The BRP Cattle and Sheep

Parasite Control Product Guide

A comprehensive list of products for the control of
internal and external parasites in cattle and sheep

2016
Introduction

Parasite Control – getting it right Administering wormers (anthelmintics) relate to the length of activity of a product (this will be

Choosing the right product and getting the most from it are key
effectively shown elsewhere on the label)

factors in ensuring optimum livestock performance for least When using any medicine or vaccine it is important to read the • Do not mix different wormers together or with other
cost and reducing the risk of anthelmintic resistance. product label and package insert to ensure you understand how products as this can inactivate active ingredients

The aim of this booklet is to provide an accurate, easy-to-use it needs to be administered to the animal. If you do not
reference guide on all available anti-parasitic products in their understand anything or need further information, ask your
various chemical groups and summarising the parasites that veterinary surgeon or SQP.
they have been licensed to control. Decisions on the choice of • Choose the most appropriate product for the parasites
product should be discussed with your advisor, vet, Suitable likely, or known, to be present
Qualified Person (SQP) or Veterinary Pharmacologist (VP). • Store wormers in accordance with instructions, usually away
from direct sunlight, avoiding extremes of temperature and
What type of wormer should be used? keep in a fridge if appropriate
Anthelmintics (wormers) are used to treat and prevent parasite • Always read the label before using all products to check that
infections – roundworm, tapeworm, lungworm and liver fluke. it is suitable for the livestock you want to treat and note
These products fall into the following groups: any precautions for its use

1. (BZ) Benzimidazoles • Only use a product before its expiry date

• Make sure the dosing equipment is compatible with the Before using any product, even if you have used it before, read
2. (LV) Levamisole (Imidazothiazoles)
product that you are using and check it is clean and the product information on the packaging and/or the leaflet
3. (ML) Macrocyclic lactones, including avermectins inside the pack.
measuring the correct volume
and milbemycins
• Administer product according to the manufacturer’s For more information consult the ‘data sheet’ or the ‘summary of
4. (AD) Amino acetonitrile derivatives (Monepantel) product characteristics’ (SPC), which contain additional details and
instructions, paying particular attention to specific methods
5. (SI) Spiro-indoles (Derquantel available as a Multi-active) for ear injections and intra-ruminal boluses any recent changes to specifications, such as withdrawal periods.
Anthelmintics belonging to these groups are active against the • Dose according to liveweight, as detailed in the Data sheets can be found on www.noahcompendium.co.uk and
major species of gut roundworms and lungworms. Some will manufacturer’s instructions SPCs on www.vmd.defra.gov.uk manufacturers can be contacted
also have activity against liver fluke and tapeworms. ML’s directly if these sources do not provide the information you are
• Ideally all cattle should be weighed individually using scales or
(Group 3) injectables and pour-ons also have activity against seeking.
a weigh band to ensure they are dosed accordingly to
some ectoparasites.
liveweight. However, if a group of well-matched cattle are to For further information on treating dairy cows contact
Other products are more specific in the parasites they will kill, be treated together, then it is acceptable to weigh a sample of AHDB Dairy at dairy.ahdb.org.uk or call 0247 669 2051.
ie narrow spectrum. Most anthelmintics in this category are animals and then treat the group according to this estimate
active against liver fluke or ectoparasites.
• Record all wormer products administered (batch number,
Choosing the most appropriate product for the parasites likely, amount and expiry date), animal identity, treatment dates
or known, to be present is vital. Targeting the right parasite will and withdrawal periods accurately
give predictable results and may mean re-treatment is less
• Note withdrawal periods for milk and meat and ensure they
likely to be needed. This may also reduce unnecessary selection
are adhered to. Be aware that withdrawal periods do not www.cattleparasites.org.uk www.scops.org.uk
pressure for anthelmintic resistance.
 Treatments for cattle parasite control – Cattle Endoparasiticides

1-BZ Group 1: Benzimidazoles (BZ) (White)

2-LV 3-ML 4-AD 5-SI

COMPANY CHEMICAL PARASITES CONTROLLED TRACE WITHDRAWAL Milk

PRODUCT USE
NAME NAME Roundworm Lungworm Tapeworm Liver fluke Mites Warbles Lice Hornflies Eyeworm ELEMENTS PERIOD (MEAT) withhold

Albacert Downland Albendazole Yes Yes Yes Yes (adult only) No No No No No Oral Drench Co, Se 14 days 60 hrs
Albenil 2.5% Oral Suspension Virbac Albendazole Yes Yes Yes Yes (adult only) No No No No No Oral Drench Co, Se 14 days 60 hrs
Albex 10% Oral Suspension Chanelle AH Albendazole Yes Yes Yes Yes (adult only) No No No No No Oral Drench 14 days 60 hrs
Albex 2.5% SC Oral Suspension Chanelle AH Albendazole Yes Yes Yes Yes (adult only) No No No No No Oral Drench Co, Se 14 days 60 hrs
Autoworm Finisher Zoetis Oxfendazole Yes Yes Yes No No No No No No Pulse release bolus 6 months X
Autoworm First Grazer Zoetis Oxfendazole Yes Yes Yes No No No No No No Pulse release bolus 8 months X
Bovex 2.265% Chanelle AH Oxfendazole Yes Yes Yes No No No No No No Oral Drench 19 days 84 hrs
Endospec 2.5% SC Bimeda Albendazole Yes Yes Yes Yes (adult only) No No No No No Oral Drench Co, Se 14 days 60 hrs
Endospec 10% SC Bimeda Albendazole Yes Yes Yes Yes (adult only) No No No No No Oral Drench Co, Se 14 days 60 hrs
Panacur Bolus MSD AH Fenbendazole Yes Yes Yes No No No No No No Bolus 200 days X
Panacur 10% Oral Suspension MSD AH Fenbendazole Yes Yes Yes No No No No No No Oral Drench/In-Feed 12 days 5 days
Panacur 4% Powder MSD AH Fenbendazole Yes Yes Yes No No No No No No In-Feed/pre-mix 14 days 5 days
Tramazole 2.5% SC Tulivin Labs Albendazole Yes Yes Yes Yes (adult only) No No No No No Oral Drench Co, Se 14 days 60 hrs
Zerofen 2.5% Chanelle AH Fenbendazole Yes Yes No No No No No No No Oral Drench 14 days 132 hrs
Zerofen 10% Chanelle AH Fenbendazole Yes Yes No No No No No No No Oral Drench 14 days 132 hrs

