By: -
Dhaval Malhotra (07BIC020)                   Bhavya Chauhan (07BIC006)
(Receipt no. 211)                            (Receipt no. 167)
+91-9376124696                               +91-9925388606
malhotradd1990@gmail.com                      bhavya.chauhan@gmail.com
College: Institute of Technology, Nirma University
                            INDEX
Sr.   Topic                                     Pg.
No                                              No
1.    Introduction-The Fundamentals of Nano     3
2.    Applications of Nanotechnology            4
      a) Nanosensors
      b) Nanomedicine
      c) Nanomaterials
      d) Energy Applications
      e) Nanorobots
3.    Dark sides of Nanotechnology              10
4.    Nanotechnology: Earth’s Friend or Foe??   12
      Solving the Dilemma
5.    Bibliography                              13
                               2
               Introduction                               This power, in fact, facilitates the creation of
                                                          all     man   made      products.      That     is
        The Fundamentals of
                                                          nanotechnology!!!
             Nanotechnology
                                                          Nanotechnology, shortened to "Nanotech", is
                                                          the study of the control of matter on an atomic
                                                          and       molecular       scale.       Generally
                                                          nanotechnology deals with structures of the
                                                          size 100 nanometres or smaller, and involves
                                                          developing materials or devices within that
                                                          size.
                                                          "'Nanotechnology' mainly consists of the
                                                          processing of, separation, consolidation, and
                                                          deformation of materials by one atom or by
                                                          one molecule. Two main approaches are used
                                                          in nanotechnology:
Man has learnt a lot from nature. Yet his
                                                          I. Bottom-up Approach
manufacturing     practices     are   primitive.
                                                          II. Top-Down Approach
Everyone knows that a lot more needs to be
                                                          In the "bottom-up" approach, materials and
done to get closer to nature. For example, no
                                                          devices are built from molecular components
one    has    reached     the   efficiency    of
                                                          which assemble themselves chemically by
photosynthesis in storing energy.
                                                          principles of molecular recognition.
No factory does water purification & storage
                                                          In the "top-down" approach, nano-objects are
as efficiently as coconut trees or water
                                                          constructed from larger entities without
melons. The constitution of watermelon is far
                                                          atomic-level control.
more complex than the most complex
integrated circuit, yet it costs far less. On the
other hand, the power to manipulate atoms &
arrange them in the way we please can
facilitate the creation of complex inorganic
structures merely at the price of vegetables.             Applications of Nanotechnology
                                                    III
                                                        Nanosensors are any biological, chemical, or
                                                       surgery sensory points used to convey
While conventional chemistry uses inexact
                                                       information     about    nanoparticles    to     the
processes driven toward some balance to
                                                       macroscopic world. Their uses mainly include
obtain inexact results, and biology exploits
                                                       medicinal purposes. Nanomedicine seeks to
inexact processes to obtain definitive results,
                                                       deliver a valuable set of research tools and
nanotechnology     would     employ    original
                                                       clinically helpful devices in the near future.
definitive   processes   to obtain definitive
                                                       Medicinal uses of nanosensors mainly revolve
results. Nanoparticles can strongly influence
                                                       around the potential of nanosensors to
the mechanical properties of the material, like
                                                       accurately identify particular cells or places in
stiffness or elasticity. With nanotechnology, a
                                                       the body in need. By measuring changes in
large set of materials and improved products
                                                       volume,     concentration,     displacement    and
rely on a change in the physical properties
                                                       velocity,     gravitational,    electrical,    and
when the feature sizes are shrunk. As of
                                                       magnetic forces, pressure, or temperature of
August 21, 2008, the ‘Project on Emerging
                                                       cells in a body, nanosensors may be able to
Nanotechnologies’ estimates that over 800
                                                       distinguish between and recognize certain
manufacturer-identified nanotech products are
                                                       cells, most notably those of cancer, at the
publicly available, with new ones hitting the
                                                       molecular level in order to deliver medicine or
market at a pace of 3-4 per week. Some major
                                                       monitor development to specific places in the
applications of nanotechnology are:
                                                       body[2]. In addition, they may be able to
                                                       detect macroscopic variations from outside the
      Nanosensors
                                                       body and communicate these changes to other
      Nanomedicine
                                                       nanoproducts working within the body. One
      Nanomaterials
                                                       example of nanosensors involves using the
      Energy applications
                                                       fluorescence properties of cadmium selenide
      Nanorobots
                                                       quantum dots as sensors to uncover tumours
                                                       within the body. By injecting a body with
   There are many applications of nano
                                                       these quantum dots, a doctor could see where
   technology; few of them are discussed
                                                       a tumour or cancer cell was by finding the
   here:
                                                       injected quantum dots. A nanosensor probe
                                                       carrying a laser beam (blue) penetrating a
 Nanosensors                                          living cell to detect the presence of a product
                                                  IV
indicating that the cell has been exposed to a           Nanomedicine
cancer-causing substance is shown in the                Nanomedicine is the medical application of
image.                                                  nanotechnology.      The      approaches       to
                                                        nanomedicine range from the medical use of
                                                        nanomaterials, to nanoelectronic biosensors,
                                                        and even possible future applications of
                                                        molecular nanotechnology. Nanomedicine is a
                                                        large industry, with nanomedicine sales
                                                        reaching 6.8 billion dollars in 2004, and with
                                                        over   200   companies     and      38   products
                                                        worldwide, a minimum of 3.8 billion dollars
                                                        in nanotechnology R&D is being invested
                                                        every year. As the nanomedicine industry
Other applications except medicinal using               continues to grow, it is expected to have a
nanosensors are building smaller integrated             significant impact on the economy.
