DRUG STUDY
Classification Mechanism of Indication Contraindicat Adverse Effects Nursing
Drug Action ion Responsibiliti
es
Generic Therapeutic Interferes with Moderate >Hypersensit CNS: headache, ● Monitor
Name: class: Anti- bacterial cell- to severe ivity to hyperactivity, patient for
Cefuroxime infective wall synthesis infections, cephalospori hypertonia, life-
and division by including ns seizures threatening
Pharmacologic binding to cell those of or penicillins GI: nausea, vomiting, adverse
Brand Name: al: wall, causing skin, bone, diarrhea, effects,
altoxime Second cell to die. joints, abdominal pain, including
generation Active against urinary or >Carnitine dyspepsia, anaphylaxis
Dosage: cephalosporin gram-negative respiratory deficiency pseudomembranous ● Monitor
Adults and and gram- tract, colitis neurologic
children ages positive gynecologic GU: hematuria, status,
12 and older: bacteria, with infections vaginal candidiasis, particularly
750 mg to 1.5 expanded renal dysfunction, for signs of
g I.M. or I.V. q activity acute renal failure impending
8 hours against gram- Hematologic: seizures.
for 5 to 10 negative hemolytic anemia, > Monitor
days or 250 to bacteria. aplastic anemia, temperature;
500 mg P.O. q hemorrhage watch for
12 hours signs and
Children ages INTERACTION symptoms of
3 months to Drug-drug. Antacids superinfection
12 years: containing .
50 to 100 aluminum or ● Advise
mg/kg/day I.V. magnesium, patient to
or I.M. in histamine2- immediately
divided doses receptor antagonists: report
q 6 to 8 hours increased rash or
cefuroxime bleeding
Route: absorption tendency.
Oral Probenecid: ● Instruct
decreased excretion patient to
Frequency: and take drug with
Twice a day increased blood level food
of cefuroxime ● Teach
Drug-food. patient how to
Moderate- or high-fat recognize
meal: increased drug signs
bioavailability and
symptoms of
superinfection
.
DRUG STUDY
Drug Classificati Mechanism of Indication Contraindication Adverse Effects Nursing
on Action Responsibiliti
es
Generic Therapeuti Destroys > Respiratory >Hypersensitivit >CNS: lethargy, > Monitor for
Name: c class: bacteria by tract, skin, y to penicillin, hallucinations, seizures
Ampicillin Anti- inhibiting and soft cephalosporins, anxiety, agitation, when giving
infective bacterial tissue imipenem, or fatigue, seizures high doses.
Brand Name: cell-wall infections other >CV: vein irritation, > Monitor for
Apitrex Pharmacol synthesis caused by beta-lactamase thrombophlebitis, bleeding
ogical: during Hemophilus inhibitors heart failure tendency or
Dosage: Aminopenic microbial influenzae, EENT: blurred vision, hemorrhage.
Adults and illin multiplication staphylococc itchy eyes > Advise
children iand >GI: abdominal pain, patient to
weighing 40 streptococci enterocolitis, minimize GI
kg gastritis, upset
(88 lb) or stomatitis, glossitis, by eating
more: 250 to black “hairy” small,
500 mg I.V. or tongue, furry tongue, frequent
I.M. q 6 hours oral or rectal servings of
Adults and candidiasis, food and
children pseudomembranous drinking
weighing less colitis plenty of
than 40 kg (88 >GU: vaginitis, fluids.
lb): 25 to 50 nephropathy, > Instruct
mg/kg/day interstitial patient to
I.M. or I.V. in nephritis immediately
divided doses INTERACTION report signs
q 6 to 8 Drug-drug. and
hours Allopurinol: increased symptoms of
Adults and risk hypersensitiv
children of rash ity
weighing Chloramphenicol: reaction,
more synergistic or such as rash,
than 20 kg (44 antagonistic fever,
lb): 250 mg effects or chills.