1-BZ 2-LV Group 2: Levamisole (LV) (Yellow)

3-ML 4-AD 5-SI

COMPANY CHEMICAL PARASITES CONTROLLED TRACE WITHDRAWAL Milk

PRODUCT USE
NAME NAME Roundworm Lungworm Tapeworm Fluke Mites Warbles Lice Hornflies Eyeworm ELEMENTS PERIOD (MEAT) withhold

Chanaverm 7.5% Chanelle AH Levamisole Yes Yes No No No No No No No Oral Drench 20 days X

Levacide 7.5% Norbrook
Levamisole Yes Yes No No No No No No No Injection S/C 28 days X
Solution for Injection Labs
Norbrook
Levacide Low Volume 7.5% Levamisole Yes Yes No No No No No No No Oral Drench 14 days X
Labs
Norbrook
Levacide Pour-On Levamisole Yes Yes No No No No No No No Pour-On 28 days X
Labs
Levamisole Injection Downland Levamisole Yes Yes No No No No No No No Injection S/C 28 days X
Levacur SC 3% MSD AH Levamisole Yes Yes No No No No No No No Oral Drench 20 days X

Check product labels for full and final details X = not for use in cattle producing milk for human consumption
 Cattle Endoparasiticides and Ectoparasiticides

Z 2-LV 3-ML Group 3: Macrocyclic Lactones (ML) (Clear)

4-AD 5-SI

COMPANY CHEMICAL PARASITES CONTROLLED WITHDRAWAL Milk

PRODUCT USE
NAME NAME Roundworm Lungworm Tapeworm Liver fluke Mites Warbles Lice Hornflies Eyeworm PERIOD (MEAT) withhold

Animec 1% Injection Chanelle AH Ivermectin Yes Yes No No Yes Yes Yes No No Injection S/C 49 days X

Animec Pour-On 0.5% Chanelle AH Ivermectin Yes Yes No No Yes Yes Yes No No Pour-On 28 days X
Bimectin Injection Bimeda Ivermectin Yes Yes No No Yes Yes Yes No No InjectionS/C 49 days X
Bimectin Pour-On for Cattle Bimeda Ivermectin Yes Yes No No Yes Yes Yes Yes No Pour-On 31 days X
Cydectin 0.5% Pour-On for Cattle Zoetis Moxidectin Yes Yes No No Yes Yes Yes Yes No Pour-On 14 days 6 days
Cydectin 1% Injectable Solution Zoetis Moxidectin Yes Yes No No Yes Yes Yes No No Injection S/C 65 days 60* days
for Cattle
Cydectin 10% LA for Cattle Zoetis Moxidectin Yes Yes No No Yes Yes Yes No No Ear Injection 108 days 80* days
Dectomax 10mg/ml Solution for Elanco AH Doramectin Yes Yes No No Yes Yes Yes No No Injection S/C 70 days 60* days
Injection for Cattle and Sheep
Dectomax Pour-On Elanco AH Doramectin Yes Yes No No Yes Yes Yes Yes No Pour-On 35 days 60* days
Depidex Pour-On Elanco AH Ivermectin Yes Yes No No Yes Yes Yes No No Pour-On 28 days 60* days
Ecomectin 10mg/ml Eco AH Ivermectin Yes Yes No No Yes Yes Yes No No Injection S/C 49 days 60* days
Solution for Injection
Ecomectin 5mg/ml Pour-on Eco AH Ivermectin Yes Yes No No Yes Yes Yes No No Pour-On 31 days 60* days
Solution for Cattle
Eprecis 20mg/ml solution for Ceva AH Eprinomectin Yes Yes No No Yes Yes Yes Yes No Injection SC 63 days Zero
injection for cattle
Eprecis 5mg/ml pour-on solution Ceva AH Eprinomectin Yes Yes No No Yes Yes Yes Yes No Injection SC 15 days Zero
for cattle
Eprinex Pour-On Merial AH Eprinomectin Yes Yes No No Yes Yes Yes No No Pour-On 15 days Zero
Eprizero Pour-On Norbrook Labs Eprinomectin Yes Yes No No Yes Yes Yes No No Pour-On 10 days Zero
Ivomec Classic Ivermectin
Merial AH Yes Yes No No Yes Yes Yes No No Injection S/C 49 days 60* days
Injection for Cattle and Sheep
Ivomec Classic Ivermectin
Merial AH Yes Yes No No Yes Yes Yes No No Pour-On 15 days 60* days
Pour-On for Cattle
Neoprinil 5mg/ml Pour-On solution Ivermectin
Virbac Yes Yes No No Yes Yes Yes No No Pour-On 15 days Zero
for cattle
Noromectin Multi Injection Norbrook Labs Ivermectin Yes Yes No No Yes Yes Yes No No Injection S/C 49 days 60* days
Noromectin Pour-On Norbrook Labs Ivermectin Yes Yes No No Yes Yes Yes No No Pour-On 28 days 60* days
Panomec Injection for Cattle, Sheep Ivermectin Injection S/C 49 days
Merial AH Yes Yes No No Yes Yes Yes No No 60* days
and Pigs
Paramectin Multi Injection Norbrook Labs Ivermectin Yes Yes No No Yes Yes Yes No No Injection S/C 49 days 60* days
Paramectin Pour-On Norbrook Labs Ivermectin Yes Yes No No Yes Yes Yes No No Pour-On 28 days 60* days
Premadex 1% Solution for Injection Downland Ivermectin Yes Yes No No Yes Yes Yes No Yes Injection S/C 35 days 60* days
Premadex Pour-On Downland Ivermectin Yes Yes No No Yes Yes Yes No No Pour-On 28 days 60* days
 COMPANY CHEMICAL PARASITES CONTROLLED WITHDRAWAL Milk
PRODUCT USE
NAME NAME Roundworm Lungworm Tapeworm Liver fluke Mites Warbles Lice Hornflies Eyeworm PERIOD (MEAT) withhold

