BioPure fluid path components,

connect with confidence

About BioPure BioPure fluid path components
BioPure has pioneered the design, development and delivery allow you to connect with confidence
of innovative bioprocessing fluid path components since 1998.
Our strong market focus, aligned with a global presence, »» Q-Clamp
ensures BioPure will continue to be the market leader in Single-handed and tool free sanitary
single-use technology for many years. Tri-Clamp

As part of the Watson-Marlow Fluid Technology Group »» High purity gaskets

(WMFTG), we have combined market expertise in all aspects Platinum-cured silicone gaskets
of fluid transfer; from pumps and tubing, to valves, reinforced
hoses and final fill finish. Always on the leading edge of »» BioClamp
meeting regulatory expectations, we are confident that no Plastic Tri-Clamp
other company can handle high purity biopharmaceutical fluid
application better than WMFTG. »» High pressure hose
Platinum-cured braided hose
Full validation and traceability »» BioBarb
BioPure aims to simplify your production operations, lower Hose barb to Tri-Clamp adaptors
cGMP manufacturing costs and reduce process validation.
»» BioValve
» LOT traceability on every component Variable flow control valve
» Class 7 cleanroom manufacturing and packing
»» Bio Y
» Use of automated technologies including advanced robotics Equal barbed Y connectors
» Continuous improvement of manufacturing procedures
utilising global initiatives
»» BioEndCap
End caps with pull tab for connectors
» All components and materials contain no animal derived
content »» FlatBioEndCap
End caps for connectors
All products are supported by validation guides detailing test
protocols including ISO, USP and extractables.
This enables our customers to quickly assess our component
All BioPure components are suitable for sterilisation by
suitability for their manufacturing process. autoclave and gamma irradiation, gamma stable, up
to 40 kGy.
Biopharmaceutical applications are amongst the most
BioBarbs, FlatBioEndCaps, Bio Ys and BioEndCaps
critical in the world. You need a partner who you can trust, are all moulded from polypropylene.
who understands the process and is able to help achieve Q-Clamps, BioClamps and BioValves are all moulded
compliance and repeatability throughout. from reinforced Nylon 66.
High purity gaskets are moulded from Platinum-cured
silicone.
High pressure hose is extruded from Platinum-cured
silicone with a polyester yarn braid.
 High purity gaskets

Platinum-cured silicone gaskets

PMS 3015 c (C-100 M-30 Y-0 K-20 )
PMS Cool gray 9c (C-0 M-30 Y-0 K-65 ) High purity Platinum-cured silicone gaskets
precision engineered to achieve a smooth bore,
contamination free fluid path under clamping
compression. Available in a range of flanged and
unflanged size options.
»» Post sterilised validation to current USP, EP and FDA
standards

»» Extractables using a multi-solvent approach to BPOG

guidelines

»» Laser etch LOT numbering enables full product traceability

Process security; Quick and qualified

Patented single-handed and tool free sanitary Tri-Clamp, qualified for use in the biopharm
industry.
»» Compatible with wide range of connector geometry
»» Ratchet position identification can aid junction validation
»» Can be fitted with unique Q-Clamp tamper evident identification technology BioClamp
»» Sleek, lightweight design to maximise operator comfort and eliminate any potential
of damage to bags or gloves

Q-Clamp™ is supported by an industry leading validation package for non-wetted components Plastic Tri-Clamp
and meets current industry requirements including ISO 10993: Parts 5, 6, 10, and 11, USP <88> BioClamp® is a patented plastic union clamp,
& USP <87>. Q-Clamp has also been evaluated for extractables using a single solvent approach. specifically designed to meet the needs of busy
pharmaceutical and bioprocessing laboratories.
Q-Clamp introduces the first true tamper evident security solution for
»» Preferred over stainless steel clamps to reduce the
Tri-Clamp® connections. The additional component can also be used distortion on polymeric fittings when subjected to heat
for identification through colour, allowing procedures to specify relevant
areas of the process: »» Tamper evident feature available on the 1/2" to 4"

»» Can be applied pre or post clamp assembly »» Manufactured from borosilicate reinforced nylon, the
BioClamp is lightweight and easy to manipulate
»» Tool free application and removal
»» Available in eight colours; blue, grey, orange, purple, green, red, yellow
and clear
High pressure hose BioValve

