DRUG STUDY: NCM 106 PHARMACOLOGY Instructor: SIR IVAN CRUZ Date: ________________________
NAME: SANTOS, LORE ANNE MHAE T. BLOCK and Year:___________________________Group: ______________________________
DRUG NAME MECHANISM OF INDICATION CONTRAINDICATION ADVERSE EFFECTS NURSING
ACTION INTERVENTIONS
decreases inflammation via · Replacement therapy in · Contraindicated with Vertigo, headache, Administer once-a-day doses
suppression of the migration adrenal cortical insufficiency infections, especially paresthesias, insomnia, before 9 AM to mimic normal
Generic Name: of polymorphonuclear tuberculosis, fungal convulsions, psychosis, peak corticosteroid blood
leukocytes and reversing · Hypercalcemia associated infections, amebiasis, vaccinia cataracts, increased levels.
increased capillary with cancer and varicella, and antibiotic- intraocular pressure,
permeability. It also resistant infections; lactation. glaucoma (long-term therapy) · Increase dosage when
· Short-term management of patient is subject to stress.
suppresses the immune various inflammatory and Hypotension, shock,
Prednisone system by reducing the allergic disorders, such as hypertension and CHF · Taper doses when
activity and the volume of the rheumatoid arthritis, collagen secondary to fluid retention, discontinuing high-dose or
immune system. diseases (eg, SLE), thromboembolism, long-term therapy.
dermatologic diseases thrombophlebitis, fat · Do not give live virus
embolism, cardiac
(eg, pemphigus), status vaccines with
arrhythmias
asthmaticus, and autoimmune immunosuppressive doses of
Drug Classification:
disorders corticosteroids.
· Hematologic disorders:
thrombocytopenia purpura,
erythroblastopenia
SAIDS
· Ulcerative colitis, acute
exacerbations of multiple
sclerosis and palliation in
some leukemias and
lymphomas
· Trichinosis with neurologic
or myocardial involvement
Available Dosage:
5-60 mg
DRUG NAME MECHANISM OF INDICATION CONTRAINDICATION ADVERSE EFFECTS NURSING
ACTION INTERVENTIONS
Unbound glucocorticoids Arthritis Hypersensitivity Hypertension Assess for potassium
cross cell membranes and Blood disorders Hypokalemia/ Mental disorders depletion (fatigue, nausea,
Generic Name: bind with high affinity to vomiting, depression,
Severe allergic reactions hypocalcemia Ulcer disease
specific cytoplasmic Exacerbation, polyuria, dysrhythmia and
receptors, modifying Certain cancers Systemic fungal infections pancreatitis; weakness). - Assess for
transcription and protein Immune system disorders Latent or active TB Glucose tolerance hypertension, oedema and
synthesis. By this mechanism, Shock Herpes simplex infection disorders cardiac symptoms. - Assess
glucocorticoids can inhibit Latent or active peptic Glucose serum level for mental status. - Rotate
Methylprednisolone
leukocyte infiltration at the ulcer elevation sites in IM injection
site of inflammation, interfere Osteoporosis Cushing-like syndrome,
with mediators of Amenorrhoea,
Hypertension
inflammatory response, and Rash, contact dermatitis,
Avoid live virus vaccines
suppress humoral immune
Drug Classification: Steroidal acne
responses. The
Moon-like face
antiinflammatory actions of
Edemas
corticosteroids are thought to
Increased potassium
involve phospholipase A2
excretion
inhibitory proteins,
SAIDS Muscular weakness,
lipocortins, which control the
biosynthesis of potent Osteoporosis
mediators of inflammation
such as prostaglandins and
leukotrienes.
Available Dosage:
125mg/2ml vial
