FORMOSO, PATRICK JOHN L.
June 11, 2019
BSN 1-G                                                                     BIOCHEMISTRY LECTURE
     Type         Description       Osmolality            Use                    Miscellaneous
                 0.9% NaCl in         Isotonic      Increases             Replaces losses without altering
                 Water              (308 mOsm)      circulating            fluid concentrations.
 Normal Saline   Crystalloid                        plasma volume         Helpful for Na+ replacement
     (NS)        Solution                           when red cells
                                                    are adequate
                 0.45% NaCl in       Hypotonic      Raises total          Useful for daily maintenance of
                 Water              (154 mOsm)      fluid volume           body fluid, but is of less value
                 Crystalloid                                               for replacement of NaCl deficit.
  1/2 Normal
                 Solution                                                 Helpful for establishing renal
  Saline (1/2
                                                                           function.
      NS)
                                                                          Fluid replacement for clients
                                                                           who don’t need extra glucose
                                                                           (diabetics)
                 Normal saline        Isotonic      Replaces fluid        Normal saline with K+, Ca++,
   Lactated      with               (275 mOsm)      and buffers pH         and lactate (buffer)
 Ringer’s (LR)   electrolytes and                                         Often seen with surgery
                 buffer
                 Dextrose 5% in      Isotonic (in   Raises total          Provides 170-200
                 water                 the bag)     fluid volume.          calories/1,000cc for energy.
                 Crystalloid        *Physiologica   Helpful in            Physiologically hypotonic -
                 solution           lly hypotonic   rehydrating            the dextrose is metabolized
     D5W                                            and excretory          quickly so that only water
                                    (260 mOsm)
                                                    purposes.              remains - a hypotonic fluid
                 Dextrose 5% in      Hypertonic     Replaces fluid        Watch for fluid volume overload
                 0.9% saline        (560 mOsm)      sodium,
     D5NS                                           chloride, and
                                                    calories.
                 Dextrose 5% in      Hypertonic     Useful for daily      Most common postoperative
                 0.45% saline       (406 mOsm)      maintenance            fluid
                                                    of body fluids
  D5 1/2 NS
                                                    and nutrition,
                                                    and for
                                                    rehydration.
                 Dextrose 5% in      Hypertonic     Same as LR            Watch for fluid volume overload
                 Lactated           (575 mOsm)      plus provides
     D5LR        Ringer’s                           about 180
                                                    calories per
                                                    1000cc’s.
                 Normosol             Isotonic      Replaces fluid        pH 7.4
                                    (295 mOsm)      and buffers pH        Contains sodium, chloride,
  Normosol-R                                                               calcium,     potassium and
                                                                           magnesium
                                                                          Common fluid for OR and PACU