Platinum-cured silicone braided hose Variable flow control valve

High pressure flexible hose with a continuously BioValve™ is a precision restriction flow controller
extruded Platinum-cured silicone core in single and shut off valve that has been tested with clear
and double braid options. and braid reinforced silicone tubing.
»» Post sterilised validation to current USP, EP and FDA »» Profiled to minimise flow path turbulence
standards
»» Thread pitch is calibrated to 2mm per turn, permitting
»» Extractables using a multi-solvent approach to BPOG controlled flow restriction
guidelines
»» Can be applied to tubing already in situ
»» Available in either 7.6m (25ft) and 15.2m (50ft) coils

BioBarb Bio Y

Hose barb to Tri-Clamp adaptors Equal barbed Y connectors

BioBarb™ incorporates an oversized barb design Bio Y™ connectors are designed to meet the
which facilitates an extremely strong adhesion to same high performance standards of our BioBarb
the tubing. adaptors.
»» The full through bore diameter ensures smooth transition »» Y junction splits the flow with minimum turbulence to
from tube to adaptor, reducing turbulence optimise flow rate and back pressure

»» The identical ID of barb and tubing allows complete »» Identical ID of barb and tubing allows complete drainage
drainage along an unimpeded flow path along an unimpeded flow path

»» Enhanced Tri-Clamp design reduces the risk of a seal failure »» Size identification moulded into every component for ease
of use
 Q-Clamp and tamper evident cover
Part number Pack size Size Max. operating pressure
1032-0075-0010 10 PCS 1/2" – 3/4" TC 10bar

BioEndCap
1032-0075-0100 100 PCS 1/2" – 3/4" TC 10bar

1032-0150-0010 10 PCS 1" – 1 1/2" TC 10bar

1032-0150-0050 50 PCS 1" – 1 1/2" TC 10bar

Part number Pack size Size Colour

End caps with pull-tab for connectors
1033-0001-0100 100 PCS 1/2" – 3/4" and 1" – 1 1/2" Q-Clamp Natural
BioEndCap™ is designed to terminate a disposable 1033-0002-0100 100 PCS 1/2" – 3/4" and 1" – 1 1/2" Q-Clamp Blue
manifold until a new connection is to be made.
1033-0003-0100 100 PCS 1/2" – 3/4" and 1" – 1 1/2" Q-Clamp Grey
»» Uniquely constructed pull-tab ensures easy removal of 1033-0004-0100 100 PCS 1/2" – 3/4" and 1" – 1 1/2" Q-Clamp Orange
the cap
1033-0005-0100 100 PCS 1/2" – 3/4" and 1" – 1 1/2" Q-Clamp Yellow
»» Pull tab designed for strength but sufficient pliability to avoid
1033-0006-0100 100 PCS 1/2" – 3/4" and 1" – 1 1/2" Q-Clamp Red
damage to any contact materials
1033-0007-0100 100 PCS 1/2" – 3/4" and 1" – 1 1/2" Q-Clamp Green
»» Provides a reliable, repeatable seal when used in combination
1033-0008-0100 100 PCS 1/2" – 3/4" and 1" – 1 1/2" Q-Clamp Purple
with a gasket and clamp
Gaskets (flanged)
Part number Pack size Size I.D x O.D
5101.0100.025 25 1" 0.877" x 1.984"

5101.0150.025 25 1 1/2" 1.377" x 1.984"

5101.0200.025 25 2" 1.875" x 2.520"

5101.0250.025 25 2 1/2" 2.374" x 3.050"

5101.0300.025 25 3" 2.878" x 3.583"

5101.0400.025 25 4" 3.843" x 4.658"

5101.0600.025 25 6" 5.822" x 6.570"

FlatBioEndCap 5101.0800.025 25 8" 7.822" x 8.570"