Qualimec 10mg/ ml Solution Ivermectin

Elanco AH Yes Yes No No Yes Yes Yes No No Injection S/C 49 days 60* days
for Injection
Qualimec 5mg/ ml Ivermectin
Elanco AH Yes Yes No No Yes Yes Yes No No Pour-On 31 days 60* days
Pour-On Solution
Virbamec Injectable Solution Virbac Ivermectin Yes Yes No No Yes Yes Yes No Yes Injection S/C 49 days 60* days
Virbamec Pour-On Virbac Ivermectin Yes Yes No No Yes Yes Yes No No Pour-On 28 days 60* days
Zermex Pour-On Downland Ivermectin Yes Yes No No Yes Yes Yes Yes No Pour-On 14 days 6 days
Zermex 10% LA for Cattle Downland Ivermectin Yes Yes No No Yes Yes Yes No No Ear Injection 108 days 80* days

Combination Products
COMPANY CHEMICAL PARASITES CONTROLLED WITHDRAWAL Milk
PRODUCT USE
NAME NAME Roundworm Lungworm Tapeworm Liver fluke Mites Warbles Lice Hornflies Eyeworm PERIOD (MEAT) withhold

Animec Super Chanelle AH Ivermectin

Yes Yes No Yes (adult only) Yes Yes Yes No No Injection S/C 66 days 60* days
Injection for Cattle Clorsulon
Ivermectin
Bimectin Plus Bimeda Yes Yes No Yes (adult only) Yes Yes Yes No No Injection S/C 66 days 60* days
Clorsulon
Norbrook Ivermectin
Closamectin Injection Yes Yes No Yes (adult only) Yes Yes Yes No No Injection S/C 49 days X
Labs Closantel
Norbrook Ivermectin
Closamectin Pour-On Yes Yes No Yes (adult only) Yes Yes Yes No No Pour-On 28 days X
Labs Closantel
Levamisole
Combinex Cattle Elanco AH Yes Yes No Yes - all stages No No No No No Oral Drench 56 days X
Triclabendazole
Cydectin Yes - immature
Cydectin TriclaMox Zoetis Yes Yes No No No No No No Pour-On 143 days X
Triclabendazole and adult
Downland Levamisole
Downland Yes Yes No Yes (adult only) No No No No No Oral Drench 5 days X
Fluke & Worm Oxyclozanide
Ivomec Super Ivermectin
Merial AH Yes Yes No Yes (adult only) Yes Yes Yes No No Injection S/C 66 days 60* days
Injection for Cattle Clorsulon
Levamisole
Levafas Diamond Norbrook Labs Yes Yes No Yes (adult only) No No No No No Oral Drench 5 days X
Oxyclozanide
Ivermectin
Norofas Downland Yes Yes No Yes (adult only Yes No Yes No No Pour-On 28 days X
Closantel
Ivermectin
Supremadex Downland Yes Yes No Yes (adult only) Yes Yes Yes No No Injection S/C 66 days 60* days
Clorsulon
Ivermectin
Virbamec Super Virbac Yes Yes No Yes (adult only) Yes Yes Yes No No Injection S/C 66 days 60* days
Clorsulon
*Not permitted for use in cattle producing milk for human consumption or industrial purposes, or in dry cows and Check the datasheets of individual products for mite
pregnant heifers within stated days before calving (check specific details).
Check product labels for full and final details species activity as it does vary.
X = not for use in cattle producing milk for human consumption.
Flukicides
COMPANY PARASITES CONTROLLED WITHDRAWAL Milk
PRODUCT CHEMICAL NAME USE
NAME Roundworm Lungworm Tapeworm Liver fluke Mites Warbles Lice Hornflies Eyeworm PERIOD (MEAT) withhold

Endofluke 10% Bimeda Triclabendazole No No No Yes - all stages No No No No No Oral Drench 56 days 47* days
Fasinex 240 Elanco AH Triclabendazole No No No Yes - all stages No No No No No Oral Drench 52 days 50* days
Tribex 10 Chanelle AH Triclabendazole No No No Yes - all stages No No No No No Oral Drench 56 days X
Yes - all stages
Triclacert 10% Downland Triclabendazole No No No No No No No No Oral Drench 56 days X
fluke
Yes - immature
Trodax 34% Merial AH Nitroxynil No No No No No No No No Injection S/C 60 days X
and adult
Yes
Zanil MSD AH Oxyclozanide No No No No No No No No Oral Drench 28 days 72 hrs
(adult only)

Ectoparasiticides – Synthetic Pyrethroids

COMPANY PARASITES CONTROLLED WITHDRAWAL Milk
PRODUCT CHEMICAL NAME USE
NAME Roundworm Lungworm Tapeworm Liver fluke Mites Warbles Lice Flies Hornflies Eyeworm PERIOD (MEAT) withhold

Butox Swish MSD AH Deltamethrin No No No No No No Yes Yes No No Pour-On 20 days Zero

