Mindanao State University – Iligan Institute of Technology Student: SALIMBAGAT, CHRISTINE.

P Section: 262
COLLEGE OF NURSING

PHARMACOLOGY DRUG STUDY

Brand Name: Tenormin Generic Name: Atenolol Drug Classification: Beta blockers
Dosage,
Route &
Drug-Drug & Drug-Food Indication Side Effects Adverse Reactions (By
Frequency Drug Action Contraindications
Interactions s (By System) System)
Recommend
ed
Hypertension In therapeutic doses, atenolol Drug: Atropine and Manageme Sinus bradycardia, greater than first- CNS: fatigue, weakness, anxiety, CNS: Dizziness, vertigo,
Angina selectively blocks beta1- other ANTICHOLINERGICS  nt of degree AV heart block, depression, dizziness, drowsiness, light-headedness,
Adult: PO 25 adrenergic receptors located may increase atenolol hypertensi uncompensated heart failure, insomnia, memory loss, mental syncope, fatigue or
–50 mg/d, chiefly in cardiac muscle. With absorption from GI on as a cardiogenic shock, peripheral status changes, nervousness, weakness, lethargy,
may increase large doses, preferential effect tract; NSAIDS may single vascular disease, Raynaud's disease, nightmares. drowsiness, insomnia,
to 100 mg/d is lost and inhibition of beta2- decrease hypotensive agent or hypotension; abrupt discontinuation, EENT: blurred vision, stuffy nose. mental changes,
Child: PO 0.8 adrenergic receptors may lead effects; may mask concomita pulmonary edema. Safety during Resp: bronchospasm, wheezing. depression. 
–1.5 mg/kg/d to increased airway resistance, symptoms of a ntly with pregnancy (category D), or lactation CV: BRADYCARDIA, HF, CV: Bradycardia,
(max: 2 especially in patients with hypoglycemic reaction other is not established. PULMONARY EDEMA, hypotension, CHF, cold
mg/kg/d) asthma or COPD. Mechanisms induced antihyperte Cautious Use hypotension, peripheral extremities, leg pains,
MI for antihypertensive action by insulin, SULFONYLUREA nsive Hypertensive patients with CHF vasoconstriction. dysrhythmias. 
Adult: PO 10 include central effect leading to S; may agents, controlled by digitalis and diuretics, GI: constipation, diarrhea,qliver GI: Nausea, vomiting,
min after decreased sympathetic outflow increase lidocaine levels especially a vasospastic angina (Prinzmetal's enzymes, nausea, vomiting. diarrhea. 
second IV to periphery, reduction in renin and toxicity; diuretic, angina); asthma, bronchitis, GU: erectile dysfunction,plibido, Respiratory: Pulmonary
dose, start 50 activity with consequent pharmacologic and toxic and in emphysema, and COPD; major urinary frequency. edema,
mg/d IV 5 mg suppression of the renin- effects of both atenolol treatment depression; diabetes mellitus; Derm: rashes. Endo: dyspnea, bronchospasm
q5min times angiotensin-aldosterone and verapamil are of stable impaired renal function, dialysis; hyperglycemia, hypoglycemia. Other: May mask
2 doses, then system, and competitive increased. Prazosin, terazo angina myasthenia gravis; MS: arthralgia, back pain, joint symptoms of
switch to PO inhibition of catecholamine cin may increase severe pectoris, pheochromocytoma, pain. hypoglycemia;
binding at beta-adrenergic hypotensive response to MI. hyperthyroidism, thyrotoxicosis; Misc: drug-induced lupus decreased sexual ability.
receptor sites. first dose of atenolol. older adults. syndrome.
Responsibilities in the Nursing Process (ADPIE) Responsibilities in the Nursing Process (ADPIE)
A - ● Monitor BP, ECG, and pulse frequently during dosage adjustment period P - ● To decrease BP. ● To reduce frequency of angina. ● To increase activity tolerance. ● Prevent MI.
and periodically throughout therapy. ● Monitor intake and output ratios and I - PO: Take apical pulse before administering drug. If 50 bpm or if arrhythmia occurs, withhold medication and notify
daily weights. Assess for HF (dyspnea, rales/crackles, weight gain, peripheral physician or other health care professional● Advise patients to change positions slowly to minimize orthostatic
edema, jugular venous distention). ● Assess frequency,characteristics of angina hypotension.
D - ●Decreased cardiac output(Side Effects)●Noncompliance(Patient/FamilyT) E - ● Decrease in BP. ● Reduction in frequency of angina. ● Increase in activity tolerance. ● Prevention of MI.

Reference: Vallerand, A. H., Sanoski, C. A., & Deglin, J. H. (n.d.). Davis's Drug Guide for Nurses Fourteenth Edition. Retrieved October 19, 2019, from
https://davisplus.fadavis.com/3976/meddeck/pdf/atenolol.pdf