Gaskets (unflanged)
Part number Pack size Size I.D x O.D
End caps for connectors 5001.0050.025 25 1/2" 0.380" x 0.852"
FlatBioEndCap is designed to terminate a
™
5001.0075.025 25 3/4" 0.620" x 0.852"
disposable manifold until a new connection is 5001.0100.025 25 1" 0.877" x 1.984"
to be made. 5001.0150.025 25 1 1/2" 1.377" x 1.984"
»» Provides a reliable, repeatable seal when used in 5001.0200.025 25 2" 1.875" x 2.520"
combination with a gasket and clamp
5001.0250.025 25 2 1/2" 2.374" x 3.050"
»» Traditional flat end cap design to directly replace stainless 5001.0300.025 25 3" 2.878" x 3.583"
steel equivalent
5001.0400.025 25 4" 3.843" x 4.658"
»» Size identification moulded into every component for ease
5001.0600.025 25 6" 5.822" x 6.570"
of use
5001.0800.025 25 8" 7.822" x 8.570"

BioClamp
Part number Pack size Size Max. operating pressure
NG075WHT 10 PCS 1/2" – 3/4" TC 10bar

NG075WHT-100 100 PCS 1/2" – 3/4" TC 10bar

BioClamp continued on page 10

BioClamp, continued BioBarb
Part number Pack size Size Max. operating pressure Part number Pack size Size Max. operating pressure
NG150WHT 10 PCS 1" – 1 1/2" TC 10bar PPMTC0125BB 10 PCS 1/2" – 3/4" TC To 1/8" HB 4bar

NG150WHT-50 50 PCS 1" – 1 1/2" TC 10bar PPMTC0250BB 10 PCS 1/2" – 3/4" TC To 1/4" HB 4bar

NG200WHT 10 PCS 2" TC 10bar PPMTC0375BB 10 PCS 1/2" – 3/4" TC To 3/8" HB 4bar

NG200WHT-50 50 PCS 2" TC 10bar PPMTC0500BB 10 PCS 1/2" – 3/4" TC To 1/2" HB 4bar

NG250WHT 10 PCS 2 1/2" TC 10bar PPMTC0625BB 10 PCS 1/2" – 3/4" TC To 5/8" HB 4bar

NG250WHT-40 40 PCS 2 1/2" TC 10bar PPSTC0125BB 10 PCS 1" – 1 1/2" TC To 1/8" HB 4bar

NG300WHT 10 PCS 3" TC 10bar PPSTC0250BB 10 PCS 1" – 1 1/2" TC To 1/4" HB 4bar

NG300WHT-20 20 PCS 3" TC 10bar PPSTC0375BB 10 PCS 1" – 1 1/2" TC To 3/8" HB 4bar

NG400WHT 5 PCS 4" TC 10bar PPSTC0500BB 10 PCS 1" – 1 1/2" TC To 1/2" HB 4bar

NG400WHT-20 20 PCS 4" TC 10bar PPSTC0625BB 10 PCS 1" – 1 1/2" TC To 5/8" HB 4bar

NG600WHT 5 PCS 6" TC 6bar PPSTC0750BB 10 PCS 1" – 1 1/2" TC To 3/4" HB 4bar

NG800WHT 5 PCS 8" TC 6bar PPSTC0875BB 10 PCS 1" – 1 1/2" TC To 7/8" HB 4bar

PPSTC1000BB 10 PCS 1" – 1 1/2" TC To 1" HB 4bar

Single braided hose
Part number Length m (ft) I.D x O.D mm (inch) Min. burst pressure* bar (psi) BioValve
BPSHP0125-C 7.6 (25) 3.2 (0.125) x 8.8 (0.345) 48.3 (700) Part number Pack size Size Max. operating pressure
BPSHP0188-C 7.6 (25) 4.8 (0.187) x 10.3 (0.407) 44.3 (650) BV0500NW 5 PCS 1/8" – 3/4" OD Tube 10bar

BPSHP0250-C 7.6 (25) 6.4 (0.250) x 12.4 (0.490) 43.1 (625) BV1000NW 5 PCS 1/2" – 1 1/4" OD Tube 10bar

BPSHP0375-C 7.6 (25) 9.6 (0.375) x 16.7 (0.658) 37.9 (550)

BPSHP0500-C 7.6 (25) 12.7 (0.500) x 20.3 (0.800) 34.5 (500)