circuits, as well as incorporating them into
various other commodities made using other
                                                         Drug delivery
forms of nanotechnology for use in a variety
                                                        Bioavailability refers to the presence of drug
of   situations   including       transportation,
                                                        molecules where they are needed in the body
communication, improvements in structural
                                                        and where they will do the most good. Drug
integrity, and robotics. Nanosensors may also
                                                        delivery      focuses      on         maximizing
                       eventually be valuable as
                                                        bioavailability both at specific places in the
                       more accurate monitors
                                                        body and over a period of time. This will be
                       of material states for use
                                                        achieved     by   molecular        targeting   by
                       in systems where size
                                                        nanoengineered devices. It is all about
                       and      weight       are
                                                        targeting the molecules and delivering drugs
constrained, such as in satellites and other
                                                        with cell precision. Drug delivery systems,
aeronautic machines.
                                                        lipid- or polymer-based nanoparticles, can be
                                                        designed to improve the pharmacological and
                                                        therapeutic properties of drugs.
                                                    V
 Surgery                                                 Cancer Treatment
A flesh welder is used to fuse two pieces of             The small size of nanoparticles endows them
chicken meat into a single piece. The two                with properties very useful in curing cancer.
pieces   of   chicken     are   placed   together        Quantum dots (nanoparticles with quantum
touching. A greenish liquid containing gold-             confinement properties, such as size-tunable
coated nanoshells is dribbled along the seam.            light emission), when used in conjunction with
An infrared laser is traced along the seam,              MRI (magnetic resonance imaging), can
causing the two sides to weld together. This             produce exceptional images of tumour sites.
could solve the difficulties and blood leaks             How nanotechnology can be used in cancer
caused when the surgeon tries to restitch the            treatment is shown in the figure.
arteries he/she has cut during a kidney or heart
                                                         Nanorobots are also used in medical field.
transplant. The flesh welder could meld the
                                                         Their applications are discussed in later part.
artery into a perfect seal.
                                                    VI
 Nanomaterials
One proposed application of MNT is the
development of so-called smart materials.
This term refers to any sort of material
designed and engineered at the nanometre
scale to perform a specific task, and
encompasses a wide variety of possible
commercial applications. One example would
be materials designed to respond differently to
various molecules; such a capability could
lead, for example, to artificial drugs which
would recognize and render inert specific
viruses. Another is the idea of self-healing
structures, which would repair small tears in a            magnetic,    optical,   chemical      and   other
surface naturally in the same way as self-                 properties. Nanoparticles have been used as
sealing tires or human skin.                               quantum dots and as chemical catalysts. When
                                                           materials are made into nanoparticles, their
Materials referred to as "nanomaterials"                   surface area to volume ratio increases. The
generally fall into two categories: Fullerenes             greater specific surface area (surface area per
and Inorganic nanoparticles.                               unit weight) may lead to increased rate of
                                                           absorption   through    the   skin,   lungs, or
Fullerenes are under study for potential                   digestive tract and may cause unwanted
medicinal use: binding specific antibiotics to             effects to the lungs as well as other organs.
the structure of resistant bacteria and even               However, the particles must be absorbed in
target certain types of cancer cells such as               sufficient quantities in order to pose health
melanoma. They are also used as light-                     risks. Nanomaterials behave differently than
activated antimicrobial agents.                            other similarly-sized particles. It is therefore
                                                           necessary to develop specialized approaches
Nanoparticles or nanocrystals made of metals,              to testing and monitoring their effects on
semiconductors, or oxides are of particular                human health and on the environment.
interest   for   their   mechanical,   electrical,
                                                     VII
 Energy Applications                                  Increasing the efficiency of energy
                                                          production
Over the past few decades, the fields of              Today's best solar cells have layers of several
science and engineering have been seeking to          different semiconductors stacked together to
develop new and improved types of energy              absorb light at different energies but they still
technologies that have the capability of              only manage to use 40 percent of the Sun's
improving life all over the world. In order to        energy. Commercially available solar cells
make the next leap forward from the current           have much lower efficiencies (15-20%).
