Calculations IV
Question 1
Georgia is a 71 year old female admitted to the hospital with bowel obstruction. She will be NPO
for at least the next several days and will be starting PN therapy. Georgia weighs 57 kg and is
5'2". Calculate her estimated fluid requirements using the formula 1500 mL + 20 mL(wt in kg -
20). (Answer must be numeric; no units or commas.)
Question 2
The pharmacist needs to add an additional 400 calories to a PN. If the pharmacist is using a 10%
lipid emulsion, how many milliliters are required to meet the remaining calories? (Answer must
be numeric; no units or commas; round final answer to the nearest WHOLE number.)
Question 3
Express 0.00088% w/v as parts per million (PPM):
Answer
A 888 PPM
B 88.8 PPM
C 8.8 PPM
D 0.88 PPM
E 0.088 PPM
Question 4
How many grams of triamcinolone should be used in preparing the following prescription?
Rx: Triamcinolone (w/v) 5% Glycerin qs ad 10 mL Sig. One drop in each ear
(Answer must be numeric; no units or commas; include a leading zero when answer is less than 1.)
Question 5
Express 0.02% as a ratio strength. (Answer must be numeric; no units or commas; do not enter
the 1 and the colon; enter only the number after the colon, as shown here with Xs: 1:XXX.)
Question 6
Which of the following statements accurately describes the pH scale?
Answer
A A lower pH correlates with a higher concentration of hydrogen ions in solution.
B A higher pH correlates with a higher concentration of hydrogen ions in solution.
C Solutions with a pH less than 7 are said to be basic.
D Solutions with a pH greater than 8 are said to be acidic.
E It measures the tonicity of a solution.
Question 7
The pharmacist receives a prescription for "Percocet 5/325 mg tab #24, Sig; i-ii tabs po q 4-6 hrs
prn pain x 2 days. NTE 10/d." Choose the correct wording for the prescription label.
Answer
A Take 1-2 tablets by mouth every 4-6 hours as desired for pain. Do not exceed 10 tablets per day.
B Take 1-2 tablets by mouth every 4-6 hours as-needed for pain for 2 days. Do not exceed 10 tablets per
day.
C Take up to 2 tablets by mouth every 4 hours as-needed for pain. Do not exceed 10 tablets per day.
D Take 1-2 tablets by mouth every 4-6 hours as-needed for pain. Do not exceed 6 tablets per day.
E Take 1-2 tablets by mouth up to 6 times daily as-needed for pain for 2 days. Do not exceed 12 tablets
per day.
Question 8
A patient needs 110 grams of protein/day. If the pharmacy stocks Aminosyn 10%, how many
milliliters of fluid will be supplied by the protein component? (Answer must be numeric; no
units or commas; round final answer to the nearest WHOLE number.)
Question 9
How many grains of aspirin will be contained in each capsule?
Rx: Aspirin 15 g Diphenhydramine 1.2 g Lactose 1 g No. 30 caps Sig. One capsule QHS prn
sleep.
(Answer must be numeric; no units or commas; round the final answer to the nearest TENTH.)
Question 10
Express 0.005% in parts per million (PPM). (Answer must be numeric; no units or commas;
include a leading zero when answer is less than 1.)
Question 11
A patient is receiving 650 mL of 10% lipids on Tuesdays and Thursdays. How many calories is
the patient receiving from the lipids each week? (Answer must be numeric; no units or
commas.)
Question 12
If a codeine suspension contains 15 mg of codeine per 5 mL, how many grams of codeine would
be used in preparing 240 mL of the suspension? (Answer must be numeric; no units or commas;
include a leading zero when answer is less than 1.)
Question 13
What is the ratio strength of 100 mL containing a 1:50 povidone iodine solution diluted to 1000
mL? (Answer must be numeric; no units or commas; do not enter the 1 and the colon; enter only
the number after the colon, as shown here with Xs: 1:XXX.)
Question 14
Which of the following is the principal extracellular cation?
