Goats: vaccination
programme
Goats are susceptible to a number
of diseases. This programme is
only an indication of the type of
vaccinations that should or can
be given to goats. To determine
if it is necessary to use a specific
vaccine various factors have to
be taken into account, such as
area, the diseases which occur in
your area and the management
system. Whether the animals are
kept in intensive farming systems
is another important consideration.
Consult your local veterinarian if
you have questions about specific
vaccinations.
Vaccination programme
 Month                     Essential vaccines       Optional vaccines
 January
 Kids (4–5 months 	 •	 Epididymitis (male goats)	 •	 Quarter evil 	
 of age)		 (Brucella melitensis)		 (1st inoculation)
 Weaning	 •	 Enterotoxaemia	 •	 Botulism
 		 (oil vaccine)		 (1st inoculation)	
 Adult animals			 •	 Anthrax (in areas where
 				 the disease occurred in
 				 the last 5 years)
 February
 Adult animals	     •	 Enzootic abortion	           •	 Blue udder
 (4–6 weeks before		 (Chlamydia)	                   •	 Wesselbron disease*
 breeding season)			                                •	 Rift Valley fever
 Kids 	            •	 Enterotoxaemia	 •	 Rift Valley fever
 (5–6 months old)		 (oil vaccine)	    •	 Wesselbron disease*
 			                                  •	 Quarter evil
 				 (2nd inoculation)
 			                                  •	 Botulism (2nd inoculation)
 			                                  •	 Anthrax (only if disease
 				 occurred in the area for
 				 the last 5 years)
 March
 From 15 March
 breeding season
 April/May
 All animals			                                     •	 Botulism
 			                                                •	 Pasteurella
 			                                                •	 Quarter evil
*If not immunised before
                                      ——
Month                   Essential vaccines              Optional vaccines
June
Adult animals	          •	 Tetanus (if kids are castrated	 •	 Blue udder
(not immunised before)		 using rubber ring)		 (1st inoculation)
(6–8 weeks before		 (1st inoculation)
kidding)	               •	 Vitamins A, D, E
All animals	            •	 Deworm
July
Adult animals	          •	 Tetanus (if kids are castrated	 •	 Blue udder
(not immunised before)		 using rubber ring)		 (2nd inoculation)
(2–4 weeks before 		 (2nd inoculation)
kidding)	               •	 Vitamins A, D, E
	                       •	 Pasteurella
Adult animals	          •	 Tetanus
(2–4 weeks before	      •	 Pasteurella
kidding)
August
Kids			          •	 Pasteurella
(2 weeks old)			 •	 Vitamins A, D, E
			              •	 Heartwater (in heartwater
				 area)
September
All animals	            •	 Enterotoxaemia (alum)	       •	 Pasteurella
	                       •	 Deworm
Kids			                                                 •	 Pasteurella
(6 weeks old)
October
All animals	            •	 Deworm
                                     ——
Remarks
•	 Bluetongue rarely occurs in goats as severely as it does in sheep, and
   therefore is not mentioned in the list.
•	 Rift Valley fever and Wesselbron disease are rainfall related (distributed
   by mosquitoes) and animals should only be vaccinated if these
   conditions occur. These diseases can result in heavy losses.
•	 Lamb dysentery does not often occur in goats and vaccination is
   therefore not mentioned.
•	 Pasteurella is stress related, caused by adverse weather conditions,
   weaning and change of diet. The animals should be vaccinated
   preferably 2 months before a possible stressful time.
Diseases
 Enterotoxaemia
 (Pulpy kidney/bloednier)
 Cause:	          Clostridium perfringens, also known as Clostridium welchii type D
 	                (bacterium)
 Symptoms:	       •	   Acute death of animals.
 	                •	   Laboured breathing, salivation, diarrhoea.
 	                •	   Twitching muscles, rolling eyes, grinding of teeth.
 	                •	   Many animals in one herd (herd problem).
 Treatment:	      Unsuccessful, because disease is noticed too late.
 Prevention:	 •	       Vaccinate all animals according to the vaccination programme.
 	            •	       Kids are vaccinated 2 times with an interval of 4–6 weeks.
 	            •	       Adults are vaccinated annually.
 	            •	       Do not make sudden changes in diet, grazing or deworming.
 	            •	       Vaccinate at least 3 weeks before deworming.
 	            •	       In a severe outbreak you may consider treating all animals once
 		                    with a long-acting tetracycline.
                                            ——
Pasteurella
(Pasteurellosis/infectious pneumonia/harslagsiekte)
Cause:	          Pasteurella haemolytica and Pasteurella multocida (bacterium)
Symptoms:	 •	      Acute death of animals.
	          •	      Fever, lack of appetite, rapid breathing.