Deltanil Virbac Deltamethrin No No No No No No Yes Yes No No Pour-On 17 days Zero
Dysect Cattle Pour-On Zoetis Alphacypermethrin No No No No No No Yes Yes No No Pour-On 28 days Zero
Flectron Fly Tags Zoetis Cypermethrin No No No No No No No Yes No No Ear Tag Nil Zero
Flypor Elanco AH Permethrin No No No No Yes No Yes Yes No No Pour-On 3 days 6 hrs
Fly and Lice Spot On Insecticide Zoetis Deltamethrin No No No No No No Yes Yes No No Spot On 17 days Zero
Spotinor 10mg/ml Norbrook Deltamethrin No No No No No No Yes Yes No No Pour-On 17 days Zero
Zermasect Cattle Downland Alphacypermethrin No No No No No No Yes Yes No No Pour-On 28 days Zero

Ectoparasiticides – Miscellaneous
PARASITES CONTROLLED WITHDRAWAL
PRODUCT COMPANY NAME CHEMICAL NAME USE
Roundworm Lungworm Tapeworm Fluke Mites Warbles Lice Flies Hornflies Eyeworm PERIOD (MEAT)

Diethyltoluamide
Horse & cattle fly repellent – Battle Hayward and
p-Menthane-3, No No No No No No No Yes No No Topical Lotion Nil
Liquid Bower
8-diol

*Not permitted for use in cattle producing milk for human consumption or industrial purposes, or in dry cows and Check the datasheets of individual products for mite
pregnant heifers within stated days before calving (check specific details).
Check product labels for full and final details
species activity as it does vary.
X = not for use in cattle producing milk for human consumption.
Cattle treatment best practice

Dosing cattle correctly Injectables Boluses Oral drenches

Whichever method of administration is selected Injectables should be given according to the These types of wormers are administered Oral drenching guns are designed to deliver
it is important to read the manufacturer’s manufacturer’s instructions at the orally using product-specific equipment. the treatment towards the back of the
instructions carefully. Particular attention recommended injection site. Follow the manufacturers’ instructions closely mouth over the tongue, so the entire dose is
should be paid to: • Always use a clean, sterile syringe and needle. to ensure that the boluses are delivered swallowed at once to optimise efficacy.
• Class of stock for which the drug is If using a multiple injection gun, ensure the over the back of the tongue, so they can be • Make sure animals are properly restrained,
recommended and any limitations needle is disinfected between injections, for swallowed. Avoid any excess force, as this with their head held up
regarding use example with an automatic sterilization can cause damage to the throat and do not • Slide the nozzle of the dosing gun in the side
• Dose rate and any recommended increases system depress the plunger until you are satisfied with of the mouth and over the tongue so that
to deal with different parasite species or • If the site to be injected is dirty, clean the the positioning of the bolus. the entire dose is swallowed immediately
developmental stages skin and swab with an alcohol impregnated • Drenching equipment must be correctly
• Meat withholding period before slaughter wipe or cotton wool calibrated and in good working order
• Body weight assessment to avoid underdosing • Before injecting, check the expiry date and • Calibrate the gun using the product just
read the directions of the product to be before treatment starts by delivering two or
• Correct storage of wormers, ie away from
used. Some products need to be shaken more doses into a graduated measuring
direct sunlight, avoiding extremes of
before use cylinder
temperature. Check the use-by date and
once open, use within the time shown on • Use the correct sized needle according to Faulty equipment, or attempting to dose too
the packaging. Some products need to be the size of the animal and site of injection quickly, may mean that the barrel of the gun
well shaken before use • Ensure the animal is adequately restrained does not fill properly or that the liquid is full of
• Ensure that the equipment is appropriate for before attempting the bubbles
the product and is calibrated to deliver the injection
dose accurately. After use, rinse, clean and • For subcutaneous Storage
then dry the equipment before storage injections, raise
Wormers should be stored securely, away from
a fold of skin at
direct sunlight at 4-25oC. Check the ‘use-
Pour-Ons the injection site It is important that the animal stays as calm
by’ date and once open, use within the time
(mainly neck but some as possible and can swallow. This is normally
These should be applied along the length of shown on the packaging. Shake white (BZ)
are ear) recommended achieved by keeping the head and neck in a
the flattest part of the animal’s back, from the products well before use.
by the product manufacturer and inject straight line; it is very difficult to successfully
withers to the tail head.
carefully into the space created and safely complete administration if the neck
In general, animals should not be treated when is twisted and the animal is fighting you.
• If a large dose is to be delivered it may be
the hair is wet or if rain is anticipated within
advisable to split the dose between two
two hours of treatment. However, some
injection sites. After the injection, briefly
products are waterproof and can be used on
massage the site to improve the dispersal of
wet animals. Areas of damaged skin should be
the injected material
avoided, as should areas contaminated with
mud or manure. • Dispose of the needle and syringe in
appropriate clinical waste and sharps
containers
What type of anthelmintic should be used?
Parasite Treatment advice Product notes
Gutworms Worming is essential to break the lifecycle of gutworms where cattle are grazing Macrocyclic lactone (ML) products are active against inhibited larvae. Benzimidazoles may also
eg infected pastures. Treatments should aim to limit disease and minimise pasture be used, but their efficacy against inhibited larvae can be unpredictable.
contamination. At housing of first (and probably second) year grazing animals, it Levamisole is ineffective against larval O. ostertagi.
Ostertagia is important to choose cattle anthelmintics (commonly known as wormers) that
Cooperia are effective against inhibited fourth stage Ostertagia ostertagi larvae which can
cause Type II ostertagiasis (resulting from the emergence of thousands of inhibited
larvae from the wall of the fourth stomach) – a serious, potentially fatal disease
known as winter scour.
Lungworm Lungworm infection (husk) usually occurs in youngstock during the second If considering using a lungworm vaccine, take veterinary advice to ensure correct use.
half of the grazing season. Without good lungworm control cattle maybe more Care is required to avoid using wormers for a number of weeks before and after vaccine
susceptible to pneumonia after housing. As well as being controlled by most administration.
anthelmintics, lungworm in cattle can be effectively controlled using an oral
lungworm vaccine.
Liver fluke Treatment for fluke should take account of the particular risk, time of year and the Different products will kill different ages of fluke so product selection is important. There have
stage of development of the fluke. This should be discussed with your adviser. been reports of triclabendazole resistance so where appropriate other products should be used.
If rumen fluke are suspected discuss options with your vet, as treatment is not
always required, few products are effective and the dose rate may need to be
adjusted.
Ectoparasites Spread of lice and mange is by close contact and occurs most frequently during Ectoparasites can be controlled with synthetic pyrethroid products or MLs (avermectins and
eg lice, the winter months when cattle are housed. milbemycins). The range of ectoparasites controlled differs amongst formulations so it is
mange, ticks, Low levels of ectoparasite infection can be tolerated. Where heavy infestations important to read the label for each product before use and get appropriate advice.
flies occur all in-contact cattle should be treated.