Answer
A Sodium
B Magnesium
C Calcium
D Potassium
E Manganese
Question 15
The Cockcroft-Gault equation may not provide a reliable estimate of actual renal clearance in all
situations. Some circumstances when an alternate method or formula may be preferable include:
(Select ALL that apply.)
Answer
A When renal function is fluctuating rapidly
B In end stage renal disease
C In very young children
D In young, healthy adults
E In patients with mild-moderate renal insufficiency
Question 16
A pharmacist mixes 200 mL of 20% dextrose with 100 mL of 5% dextrose. What is the final
dextrose concentration (%w/v)? (Answer must be numeric; no units or commas.)
Question 17
A patient weights 278 pounds. What is the formula to convert the patients weight into kilograms?
Answer
A Multiply the pounds by 2.2
B Divide the pounds by 3.5
C Multiply the pounds by 2.54
D Divide the pounds by 2.2
E Multiply the pounds by 0.75
Question 18
How many mL of a 1:5000 (w/v) solution of aluminum acetate can be made from 100 mL of a
0.3% solution? (Answer must be numeric; no units or commas; round the final answer to the
nearest WHOLE number.)
Question 19
Tim requires 1.5 g/kg/day of protein (based on his actual body weight) which will be provided
by Aminosyn 15%. Tim is a 62 year old male (weight 89 kg, height 6'2") who is confined to bed
(activity factor 1.2) due to his current pneumonia infection (stress factor 1.6). How many
milliliters of Aminosyn 15% should he receive. (Answer must be numeric; no units or commas;
round final answer to the nearest WHOLE number.)
Question 20
The clinical pharmacist in the Pediatric ICU is asked to determine what rate to run a child's IV at.
The IV contains 9 mL of 39.2 % potassium acetate in normal saline to prepare a 1 L bag. The
prescriber wants the child to receive 2.5 mEq/hr. (MW of K = 39; MW of acetate = 59). What
rate (in mL/hr) would provide the desired mEq/hr of potassium acetate? (Answer must be
numeric; no units or commas; round the final answer to the nearest WHOLE number.)
Question 21
How many grams of 2.5% hydrocortisone cream should be mixed with 56 grams of 0.25%
hydrocortisone cream to prepare a 1% cream? (Answer must be numeric; no units or commas.)
Question 22
A 30 mL nasal spray delivers 18 sprays per mL of solution. Each spray contains 1.25 mg of
active drug. How many milligrams of drug are contained in the 30 mL package? (Answer must
be numeric; no units or commas.)
Question 23
What is the specific gravity (SG) of 75 mL of clove oil weighing 78 grams? (Answer must be
numeric; no units or commas; include a leading zero when answer is less than 1.)
Question 24
Peter is a 46 year old male (274 pounds, 6'3") who has been admitted for bowel resection
surgery. Post surgery, he is to be started on PN therapy. The physician wants the patient to
receive 1.2 g/kg/day of protein. Calculate his daily protein requirement in grams using his actual
body weight. (Answer must be numeric; no units or commas; round final answer to the
nearest WHOLE number.)
Question 25
Using a 10% lipid emulsion, how many milliliters (mL) are required to meet 680
calories? (Answer must be numeric; no units or commas; round final answer to the nearest
WHOLE number.)
Question 26
Express 450 parts per million (PPM) as a percentage. (Answer must be numeric; no units or
commas; include a leading zero when answer is less than 1.)
Question 27
The pharmacy receives the following PN order. How many milliliters of sodium chloride 23.4%
(4 mEq/mL) should be added to the PN. (Answer must be numeric; no units or commas.)
Item/Quantities:
Dextrose 270 g
Amino acids 60 g
Sodium chloride 38 mEq
Sodium acetate 16 mEq
Potassium 40 mEq
Magnesium sulfate 10 mEq
Phosphate 21 mmol
Calcium 4.45 mEq
MVI-12 5 mL
Trace elements 1 mL
Vitamin K-1 0.5 mg
Famotidine 10 mg
Regular insulin 40 units
Sterile water qs ad 980 mL
Question 28
An albuterol metered dose inhaler (MDI) provides 90 mcg of medication in each inhalation. If
the total weight of the medication in the canister is 18 mg, how many inhalations will be required
to deplete the MDI? (Answer must be numeric; no units or commas; round the final answer to
the nearest WHOLE number.)
