Date Name Discovery
Blood was given to him from 3 young men, all
1492 Pope Innocent VII four died.
First time a blood transfusion was recorded.
First blood preservation research
1869 Braxton Hicks
Sodium phosphate as an anticoagulant
ABO blood groups
1901 Karl Landsteiner
Noble prize winner in the 20th century
Vein-to-vein transfusion by multiple syringes
Edward E. Lindemann
and a special cannula
Unger Syringe-valve apparatus
Sodium citrate as an anticoagulant solution for
1914 Hustin
transfusion
Determined the minimum amount of citrate
1915 Lewisohn needed for anticoagulation and demonstrated
its nontoxicity in small amounts
Glucose was tried as a preservative for blood
1916 Rous and Turner
in the form of citrate-dextrose
Function of glucose in the RBC metabolism
1930s
was understood
Developed techniques in blood preservation
WW-II and blood transfusion that led to the
Dr. Charles Drew widespread system of blood banks
Appointed the director of the 1st American Red
Feb 1941
Cross blood bank at Presbyterian Hospital
Introduced the formula for the preservative
1943 Loutit and Mollison
acid-citrate-dextrose (ACD)
Devoted nearly dozen papers to blood
Journal of Clinical preservation
Jul 1947
Investigation Blood banks in US; transfusion became
commonplace
Introduced an improved preservative called
1957 Gibson
citrate-phosphate-dextrose; less acidic