Products that combine a wormer and flukicide can seem like an attractive option for broad spectrum control with a single administration and it is recommended that they are used if:
• Cattle require treatment for both worms and fluke
• The wormer is effective against the stages of the target worms present and the value of any persistent activity is assessed
• The flukicide has the appropriate activity for the stages of liver fluke likely to be present

Consult your vet, Suitably Qualified Person (SQP) for more detailed advice to ensure you choose the right product and administer it in the right way.
 Treatments for sheep parasite control – Sheep Endoparasiticides

1-BZ Group 1: Benzimidazoles (BZ) (White)

2-LV 3-ML 4-AD 5-SI

COMPANY PARASITES CONTROLLED TRACE WITHDRAWAL

PRODUCT CHEMICAL NAME USE
NAME Roundworm Lungworm Tapeworm Liver fluke Mange mites Nasal bots Sheep scab ELEMENTS PERIOD (MEAT)

Albacert Downland Albendazole Yes Yes Yes Yes (adult only) No No No Oral Co, Se 5 days
Albenil SC Virbac Albendazole Yes Yes Yes Yes (adult only) No No No Oral Co, Se 5 days
Albex 2.5% SC Chanelle AH Albendazole Yes Yes Yes Yes (adult only) No No No Oral Co, Se 5 days
Albex 10% Chanelle AH Albendazole Yes Yes Yes Yes (adult only) No No No Oral Co, Se 5 days
Allverm 4% Elanco AH Ricobendazole Yes Yes Yes Yes (adult only) No No No Oral Co, Se 3 days
Benzimole Mole Valley Albendazole Yes Yes Yes Yes (adult only) No No No Oral 5 days
Bovex 2.265% Chanelle AH Oxfendazole Yes Yes Yes No No No No Oral 24 days
Endospec SC 2.5% Bimeda Albendazole Yes Yes Yes Yes (adult only) No No No Oral Co, Se 4 days
Endospec SC 10% Bimeda Albendazole Yes Yes Yes Yes (adult only) No No No Oral Co, Se 4 days
Ovidown SC Downland Oxfendazole Yes Yes Yes No No No No Oral Co, Se 21 days
Panacur 10% Oral Suspension MSD AH Fenbendazole Yes Yes Yes No No No No Oral 15 days
Parafend 2.265% Norbrook Labs Oxfendazole Yes Yes Yes No No No No Oral 10 days
Rycoben SC 2.5% Oral Suspension Elanco AH Ricobendazole Yes Yes Yes Yes (adult only) No No No Oral Co, Se 3 days
Tramazole 2.5% SC Tulivin Labs Albendazole Yes Yes Yes Yes (adult only) No No No Oral Co, Se 4 days
Zerofen 2.5% Chanelle AH Fenbendazole Yes Yes Yes No No No No Oral 21 days
Zerofen 10% Chanelle AH Fenbendazole Yes Yes Yes No No No No Oral 21 days

1-BZ 2-LV
Group 2: Levamisole (LV) (Yellow)
3-ML 4-AD 5-SI

COMPANY PARASITES CONTROLLED TRACE WITHDRAWAL

PRODUCT CHEMICAL NAME USE
NAME Roundworm Lungworm Tapeworm Liver fluke Mange mites Nasal bots Sheep scab ELEMENTS PERIOD (MEAT)

Chanaverm Chanelle AH Levamisole Yes Yes No No No No No Oral 20 days

Levacide 7.5% Injection
Norbrook Labs Levamisole Yes Yes No No No No No 15 days
solution for injection S/C
Levacide Low Volume Norbrook Labs Levamisole Yes Yes No No No No No Oral 21 days

Levacur SC 3% MSD AH Levamisole Yes Yes No No No No No Oral Co, Se 20 days

Levamisole Injection Downland Levamisole Yes Yes No No No No No Injection S/C 15 days

Levamole Mole Valley Levamisole Yes Yes No No No No No Oral 20 days
 Treatments for sheep parasite control – Sheep Endoparasiticides

Z 2-LV 3-ML
Group 3: Macrocyclic Lactones (ML) (Clear)
4-AD 5-SI

COMPANY PARASITES CONTROLLED WITHDRAWAL

PRODUCT CHEMICAL NAME USE
NAME Roundworm Lungworm Tapeworm Liver fluke Mange mites Nasal bots Sheep scab PERIOD (MEAT)

Animec Oral for Sheep Chanelle AH Ivermectin Yes Yes No No No Yes No Oral Drench 10 days