P.O. q Hormonal
6 hours contraceptives:
Children decreased
weighing 20 contraceptive effect,
kg (44 lb) or increased risk of
less: 50 breakthrough
mg/kg/day bleeding
P.O. Probenecid:
decreased renal
Route: P.O, excretion
I.V, I.M of ampicillin,
increased ampicillin
Frequency: blood level
Every 6 hours Tetracyclines:
reduced bactericidal
effect
DRUG STUDY
Drug Classification Mechanism of Indication Contraindicat Adverse Nursing
Action ion Effects Responsibiliti
es
Generic Therapeutic: ant The B-complex To treat and Sensitivity to CNS: >instruct
Name: Vitamin anemics, food vitamins act as prevent any of the Headache, client to
B complex supplements coenzyme and vitamin ingredients dizziness, report
are essential deficiency included in insomnia, unusualities
Pharmacological: for the the fatigue, >ensure
Brand Name: Multivitamins metabolism of medication tiredness, safety
Aduvit proteins, pruritus, >monitor
carbohydrates stomatitis accordingly
Patient’s and fatty acids GI: Dyspepsia, >document
Dosage: GI pain, all relevant
1 tab diarrhea, data
Route: vomiting
P.O GU: Dysuria,
Frequency: renal
Once a day impairment
Timing:
INTERACTION
Drug to Drug:
Ascorbic acid:
absorption
Chlorampheni
col:
hematologic
response
Colchicine,
amino salicylic
acid,
climetidine,
excess
Alcohol:
absorption/effe
ctiveness
DRUG STUDY
Drug Classification Mechanism of Indication Contraindication Adverse Nursing
Action Effects Responsibilities
Generic Therapeutic: An essential Prevention Hemochromatos CNS: >monitor blood
Name: Vitamins & mineral found and treatment is, Seizures, studies of the
Multivitamins + minerals in hemoglobin, of iron-vitamin hemosiderosis, dizziness, patient
FeSO4 antianemics myoglobin, and dietary or other headache, >inform patients
and many deficiency evidence of iron syncope about possible
Brand Name: enzymes. anemia due to overload; adverse effect
OB-care Enters the blood loss anemias not due CV: that may occur
Dosage: Pharmacolo bloodstream during to iron hypotension, >observe proper
750 mg gic: Water- and is menstruation, deficiency hypertension dose of
Route: soluble transported to infection, , tachycardia medication
P.O. vitamins, iron the organs of surgery, INTERACTION
Frequency: supplements the delivery, Drug-Drug: GI: Nausea,
reticuloendoth intoxications, antacids that constipation,
Timing: ellal system parasitosis, or contain calcium dark stools,
(liver, spleen, other causes tetracyclines, vomiting
bone marrow), &anemias biphosphate,
where it is during proton-pump
separated out pregnancy inhibitors
and becomes
part of iron Drug-food: iron
stores absorption is
decreased 33-
50% by
concurrent
administration of
food
DRUG STUDY
Drug Classification Mechanism of Indication Contraindication Adverse Effects Nursing
Action Responsibilities
Generic Pharmacolo Actinomycin Osteo-D Hypersensitivity >monitor blood
Name: gical: D, an (Calcium to any studies of the
Calcium- Calcium Salt; inhibitor of Carbonate) component of patient
Vitamin D Electrolyte DNA‐directed acetate is a the formulation; >inform patients
Supplement, RNA phosphate hypophosphate about possible
Brand Name: Oral; synthesis, binder mia, adverse effect
Osteo-D Vitamin, Fat inhibits indicated to hypercalcemia, that may occur
Soluble the action of reduce evidence of >observe proper
Dosage: vitamin D in serum vitamin D dose of
mediating phosphorus toxicity; history medication
Route: intestinal in patients of kidney stones >ensure safety
P.O calcium with end
Frequency: absorption stage renal Interaction
Twice a day and bone disease Drug-drug:
for 2 months resorption. (ESRD). Cefpodoxime:
Timing: Vitamin D als Antacids may
o stimulates decrease the
messenger‐ serum
RNA concentration of
synthesis in Cefpodoxime.
intestinal Food: Food may
mucosa increase
within 1/2 hr. calcium
of vitamin absorption.
treatment. Calcium may
decrease iron
absorption.
Bran, foods high
in oxalates, or
whole grain
cereals may
decrease
calcium
absorption.
DRUG STUDY
Drug Classification Mechanism Indication Contraindication Adverse Nursing
of Action Effects Responsibilities
Generic Potassium You should not use Confusion,
Name: citrate is potassium citrate if Increased
Potassium used to treat you have kidney thirst, Black
citrate a kidney stone failure, a urinary or tarry
condition tract infection, stools,
Brand Name: called renal uncontrolled Irregular
Tascit tubular diabetes, a peptic
heartbeat,
acidosis. ulcer in your
Leg
Dosage: stomach, Addison's
disease, severe discomfort,
Route: burns or other Muscle
tissue injury, if you weakness,
Frequency: are dehydrated, if Coughing up
you take certain blood
Timing: diuretics (water
pills), or if you have
high levels of GI: nausea,
potassium in your vomiting,
blood diarrhea,
(hyperkalemia). abdominal
INTERACTION pain
Drug-drug:
Aluminum
Hydroxide: Citric
Acid Derivatives
may increase the
absorption of
Aluminum
Hydroxide.
DRUG STUDY
Drug Classification Mechanism of Indication Contraindication Adverse Effects Nursing
Action Responsibilit
Generic Pharmacolog Anti- Mefenamic Contradiction with CNS: headache, >do not
Name: ic: Anti- inflammatory; acid is given hypertensive to dizziness, administer wit
Mefenamic inflammatory analgestic, to patient to mefenamic acid, insomnia anticoagulants
acid Drug and relief of aspirin allergy, and GI: nausea, GI and another d
(NSAID) antipyretic acute to as treatment of pain, diarrhea, that causes G
activities moderately perioperative pain Constipation upset
Brand Name: related to pain with coronary artery GU: dysuria, >monitor adve
Almefen inhibition of bypass grafting renal effect
prostaglandin impairment >instruct
Dosage: synthesis; Interaction Other: discontinuatio
500mg exact >drug-drug: peripheral medication if
Route: mechanism increased risk of GI edema, adverse effect
Oral of action are bleeds with ASA, anaphylactoid to occurs
Frequency: not known anticoagulants, reactions to >symptomatic
Every 6 hours other NSAIDs anaphylactic management
pnr >drug-lab-test false shoch non-serious s
Timing: positive reaction for effect
urinary bile using
the Diazo tablet test
