyright: © European Resuscitation Council vzw Product reference: Poster_SpecCircs_TraumaticCardiacArrest_Algorithm_ENG_20150930
Figure 1 European Resuscitation Council algorithm for the management of traumatic cardiac arrest 2015. (Reproduced with kind permission from:
Truhlar A, Deakin CD, Soar J et al. European Resuscitation Council Guidelines for Resuscitation 2015; 95:148e201.)
ANAESTHESIA AND INTENSIVE CARE MEDICINE xxx:xxx 5 ! 2019 Published by Elsevier Ltd.
 Please cite this article as: Coley E, Fadden S, Initial assessment and management of trauma encountered in the field, Anaesthesia and intensive
 care medicine, https://doi.org/10.1016/j.mpaic.2019.09.005
                                                      TRAUMA AND MILITARY ANAESTHESIA
than on delivery of chest compressions, which are less likely to           air that flows in during inspiration can become trapped in the
be successful under these circumstances (Figure 1).                        pleural space and cause a tension pneumothorax. This can lead
   TCA is broadly categorized as blunt or penetrating but can be           both to hypoxia and an increase in intrathoracic pressure that
managed according to the ‘HOT’ principles: Hypovolaemia,                   impedes venous return to the heart, which may result in cardiac
Oxygenation, Tension pneumothorax/cardiac Tamponade.                       arrest. In a patient in TCA, bilateral chest decompression is
                                                                           achieved more reliably and effectively by open thoracostomies
Hypovolaemia                                                               than needle thoracocentesis. Siting thoracostomies is the first
Haemorrhage control e The majority of external or extremity                step in performing a resuscitative thoracotomy (RT).15
bleeding can be controlled by compression, elevation and
splinting. Open wounds can be packed with haemostatic agents,              Tamponade
such as CELOX-impregnated gauze. Suspected internal and non-               Cardiac tamponade occurs when the pericardial sac is filled with
compressible haemorrhage can be controlled definitively by                 fluid under pressure, resulting in cardiac arrest secondary to
surgical intervention. The CRASH-2 trial shows that intravenous            compromised cardiac function. Tamponade is more common
administration of the antifibrinolytic tranexamic acid is beneficial       with penetrating trauma. TCA in penetrating trauma to the chest
when given within three hours of injury occurring.13                       or epigastrium is one indication for immediate RT. Estimated
                                                                           survival rates for RT are 15% for patients with penetrating chest
Damage control resuscitation (DCR) e This largely becomes                  wounds and 35% for those with penetrating cardiac wounds,
relevant if there is return of spontaneous circulation post-TCA,           contrasting starkly with only 0e2% for patients with blunt chest
and comprises only necessary interventions to establish a sur-             trauma. It is unclear whether blunt trauma patients should un-
vivable physiological status, before definitive injury repair is           dergo RT in the pre-hospital environment. Ultrasonography may
undertaken. Damage control surgery (DCS), for control of hae-              assist with diagnosis of the underlying cause of the TCA. It is
morrhage and treatment of contamination is undertaken                      difficult to determine the elapsed time threshold in a situation of
concurrently with DCR. DCR is synonymous with the concept of               penetrating trauma, although the European Resuscitation Coun-
balanced resuscitation and consists of permissive hypotension              cil Guidelines for Resuscitation 2015 advise that the time from
and haemostatic resuscitation.                                             loss of vital signs to commencing a RT should not exceed ten
    ! Permissive hypotension (which does not apply during                  minutes.
      TCA) involves maintaining a blood pressure that is low
      enough to reduce haemorrhage but high enough to pre-                 Resuscitative thoracotomy15
      serve end-organ perfusion. The overall purpose is to limit             ! Position the patient in the supine position while other
      significant increases in blood pressure (aiming for a sys-                procedures (intubation, IV access) are undertaken.
      tolic of 90 mmHg) until surgical control of bleeding has               ! Apply skin antiseptic.
      been achieved. Higher blood pressure thresholds are                    ! Perform bilateral thoracostomies in the fourth or fifth
      advised for patients with traumatic brain injury, to main-                intercostal space anterior to the mid-axillary line (using
      tain cerebral perfusion pressure. A novel hybrid resusci-                 scalpel and Spencer Wells forceps).
      tation strategy proposes limiting hypotensive resuscitation            ! Join the thoracostomies with a deep scalpel skin incision.
      to sixty minutes duration, to mitigate risks including poor            ! Cut through the intercostal muscles and parietal pleura
      oxygen delivery and significant metabolic acidosis.14                     using medical shears, from the thoracostomies to either
    ! Haemostatic resuscitation (which applies throughout                       side of the sternum.
      management of TCA) involves a balanced strategy advo-                  ! Perform a finger sweep under the sternum.
      cating early use of blood products in ratios similar to whole          ! Cut through the sternum, with medical shears or Gigli saw.
      blood - red blood cells, plasma and platelets administered             ! Open the ‘clamshell’, manually or using rib spreaders.