Bimectin Bimeda Ivermectin Yes Yes No No No Yes No Injection S/C 42 days

Cydectin 0.1% Oral Zoetis Moxidectin Yes Yes No No No No No Oral Drench 14 days

Cydectin1% injection Zoetis Moxidectin Yes Yes No No No Yes Yes Injection S/C 70 days
Cydectin 20mg/ml LA injection Zoetis Moxidectin Yes Yes No No No Yes Yes Injection S/C 104 days
Dectomax 10mg/ml
Elanco AH Doramectin Yes Yes No No No Yes Yes Injection I/M 70 days
Solution for Injection
Depidex Elanco AH Ivermectin Yes Yes No No No Yes No Oral Drench 14 days
Ecomectin 10mg/ml Solution for
Eco AH Ivermectin Yes Yes No No Yes Yes Yes Injection S/C 42 days
Injection
Ivomec Classic Injection Merial AH Ivermectin Yes Yes No No No Yes Yes Injection S/C 37 days
Molemec Drench Mole Valley Ivermectin Yes Yes No No No Yes No Oral 6 days
Molemec Injection Mole Valley Ivermectin Yes Yes No No No Yes Yes Injection S/C 37 days
Noromectin Drench Norbrook Labs Ivermectin Yes Yes No No No Yes No Oral Drench 14 days
Noromectin Multi Injection Norbrook Labs Ivermectin Yes Yes No No No Yes Yes Injection S/C 42 days
Oramec Merial AH Ivermectin Yes Yes No No No Yes No Oral Drench 6 days
Panomec Injection for Cattle,
Merial AH Ivermectin Yes Yes No No No Yes Yes Injection S/C 37 days
Sheep and Pigs
Paramectin Multi Injection  orbrook Labs
N Ivermectin Yes Yes No No No Yes Yes Injection S/C 42 days
ParamectinDrench Norbrook Labs Ivermectin Yes Yes No No No Yes No Oral Drench 14 days
Premadex 1% Injection Downland Ivermectin Yes Yes No No Yes Yes Yes Injection S/C 42 days
Qualimec Injection 10mg/ml
Elanco AH Ivermectin Yes Yes No No No Yes Yes Injection S/C 42 days
Solution for Injection
Vectin 0.08% MSD AH Ivermectin Yes Yes No No No Yes No Oral Drench 14 days
Zermex Drench Downland Moxidectin Yes Yes No No No No No Oral Drench 14 days
Zermex 1% Injection Downland Moxidectin Yes Yes No No No Yes Yes Injection S/C 70 days
Zermex 20mg/ml LA for injection Downland Moxidectin Yes Yes No No No Yes Yes Injection S/C 104 days
I/M = intramuscular S/C = subcutaneous

Check product labels for full and final details

 Treatments for sheep parasite control – Sheep Ectoparasiticides

V 3-ML 4-AD
Group 4: Amino Acetonitrile Derivatives (AD) (Orange)
5-SI

COMPANY PARASITES CONTROLLED WITHDRAWAL

PRODUCT CHEMICAL NAME USE
NAME Roundworm Lungworm Tapeworm Liver fluke Mange mites Nasal bots Sheep scab PERIOD (MEAT)

Zolvix Elanco AH Monepantel Yes No No No No No No Oral 7 days

ML 4-AD 5-SI
Group 5: Spiro-indoles (SI) available as a Multi-active (Purple)
COMPANY PARASITES CONTROLLED WITHDRAWAL
PRODUCT CHEMICAL NAME USE
NAME Roundworm Lungworm Tapeworm Liver fluke Mange mites Nasal bots Sheep scab PERIOD (MEAT)

Startect Dual Active Zoetis Derquantel Abamectin Yes Yes No No No No No Oral 14 days

Combination Products
COMPANY PARASITES CONTROLLED WITHDRAWAL
PRODUCT CHEMICAL NAME USE
NAME Roundworm Lungworm Tapeworm Liver fluke Mange mites Nasal bots Sheep scab PERIOD (MEAT)

Yes - including 7
Closamectin Injection Norbrook Labs Ivermectin Closantel Yes Yes No No Yes No Injection S/C 28 days
weeks immature
Yes - including 7
Closiver Solution for Injection Downland Ivermectin Closantel Yes Yes No No Yes No Injection S/C 28 days
weeks immature
Yes - including
Levamisole
Combinex Sheep Elanco AH Yes Yes No immature fluke from No No No Oral 56 days
Triclabendazole
2 days of age

Moxidectin Yes - including early

Cydectin TriclaMox Zoetis Yes Yes No No No No Oral 31 days
Triclabendazole immature fluke

Levamisole
Downland Fluke & Worm Downland Yes Yes No Yes (adults only) No No No Oral 28 days
Oxyclozanide
Yes - including
Ivermectin
Fasimec Duo Elanco AH Yes Yes No immature fluke from No Yes No Oral 27 days
Triclabendazole
under 1 week of age
Levamisole
Levafas Diamond Norbrook Labs Yes Yes No Yes (adults only) No No No Oral 5 days
Oxyclozanide
Levitape Elanco AH Levamisole Praziquantel Yes Yes Yes No No No No Oral 28 days
Yes - including
Mebadown Super Oral Suspension Downland Mebendazole Closantel Yes Yes Yes immature fluke over No No No Oral 65 days
5 weeks of age
Yes (including
Supaverm Oral Suspension Elanco AH Mebendazole Closantel Yes Yes Yes immature fluke over No No No Oral 65 days
5 weeks of age)
I/M = intramuscular S/C = subcutaneous NB Lice – endectocides do not cover biting (chewing) lice which are the species of importance in the UK
Flukicides
COMPANY PARASITES CONTROLLED WITHDRAWAL
PRODUCT CHEMICAL NAME USE
NAME Roundworm Lungworm Tapeworm Liver fluke Mange mites Nasal bots Sheep scab PERIOD (MEAT)

