Advanced Cardiac Life Support
EMERGENCY CARDIAC CARE
                     Assess Responsiveness
              Unresponsive
              Call for code team and Defibrillator
              Assess breathing (open the airway, look,
              listen and feel for breathing)
                      If Not Breathing,
                      give two slow breaths.
                      Assess Circulation
    PULSE                                                  NO PULSE
                                                   Initiate CPR
 Give oxygen by bag mask
 Secure IV access                             If witnessed arrest, give
 Determine probable etiology of arrest        precordial thump and
 based on history, physical exam, cardiac     check pulse. If absent,
 monitor, vital signs, and 12 lead ECG.       continue CPR
                                               Ventricular
                                               fibrillation/tachycardia
                                                  (VT/VF) present on
    Hypotension/shock,                            monitor?
      acute pulmonary
      edema.
    Go to fig 8                          NO                         YES
                                Intubate                      VT/VF
                                Confirm tube placement        Go to Fig 2
                                Determine rhythm and
     Arrhythmia                    cause.
Bradycardia       Tachycardia            Electrical Activity?
Go to Fig 5       Go to Fig 6
                             YES                             NO
                   Pulseless electrical activity      Asystole
                   Go to Fig 3                        Go to Fig 4
     Fig 1 - Algorithm for Adult Emergency Cardiac Care
                  VENTRICULAR FIBRILLATION AND PULSELESS
                         VENTRICULAR TACHYCARDIA
    Assess Airway, Breathing, Circulation, Differential Diagnosis
    Administer CPR until defibrillator is ready (precordial thump if witnessed arrest)
    Ventricular Fibrillation or Tachycardia present on defibrillator
        Defibrillate immediately, up to 3 times at 200 J, 200-300 J, 360 J.
        Do not delay defibrillation
                                  Check pulse and Rhythm
Persistent or                         Continue CPR
recurrent VF/VT                       Secure IV access
                                      Intubate if no response
Continue CPR              Return of        Pulseless Electrical    Asystole
                          spontaneous      Activity                Go to Fig 4
                          circulation      Go to Fig 3
Epinephrine 1 mg
  IV push, repeat
  q3-5min or 2 mg in              Monitor vital signs
  10 ml NS via ET tube            Support airway
  q3-5min or                      Support breathing
Vasopressin 40 U IVP x            Provide medications appropriate for blood
  1 dose only                       pressure, heart rate, and rhythm
Defibrillate 360 J
Amiodarone (Cordarone) 300 mg IVP or
Lidocaine 1.5 mg/kg IVP, and repeat q3-5 min, up to total max of 3 mg/kg or
Magnesium sulfate (if Torsade de pointes or hypomagnesemic) 2 gms IVP or
Procainamide (if above are ineffective) 30 mg/min IV infusion to max 17 mg/kg
Continue CPR
Defibrillate 360 J, 30-60 seconds after each dose of medication
Repeat amiodarone (Cordarone) 150 mg IVP prn (if reurrent VF/VT) ,up to max
cumulative dose of 2200 mg in 24 hours
Continue CPR. Administer sodium bicarbonate 1 mEq/kg IVP if long arrest period
Repeat pattern of drug-shock, drug-shock
Note: Epinephrine, lidocaine, atropine may be given via endotracheal tube at
  2-2.5 times the IV dose. Dilute in 10 cc of saline.
After each intravenous dose, give 20-30 mL bolus of IV fluid and elevate
extremity.
Fig 2 - Ventricular Fibrillation and Pulseless Ventricular Tachycardia
              PULSELESS ELECTRICAL ACTIVITY
     Pulseless Electrical Activity Includes:
           Electromechanical dissociation (EMD)
           Pseudo-EMD
           Idioventricular rhythms
           Ventricular escape rhythms
           Bradyasystolic rhythms
           Postdefibrillation idioventricular rhythms
 Initiate CPR, secure IV access, intubate, assess pulse.
Determine differential diagnosis and treat underlying cause:
 Hypoxia (ventilate)
 Hypovolemia (infuse volume)
 Pericardial tamponade (perform pericardiocentesis)
 Tension pneumothorax (perform needle decompression)
 Pulmonary embolism (thrombectomy, thrombolytics)
 Drug overdose with tricyclics, digoxin, beta, or calcium blockers
 Hyperkalemia or hypokalemia
 Acidosis (give bicarbonate)
 Myocardial infarction (thrombolytics)
 Hypothemia (active rewarming)
     Epinephrine 1.0 mg IV bolus q3-5 min, or high dose
       epinephrine 0.1 mg/kg IV push q3-5 min; may give via
       ET tube.
     Continue CPR
   If bradycardia (<60 beats/min), give atroprine 1 mg IV, q3-5
      min, up to total of 0.04 mg/kg
   Consider bicarbonate, 1 mEq/kg IV (1-2 amp, 44 mEq/amp),
      if hyperkalemia or other indications.
 Fig 3 - Pulseless Electrical Activity
                        ASYSTOLE
        Continue CPR. Confirm asystole by
        repositioning paddles or by checking 2 leads.
        Intubate and secure IV access.