Bio Y
Part number Pack size Size Max. operating pressure
BPSHP0625-C 7.6 (25) 15.9 (0.625) x 24.5 (0.965) 28.9 (420)
PP0250BY 10 PCS 1/4" HB 4bar
BPSHP0750-C 7.6 (25) 19.0 (0.750) x 27.9 (1.100) 24.1 (350)
PP0375BY 10 PCS 3/8" HB 4bar
BPSHP0875-C 7.6 (25) 22.2 (0.875) x 32.0 (1.260) 20.7 (300)
PP0500BY 10 PCS 1/2" HB 4bar
BPSHP1000-C 7.6 (25) 25.4 (1.00) x 34.5 (1.360) 15.1 (220)
PP0625BY 10 PCS 5/8" HB 4bar
BPSHP0125-D 15.2 (50) 3.2 (0.125) x 8.8 (0.345) 48.3 (700)
PP0750BY 10 PCS 3/4" HB 4bar
BPSHP0188-D 15.2 (50) 4.8 (0.187) x 10.3 (0.407) 44.3 (650)
PP0875BY 10 PCS 7/8" HB 4bar
BPSHP0250-D 15.2 (50) 6.4 (0.250) x 12.4 (0.490) 43.1 (625)
PP1000BY 10 PCS 1" HB 4bar
BPSHP0375-D 15.2 (50) 9.6 (0.375) x 16.7 (0.658) 37.9 (550)

BPSHP0500-D 15.2 (50) 12.7 (0.500) x 20.3 (0.800) 34.5 (500)

BioEndCap
BPSHP0625-D 15.2 (50) 15.9 (0.625) x 24.5 (0.965) 28.9 (420)
Part number Pack size Size Max. operating pressure
BPSHP0750-D 15.2 (50) 19.0 (0.750) x 27.9 (1.100) 24.1 (350)
PEC-500-750 10 PCS 1/2" – 3/4" TC 4bar
BPSHP0875-D 15.2 (50) 22.2 (0.875) x 32.0 (1.260) 20.7 (300)
PEC-100-150 10 PCS 1" – 1 1/2" TC 4bar
BPSHP1000-D 15.2 (50) 25.4 (1.00) x 34.5 (1.360) 15.1 (220)
*at 20C/68F
FlatBioEndCap
Double braided hose
Part number Pack size Size Max. operating pressure
Part number Length m (ft) I.D x O.D mm (inch) Min. burst pressure* bar (psi)
PEC-050-075-FC 10 PCS 1/2" – 3/4" TC 4bar
BPDHP0500-C 7.6 (25) 12.7 (0.500) x 23.9 (0.940) 48.3 (700)
PEC-100-150-FC 10 PCS 1" – 1 1/2" TC 4bar
BPDHP0750-C 7.6 (25) 19.0 (0.750) x 31.8 (1.250) 44.3 (650)
PEC-200-FC 10 PCS 2" TC 4bar
BPDHP1000-C 7.6 (25) 25.4 (1.00) x 36.3 (1.430) 43.1 (325)
PEC-250-FC 10 PCS 2 1/2" TC 4bar
BPDHP0500-D 15.2 (50) 12.7 (0.500) x 23.9 (0.940) 37.9 (550)

BPDHP0750-D 15.2 (50) 19.0 (0.750) x 31.8 (1.250) 34.5 (500)

BPDHP1000-D 15.2 (50) 25.4 (1.00) x 36.3 (1.430) 28.9 (420)

*at 20C/68F
 BIOTECHNOLOGY AND PHARMACEUTICAL SOLUTIONS

Watson-Marlow Fluid Technology Group

Watson-Marlow Fluid Technology Group supports
its customers locally through an extensive global
network of direct sales operations and distributors

wmftg.com/global

H B 04 59 I ss ue 4
Copyright © 2017 Watson-Marlow Fluid Technology Group

Disclaimer: The information contained in this document is believed to be correct but

Watson-Marlow Limited accepts no liability for any errors it contains and reserves the right
to alter specifications without notice. It is the users responsibility to ensure product suitability
for use within their application. Watson-Marlow and puresu are registered trademarks of
Watson-Marlow Limited. Bio Y, BioClamp, BioBarb, FlatBioEndCap, BioEndCap, BioValve and
BioTube applicator are Trademarks of BioPure Technology Limited. Tri-Clamp is a registered
trademark of Alfa Laval Corporate AB. Q-Clamp is used under licence.