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Anticoagulants Drug Table

Warfarin is an oral anticoagulant used to prevent blood clots like deep vein thrombosis, pulmonary embolism, and strokes. It works by disrupting the coagulation cascade and thinning the blood. Adverse effects include bleeding and monitoring is needed through PT and INR tests. Heparin is an injectable anticoagulant used to prevent and treat conditions like heart attacks, strokes, and blood clots. It works by blocking the conversion of prothrombin to thrombin and fibrinogen to fibrin to prevent clotting. Side effects include bleeding and low platelet counts. Enoxaprin is a low molecular weight heparin given by subcutaneous injection to prevent blood cl

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2K views1 page

Anticoagulants Drug Table

Warfarin is an oral anticoagulant used to prevent blood clots like deep vein thrombosis, pulmonary embolism, and strokes. It works by disrupting the coagulation cascade and thinning the blood. Adverse effects include bleeding and monitoring is needed through PT and INR tests. Heparin is an injectable anticoagulant used to prevent and treat conditions like heart attacks, strokes, and blood clots. It works by blocking the conversion of prothrombin to thrombin and fibrinogen to fibrin to prevent clotting. Side effects include bleeding and low platelet counts. Enoxaprin is a low molecular weight heparin given by subcutaneous injection to prevent blood cl

Uploaded by

Nicole Ho
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© © All Rights Reserved
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BLOOD FORMING DRUGS/ ANTICOAGULANTS:

Prototype: Class: Clinical Use: M.O.A. Adverse Effects: Nursing Implications:

Anticoagulant Prevent: Disrupts coagulation Bleeding PO only! No Pregnancy


Warfarin cascade Diarrhea*, Dermatitis*, Antidote: vitamin K
(Oral) DVT, MI, CVA,
(Coumadin) Thins blood & stops Alopecia* Monitor PT & INR (Daily
TIA, PE, Atrial more clots from forming til stable dose reached)
DOES NOT DISSOLVE **ONLY common to Avoid foods with Vit. K
Fib CLOT. Coumadin**
Anticoagulant Prevention & treatment: Blocks conversion of Injection site reaction** Monitor: PTT, Give
Heparin (Parenteral) CVA, MI, DVT, prothrombin to
thrombin & fibrinogen
Temp low platelet
Thrombocytopenia
subQ or IV, NEVER IM!!
Antidote: protamine
CAD, TIAs, CHF to fibrin Spontaneous bleeding sulfate OK to Use w/
May suppress renal Coumadin & Asprin
function Never give w/
lovenox, penicillin, or
cephalosporins
No post op patients**
low molecular Knee and hip surgery Prevents conversion of Thrombocytopenia Sub Q ONLY! NO LABS**
Enoxaprin Prevent DVT factor Xa to Thrombin Bleeding tendencies Antidote: Protamine
(Lovenox) weight heparin (For Maintenance & Does NOT dissolve the (Less bleeding tendency Sulfate (Rarely needed)
(LMWH) Prevention) clot than Heparin) NEVER GIVE WITH
HEPARIN!!!
Asprin Antiplatelet Aspirin- prevention of Inhibits Platelet Bleeding tendencies** Contraindicated in pts:
& MI aggregation Angioedema, w/ Peptic Ulcer disease
drug Plavix- higher risk pt. bronchospasms, & Post op pts have
clopidogrel Usually already had MI. Thrombocytopenia bleeding tendency.
(Plavix) Monitor labs: CBC, PTT
Acute MI, stroke or limb DISSOLVES CLOTS!!!! **BLEEDING Need CAT scan before
Streptokinase Thrombolytic threatening clot Used ONLY in (Very strong) giving streptokinase b/c
(Streptase) Agent disorder, IV catheter or EMERGENCY!!! Contraindicated for pts if you have clot in brain
Shunts Enzyme from strep with bleeding disorders it will kill you so its
bacteria or if hemorrhagic RARELY USED***

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