       Consider underlying cause, such as hypoxia,
       hyperkalemia, hypokalemia, acidosis, drug
       overdose, hypothermia. myocardial infarction.
       Consider transcutaneous pacing (TCP)
   Epinephrine 1.0 mg IV push, repeat every 3-5 min;
     may give by ET tube; high dose epinephrine 0.1
     mg/kg IV push q5min (1:1000 sln).
     Atropine 1 mg IV, repeat q3-5min up to a total of
       0.04 mg/kg; may give via ET tube.
      Consider bicarbonate 1 mEq/kg (1-2 amp) if
       hyperkalemia, acidosis, tricyclic overdose.
      Consider termination of efforts.
Fig 4 - Asystole
                                  BRADYCARDIA
 Assess Airway, Breathing, Circulation,    Assess vital signs
 Differential Diagnosis                    Review history
 Secure airway and give oxygen             Perform brief physical exam
 Secure IV access                          Order 12-lead ECG
 Attach monitor, pulse oximeter and
   automatic sphygmomanometer
            Too slow (<60 beats/min)
                           Bradycardia (<60 beats/min)
                        Serious Signs or Symptoms?
     No                                                            Yes
Type II second degree AV heart       If type II second or 3rd degree heart block,
block or third degree AV heart           wide complex escape beats, MI/ischemia,
block?                                   denervated heart (transplant),new bundle
                                         branch block: Initiate Pacing(transcutanous
                                         or venous)
                                     If type I second degree heart block, give
                                         atropine 0.5-1.0 mg IV, repeat q5min, then
                                         initiate pacing if bradycardia.
                                     Dopamine 5-20 mcg/kg per min IV infusion
                                     Epinephrine 2-10 mcg/min IV infusion
                                     Isoproterenol 2-10 mcg/min IV infusion
No                          Yes
Observe            Consider transcutaneous pacing or transvenous
                   pacing.
Fig 5 - Bradycardia (with patient not in cardiac arrest).
Assess Airway, Breathing, Circulation, Differential Diagnosis                     TACHYCARDIA
Assess Vitals, Secure Airway
Review history and examine patient.
Give 100% oxygen, secure IV access.
Attach ECG monitor, pulse oximeter, blood pressure monitor.
Order 12-lead ECG, portable chest x-ray.                                        IMMEDIATE CARDIOVERSION
                                                                                Atrial flutter 50 J, paroxysmal supraventricular tachycardia
                                                                                   50 J, atrial fibrillation 100 J, monomorphic ventricular
UNSTABLE, with serious signs or symptoms?
                                                                            Yes    tachycardia100 J, polymorphic V tach 200 J.
Unstable includes, hypotension, heart failure, chest pain, myocardial
                                                                                Premedicate with midazolam (Versed) 2-5 mg IVP when
  infarction, decreased mental status, dyspnea
                                                                                   possible.
             No or borderline
                     Atrial fibrillation                 Paroxysmal             Wide-complex                                    Torsade de pointes
                                                         supraventricular       tachycardia of           Ventricular            (polymorphic VT)
                     Atrial flutter                      narrow complex                                  tachycardia (VT)       with pulse present
                                                                                uncertain type           with pulse
                                                         tachycardia
                                                         (PSVT)                                          present
        Determine Etiology: Hypoxia, ischemia,
          MI, pulmonary embolus,                                               If uncertain if V tach,                          Correct underlying
          hyperthyroidism, electrolyte abnomality,                             give Adenosine 6
          theophylline, inotropes.                       Vagal maneuvers:      mg rapid IV push                                  cause: Hypokal-
                                                         Carotid sinus         over 1-3 sec                                      emia, drug over-
                                                           massage if no                                                         dose (tricyclic,
                                                           bruits
                                                                                           1-2 min                               phenothiazine,
 Control Rate: Diltiazem,verapamil, digoxin                                                                                      antiarrhythmic
 esmolol, metoprolol                                                            Adenosine                Amiodarone 150-         class Ia, Ic, III)
                                                                                  12 mg, rapid IV        300 mg IV over 10-
                                                                                  push over 1-3 sec      20 min
                                                         Adenosine                (may repeat once
 Cardioversion of atrial fibrillation to sinus rhythm:     6 mg, rapid IV          in 1-2 min)
 If less than 2 days and rate controlled:                  push over 1-3 sec
     Procainamide or amiodarone, followed by
     cardioversion
 If more than 2 days: Coumadin for 3 weeks;                       1-2 min
     control rate, start antiarrythmic agent, then
     electrical cardioversion.
