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ASE Presentation: DR - Ramesh Sharma Department of Obstetrics and Gynaecology. IOM, TU Teaching Hospital

This document presents the case of a 41-year-old female with a large abdominal mass. She had a history of total abdominal hysterectomy and possible bilateral salpingo-oophorectomy 6 years prior. Clinical examination revealed a large solid abdominal mass. Imaging studies including ultrasound, CT scan, and barium enema showed a large pelvic mass involving the ovaries along with metastatic deposits in the liver, lungs, and peritoneum. Tumor markers were elevated. The provisional diagnosis was an ovarian tumor with suspected metastasis. The patient was planned for staging laparotomy to further evaluate the extent of disease.

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0% found this document useful (0 votes)
91 views58 pages

ASE Presentation: DR - Ramesh Sharma Department of Obstetrics and Gynaecology. IOM, TU Teaching Hospital

This document presents the case of a 41-year-old female with a large abdominal mass. She had a history of total abdominal hysterectomy and possible bilateral salpingo-oophorectomy 6 years prior. Clinical examination revealed a large solid abdominal mass. Imaging studies including ultrasound, CT scan, and barium enema showed a large pelvic mass involving the ovaries along with metastatic deposits in the liver, lungs, and peritoneum. Tumor markers were elevated. The provisional diagnosis was an ovarian tumor with suspected metastasis. The patient was planned for staging laparotomy to further evaluate the extent of disease.

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We take content rights seriously. If you suspect this is your content, claim it here.
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CASE

PRESENTATION

Dr.Ramesh Sharma
Department of Obstetrics and Gynaecology.
IOM, TU Teaching Hospital.
HISTORY
 41 year Para 3 lady, from Rukum
 Post TAH with ? BSO done 6 years back at valley
Hospital
 Presented to our centre with complaint of
 Mass per abdomen – 1 year
 Abdominal pain and increase in size of mass for last 5
months
 Loss of appetite for 5 months
HISTORY …CONTD..
 Menstrual history- Post TAH
 Obstetric history- Para 3, all vaginal deliveries at
home
 Contraceptive history- none
HISTORY …CONTD..
Past history- TAH done 6 years back for fibroid
uterus
 The per operative finding revealed :
 A mass around 3 ×3 cm arising from the intestine which
was removed. Lumen not involved
 Uterus was enlarged, tubes and ovaries not commented
on
 Histopathology.
 Separate mass removed from the intestine shows
leiomyoma with hyaline degeneration
 Endometrium: proliferative; Cervix: chronic cervicitis
 Status of tubes and ovaries not mentioned
HISTORY …CONTD..
 Personal history- non smoker, doesn’t consume
alcohol
 Family history – no family h/o malignancy
CLINICAL EXAMINATION
 General condition- fair..thin built.
 Weight: 38 kg

 Vitals: stable

 Pallor, edema, dehydration, jaundice- nil

 No lymphadenopathy

 Breast, axilla : normal

 Chest- normal vesicular sounds all over

bilateral equal air entry


 CVS- S1 S2 M0
CLINICAL EXAMINATION..CONTD..
 Per abdomen-
 A huge mass(size 30 × 40 cm), solid, stony hard
in consistency, bosselated, irregular, well defined
margins in the upper and lateral parts, lower
border could not be felt, non tender, immobile
 No ascites
CLINICAL EXAMINATION..CONTD..
 Vulval inspection- no abnormality

 P/S- vault/vagina : normal

 P/V
 Vaginal vault appeared normal
 Firm mass felt in anterior fornix
 Upper pole could not be reached
CLINICAL EXAMINATION..CONTD..
 Per rectal examination:
 Rectal mucosa free
 Anteriorly, hard mass felt
PROVISIONAL DIAGNOSIS

 Ovarian tumor
INVESTIGATIONS
Hematology
Hb 10.8 gm%
Total Count 6110/ cu mm
Differential count N: 65 L:32 M:2 E:1
Platelets 3,48,000/cu mm
INVESTIGATIONS
Biochemistry
Na 146meq/l
K 4.5meq/l
RBS 4.1mmol/l
Urea 3.4mmol/l
Creatinine 73 µmol/l
Bilirubin T: 7µmol/l, D:1µmoml/l,
Protein 70 g/l
Albumin 36g/l
LDH 440U/l
SGOT 40U/l
SGPT 17U/l
ALP 215U/l
Coagulation Profile
BT 3 minutes
CT 5 minutes
PT 12 seconds (C:12 secs)
APTT 27 secs (C:27 secs)
Fibrinogen 330mg/dl (N: 200-400)
FDP D-dimers >200,<400 (N:<200)
INVESTIGATIONS
Serology
HBs Ag ELISA Non Reactive
HCV Ab ELISA Non Reactive
HIV 1-2 Ab ELISA Non Reactive

Tumor markers
CEA 6.2ng/ml (<4.7)
α- feto protein 10 ng/ml
CA-125 49 U/ml (<33.1)
β-HCG 55 mIU/ml (<7)

Urine RE/ME
Normal
IMAGING STUDIES
ULTRASONOGRAM OF ABDOMEN
 Findings:

 A large, solid mass seen in pelvis measuring


approximately 173 ×153 mm suggestive of ovarian
tumor.
 Upper abdomen: no abnormality detected
CT ABDOMEN AND PELVIS
CT SCAN REPORT : 2068/1/12

 Post hysterectomy status


 Huge (30x27x25cm)heterogeneously enhancing
mixed attenuation abdominopelvic mass with
ovaries not separately identified from this mass –
most likely malignant mass of ovarian origin ? side
of origin.
 Diffuse omental thickening and omental caking with
small round enhancing nodule (17.5x15.6mm)in
rectovesical pouch –s/o omental and peritoneal
metastatic deposits
 Poorly enhancing hypodense nodule(20.7x20.5mm)
in right lobe of liver –s/o metastatic lesion
CT SCAN REPORT : 2068/1/12

 Multiple mildly enhancing round and oval nodules


in scanned part of both lungs,largest 21.5x20.4mm
in size –s/o metastatic lesions.No pleural effusion
 Bilateral mild hydronephrosis most likely secondary
to ureteric compression by the above described
mass
 Mild ascites around lesion in pelvis

 No enlarged LN
BARIUM ENEMA
 (3/2/068) (Colonoscopy was tried but not able to go beyond
80 cm so, advised for barium enema )
 Soft tissue density (probably cystic) mass at
periumbilical region
 Fairly smooth outlined displacement of sigmoid
colon, ascending and transverse colon, more of sigmoid
with mildly dilated sigmoid loop
CHEST X-RAY
USG GUIDED FNAC

 (068/2/6) : mostly blood and few mesothelial cells


 Repeat USG guided FNAC sent on 068/2/9 : same
report
FINAL DIAGNOSIS
 ? Ovarian tumor with suspected metastasis to the
liver and lungs
MANAGEMENT

Planned for Staging Laparotomy on Friday


THANK YOU!!

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