Scribd
Upload
30 views1 page

Cancer: Further Information

Viruses from several families including DNA and RNA viruses can cause cancer in humans and other species. Only a minority of infected individuals develop viral cancers, which are determined by host and viral genetic factors. Accepted human cancer viruses include certain HPV and hepatitis virus genotypes, EBV, KSHV, HTLV, and recently discovered Merkel cell polyomavirus which causes a rare skin cancer. Hepatitis viruses can lead to liver cancer, while HTLV and human papillomaviruses cause other cancers. Within the herpesvirus family, KSHV causes Kaposi's sarcoma and EBV causes lymphomas.

Uploaded by

razvan
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
30 views1 page

Cancer: Further Information

Viruses from several families including DNA and RNA viruses can cause cancer in humans and other species. Only a minority of infected individuals develop viral cancers, which are determined by host and viral genetic factors. Accepted human cancer viruses include certain HPV and hepatitis virus genotypes, EBV, KSHV, HTLV, and recently discovered Merkel cell polyomavirus which causes a rare skin cancer. Hepatitis viruses can lead to liver cancer, while HTLV and human papillomaviruses cause other cancers. Within the herpesvirus family, KSHV causes Kaposi's sarcoma and EBV causes lymphomas.

Uploaded by

razvan
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
You are on page 1/ 1

Cancer

Further information: Oncovirus


Viruses are an established cause of cancer in humans and other
species. Viral cancers occur only in a minority of infected persons (or
animals). Cancer viruses come from a range of virus families, including
both RNA and DNA viruses, and so there is no single type of "oncovirus"
(an obsolete term originally used for acutely transforming retroviruses).
The development of cancer is determined by a variety of factors such as
host immunity[190] and mutations in the host.[191] Viruses accepted to cause
human cancers include some genotypes of human papillomavirus,
hepatitis B virus, hepatitis C virus, Epstein–Barr virus, Kaposi's sarcoma-
associated herpesvirus and human T-lymphotropic virus. The most
recently discovered human cancer virus is a polyomavirus (Merkel cell
polyomavirus) that causes most cases of a rare form of skin cancer
called Merkel cell carcinoma.[192] Hepatitis viruses can develop into a
chronic viral infection that leads to liver cancer.[193][194] Infection by human
T-lymphotropic virus can lead to tropical spastic paraparesis and adult T-
cell leukaemia.[195] Human papillomaviruses are an established cause of
cancers of cervix, skin, anus, and penis.[196] Within the Herpesviridae,
Kaposi's sarcoma-associated herpesvirus causes Kaposi's sarcoma and
body-cavity lymphoma, and Epstein–Barr virus causes Burkitt's
lymphoma, Hodgkin's lymphoma, B lymphoproliferative disorder, and
nasopharyngeal carcinoma.[197] Merkel cell polyomavirus closely related to
SV40 and mouse polyomaviruses that have been used as animal models
for cancer viruses for over 50 years.[198]

You might also like