	          •	      Coughing, loss of condition, difficult breathing, discharge from nose
		                 and eyes.
	          •	      Animals lie down with neck stretched out.
Treatment:	      Inject with sulpha or oxytetracycline (Sulphatrim or Liquamycin L A).
Prevention:	 •	    Vaccinate all animals according to vaccination programme. The
		                 vaccine does not give complete protection, therefore cases of
		                 pasteurella can still occur.
	            •	    Kids are vaccinated 2 times with an interval of 4–6 weeks, with an
		                 oil vaccine.
	            •	    Adults are vaccinated annually with an alum vaccine.
	            •	    This disease is stress related. Make sure animals are protected
		                 against possible stress: weather, weaning, scarcity of feed, etc.
Epididymitis
(Brucellosis)
Cause:	          Brucella ovis (bacterium)
Symptoms:	       •	 At first swelling of the testes, later only a hard area in the testes.
	                •	 Leads to infertility of the males.
Treatment:	      •	 No treatment.
	                •	 Infected animals should be removed from the herd.
Prevention:	     •	 Vaccination of male goats at weaning.
	                •	 Males should be tested for diseases before introduction into a herd.
	                •	 Do not vaccinate female goats, this may cause abortion.
                                          ——
Enzootic abortion
(Chlamydiosis)
Cause:	             Chlamydia psittaci (bacterium).
Symptoms:	          •	 Low kidding percentage.
	                   •	 Abortion in later stage of pregnancy.
	                   •	 Weak lambs.
Treatment:	         •	 No treatment.
	                   •	 Infected animals should be removed from the herd.
Prevention:	        Vaccination of all animals before annual breeding season.
Rift Valley fever
(Enzootic hepatitis/RVF)
Cause:	             Bunyavirus
Symptoms:	          •	 Acute death of kids.
	                   •	 Kids show fever, tremors and weakness, adults abort.
Treatment:	         No treatment.
Prevention:	        •	 Vaccination (once per animal, lifelong immunity).
	                   •	 Vaccination together with that for Wesselbron disease.
Wesselbron disease
Cause:	             Flavivirus
Symptoms:	          •	 Acute death of kids, not as acute as in RVF.
	                   •	 Kids show fever, tremors and weakness, adults abort.
Treatment:	         No treatment.
Prevention:	        •	 Vaccination (lifelong immunity).
	                   •	 Vaccination together with that for Rift Valley fever.
	                   •	 These two diseases are difficult to distinguish.
                                            ——
Heartwater
(Rickettsiosis/hartwater)
Cause:	           Cowdria ruminantium (Rickettsia)
Symptoms:	 •	       Loss of appetite, listlessness, rapid breathing.
	          •	       Followed by muscular tremors, circular movements, grinding of
		                  the teeth.
	          •	       Recovering animals show diarrhoea.
	          •	       Immune animals show a slight fever.
Treatment:	 •	 Treatment should occur as early as possible (preferably before
		 the nervous symptoms occur).
	           •	 Oxytetracycline (Liquamycin L A).
Prevention:	 •	     Vaccination after 2 weeks of age may cause severe disease reaction,
		                  therefore end treatment on day 8 or 9 with long-acting tetracycline in
		                  a lower dose than prescribed.
	            •	     Eliminate transmission (the bont tick) by dipping.
	            •	     Do not import animals from a heartwater-free area into a heartwater
		                  area without vaccination.
Blackquarter
(Quarter evil/Black leg/sponssiekte)
Cause: 	          Clostridium chauvoei (bacterium)
Symptoms:	 •	       Fever, loss of appetite, stiffness and swelling of affected area.
	          •	       Initially the swelling is hot and painful, but soon becomes cold
		                  and painless.
	          •	       Overlying skin becomes dark.
	          •	       Death occurs within 24–36 hours.
Treatment:	       •	 Early treatment is necessary, as soon as fever occurs.
	                 •	 Treat with penicillin or oxytetracycline (usually unsuccessful).
Prevention:	 •	     Vaccination, twice at about weaning age, repeat annually.
	            •	     Disease is almost always result of infection of a wound, management
		                  practices (castrating, etc.) and environmental causes (steekgras,
		                  thornbushes, etc.).
	            •	     Hygiene is very important.
	            •	     Destruction of carcasses by burning.
                                          ——
Botulism
(Lamsiekte/gallamsiekte)
Cause:	          Clostridium botulinum (bacterium)
Symptoms:	       •	   Stiffness of the limbs (noticed in leg and neck muscles).
	                •	   Followed by partial or complete paralysis of all muscles.
	                •	   Tongue may protrude.	
	                •	   In less acute cases, animals have difficulty feeding and drinking.
