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Metronidazole

Metronidazole (brand name Flagex) is an antibiotic used to treat various bacterial and protozoal infections. It is typically administered as 500 mg twice daily for 7 days. Metronidazole works by inhibiting DNA synthesis in certain obligate anaerobes, causing their cell death. It is indicated for acute infections caused by susceptible anaerobic bacteria, as well as intestinal amebiasis, amebic liver abscess, trichomoniasis, and bacterial vaginosis. Common adverse reactions include central nervous system effects like headache and gastrointestinal effects like nausea. Nursing responsibilities include administering the drug with food and advising patients not to drink alcohol during treatment.

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0% found this document useful (0 votes)
210 views1 page

Metronidazole

Metronidazole (brand name Flagex) is an antibiotic used to treat various bacterial and protozoal infections. It is typically administered as 500 mg twice daily for 7 days. Metronidazole works by inhibiting DNA synthesis in certain obligate anaerobes, causing their cell death. It is indicated for acute infections caused by susceptible anaerobic bacteria, as well as intestinal amebiasis, amebic liver abscess, trichomoniasis, and bacterial vaginosis. Common adverse reactions include central nervous system effects like headache and gastrointestinal effects like nausea. Nursing responsibilities include administering the drug with food and advising patients not to drink alcohol during treatment.

Uploaded by

iluvmunicamuch
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
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Generic Brand Dosage Mechanism of Indications Contraindications Adverse Nursing

Name Name Action Reactions Responsibilities


Metronidazole Flagex 500 mg 2x Bactericidal > Acute infection > Contraindicated > CNS: > Take the drug
a day for 7 ↓ with susceptible with headache, with food if GI
days. Inhibits DNA anaerobic hypersensitivity to dizziness, upset occurs.
synthesis in bacteria. metronidazole. ataxia, vertigo, > Do not drink
specific (obligate) > Acute intestinal > Use cautiously incoordination, alcohol for 24-72
anaerobes amebiasis with CNS diseases, insomnia, hours of drug use;
↓ > Amebic liver hepatic disease, seizures, severe reaction
Causing cell abscess. candidiasis peripheral may occur.
death > Trichomoniasis. (moniliasis), blood neuropathy, > Your urine may
be a darker color
↓ > Bacterial dyscrasias, fatigue.
than usual.
Antiprotozoal – vaginosis. lactation. > GI:
> Apply the topical
trichomonacidal unpleasant
preparation by
↓ metallic taste, cleansing the area
Amebicidal anorexia, and then rubbing a
↓ nausea, thin film into the
Biochemical vomiting, affected area.
mechanism of diarrhea, GI > Can experience
action is not upset, cramps. drying of the
known. > GU: dysuria, mouth with
incontinence, strange metallic
darkening of the taste, nausea,
urine. vomiting, and
> LOCAL: diarrhea.
thrombophlebiti > Report for
s (IV); redness, severe GI upset,
burning, dizziness, unusual
dryness, and fatigue or
skin irritation weakness, fever,
(topical). chills.

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