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Rajiv Gandhi University of Health Sciences, Karnataka: Q.P. CODE: 2604

This document is an exam for a Pharmaceutical Organic Chemistry course. It contains questions that assess students' understanding of organic chemistry concepts. The long essay questions require discussing the mechanism of electrophilic aromatic substitution and Bayer's strain theory. The short essay questions cover topics like the basicity of amines, SN1 reaction mechanism, and Beckmann rearrangement. The short answer questions require defining and explaining terms such as functional isomerism, carbocations, hyperconjugation, and tautomerism. Students must also name structures, differentiate bond types, and give examples of organic chemistry reactions and concepts.

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VISHNU RAJ V
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273 views1 page

Rajiv Gandhi University of Health Sciences, Karnataka: Q.P. CODE: 2604

This document is an exam for a Pharmaceutical Organic Chemistry course. It contains questions that assess students' understanding of organic chemistry concepts. The long essay questions require discussing the mechanism of electrophilic aromatic substitution and Bayer's strain theory. The short essay questions cover topics like the basicity of amines, SN1 reaction mechanism, and Beckmann rearrangement. The short answer questions require defining and explaining terms such as functional isomerism, carbocations, hyperconjugation, and tautomerism. Students must also name structures, differentiate bond types, and give examples of organic chemistry reactions and concepts.

Uploaded by

VISHNU RAJ V
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
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Rajiv Gandhi University of Health Sciences, Karnataka

I Year B.Pharm Degree Examination – NOV 2016


Time: Three Hours Max. Marks: 70 Marks
PHARMACEUTICAL ORGANIC CHEMISTRY – I
(Revised Scheme 3)
Q.P. CODE: 2604
Your answers should be specific to the questions asked
Draw neat labeled diagrams wherever necessary
LONG ESSAYS (Answer any Two) 2 x 10 = 20 Marks
1. Discuss the mechanism of electrophilic aromatic substitution reaction taking a suitable
example. Discuss the theory of reactivity.
2. Write briefly on:
a) Bayer’s strain theory
b) Mechanism for free radical chain reactions of alkane
3. Outline the accepted mechanism with an example.
(a) Perkin’s reaction
(b) Cannizzaro’s reaction

SHORT ESSAYS (Answer any Six) 6 x 5 = 30 Marks


4. Explain basicity of amines.
5. Write the reactions of benzenediazonium chloride.
6. Write the mechanism and stereochemistry of SN1 reaction.
7. Write mechanism and orientation of dehydration of alcohols.
8. Explain the mechanism involved in Beckmann’s rearrangement.
9. What happens when 1,3-butadiene is treated with HBr? Discuss the mechanism.
10. What is electrophilic addition? Explain the mechanism of E 2 and E1 reaction.
11. Discuss the effects of substituents on the acidity of carboxylic acids.

SHORT ANSWERS 10 x 2 = 20 Marks


12. What is functional isomerism? Explain using a suitable example.
13. Differentiate between homolytic and heterolytic fission of a covalent bond.
14. Explain the term carbocation with an example.
15. With a suitable example, explain Freund’s method to prepare cycloalkane.
16. Write the structure and IUPAC name of
a) Picric acid
b) Neopentyl chloride.
17. Define hyperconjugation with an example.
18. What is esterfication? Give an example.
19. Define activating and deactivating group with example.
20. Explain heat of hydrogenation and its significance.
21. Add a note on tautomerism.
*****

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