DRUG STUDY
Name Mechanism of Indications Contraindications Adverse Effects Nursing
Action Interventions
Generic Name: Increases metabolic For treating Thyrotoxicosis, Side effects: Instruct patient to take the
methimazole rate, cardiac output Hyperthyroidism myocardial infarction Nausea and vomiting, drug with meals to decrease
and protein and severe renal diarrhea, cramps, tremors, gastrointestinal symptoms
Brand Name: synthesis. Useful for disease nervousness, insomnia,
Tapazole treating thyrotoxic headache and weight loss Advise patient about the
crisis and in effects of iodine and its
Dose: 10 mg preparation for Adverse Effects: presence in iodized salt,
subtotal Tachycardia, hypertension shellfish and OTC cough
Route: PO thyroidectomy. and palpitations medicines
Frequency: TID
Emphasize the importance of
Classification: anti- drug compliance; abruptly
thyroid agent stopping the antithyroid drug
could bring on a thyroid crisis
Teach patient the signs and
symptoms of hypothyroidism:
lethargy, puffy eyelids and
face, thick tongue, slow
speech with hoarseness, lack
of perspiration and slow
pulse. Hypothyroidism may
result to treatment of
Hyperthyroidism
Name Mechanism of Indications Contraindications Adverse Effects Nursing
Action Interventions
Generic Name: Calcium Gluconate Negative calcium Ventricular fibrillation, Body as a Whole: Assess for cutaneous burning
Calcium Gluconate acts like digitalis on balance (As in metastatic bone tingling sensation. With sensations and peripheral
the heart, increasing neonatal tetany, disease, injection into rapid IV, sensations of vasodilation, with moderate
Classification: cardiac muscle tone hypoparathyroidism, myocardium; renal heat waves (peripheral fall in BP, during direct IV
Electrolyte and and force of vitamin D calculi, hypercalcemia, vasodilation), fainting. injection.
Water Balance systolic deficiency, predisposition to GI: PO preparation: Monitor ECG during IV
contractions alkalosis). Also to hypercalcemia constipation, increased administration to detect
(positive inotropic overcome cardiac (hyperparathyroidism, gastric acid secretion. evidence of hypercalcemia:
effect) toxicity of certain malignancies); CV: (with rapid infusion) decreased QT interval
hyperkalemia, for digitalis toxicity. hypotension, bradycardia, associated with inverted T-
Rapidly and cardiopulmonary cardiac arrhythmias, wave.
effectively restores resuscitation, to cardiac arrest. Lab tests: determine levels of
serum calcium prevent Skin: pain and burning at calcium and phosphorus and
levels in acute hypocalcemia IV site, severe Vegas magnesium frequently, during
hypocalcemia of during transfusion thrombosis, necrosis and sustained therapy.
various origins; of citrated blood. sloughing (with Deficiencies and other ions,
also effective as a Also as antidote for extravasation). particularly magnesium,
cardiac stabilizer magnesium sulfate, frequently coexist with
under conditions of for acute symptoms calcium ion depletion
hyperkalemia or of lead colic, to
resuscitation. decrease capillary
permeability in
sensitivity reactions,
and to relieve
muscle cramps from
insect bites or
stings. Oral calcium
may be used to
maintain normal
calcium balance
during pregnancy,
lactation, and
childhood growth
and to prevent
primary
osteoporosis. Also
an osteoporosis,
osteomalacia,
chronic
hypoparathyroidism,
rickets, and as
adjunct in treatment
of myasthenia
gravis and Eaton-
Lambert syndrome.
Yes, as prescribed I will give the medications to the patient. As for the patient was diagnosed with hyperthyroidism, Methimazole prevents the thyroid gland from
producing too much thyroid hormone. It is also used before thyroid surgery and it also helps to achieve a euthyroid state via long-term management or until another
treatment (radioiodine ablation or surgery) may be pursued. In addition, the prophylactic intravenous injection of calcium gluconate during total thyroidectomy is
effective in minimizing risk for postoperative symptomatic hypocalcaemia.
