DISORDERS OF MENSTRUATION &
DISORDERS OF THE UTERUS
          By C Settley
Dysmenorrhoea
■ Primary dysmenorrhea is common menstrual cramps
  that are recurrent (come back) and are not due to other
  diseases.
■ Secondary dysmenorrhea is pain that is caused by a
  disorder in the woman's reproductive organs, such as
  endometriosis, adenomyosis (A condition in which endometrial tissue exists within
  and grows into the uterine wall), uterine fibroids, or infection.
■ Pain from secondary dysmenorrhea usually begins
  earlier in the menstrual cycle and lasts longer than
  common menstrual cramps.
 2018/10/02   Compiled by C Settley                                                   2
Management
■ Analgesics
■ Place a heating pad or hot water bottle
■ Rest
■ Avoid foods that contain caffeine
■ Avoid smoking and drinking alcohol
■ Massage of lower back and abdomen
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Premenstrual tension
■ A group of symptoms that occur in women, typically between ovulation and a period.
2018/10/02   Compiled by C Settley                                                     4
Premenstrual tension
■ The cause isn't fully understood but likely involves
  changes in hormones during the menstrual cycle.
■ Symptoms include mood swings, tender breasts, food
  cravings, fatigue, irritability and depression.
■ Lifestyle changes and medication may reduce
  symptoms.
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Remember that….
■ The menstrual cycle is the monthly series of changes a woman's
  body goes through in preparation for the possibility of pregnancy.
■ Each month, one of the ovaries releases an egg — a process
  called ovulation.
■ At the same time, hormonal changes prepare the uterus for
  pregnancy.
■ If ovulation takes place and the egg isn't fertilized, the lining of
  the uterus sheds through the vagina.
■ This is a menstrual period.
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Amenorrheoa
■ Primary Amenorrhea is the absence of a menstrual
  period in a woman of reproductive age.
■ Secondary amenorrhea is the absence of menstrual
  bleeding in a woman who had been menstruating but
  later stops menstruating for three or more months in
  the absence of pregnancy, lactation (production of
  breast milk), cycle suppression with systemic hormonal
  contraceptive (birth control) pills, or menopause.
■ In primary amenorrhea, menstrual periods have never begun (by age 16), whereas
  secondary amenorrhea is defined as the absence of menstrual periods for three
  consecutive cycles or a time period of more than six months in a woman who was
  previously menstruating.
2018/10/02   Compiled by C Settley                                                 7
Amenorrheoa: Causes
■ Absent menstruation, or amenorrhea, is the absence of
  menstrual bleeding.
■ Lifestyle factors, including body weight and exercise
  levels, stress.
■ In some cases, hormonal imbalances or problems with
  the reproductive organs might be the cause.
■ Emergency contraceptives.
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Amenorrheoa: Management
■ Birth control pills or other types of hormonal medication.
■ Certain oral contraceptives may help restart the menstrual
  cycle.
■ Medications to help relieve the symptoms of PCOS.
   – A hormonal disorder causing enlarged ovaries with small
     cysts on the outer edges.
■ Oestrogen replacement therapy (ERT).
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Menorrhagia
■ Abnormally heavy bleeding at menstruation.
■ Prolonged
■ Excessive
■ Hormonal imbalances’
■ Causes:
   – Fibroids (Non-cancerous growths in the uterus that can develop during a woman's
             childbearing years)
      – Intra uterine contraceptive device
      – Pelvic inflammatory disease (An infection of the female reproductive organs)
      – Blood-clotting factors (Some of the contributing factors of blood clotting include
             cigarette smoking, advanced age, obesity, major surgery, sickle cell anaemia, use of
             estrogen supplements, lack of physical activity, and injury)
2018/10/02         Compiled by C Settley                                                            10
Menorrhagia: Management
■ Monitor blood loss
■ Pad usage
■ Anaemia
■ Underlying cause
■ Combined oral contraceptives
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Metrorrhagia
■ Irregular vaginal bleeding between menstrual periods
■ Needs urgent attention
■ Metrorrhagia may be a sign of an underlying disorder, such as hormone imbalance,
  endometriosis, uterine fibroids or, less commonly, cancer of the uterus.
■ Metrorrhagia may cause significant anaemia.
2018/10/02   Compiled by C Settley                                                   12
Polymenorrhoea
■ The average menstrual cycle is 28 days long. Cycles can range anywhere from 21 to 35
  days in adults and from 21 to 45 days in young teens.
■ Polymenorrhoea is the medical term for cycles with intervals of 21 days or fewer.
■ Causes:
   – Stress
   – STD’s
   – Menopause
   – Endometriosis
   – Other causes include hyperactivity of the anterior pituitary gland causing frequent
      ovulation, malnutrition, chronic pelvic inflammation, and very rarely, cancer of the
      female reproductive organs.
