Scribd
Upload
793 views3 pages

Pathophysiology

The document outlines the pathophysiology of acute gastroenteritis, including predisposing factors such as extreme ages or immunocompromised states. It details the process from ingestion of contaminated food or water, pathogen entry and disruption of the intestinal flora, stimulation of the intestinal lining and increased secretion of fluids leading to diarrhea, dehydration, and other symptoms.

Uploaded by

Kita kita
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
793 views3 pages

Pathophysiology

The document outlines the pathophysiology of acute gastroenteritis, including predisposing factors such as extreme ages or immunocompromised states. It details the process from ingestion of contaminated food or water, pathogen entry and disruption of the intestinal flora, stimulation of the intestinal lining and increased secretion of fluids leading to diarrhea, dehydration, and other symptoms.

Uploaded by

Kita kita
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
You are on page 1/ 3

PATHOPHYSIOLOGY

ACUTE GASTROENTERITIS
PREDISPOSING FACTORS PRECIPITATING FACTORS
 Extreme ages  Poor sanitation
 Immuno-compromised Etiology: bacterial/viral  Contaminated food
 Immune deficiency and water
disease  Poor food preparation

Ingestion of contaminated
food/water

Pathogen enters
Gastrointestinal tract

Interrupted normal intestinal


flora activity

Pathogen release endotoxins

Stimulation of mucosal Invasion and destruction of mucosal


lining of intestine lining of intestine

Increased secretion of water and Irritation of intestinal mucosa


electrolytes into intestinal lumen

Increased secretion of chloride and bleeding ulceration Abdominal pain


bicarbonate ions

hematochezia
Inhibition of sodium reabsorption

Altered digestion and reabsorption


Increased secretion of protein-rich fluid Indigestion of food

Inhibition ofprotein-rich fluid Abdominal distension Excessive release of gas


reabsorption

Watery stool diarrhea Abdominal nausea Abdominal vomiting Excessive borborygmi


cramping pain

Los of fluids and electrolytes

dehydration
Increased secretion of protein-rich
fluid in bowel

You might also like