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The document describes how a pathogenic microorganism causes diarrhea by disrupting intestinal cells and stimulating fluid secretion and motility changes, leading to dehydration if fluid losses are not replaced.

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Elle Reyes
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30 views1 page

PP

The document describes how a pathogenic microorganism causes diarrhea by disrupting intestinal cells and stimulating fluid secretion and motility changes, leading to dehydration if fluid losses are not replaced.

Uploaded by

Elle Reyes
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOC, PDF, TXT or read online on Scribd
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Pathogenic microorganism (Entamoeba histolytica) enters the system

Microorgansim releases endotoxins

Hyperstimulation/ irritation of intestinal lining

Disruption of cell membrane

Increased water and electrolyte secretion Release of chemical mediators

Active secretion of Chloride and bicarbonate ions Activation of nociceptors

Inhibition of Sodium and Water reabsorption Nerve impulse sent to CNS

Increased Protein-rich fluid secretion CNS response: Vasodilation,

Increased cell permeability

Abdominal pain

Overwhelms large bowel’s ability to reabsorb fluids

Increased fluid volume and decreased intestinal motility Abdominal distention

Watery stools (Diarrhea), Hyperactive bowel sounds Stimulation of vomiting center in the brain

Nausea, Anorexia

Continuous active fluid losses, Decreased food and fluid intake

Inadequate hydration and nutrition

Dry lips and mucous membranes, Sunken eyeballs, Poor skin turgor

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