   – shortening of the follicular phase (first phase of the cycle), and the corpus luteum
      phase flows regularly
   – shortening of the luteal phase (the second phase of the cycle)
2018/10/02    Compiled by C Settley                                                          13
Phases of the normal menstrual cycle
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Postmenopausal bleeding
■ Occurs at least 6 months after menopause
■ Associated with malignancy
■ Must be investigated urgently
■ Health info:
   – Report vaginal bleeding not in line with menstruation cycle
   – Imbalance in hormones- must be attended to urgently
   – Menstrual calendar
   – Diet must be rich in protein and iron to prevent anaemia
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Menopause
■ A natural decline in reproductive hormones when a woman reaches her 40s
  or 50s.
■ Common symptoms include hot flashes and vaginal dryness. There may also
  be sleep disturbances. The combination of these symptoms can cause
  anxiety or depression.
■ Menopause is a natural process with treatments that focus on symptomatic
  relief. Vaginal dryness is treated with topical lubricants or oestrogen.
  Medications can reduce the severity and frequency of hot flushes. In special
  circumstances, oral hormone therapy may be used.
2018/10/02   Compiled by C Settley                                               16
Menopause:
Nursing management
■ Psychological issues
■ Feelings of loss
■ At risk for developing cancers
■ Sensitive to feelings
■ Support
■ Nutrition
■ Exercise
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Menopause:
Pharmacological management
■ Hormone replacement therapy
   – Estrogen supplementation benefits: lowers risk of developing heart
      disease
   – Protect against osteoporosis—bone loss that increases with age—
      especially after menopause.
■ Hot flushes
   – Women of all ages may have low estrogen, and they don't always
      have hot flashes. Rather, it's the decrease in estrogen during
      menopause that experts believe to be the cause of hot flashes
■ Promote comfort
■ Bone loss as explained above
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Menopause:
Essential health information
■   Diet
■   Water intake
■   Breast self examinations
■   Report findings
■   Prescribed medication
■   Osteoporosis
     – A condition in which bones become weak and brittle.
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  Endometriosis
■ A disorder in which tissue that normally lines the uterus grows outside the uterus.
■ Rare condition because the endometrium is shielded from bacteria by:
   – The acid barrier of the vagina
   – The cervical mucus plug
         ■   The mucus plug serves to protect the uterus and the fetus by preventing bacteria from entering the
             uterus. The mucus plus can be clear or slightly pink in color and can be tinged with brown or red
             blood. As the cervix slowly begins to dilate prior to the onset of labor, the mucus plug is expelled.
    – The constant shedding of the endometrium with each menstrual period
      2018/10/02       Compiled by C Settley                                                                         20
Endometriosis: Symptoms
■ Painful periods (dysmenorrhea).
   – Pelvic pain and cramping may begin before the period and extend several days into
       the period
   – Lower back and abdominal pain are common.
■ Pain with intercourse.
   – Pain during or after sex is common with endometriosis.
■ Pain with bowel movements or urination.
■ Excessive bleeding.
■ Infertility.
    – Endometriosis is first diagnosed in some women who are seeking treatment for
        infertility.
■ Other symptoms
   – fatigue, diarrhoea, constipation, bloating or nausea, especially during menstrual
       periods.
2018/10/02    Compiled by C Settley                                                      21
Endometriosis: Causes
■   Retrograde menstruation.
     – Flowback of cells in the fallopian tubes.
■   Transformation of peritoneal cells.
      – When peritoneal cells — cells that line the inner side of your abdomen are transformed into
          endometrial cells.
■   Embryonic cell transformation.
     – Hormones such as estrogen may transform embryonic cells — cells in the earliest stages of
        development — into endometrial cell implants during puberty.
■   Surgical scar implantation.
     – After a surgery, such as a hysterectomy or C-section, endometrial cells may attach to a
          surgical incision.
■   Endometrial cells transport.
     – The blood vessels or tissue fluid (lymphatic) system may transport endometrial cells to other
        parts of the body.
■   Immune system disorder.
      – It's possible that a problem with the immune system may make the body unable to recognize
        and destroy endometrial tissue that's growing outside the uterus.
2018/10/02      Compiled by C Settley                                                                  22
Endometriosis: Risk factors
■   Never giving birth
■   Starting of period at an early age
■   Going through menopause at an older age
■   Short menstrual cycles — for instance, less than 27 days
■   Having higher levels of oestrogen in the body or a greater lifetime exposure to oestrogen the body
    produces
■   Low body mass index
■   Alcohol consumption
■   Hereditary
■   Any medical condition that prevents the normal passage of menstrual flow out of the body
■   Uterine abnormalities
■   Complications: infertility and ovarian cancer
2018/10/02       Compiled by C Settley                                                                   23
Endometriosis: Management
■ Analgesics
■ Contraceptives
■ Pregnancy
■ Hormone therapy
■ Hysterectomy
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Ovarian cysts
■ A solid or fluid-filled sac or pocket (cyst) within or on the surface of an ovary.
