1/29/2018
ABERROMETRY AND MF IOLS:
WHAT WE CAN LEARN
FRANCESCO CARONES, MD
PHYSICIAN CEO AND MEDICAL DIRECTOR
CARONES OPHTHALMOLOGY CENTER, MILAN, ITALY
FINANCIAL DISCLOSURES
Francesco Carones, MD consults for the following companies:
• Alcon Laboratories (relevant to this presentation)
• CSO (relevant to this presentation)
• Johnson & Johnson Vision (relevant to this presentation)
• Slack (not relevant to this presentation)
• Vivior (not relevant to this presentation)
• WaveLight (not relevant to this presentation)
1
1/29/2018
WAVEFRONT SENSING TECHNOLOGY
• Hartmann-Shack (Autonomous, AMO-VISX)
• Tscherning (WaveLight)
• Slit-lamp scanning skiascopy (Nidek)
• Ray Tracing (Tracey)
• Pyramid Wavefront Sensor (CSO, Schwind)
2
1/29/2018
3
1/29/2018
Relationship Slope and Light Intensity
4
1/29/2018
CSO OSIRIS ABERROMETER
Pyramidal Wavefront Sensor (PWS)
• Spatial resolution:
• 45.000 data point (Ø= 9.0 mm)
(1.500 other technologies)
• 4.500 data point (Ø= 3.0 mm)
(150 other technologies)
• Sensitivity:
• 4096 shades of gray
EXAMPLE: MONOFOCAL IOL, -2.00D
5
1/29/2018
EXAMPLE: MONOFOCAL IOL, -2.00D
Total aberrations
Low order High order
aberrations aberrations
EXAMPLES: PRESBYOPIA-CORRECTION DIFFRACTIVE IOLS
BIFOCAL (ReStor 3.0) TRIFOCAL (PanOptix) EDOF (Symfony)
6
1/29/2018
EXAMPLES: PRESBYOPIA-CORRECTION REFRACTIVE IOLS
Zonal Refractive (ReZoom) Pos/Neg SA (MINIWELL) Segmental Refractive (MPlus)
CLINICAL EVALUATION IN EYES IMPLANTED WITH
PRESBYOPIA-CORRECTING IOLS
120 implanted eyes, 1-12 months after surgery
• 40 Alcon PanOptix (trifocal, diffractive)
• 40 J&J Vision Symfony (EDOF, diffractive echelette)
• 20 Alcon ReSTOR 3.0 (bifocal, diffractive)
• 10 Alcon ReSTOR 2.5 (bifocal, diffractive)
• 10 SIFI MiniWell (EDOF, positive/negative spherical aberration)
7
1/29/2018
MAIN OUTCOMES – CENTRATION
Measurement in relation to the visual axis or center of the pupil
• Impact of decentration on PSF and Simulated Visual Acuity
MAIN OUTCOMES – DIFFRACTIVE PATTERN
Optical design detection in 100% of IOLs
• Central area diameter and focus
• Number of diffractive steps
• Dioptric value of add power
Energy
Distance 1/120 1/60 1/40 1/Focal
0th 1st 2nd 3rd distance
8
1/29/2018
MAIN OUTCOMES – ADD POWER
Measurement of the dioptric range and multifocality
• Dioptric range
• Peak to valley
ReSTOR 3.0 Symfony MiniWell PanOptix
AD INTERIM CONCLUSIONS
The Pyramid Wavefront Sensor (PWS) proved highly sensitive and with a
much higher spatial resolution than the other wavefront sensors
• Much more detailed measurements
• Very useful information
The software needs to be developed as to make all measured information
more user friendly for researchers and clinicians
9
1/29/2018
10