Histology Final
1) If you want to investigate failed erythropoiesis you perform:
Bone marrow biopsy
2) The main functions of canaliculi is/are:
Transmits factors from osteocyte to osteoblasts in response to stress
3) The cell which is involved in ground substance production is:
All of the listed: (Both fibroblast and osteoblasts // Chondroblast //
Osteoblast)
4) Periosteum is connected to underlining bone via:
Sharpy's lines
5) The initial response to fracure repair is due to:
Ability of osteocytes to respond to tensile forces on the bone
6) Bony water is present within:
Perosteocytic space
7) Which of the following is not true regarding osteocytes:
Can undergo division
8) An osteoid is:
Osteocytes in lacuna within organic part of the bone matrix
9) What is the origin of osteoclasts:
Macrophage
10) Mark the Wrong contrast of the followings:
Osteocyte and osteoclasts
11) Bone callor formation occur during:
Endochondrial ossification
12) Where do you expect to find secondary bone in an adult:
All the listed except teeth sockets
13) In a developing bone, Bone callor is:
Initial bone tissue deposits within cartilgae
14) Osteoclasts are best active during:
Remodelling of bone
15) The premature bone cell that laydown bone tissue is:
Osteoblast
16) Regarding osteoclasts, Mark the Wrong statement:
Inhibited by parathyroid hormone
17) Regarding compact bone, MARK the WRONG statement:
Younger harvesian canal has smaller diameter than Old ones
18) In a longituidinal section of the outer plate of a long bone, you
expect to see:
Osteocytes arranged paralell to the long axis of the bone
19) In cartialge, nutrition pass by diffusion due to:
Rich in GAGS which absorb large amount of water
20) All types of cartilages share which of the followings:
Chonrdocytes within lacunae
21) Fetal skeleton is intially made mainly of:
Typical hyaline cartilage
22) The hyaline cartilage is present in the following ,EXCEPT:
Pinea of ear
23) If injury occurred to peripheral portion of knee menisci (cartilage
plate), what is the expected response?
Possible appostional growth and repair
24) All types of cartilages share the following features EXCEPT:
Perichondrium
25) Regarding fibrocartilage, Mark the Wrong statement:
Chonrdocytes are arranged in pairs within the matrix
26) The most common type of cartilage in our body is:
Hyaline cartilage
27) The main method by which mature cartilage regenerate is:
Apppositional growth
28) The oldest generation of chondrocyte are present at:
The center of a cartilage plate
29) What do cartilage and epithelial tissues have in common:
Both are avascular
30) What do glenoid labrum and intervertebral discs have in common:
Both made of fibrocartilge
31) The type of collagen fiber in fibrocatrilage and bone matrices is:
Collagen type 1
32) All of the following cartilages have perichondrium EXCEPT:
Articular cartilage
33) Stem cells of cartilage tissue is present at:
Perichondrium
34) Cartilage and bones share the following features EXCEPT:
Both undergo continous remodelling
35) Regarding epiphyseal growth plate, Which is true:
The second zone from above is zone of proliferation
36) Regarding fibrocartilage, Mark the Wrong statement:
Chonrdocytes are arranged in pairs within the matrix
37) Elastic and hyaline cartilages share the following features EXCEPT:
Fiber type present within extracellular matrix
38) The sense organ most closely associated with stretch reflexes (e.g.,
knee jerk) is the:
Muscle spindle
39) Neuromuscular junctions are located:
Midway along the length of the muscle fiber
40) Regarding the histology of CNS, Which is Wrong:
White matter is the inner layer in the spinal cord
41) Plasma membrane which surrounds the axon is called:
Axolemma
42) In the peripheral nervous system, the myelin sheat is formed by:
Fused plasma membranes of Schwan cells
43) Defective myelination results in a clinical disorder called:
Multiple sclerosis
44) The glial cell that forms perivascular feet is:
Astrocyte
45) The glial cell that acts as phagocyte in the CNS is:
Microglia
46) The glial cell that filters cerebrospinal fluid (CSF):
Ependymal cell
47) The ganglia: one of the followings is not correct:
Most of the sensory ganglia are formed of bipolar nerve cells
48) The nerve impulse is generated by the:
Initial axonal segment
49) The glia cell that does not developed from nervous origin:
Microgli
50) The parts of the neuron that has rough endoplasmic reticulum are:
a) Cell body
b) Axon
c) dendrites
d) All except axons
51) Special senses are conveyed by which neurons:
a) Multipolar neurons
b) Bipolar neurons
c) Unipolar
52) Dendrites contain the following EXCEPT:
a) Golgi apparatus
b) Mitochondria
c) neurofibrils
d) Nissl bodies (RER)
53) What is common features between smooth muscle and red type of
skeletal muscle?
a) Similar contractile property
b) striated in appearance
c) sustained production of force
54) What maintain the length of sacromeres?
2 of the listed
a) Cap-Z and tropomodulin ☺
b) Nebulin ☺
55) Microtubule act as a structural functional element in:
a) Neurons
b) Skeletal muscle cells
c) Smooth muscles cells
56) The type of conduction in unmyelinated nerve is:
a) Continuos type
b) Saltatory conduction
57) The reasons why we get shorter as we age is/are:
Disprortional periosteal and endosteal bone formation
58) What is concentrated at the fott end plate of an axon:
Mitochondria.<br/>(C)Nissl's granules
59) The histological abnormality in Multiple myeloma is/are:
Defective bone formation and increased resorption
60) All of the following elements undergoe assembly and disassembly in
mammalian cells ,Except:
a) Myosin
b) Actin
c) Titin
61) What induces formation of multinucleated osteoclast:
a) RANKL
b) Osteoprotegerin
c) M-CSF
d) all true
62) To which element hydroxyapatite binds to result in mineralization in
Bone:
Osteocalcin
63) All muscle types share which common feature:
a) Myosin and actin contractile proteins
b) Striated appearance
c) slow contraction
64) Which element binds the contractile protein in skeletal muscle to Z-
line:
a) Alfa actinin
b) Myomesin
c) M-protein
65) Intermediate filaments that hold the myofibrils In-register with each
other by:
Anchorage of desmin and vimentin to Z-lines
66) Gamma fibers innervates:
a) Striated portion of intrafusal fiber
b) nonstriated portion of extrafusal fibers
67)What factors regulate skeletal muscule contraction:
a)Sarcomer lengh regulation only
b)Cap-Z and tropomodulin
c) Motor nerve supply
d) Muscle spindle
All the listed
68) Cardiac muscle and skeletal muscle fibers share the following
characteristics EXCEPT:
a. Presence of gap junctions
b. striated in appearance
c. Both skeletal and cardiac muscle tissues possess intercalated discs
69) The following statements concerning skeletal muscle cells are
correct EXCEPT:
Multi-nuclei of fiber result from the successive division of myoblasts
70) Cross striation is due to:
Both in-register arrangment of contractile proteins and myofibril with
each other
71) Caveoli in smooth muscle represent:
Site of calcium aggregate
72) Which of the following muscles may undergo physiological
hypertrophy or hyperplasia:
a) Smooth muscle
b) Cardiac muscles
c) Skeletal muscles
73) Rigor mortis results from:
a) Stable actin -myosin interaction due to lack of ATP
b) Stable actin -myosin interaction due to excess ATP