2018/10/02     Compiled by C Settley                                                   25
Ovarian cysts
Symptoms
■ Most cysts don't cause symptoms and go away on their own. However, a large
  ovarian cyst can cause:
■ Pelvic pain — a dull or sharp ache in the lower abdomen on the side of the cyst
■ Fullness or heaviness in your abdomen
■ Bloating
2018/10/02    Compiled by C Settley                                                 26
Ovarian cysts
Risk factors
■ Hormonal problems.
   – Fertility drugs.
■ Pregnancy.
   – Sometimes, the cyst that forms when ovulating stays on the ovary throughout a
       pregnancy.
■ Endometriosis.
   – This condition causes uterine endometrial cells to grow outside the uterus. Some of
      the tissue can attach to the ovary and form a growth.
■ A severe pelvic infection.
   – If the infection spreads to the ovaries, it can cause cysts.
■ A previous ovarian cyst.
   – likely to develop more if had before.
2018/10/02    Compiled by C Settley                                                    27
Ovarian cysts
Complications
■ Ovarian torsion.
   – Cysts that enlarge can cause the ovary to move, increasing the chance of
       painful twisting of your ovary (ovarian torsion). Symptoms can include an
       abrupt onset of severe pelvic pain, nausea and vomiting. Ovarian torsion can
       also decrease or stop blood flow to the ovaries.
■ Rupture.
   – A cyst that ruptures can cause severe pain and internal bleeding. The larger
      the cyst, the greater the risk of rupture. Vigorous activity that affects the pelvis,
      such as vaginal intercourse, also increases the risk.
2018/10/02    Compiled by C Settley                                                       28
Ovarian cysts
Diagnosis & Treatment
■ Pregnancy test.
   – A positive test might suggest a cyst.
■ Pelvic ultrasound.
   – A wand like device (transducer) sends and receives high-frequency sound waves
       (ultrasound) to create an image of the uterus and ovaries on a video screen.
■ Laparoscopy.
   – Using a laparoscope — a slim, lighted instrument inserted into the abdomen
      through a small incision.
■ CA 125 blood test.
   – Blood levels of a protein called cancer antigen 125 (CA 125) often are elevated in
      women with ovarian cancer. If the cyst is partially solid and the patient is at high
      risk of ovarian cancer, your doctor might order this test.
   – Elevated CA 125 levels can also occur in noncancerous conditions, such as
      endometriosis, uterine fibroids and pelvic inflammatory disease.
2018/10/02    Compiled by C Settley                                                          29
Ovarian cysts
Diagnosis & Treatment
■ The doctor will likely recommend that the patient gets a follow-up pelvic ultrasound
  at intervals to see if the cyst changes in size.
■ Medication.
■ Surgery.
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    Diagnostic tests: Mammogram
■ Mammography is the process of using low-energy X-rays to examine the human
  breast for diagnosis and screening. The goal of mammography is the early detection
  of breast cancer, typically through detection of characteristic masses or micro
  calcifications.
    2018/10/02    Compiled by C Settley                                                31
    Diagnostic tests: Ultrasound
■ Ultrasound is sound waves with frequencies higher than the upper audible limit of
  human hearing. Ultrasound is not different from "normal" sound in its physical
  properties, except in that humans cannot hear it.
     2018/10/02   Compiled by C Settley                                               32
     Diagnostic tests: Biopsy
■ A biopsy is a medical test commonly performed by a surgeon, interventional
  radiologist, or an interventional cardiologist involving extraction of sample cells or
  tissues for examination to determine the presence or extent of a disease.
     2018/10/02    Compiled by C Settley                                                   33
Fibrocystic breast
■ Changes that give a breast a lumpy or ropelike texture.
■ Fibrocystic: characterized by the development of fibrous tissue and cystic spaces,
  typically in the pancreas or the breast.
2018/10/02    Compiled by C Settley                                                    34
Fibrocystic breast: Causes
■ Fluctuating hormone levels during the menstrual cycle
  can cause breast discomfort and areas of lumpy breast
  tissue that feel tender, sore and swollen.
■ Fibrocystic breast changes tend to be more bothersome
  before your menstrual period, and the pain and
  lumpiness tends to clear up or lessen once your
  menstrual period begins.
