SAFETY DATA SHEET Version 6.
3
Revision Date 27.09.2020
according to Regulation (EC) No. 1907/2006 Print Date 29.07.2021
GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifiers
Product name : 4-Bromo-1-butylboronic acid catechol ester
Product Number : 513687
Brand : Aldrich
REACH No. : A registration number is not available for this substance as the
substance or its uses are exempted from registration, the
annual tonnage does not require a registration or the
registration is envisaged for a later registration deadline.
CAS-No. : 142172-51-8
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances
1.3 Details of the supplier of the safety data sheet
Company : Sigma-Aldrich Chemie GmbH
Eschenstrasse 5
D-82024 TAUFKIRCHEN
Telephone : +49 (0)89 6513-1130
Fax : +49 (0)89 6513-1161
E-mail address : technischerservice@merckgroup.com
1.4 Emergency telephone
Emergency Phone # : 0800 181 7059 (CHEMTREC Deutschland)
+49 (0)696 43508409 (CHEMTREC
weltweit)
SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008
Skin corrosion (Category 1B), H314
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008
Pictogram
Signal word Danger
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Hazard statement(s)
H314 Causes severe skin burns and eye damage.
Precautionary statement(s)
P280 Wear protective gloves/ protective clothing/ eye protection/ face
protection.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes.
Remove contact lenses, if present and easy to do. Continue
rinsing.
P310 Immediately call a POISON CENTER/ doctor.
Supplemental Hazard none
Statements
2.3 Other hazards - none
SECTION 3: Composition/information on ingredients
3.1 Substances
Synonyms : 2-(4-Bromobutyl)-1,3,2-benzodioxaborole
Formula : C10H12BBrO2
Molecular weight : 254,92 g/mol
CAS-No. : 142172-51-8
Component Classification Concentration
4-Bromo-1-butylboronic acid catechol ester
Skin Corr. 1B; H314 <= 100 %
For the full text of the H-Statements mentioned in this Section, see Section 16.
SECTION 4: First aid measures
4.1 Description of first-aid measures
General advice
Consult a physician. Show this material safety data sheet to the doctor in attendance.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact
Take off contaminated clothing and shoes immediately. Wash off with soap and plenty of
water. Consult a physician.
In case of eye contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed
Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse
mouth with water. Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section
2.2) and/or in section 11
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4.3 Indication of any immediate medical attention and special treatment needed
No data available
SECTION 5: Firefighting measures
5.1 Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture
Carbon oxides, Hydrogen bromide gas, Borane/boron oxides
5.3 Advice for firefighters
Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information
No data available
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid dust formation. Avoid breathing vapors, mist or
gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust.
For personal protection see section 8.
6.2 Environmental precautions
Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up
Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in
suitable, closed containers for disposal.
6.4 Reference to other sections
For disposal see section 13.
SECTION 7: Handling and storage
7.1 Precautions for safe handling
Avoid formation of dust and aerosols.
Provide appropriate exhaust ventilation at places where dust is formed.Normal measures
for preventive fire protection.
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
Recommended storage temperature 2 - 8 °C
Handle and store under inert gas. Air and moisture sensitive.
7.3 Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
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SECTION 8: Exposure controls/personal protection
8.1 Control parameters
Ingredients with workplace control parameters
8.2 Exposure controls
Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands
before breaks and at the end of workday.
Personal protective equipment
Eye/face protection
Face shield and safety glasses Use equipment for eye protection tested and
approved under appropriate government standards such as NIOSH (US) or EN
166(EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact
with this product. Dispose of contaminated gloves after use in accordance with
applicable laws and good laboratory practices. Wash and dry hands.
The selected protective gloves have to satisfy the specifications of Regulation (EU)
2016/425 and the standard EN 374 derived from it.
Body Protection
Complete suit protecting against chemicals, The type of protective equipment must
be selected according to the concentration and amount of the dangerous substance
at the specific workplace.