Treatment:	      No treatment.
Prevention:	 •	       Vaccination (especially if animals are fed with chicken litter), twice at
		                    about weaning age, repeat annually.
	            •	       Destroy all carcasses.
	            •	       Bacteria form spores which occur in the soil. Make sure animals
		                    do not suffer from mineral deficiency and show signs of pica.
Blue udder
(Blue bag)
Cause:	          Staphylococcus areus or Pasteurella haemolytica (bacterium)
Symptoms:	 •	         Occur in female goats soon after kidding or even before.
	          •	         Udder becomes infected, swollen and painful, later it turns purple
		                    to blue.
	          •	         Loss of appetite and fever, milk is abnormal and may cause death
		                    of kid(s).
	          •	         Toxins produced by the bacteria cause general disease signs and
		                    eventually death.
Treatment:	      •	 Difficult and costly to treat.
	                •	 Penicillin or oxytetracycline.
Prevention:	 •	       Hygiene.
	            •	       Vaccination, animals that have not been immunised before are given
		                    two vaccinations, 6–8 weeks and 2–4 weeks before kidding.
		                    Repeat annually.
                                           ——
Anthrax
(Miltsiekte)
Cause:	          Bacillus anthracis (bacterium)
Symptoms:	 •	 Acute death without any symptoms.
	          •	 High fever, shivering and trembling, sometimes diarrhoea.
	          •	 Rapid bloat and decomposing of the carcass. Rigor mortis does not
		 occur.
	          •	 After death blood appears at the natural openings (nose, anus, etc.).	
	             NEVER
           NEVER       OPEN
                    OPEN   THETHE   CARCASS!!
                                 CARCASS!!   ThisThis
                                                   will will spread
                                                        spread       the disease.
                                                                the disease.
Treatment:	      No treatment. Disease is noticed too late.
Prevention:	 •	    Vaccination if there are known cases in the area for the last 5 years.
	            •	    Vaccination at weaning, 5 to 6 months of age, repeat annually.
		                 Bury and burn carcass to prevent spread of the disease.
	            •	    Prevent animals from grazing near the infected areas.
	                 NOTIFY
                 NOTIFY   THE
                        THE   STATE
                            STATE   VETERINARIAN!
                                  VETERINARIAN.
    Caseous lymphadenitis
Cheesy gland disease/pseudotuberculosis/absesse
Cause:	          Corynebacterium ovis
Symptoms:	       Development of one or more abscesses in the lymphatic glands.
Treatment:	      Open mature abscess with a clean scalpel or knife on a soft spot.
	                Squeeze the pus out of the abscess and collect it in a tin or plastic
	                bag (do not leave it lying around). Rinse the empty abscess with
	                hydrogen peroxide. Fill the empty abscess with a disinfectant cream
	                and spray with a disinfectant. Inject the animal with penicillin to
	                prevent secondary infection.
Prevention:	 •	 Vaccination repeated every 6 months (not very successful, treatment
		 of the disease might be more economical).
	            •	 Does not provide complete cover. The disease might still occur.
                                        ——
 Tetanus
(Lock-jaw/klem-in-die-kaak)
Cause:	           Clostridium tetani (bacterium).
Symptoms:	 •	       Muscular stiffness, noticeable in neck and legs.
	          •	       Animal cannot eat or drink.
	          •	       Sensitive to any light touch, sharp noise or bright light.
	          •	       Animal may lie down on its side with stiff limbs stretched out and
		                  off the ground.
Treatment:	       •	 Treat the animal with penicillin.
	                 •	 Keep animal in a dark, quiet place.
Prevention:	 •	     Vaccination, twice, a month apart before kidding, then annually
		                  1 month before kidding.
	            •	     Disinfecting of any wounds (castration, etc.).
	            •	     Do not use elastic bands for castration.
                     For further information contact the
              ARC-Animal Nutrition and Animal Products Institute
                        Private Bag X2, Irene 1675
                              Tel: 012 672 9305
                                            or
              the Boer Goat Breeders’ Association of South Africa
                       Tel: 042 43 2130 or 042 243 2130
                                            or
                   Döhne Agricultural Development Institute
                              Tel: 043 63 1240
                                        — 10 —
 This publication is available on the web at: www.nda.agric.za/publications
2007	   Third print
2003	   Second print
1998	   First print
Compiled by
       Directorate Agricultural Information Services, Department of Agriculture
       in cooperation with the Boer Goat Breeders’ Association of South Africa and
       Döhne Agricultural Development Institute
Printed and published by
        Department of Agriculture
Obtainable from
       Resource Centre, Directorate Agricultural Information Services
       Private Bag X144, Pretoria, 0001 South Africa