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Fibrocystic breast: Symptoms
■ Breast lumps or areas of thickening that tend to blend into the surrounding breast
  tissue
■ Generalized breast pain or tenderness
■ Breast lumps that fluctuate in size with the menstrual cycle
■ Green or dark brown nonblood nipple discharge that tends to leak without pressure
  or squeezing
■ Breast changes that are similar in both breasts
■ Monthly increase in breast pain or lumpiness from midcycle (ovulation) to just before
  your period
2018/10/02    Compiled by C Settley                                                    36
Fibrocystic breast:
Diagnosis & treatment
■ Breast exam
■ Ultrasound
■ Mammogram
■ Fine needle aspiration
■ Breast biopsy
■ Biopsy is the procedure to remove a small amount of suspicious tissue from the breast
  with a larger “core” (meaning “hollow”) needle. It is usually performed while the patient
  is under local anesthesia, meaning the breast is numbed. As with fine-needle aspiration,
  this may involve ultrasound.
      –      Home remedies, evening primrose oil & Vit E
2018/10/02        Compiled by C Settley                                                       37
Fibro adenoma
■ A non-cancerous breast tumour that most often occurs in young women.
■ Reproductive hormones may cause fibroadenomas.
■ A fibroadenoma feels like a firm, smooth or rubbery lump in the breast with a well-
  defined shape. It's painless and moves easily when touched. Although healthy
  breast tissue often feels lumpy, a new lump or change in the breasts should be
  looked at by a doctor.
■ Treatment may include monitoring for changes in the size or feel, a biopsy to
  evaluate it or surgery to remove it.
2018/10/02    Compiled by C Settley                                                     38
Breast cancer
■ Leading cause of death in women over the age of 50
■ Breast self examination important
■ Early detection
■ Improve detection
■ Genetic
■ Hormonal
■ Oral contraceptives
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Breast cancer: Risk factors
■ Age
■ Family history
■ Alcohol consumption
■ High fat diet
■ History of other cancers
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Breast cancer:
Assessment and common findings
■ WARING SIGNS:
   – Next page
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Breast cancer:
Assessment and common findings
■ WARING SIGNS:
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Breast cancer:
Management
■ Depending on stage
■ Even though chemotherapy is recommended for systemic treatment, surgical
  management is the most widely used management.
■ Chemotherapy is administered to eradicate the spread of disease
■ Radiation can also affect healthy cells, however, normal cells can repair themselves,
  while cancer cells cannot. Radiation therapy differs from chemotherapy — it is used
  to treat just the tumor, so it affects only the part of the body that has cancer.
     2018/10/02    Compiled by C Settley                                                  43
Breast cancer:
Surgical Management
■ Lumpectomy
   – Lumpectomy is surgery to
      remove cancer or other
      abnormal tissue from your
      breast. Lumpectomy is also
      called breast-conserving
      surgery.
■ Mastectomy
   – A mastectomy is surgery to
      remove a breast. In the past, a
      radical mastectomy with
      complete removal of the breast
      was the standard treatment for
      breast cancer.
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Premastectomy nursing management
■ Provide patient information about:
   – The tumour, its location and size
   – The spread
   – Surgery, chemotherapy & radiotherapy
   – Methods to compensate for physical changes
   – Duration & frequency of treatment, side effects and their management
■ Introduce to the oncology team
■ Postoperative bodily exercises can be introduced
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     Post mastectomy nursing management
■ Evaluate intensity of pain, relief pain & assess
■ Ensure that inserted drain is working
   – Surgeries which require drains are those in which fluid is expected to collect
      during healing.
■ Elevate affected arm to prevent oedema
■ Comfortable position
■ Apply heat to promote comfort
■ Commence arm exercises early to facilitate circulation, prevent congestion and
  oedema and promote comfort and healing
     2018/10/02    Compiled by C Settley                                              46
Post mastectomy exercises
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Reconstructive breast surgery
■ Breast reconstruction surgery is the creation of a new breast shape, or mound,
  using surgery.
■ It may be done after removal of a whole breast (mastectomy) or part of the breast
  (breast-conserving surgery).
■ Reconstruction can be done at the same time as breast cancer surgery (immediate
  reconstruction), or months or years later (delayed reconstruction).
■ There are three general options for breast reconstruction. One method is to use a
  breast implant, the second is to use the patient’s own tissue and the third combines
  both an implant and tissue.
    2018/10/02    Compiled by C Settley                                                  48
Reference list
■ https://www.mayoclinic.org/diseases-conditions/endometriosis/symptoms-
  causes/syc-20354656
■ https://www.menstrupedia.com/articles/physiology/cycle-phases
■ https://za.pinterest.com/pin/297659856614599891/
■ https://bestdoctors.com/blog/2017/10/06/staying-step-ahead-osteoporosis/
■ http://www.inboundwriter.com/health/what-is-breast-cancer-lumpectomy-2/
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