Endofluke 10% Bimeda Triclabendazole No No No Yes - including immature fluke from 2 days of age No No No Oral 56 days
Fasinex 5% Elanco AH Triclabendazole No No No Yes - including immature fluke from 2 days of age No No No Oral 56 days
Fasinex 100 Elanco AH Triclabendazole No No No Yes - including immature fluke from 2 days of age No No No Oral 35 days
Flukiver 5% w/v oral suspension Yes - including immature fluke over 5 weeks of age
Elanco AH Closantel No No No No Yes No Oral 42 days
Haemonchus Contortus*
Tribex 5% Chanelle AH Triclabendazole No No No Yes - including immature fluke from 2 days of age No No No Oral 56 days
Triclacert 5% Downland Triclabendazole No No No Yes - including immature fluke No No No Oral 56 days
Triclafas Drench Norbrook Labs Triclabendazole No No No Yes - including immature fluke from 2 days of age No No No Oral 56 days
Trodax 34% Yes - including immature fluke
Merial AH Nitroxynil No No No No No No Injection S/C 49 days
Haemonchus Contortus•
Zanil MSD AH Oxyclozanide No No No Yes (adult only) No No No Oral 28 days
* Barbers Pole Worm

Injectables for Sheep Scab

COMPANY WITHDRAWAL MOVE TO CLEAN
PRODUCT CHEMICAL NAME SHEEP SCAB NASAL BOTS
NAME PERIOD (MEAT) PASTURE

Cydectin 1% Zoetis Moxidectin 28 days persistent activity for protection. Two injections 10 days apart to treat existing scab 3 70 days No

Cydectin 20mg/ml LA injection Zoetis Moxidectin 60 days persistent activity for protection. One injection to treat existing scab 3 104 days No

Dectomax 10mg/ml Solution for Injection for Cattle and Sheep Elanco AH Doramectin One injection 3 70 days Yes

Ecomectin 10mg/ml Solution for Injection Eco AH Ivermectin Two injections 7 days apart 3 42 days Yes

Ivomec Classic Merial AH Ivermectin Two injections 7 days apart 3 37 days Yes

Molemec Injection Mole Valley Ivermectin Two injections 7 days apart 3 37 days Yes

Noromectin Multi Injection Norbrook Labs Ivermectin Two injections 7 days apart 3 42 days Yes

Panomec Injection for Cattle, Sheep and Pigs Merial AH Ivermectin Two injections 7 days apart 3 37 days Yes

Paramectin Multi Injection Norbrook Labs Ivermectin Two injections 7 days apart 3 42 days Yes

Premadex 1% Injection Downland Ivermectin Two injections 7 days apart 3 42 days Yes

Qualimec Injection 10mg/ml Solution for Injection Elanco AH Ivermectin Two injections 7 days apart 3 42 days Yes

Zermex 1% Injection Downland Moxidectin 28 days persistent activity for protection. Two injections 10 days apart 3 70 days No

Zermex 20mg/ml LA for injection Downland Moxidectin 60 days persistent activity for protection. One injection to treat 3 104 days No

Check product labels for full and final details

Plunge Dips
PRODUCT COMPANY NAME CHEMICAL NAME BLOWFLY SHEEP SCAB LICE TICKS WITHDRAWAL PERIOD (MEAT)

Osmonds Gold Fleece Dip Bimeda Diazinon 8 weeks protection Up to 4 weeks protection 3 3–6 weeks protection 49 days

Paracide 62 Animax Ltd Diazinon 8 weeks protection Up to 4 weeks protection 3 3–6 weeks protection 70 days

Pour-Ons
PRODUCT COMPANY NAME CHEMICAL NAME BLOWFLY LICE TICKS WITHDRAWAL PERIOD (MEAT)

CLiK Elanco AH Dicyclanil (IGR) 16 weeks P No No 40 days

CLiKZiN Elanco AH Dicyclanil (IGR) 8 weeks P No No 7 days

Crovect Elanco AH Cypermethrin 6–8 weeks P+T Kills existing lice Up to 10 weeks 8 days

Ectofly 12.5mg/ml Bimeda Cypermethrin 6-8 weeks P+T Kills existing lice No 8 days

Deltanil Virbac Deltamethrin Treats established strike only 4-6 week reduction in incidence 6 weeks 35 days

Dysect Zoetis Alpha-cypermethrin 8–10 weeks P+T Kills existing lice 8–12 weeks 49 days

Fly & Lice Spot On Zoetis Deltamethrin Treats established strike only 4–6 week reduction in incidence Up to 6 weeks 35 days

Spotinor 10mg/ml Norbrook Deltamethrin Treats established strike only 4-6 weeks reduction in incidence 6 weeks 35 days

Vectocert 1.25% Downland Cypermethrin 6-8 weeks P+T Kills existing lice No 8 days

Vetrazin Elanco AH Cyromazine (IGR) 10 weeks No No 28 days

Zermasect Sheep Downland Alpha-cypermethrin 8–10 weeks P+T Kills existing lice 8–12 weeks 49 days

P = Prevention, T = Treatment

Check product labels for full and final details

Sheep treatment best practice

Subcutaneous injections Intramuscular injections Pour-ons and spot-ons

Subcutaneous injections need to be administered with care to Intramuscular injections are made into muscle. Again, care is Pour-ons and spot-ons need
ensure the product is placed under the skin and not into fleece needed to ensure that the product is deposited in muscle and to be applied accurately and
or muscle. The sheep needs to be well restrained and the skin not just under the skin. This requires sheep to be well restrained. each manufacturer may
‘tented’ away from the underlying muscle. The preferred The correct site is on the side of the neck 10-15cm recommend subtle differences.
injection site is 10-15cm (4-6 inches) below the ear on the side of (4-6 inches) in front of the shoulder in the mid neck area well Use appropriate and calibrated
the neck (see diagram). Usually a 1.6cm (5/8th inch) needle is above the large jugular vein. Insert a 2.5-4cm (1-1½ inch) guns, always clean with warm
ideal. After administration the site should be gently massaged. needle at 60° to the neck aiming inwards and upwards towards soapy water and then rinse
the head. Again, massage in after administration. after use. Store in a safe dry
The neck site for intramuscular injections ensures that no valuable place. When treating sheep
cut of meat is damaged and the constant movement of the neck with these products, make
ensures good dispersion of the product. sure they are applied along the back line. If placed to one side,
the product will not spread evenly around the body. No pour-on
or spot-on is effective against sheep scab.