Question 29
One pint of rifampin oral suspension contains 4,730 milligrams of rifampin. How many grams of rifampin
are contained in 120 milliliters of the suspension? (Answer must be numeric; no units or commas; round
the final answer to the nearest TENTH.)
Question 30
The intravenous dose of digoxin is 80% of the oral digoxin dose. If the oral dose is 20 mcg/kg,
what is the intravenous dose, in micrograms, for a 6 year old child weighing 50 lbs? (Answer
must be numeric; no units or commas; round the final answer to the nearest WHOLE number.)
Question 31
How many milliliters of capsaicin liquid (50 mg/mL) will be needed to prepare 42.5 grams of a
0.15% cream (w/w)? (Answer must be numeric; no units or commas; include a leading zero
when answer is less than 1; round the final answer to the nearest TENTH.)
Question 32
Express 1:1500 as a percentage strength. (Answer must be numeric; no units or commas; include
a leading zero if answer is less than 1; round the final answer to the nearest THOUSANDTH.)
Question 33
Phosphoric acid has a specific gravity (SG) of 1.70. How many quarts of phosphoric acid would
be needed to compound a prescription that requires 3216 grams of phosphoric acid? (Answer
must be numeric; no units or commas; round the final answer to the nearest WHOLE number.)
Question 34
A patient will receive 114 grams of protein in the PN bag. How many calories are provided by
the protein component? (Answer must be numeric; no units or commas; round final answer to the
nearest WHOLE number.)
Question 35
A female comes to the pharmacy. She is 5'2" tall and 156 pounds. Select the correct BMI for this
patient and the corresponding classification:
Answer
A 23, obese
B 29, overweight
C 23, normal
D 23, overweight
E 29, obese
Question 36
How many kcals are provided by 91 grams of protein? (Answer must be numeric; no units or
commas; round final answer to the nearest WHOLE number.)
Question 37
How many milliliters (mL) of guaifenesin syrup are contained in each dose of the prescription
below? (Answer must be numeric; no units or commas; round the final answer to the
nearest WHOLE number.)
Rx:
Phenergan syrup 60 mL
Guaifenesin syrup qs ad 200 mL
Sig. ii tsp PRN cough
Question 38
Measure out 60 g of a 40% ephedrine sulfate using the 60% and 20% in stock. How much of the
60% and the 20% (in grams) are needed?
Answer
A 40 g of 60%, 20 g of 20%
B 35 g of 60%, 25 g of 20%
C 50 g of 60%, 10 g of 20%
D 20 g of 60%, 40 g of 20%
E 30 g of 60%, 30 g of 20%
Question 39
A patient is receiving 275 mL of 20% lipids. How many calories is the patient receiving from the
lipids? (Answer must be numeric; no units or commas; round final answer to the
nearest WHOLE number.)
Question 40
How many milliliters of aminophylline injection containing 250 mg aminophylline in each 10
mL should be used in filling a medication order calling for 10 mg of aminophylline? (Answer
must be numeric; no units or commas; include a leading zero when answer is less than 1.)
Answers:
1) 2240
2) 364
3) C
4) 0.5
5) 5000
6) A
7) B
8) 1100
9) 7.7
10) 50
11) 1430
12) 0.72
13) 500
14) A
15) A, B, C
16) 15
17) D
18) 1500
19) 890
20) 69
21) 28
22) 675
23) 1.04
24) 149
25) 618
26) 0.045
27) 9.5
28) 200
29) 1.2
30) 364
31) 1.3
32) 0.067
33) 2
34) 456
35) B
36) 364
37) 7
38) E
39) 550
40) 0.4