generation of technology, scientists and              Nanotechnology could help increase the
engineers have been developing Energy                 efficiency of light conversion by using
Applications of Nanotechnology. The most              nanostructures with a continuum of bandgaps.
advanced nanotechnology projects related to           The degree of efficiency of the internal
energy       are:         storage,     conversion,    combustion engine is about 30-40% at the
manufacturing improvements by reducing                moment.     Nanotechnology      could     improve
materials and process rates, energy saving (by        combustion by designing specific catalysts
better thermal insulation for example), and           with maximized surface area. In 2005,
enhanced renewable energy sources.                    scientists at the University of Toronto
                                                      developed a spray-on nanoparticle substance
 Reduction of energy consumption                     that, when applied to a surface, instantly
A reduction of energy consumption can be              transforms it into a solar collector.
reached by better insulation systems, by the
use of more efficient lighting or combustion           The use of more environmentally friendly
systems, and by use of lighter and stronger              energy systems
materials   in      the    transportation   sector.
Currently used light bulbs only convert               An example for an environmentally friendly
approximately 5% of the electrical energy into        form of energy is the use of fuel cells powered
light.   Nanotechnological       approaches    like   by hydrogen, which is ideally produced by
light-emitting diodes (LEDs) or quantum               renewable    energies.    Probably      the   most
caged atoms (QCAs) could lead to a strong             prominent nanostructured material in fuel cells
reduction    of     energy      consumption    for    is the catalyst consisting of carbon supported
illumination.                                         noble metal particles with diameters of 1-5
                                                      nm. Suitable materials for hydrogen storage
                                                  VIII
contain a large number of small nanosized
pores.       Therefore        many       nanostructured
materials like nanotubes, zeolites or alanates
are under investigation. Nanotechnology can
contribute      to     the    further    reduction     of
combustion engine pollutants by nanoporous                       application is the detection of toxic chemicals,
filters,     which      can    clean      the     exhaust        and the measurement of their concentrations,
mechanically, by catalytic converters based on                   in the environment.
nanoscale noble metal particles or by catalytic
coatings on cylinder walls and catalytic
nanoparticles as additive for fuels.
                                                                 Some other general purpose applications of
 Recycling of batteries                                         Nanotechnology        &   nanomaterials      are
Because of the relatively low energy density                     discussed below:
of batteries the operating time is limited and a                    Memory Storage
replacement or recharging is needed. The huge                       Novel semiconductor & optoelectronic
number of spent batteries and accumulators                           Devices
represent a disposal problem. The use of                            Quantum computers
batteries with higher energy content or the use                     Strong materials for constructions
of rechargeable batteries or supercapacitors
                                                                    Production, Processing, safety and
with       higher     rate    of   recharging       using
                                                                    Packaging of food
nanomaterials could be helpful for the battery
                                                                    Consumer Goods in textiles, optics etc
disposal problem.
                                                                    Self-cleaning or “easy-to-clean” surfaces
                                                                     & scratch resistant surface coatings
 Nanorobots
The first useful application of nanorobots is in
medical technology, where they might be used
to identify cancer cells and destroy them.
Nanorobots           make     possible      the     rapid
elimination of disease and the reliable and
relatively painless recovery. Another potential
                                                            IX
 Dark Side of Nanotechnology                           nanoelectronics-based sensors are another
                                                        active goal of research. The speculative field
                                                        of molecular nanotechnology believes that cell
Risks include environmental, health, safety             repair machines could revolutionize medicine
issues. Potential risks of nanotechnology can           and the medical field.
broadly be grouped into four areas:
                                                         Environmental issues
 Health issues
                                                              (Nanopollution)
These are the effects of nanomaterials on
                                                        All waste generated by nanodevices or during
human biology due to surface reactivity with
                                                        the    nanomaterials     manufacturing    process
the surrounding tissue. The extremely small
                                                        creates environmental problems. This kind of
size of nanomaterials means that they are
                                                        waste may be very dangerous because of its
much more readily taken up by the human
                                                        size. It can float in the air and might easily
body than larger sized particles. These non-
                                                        penetrate animal and plant cells causing
degradable or slowly degradable nanoparticles
                                                        unknown effects.
accumulate in organs. Another concern is their
potential interaction with biological processes
                                                        On the other hand, some possible future
inside the body; because of their large surface,
                                                        applications     of      nanotechnology      like
nanoparticles on exposure to tissue and fluids
                                                        Nanofiltration ( suitable for a mechanical
will immediately adsorb onto their surface
                                                        filtration for the removal of ions or the
some of the macromolecules they encounter.