Skin
Subcutaneous Subcutaneous
tissue
Fat
Intramuscular
Muscle

Sheep product information compiled in association with

Sheep treatment best practice

Dosing Calibrate and maintain the drench gun Slot the nozzle in the gap between molar and incisor teeth and
Always check the gun is then over the back of the tongue. The nozzle must be placed over
Weigh – do not guess
delivering the right amount the back of the tongue. If the wormer is just put into the mouth,
Underestimating the weight it will bypass the rumen as it escapes down the oesophageal
before you drench. Remove
of sheep is a common cause groove and will be less effective. This is particularly important
the plunger from a 10ml
of underdosing. Select and for white (BZ) drenches.
syringe, put a thumb over
weigh the biggest sheep in
the end and squirt the dose
the group to determine the
into it, making sure there are Withholding food
correct dose. If there is a wide
no air bubbles left. Adjust the Research has shown that the efficacy of the white (BZ) and clear
range of weights, consider
gun until the dose delivered is (AV) drenches can be improved by withholding food for 12-24
splitting the group, then
correct. Drenching guns should hours before treatment. It is inadvisable to deprive heavily
weigh the heaviest in each
also be well maintained and pregnant ewes of food, so if you treat this class of stock with
section. Do not forget to
replaced regularly. Clean with anthelmintics, then you may wish to use yellow drenches (LV)
check that the weigh crate is
warm soapy water after use and check springs and tubes to as their efficacy is less dependent on rumen fill.
accurate before starting!
make sure there are no kinks that will form air bubbles.
Storage

Drench correctly Wormers should be stored securely, away from direct sunlight
at 4-25oC. Check the ‘use-by’ date and, once open, use within
The drenching technique is a vital part of ensuring that the the time shown on the packaging. Shake white (BZ) products
wormer does its job effectively. Make sure the sheep are well before use.
properly restrained and cannot leap around when they are
being drenched so they swallow the whole amount. Sheep can
also suffer serious injury, or even death, if they are unrestrained Dipping
and the gun penetrates the tissues at the back of the mouth. For plunge dipping it is essential to know the capacity of the
Place a hand under the head and tilt slightly to the side. bath. Only use the two closed systems to charge the bath and to
top up. Always top up as per instructions, if not, the dip wash will
strip out and later sheep will not carry enough ectoparasiticide
for it to be effective. Do not dip tired, thirsty or heat-stressed
sheep. Allow dipped sheep to drain in designated draining pens
and do not return to pasture until excess dip has been shed.
When dipping, use protective clothing, handle equipment
carefully and stick to manufacturer instructions.
Plunge dip products are not approved for use in shower or spray
races and may be less effective compared to plunge dipping
because the product may not reach all parts of the fleece in
sufficient concentrations.
Wormer Purchase Checklist

Do you need to treat? • Withdrawal periods For more information contact:

Which animals are at risk? Consider withdrawal periods carefully when choosing Better Returns Programme
a product. AHDB Beef & Lamb
Have animals been grazing high-risk pastures?
Stoneleigh Park
Have weather/grazing conditions increased the risks? (eg wet • Administer it effectively Kenilworth
conditions and liver fluke infection) Warwickshire
Make sure you have the right equipment, it is properly calibrated CV8 2TL
Has the risk been monitored, eg using Faecal Egg Counts (FECs)? and you know the correct dose rate for the weight of animal
Can management be used to reduce the risk and the need to to be treated. Avoid under- or over-dosing. Always follow the Tel: 024 7647 8834
treat? eg move lambs/calves to lower risk grazing manufacturers’ recommendations and store products Email: brp@ahdb.org.uk
correctly and do not use out-of-date product. beefandlamb.ahdb.org.uk
Product Choice
AHDB Beef & Lamb is a division of the Agriculture and Horticulture
• What pack size is required? Development Board (AHDB)
• What are the target parasites?
If a pack size is slightly less than required, leave one or two fit © Agriculture and Horticulture Development Board 2016
Treatments should be chosen according to the target All rights reserved.
animals not dosed; never underdose the whole group.
parasites, the life cycle stage, time of year and objective
(curative or preventative). Use combination products only While the Agriculture and Horticulture Development Board seeks to ensure
• Do not mix wormers with any other product prior that the information contained within this document is accurate at the time of
when the target parasites are present.
to administration printing, no warranty is given in respect thereof and, to the maximum extent
permitted by law the Agriculture and Horticulture Development Board accepts
• Avoid overuse of the same products no liability for loss, damage or injury howsoever caused (including that caused
by negligence) or suffered directly or indirectly in relation to information and
Consider alternative chemical groups where possible opinions contained in or omitted from this document.
to reduce selection for resistance to one group.
The text of this document (this excludes, where present, any logos) may
be reproduced free of charge in any format or medium providing that it is
reproduced accurately and not in a misleading context.
Consult your vet or advisor (SQP) for further advice when purchasing anthelmintics if you require clarification
The material must be acknowledged as Agriculture and Horticulture
Development Board copyright and the document title specified. Where third
party material has been identified, permission from the respective copyright
holder must be sought.
This publication is available from our website at beefandlamb.ahdb.org.uk.
Any enquiries related to this publication should be sent to us at AHDB Beef &
Lamb, Stoneleigh Park, Kenilworth, Warwickshire CV8 2TL.