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Name: Gotoh, Aaron Tzergio C. DATE: 05/12/20 Erythrocyte Indices Worksheet

This document contains an erythrocyte indices worksheet that defines and provides the normal ranges for mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), and mean corpuscular hemoglobin concentration (MCHC). It then provides three examples to calculate these indices based on given RBC count, hemoglobin, and hematocrit values. The first example results in normal MCV, MCH, and MCHC, indicating a normocytic, normochromic state. The second example shows low MCV, MCH, indicating a microcytic, hypochromic state. The third example shows high MCV with low MCH and MCHC, indicating a macrocytic, hypochromic

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166 views3 pages

Name: Gotoh, Aaron Tzergio C. DATE: 05/12/20 Erythrocyte Indices Worksheet

This document contains an erythrocyte indices worksheet that defines and provides the normal ranges for mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), and mean corpuscular hemoglobin concentration (MCHC). It then provides three examples to calculate these indices based on given RBC count, hemoglobin, and hematocrit values. The first example results in normal MCV, MCH, and MCHC, indicating a normocytic, normochromic state. The second example shows low MCV, MCH, indicating a microcytic, hypochromic state. The third example shows high MCV with low MCH and MCHC, indicating a macrocytic, hypochromic

Uploaded by

Marie Llanes
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© © All Rights Reserved
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NAME: GOTOH,AARON TZERGIO C.

DATE: 05/12/20

ERYTHROCYTE INDICES WORKSHEET


✔ PURPOSE: Important in assessing borderline types of anemia
✔ Computed using 3 determination: RBC count, Hemoglobin and Hematocrit
Erythrocyte Definition Formula Normal Values Increased Decreased
Indices

CORPUSCULAR The mean MCV in fl = (Hct normal range for cyte, Hyperchromic ytic, Hypochromic
VOLUME corpuscular [in L/L]/RBC MCV is between oblastic anemia, ficiency anemia,
(MCV) volume, or mean [in x1012/L]) x 80 and 96 hemolytic anemia thalassemia,
cell volume, is a 1000. femtoliters per with reticulocytes, sideroblastic
measure of the cell. liver disease and anemia, lead
average volume normal in poisoning
of a red blood newborns
corpuscle. The
measure is
attained by
multiplying a
volume of blood
by the
proportion of
blood that is
cellular, and
dividing that
product by the
number of
erythrocytes in
that volume.

CORPUSCULAR mean Hb(g/dL)*10/ NORMAL VALUE: cyte, Hyperchromic ytic, Hypochromic


HEMOGLOBIN corpuscular RBC(10^12/L)
27-33pg
(MCH) hemoglobin , or
"mean cell
hemoglobin"
(MCH), is the
average mass of
hemoglobin (Hb)
per red blood
cell (RBC) in a
sample of blood.
It is reported as
part of a
standard
complete blood
count. MCH
value is
diminished in
hypochromic
anemias.

CORPUSCULAR mean REFERENCE e error in RBC/ Hb chromic cells, Fe


HEMOGLOBIN corpuscular MCHC=Hgb(g/ RANGE: measurement, deficiency
CONCENTRATI hemoglobin dL)/Hct(L/L) 320-360g/L spherocytes anemia
ON (MCHC) concentration. (hyperchromic)
32-36%
It's a measure of
the average
concentration of
hemoglobin
inside a single
red blood cell.

In normochromic anemias: inc/dec MCV, inc/dec MCH (associated with the RBC, MCHC is NORMAL_
In hypochromic anemias: all indices are DECREASED

EXERCISE: SOLVE FOR THE 3 INDICES AND INTERPRET. In your interpretation: describe the size (Normocytic,
Microcytic and Macrocytic) and Hemoglobin concentration ( Normochromic, Hypochromic and Hyperchromic).
Enclose your final answers in a box.
1. RBC= 4.5x1012/L, Hb , Hb= 13.5g/dL, Hct=40%

● MCV=Hct(%)x10/RBC(10^12/L)

=(0.40)x1000/4.5x10^12/L

MCV=88.8fL

● MCH=Hb(g/dL)x10/RBC(10^12/L)

= 13.5g/dL/4.5x10^12/L x10

MCH= 30pg

● MCHC=Hb(g/dL)/Hct(%)

=24.5g/dL/(0.40)

MCHC=33.8g/dL

INTERPRETATION: NORMOCYTIC,NORMOCHROMIC

2. RBC= 4.5x1012/L, Hb , Hb= 10.0g/dL, Hct=32%


● MCV=Hct(%)x10/RBC(10^12/L)
=(0.32) x 1000/4.5x10^12/L
MCV= 71.1fL

● MCH=Hb(g/dL)x10/RBC(10^12/L)
=10.0g/dL/4.5x10^12/L x 10/4.5x10^12/L
MCH= 22.2pg

● MCHC= Hb(g/dL)/ Hct(L/L)


= 10.0g/dL/(0.32)
MCHC= 31.25g/dL

INTERPRETATION: MICROCYTIC, HYPOCHROMIC

3. RBC= 2.2x1012/L, Hb , Hb= 7.5g/dL, Hct=25%

● MCV= Hct(%) x10/RBC(10^12/L)

=(0.25)x1000/2.2x10^12/L

MCV= 113.6fL

● MCH=Hb(g/dL) x 10/RBC(10^12/L)

=7.5g/dL x10/2.2x10^12/L

MCH= 31.09 pg
● MCHC = Hb(g/dL)/Hct(L/L)

= 7.5g/dL/(0.25)

MCHC= 30g/dL

INTERPRETATION:MACROCYTIC,HYPOCHROMIC

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