                                                        separation of different fluids), removal of
The large number of variables influencing
                                                        heavy metal contaminants from waste water
toxicity means that it is difficult to generalise
                                                        using magnetic nanoparticles, clean energy
about health risks associated with exposure to
                                                        production by using nanomaterials for more
nanomaterials – each new nanomaterial must
                                                        efficient solar cells, practical fuel cells,
be assessed individually and all material
                                                        environmentally-friendly batteries etc can not
properties must be taken into account. . But
                                                        be overlooked.
on the other side Nanomedicine seeks to
deliver a valuable set of research tools and
                                                         Social issues
clinically helpful devices in the near future
                                                        These are the effects that the availability of
applications   like   vivo   imaging.    Neuro-
                                                        nanotechnological      devices   will have on
electronic      interfaces       and       other
                                                    X
politics and human interaction. Many social               Grey goo
scientists and organizations in civil society            Grey goo is a hypothetical end-of-the-world
suggest that technology assessment should be             scenario involving molecular nanotechnology
done and governance should also involve
public participation to raise societal risks from
the use of nanotechnology.
On the instrumental level, these include the
                                                         in which out-of-control self-replicating robots
                                                         consume all matter on earth while building
                                                         more of themselves. The disaster is posited to
                                                         result from a deliberate doomsday device or
                                                         from an accidental mutation in a self-
                                                         replicating nanomachine used only for other
possibility   of   military   applications    of         purposes, but designed to operate in a natural
nanotechnology (for instance, as in implants             environment.
and other means for soldier enhancement like
those being developed at the Institute for
Soldier Nanotechnologies at MIT [3]) as well
as enhanced surveillance capabilities through
nano-sensors.
On    the     structural   level,   critics   of
nanotechnology point to a new world of
ownership and corporate control opened up by
nanotechnology.
                                                    XI
 Solving The Dilemma                                       Nanotechnology could potentially have a great
                                                            impact      on     clean        energy        production.
Every coin has two sides. One may be the                    Nanomaterials can be used for purposes
dark one & another may be the bright one. But               including more efficient solar cells, practical
it depends on us how we take the problem.                   fuel     cells,   and        environmentally-friendly
Nanotechnology on one hand serves a great                   batteries. Filtration of water using magnetic
impact to human being & nature and on the                   nano-particles is far more efficient than any
other hand it creates hazardous effects on                  other method of filtration, thereby decreasing
environment if not treated properly.                        water pollution. Nanomedicines seek to
The mere presence of nanoparticles is not                   deliver a valuable set of research tools and
itself a threat but its increased mobility & its            clinically helpful devices in the near future.
high reactivity can cause hazardous effects to              Cell     repair   machines,           using    molecular
living beings & environment, if exposed                     nanotech, can revolutionize medicine &
directly. Again according to "Centre For                    medical field. Clean and highly efficient
Responsible    Nanotechnology",        'Molecular           manufacturing is possible by the use of
manufacturing allows the cheap creation of                  nanotechnology. Atomically engineered food
incredibly powerful devices and products.                   and crops resulting in greater agricultural
The range of possible damage is vast, from                  productivity with less labour requirements is
personal    low-flying   supersonic        aircraft         also possible by the use of nanotech.
injuring   large   numbers      of   animals    to          Hence      just   because        of     some      of     the
collection of solar energy on a sufficiently                implications of nanotech we can’t discard it.
large scale to modify the planet's albedo and               We should take the steps to solve those
directly affect the environment. Stronger                   implications by setting the laws for the use of
materials will allow the creation of much                   nanotechnology          on     large     scale.        Since
larger machines, capable of excavating or                   evolution of mankind always creates small to
otherwise destroying large areas of the planet              big impacts on nature, we should try to
at a greatly accelerated pace.' Thus nanotech               obstruct these shortcomings by taking the
can create problems to environment. These                   preventive steps, & not by obstructing the
may be taken as major implications of                       whole technology. Otherwise the time will
nanotechnology.    But   that    doesn’t     mean           leave us behind it. Hence to conclude
nanotechnology is totally harmful to nature.                nanotech is the friend of earth, if it is used for
                                                            the promotion of mankind & nature.
                                                      XII
 Bibliography
      Nanotechnology                      and
    Nanoelectronics :                                    Introduction       to   Nanoscience   and
    Materials, Devices, Measurement                        Nanotechnology
    Techniques                                             By Gabor L. Hornyak, H.F. Tibbals,
    By Fahrner, W.R. (Ed.)                                 Joydeep Dutta
 Nanotechnology: Ethics and Society                     www.wikipedia.org
    By Bennett-Woods                                     www.google.com
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                                                 XIII