      1:1:1. This aims to avoid complications associated with                ! Identify the heart and ‘tent’ the pericardium with forceps
      crystalloids, including dilution of red cell and coagulation              before cutting a small hole with scissors, extending it
      factor concentrations, worsening acidosis, exacerbation of                vertically upwards and downwards.
      hypothermia, oedema and immune system activation/                      ! Evacuate any blood clots.
      cellular injury. In a time-critical TCA situation, where               ! If the heart makes no spontaneous movement, flicking it
      hypovolaemia secondary to haemorrhage is a potentially                    may cause contractions to return. If not, perform internal
      reversible cause of the arrest, early and aggressive fluid                cardiac massage. Simultaneous compression of the aorta
      resuscitation is required, even if only crystalloid is                    against the spinal column by an assistant may help to
      available.                                                                maximize coronary and cerebral perfusion.
                                                                             ! Bleeding from myocardial wounds should be controlled
Oxygenation                                                                     initially with a finger. Sutures may be required, placed to
To address hypoxia in TCA, airway management aims to estab-                     avoid occlusion of coronary arteries.
lish a definitive airway by means of intubation and mechanical               ! IV volume should be given.
ventilation, thereby maximizing oxygenation.                                 ! If return of spontaneous circulation (ROSC) is achieved
                                                                                there may be significant internal mammary/intercostal
Tension pneumothorax                                                            vessel bleeding, which may need to be controlled with
Chest trauma can lead to disruption of the visceral pleura, pari-               artery forceps.
etal pleura or tracheobronchial tree. If a one-way valve is formed,          ! In the situation of ROSC the patient will require sedation.
ANAESTHESIA AND INTENSIVE CARE MEDICINE xxx:xxx 6 ! 2019 Published by Elsevier Ltd.
 Please cite this article as: Coley E, Fadden S, Initial assessment and management of trauma encountered in the field, Anaesthesia and intensive
 care medicine, https://doi.org/10.1016/j.mpaic.2019.09.005
                                                      TRAUMA AND MILITARY ANAESTHESIA
Summary
Figure 3 Military emergency compression bandage. (Reproduced with          This article provides a summary of the key management of a
permission.)                                                               number of military trauma scenarios, the principles of which can
                                                                           be applied in the civilian setting. These include avoiding the triad
                                                                           of hypothermia, acidosis and coagulopathy, which requires
Management of TCA is complex and time sensitive. There are                 careful resuscitation. In hospital, local major haemorrhage pro-
potentially life-saving interventions that can be made pre-                tocols are activated to provide early hybrid resuscitation and
hospitally e which should be undertaken by highly trained cli-             targeted blood product administration, directed by thromboe-
nicians using the right equipment, and should not delay defini-            lastography where available. Cell salvage can be used, and rapid
tive care.                                                                 infusion devices allow heated delivery of controlled volume
                                                                           resuscitation. Along with temperature regulation, electrolytes
Combat application tourniquet (CAT) and haemorrhage                        should be monitored and replaced appropriately. Multidisci-
control compression dressing bandage                                       plinary critical care management of major trauma patients is
                                                                           paramount to optimizing their outcome.                           A
Ballistic trauma and battlefield deaths related to extremity injury
and major haemorrhage have been identified as the cause of
more than half of potentially preventable deaths. This has led to          REFERENCES
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 care medicine, https://doi.org/10.1016/j.mpaic.2019.09.005
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ANAESTHESIA AND INTENSIVE CARE MEDICINE xxx:xxx 8 ! 2019 Published by Elsevier Ltd.
 Please cite this article as: Coley E, Fadden S, Initial assessment and management of trauma encountered in the field, Anaesthesia and intensive
 care medicine, https://doi.org/10.1016/j.mpaic.2019.09.005