Fig 6 Tachycardia
                                         Adenosine 12 mg, rapid IV           Lidocaine
                                          push over 1-3 seconds (may           1-1.5 mg/kg IV push.                       Magnesium 2-4 gm IV
                                          repeat once in 1-2 min); max         Repeat                                      over 5-10 min
                                          total 30 mg                          mg/kg IVP q5-10min
                                                                               to max total 3 mg/kg
                                                   Complex                                                             Overdrive
                                                                                                                         (cutaneous or venous)
                                                                                                                       Isoproterenol 2-20 mcg/min
                      Narrow                                          Wide                                               OR
                                                                                                                       Phenytoin 15 mg/kg IV at 50
                           Blood Pressure ?      If                                                                      mg/min OR
                                                 syndrome,                                                             Lidocaine 1.0-1.5 mg/kg IVP
                                                 (Cordarone) 150-300 mg IV                                             Cardioversion 200 J
Normal or elevated pressure      Low-unstable    over 10-20 min
                                                                                                  Procainamide
      Verapamil                                                                                     mg/min IV to max
        2.5-5 mg IV                           Procainamide                                          total 17 mg/kg
                                                 20-30 mg/min, max total 17 mg/kg;
               15-30 min                         followed by 2-4 mg/min
                                              If WPW, avoid adenosine, beta-
      Verapamil                                  blockers,
        5-10 mg IV                               digoxin
     Consider                      Synchronized cardioversion 100 J                            Lidocaine 1.0-1.5 mg/kg IVP
      Digoxin
      Beta
      Diltiazem
      Overdrive
      pacing                             Fig 6 - Tachycardia
                        STABLE TACHYCARDIA
               Stable tachycardia with serious signs and
               symptoms related to the tachycardia. Patient
               not in cardiac arrest.
If ventricular rate is >150 beats/min, prepare for immediate cardioversion.
Treatment of Stable Patients is based on Arrhythmia Type :
   Ventricular Tachycardia:
     Procainamide (Pronestyl) 30 mg/min IV, up to a total max of 17 mg/kg,
     or
     Amiodarone (Cordarone) 150-300 mg IV over 10-20 min, or
     Lidocaine 0.75 mg/kg. Procainamide should be avoided if ejection
     fraction is <40%.
   Paroxysmal Supraventricular Tachycardia: Carotid sinus pressure (if
     bruits absent), then adenosine 6 mg rapid IVP, followed by 12 mg rapid
     IVP x 2 doses to max total 30 mg. If no response, verapamil 2.5-5.0 mg
     IVP; may repeat dose with 5-10 mg IVP if adequate blood pressure; or
     Esmolol 500 mcg/kg IV over 1 min, then 50 mcg/kg/min IV infusion, and
     titrate up to 200 mcg/kg/min IV infusion.
   Atrial Fibrillation/Flutter:
     Ejection fraction $40%: Diltiazem (Cardiazem) 0.25 mg/kg IV over 2
     min; may repeat 0.35 mg/kg IV over 2 min prn x 1 to control rate. Then
     give procainamide (Pronestyl) 30 mg/min IV infusion, up to a total max
     of 17 mg/kg
     Ejection fraction <40%: Digoxin 0.5 mg IVP, then 0.25 mg IVP q4h x 2
     to control rate. Then give amiodarone (Cordarone) 150-300 mg IV over
     10-20 min.
                  Check oxygen saturation, suction device,
                  intubation equipment. Secure IV access
          Premedicate whenever possible with Midazolam (Versed)
          2-5 mg IVP or sodium pentothal 2 mg/kg rapid IVP
                         Synchronized cardioversion
                           Atrial flutter        50 J
                           PSVT                  50 J
                           Atrial fibrillation   100 J
                           Monomorphic V-tach 100 J
                           Polymorphic V tach 200 J
Fig 7 - Stable Tachycardia (not in cardiac arrest)
                                   HYPOTENSION, SHOCK, AND ACUTE PULMONARY EDEMA
                           Signs and symptoms of congestive heart failure, acute pulmonary edema.
                           Assess ABCD's, secure airway, administer oxygen; secure IV access. Monitor ECG, pulse oximeter,
                             blood pressure, order 12-lead ECG, portable chest X-ray
                           Check vital signs, review history, and examine patient. Determine differential diagnosis.
                                               Determine underlying cause
                                                      Pump Failure                                 Bradycardia or Tachycardia
   Hypovolemia
                                                                                                  Bradycardia Tachycardia
                                                 Determine blood pressure                         Go to Fig 5 Go to Fig 6
Administer Fluids, Blood
Consider vasopressors
Apply hemostasis; treat                                           Systolic BP >100 mm Hg
  underlying problem       Systolic BP         Systolic BP                                      Diastolic BP >110 mm Hg
                           <70 mm Hg           70-100 mm Hg       and diastolic BP normal
          Norepinephrine 0.5-                                         Dobutamine2.0-20
                                     Dopamine 2.5-20                  mcg/kg per min IV            If ischemia and hypertension:
           30 mcg/min IV or           mcg/kg per min IV                                            Nitroglycerin10-20
          Dopamine 5-20               (add norepinephrine                                          IV, and titrate to effect and/or
           mcg/kg per min             if dopamine is >20        Furosemide IV 0.5-1.0 mg/kg        Nitroprusside 0.1-5.0
                                      mcg/kg per min)           Morphine IV 1-3 mg                 mcg/kg/min IV
                                                                Nitroglycerin SL 0.4 mg tab
                                                                  q3-5min x3
                                                                Oxygen
     Fig 8 - Hypotension, Shock, and Acute Pulmonary Edema