Respiratory protection
Where risk assessment shows air-purifying respirators are appropriate use a full-
face particle respirator type N100 (US) or type P3 (EN 143) respirator cartridges as
a backup to engineering controls. If the respirator is the sole means of protection,
use a full-face supplied air respirator. Use respirators and components tested and
approved under appropriate government standards such as NIOSH (US) or CEN
(EU).
Control of environmental exposure
Do not let product enter drains.
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
a) Appearance Form: solid
b) Odor No data available
c) Odor Threshold No data available
d) pH No data available
e) Melting No data available
point/freezing point
f) Initial boiling point No data available
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and boiling range
g) Flash point 105 °C - closed cup
h) Evaporation rate No data available
i) Flammability (solid, No data available
gas)
j) Upper/lower No data available
flammability or
explosive limits
k) Vapor pressure No data available
l) Vapor density No data available
m) Relative density 1,372 g/cm3
n) Water solubility No data available
o) Partition coefficient: No data available
n-octanol/water
p) Autoignition No data available
temperature
q) Decomposition No data available
temperature
r) Viscosity No data available
s) Explosive properties No data available
t) Oxidizing properties No data available
9.2 Other safety information
No data available
SECTION 10: Stability and reactivity
10.1 Reactivity
No data available
10.2 Chemical stability
Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions
No data available
10.4 Conditions to avoid
Air Avoid moisture.
10.5 Incompatible materials
Strong oxidizing agents
10.6 Hazardous decomposition products
Hazardous decomposition products formed under fire conditions. - Carbon oxides, Hydrogen
bromide gas, Borane/boron oxides
Other decomposition products - No data available
In the event of fire: see section 5
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SECTION 11: Toxicological information
11.1 Information on toxicological effects
Acute toxicity
No data available
Skin corrosion/irritation
No data available
Serious eye damage/eye irritation
No data available
Respiratory or skin sensitization
No data available
Germ cell mutagenicity
No data available
Carcinogenicity
IARC: No ingredient of this product present at levels greater than or equal to 0.1% is
identified as probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
No data available
Specific target organ toxicity - single exposure
No data available
Specific target organ toxicity - repeated exposure
No data available
Aspiration hazard
No data available
Additional Information
RTECS: Not available
Cough, Shortness of breath, Headache, Nausea, Vomiting
SECTION 12: Ecological information
12.1 Toxicity
No data available
12.2 Persistence and degradability
No data available
12.3 Bioaccumulative potential
No data available
12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment
PBT/vPvB assessment not available as chemical safety assessment not required/not
conducted
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12.6 Other adverse effects
No data available
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a
licensed professional waste disposal service to dispose of this material. Dissolve or mix
the material with a combustible solvent and burn in a chemical incinerator equipped with
an afterburner and scrubber.
Contaminated packaging
Dispose of as unused product.
SECTION 14: Transport information
14.1 UN number
ADR/RID: 3261 IMDG: 3261 IATA: 3261
14.2 UN proper shipping name
ADR/RID: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S. (4-Bromo-1-butylboronic acid
catechol ester)
IMDG: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S. (4-Bromo-1-butylboronic acid
catechol ester)
IATA: Corrosive solid, acidic, organic, n.o.s. (4-Bromo-1-butylboronic acid catechol
ester)
14.3 Transport hazard class(es)
ADR/RID: 8 IMDG: 8 IATA: 8
14.4 Packaging group
ADR/RID: II IMDG: II IATA: II
14.5 Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user
No data available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the
substance or mixture
This material safety data sheet complies with the requirements of Regulation (EC) No.
1907/2006.
International Chemical Weapons Convention : Neither banned nor restricted
(CWC) Schedules of Toxic Chemicals and
Precursors
Restrictions on the marketing and use of certain : Neither banned nor restricted
dangerous substances
Regulation (EC) No 649/2012 of the European : Neither banned nor restricted
Parliament and the Council concerning the
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export and import of dangerous chemicals
Candidate List of Substances of Very High : Neither banned nor restricted
Concern for Authorisation
15.2 Chemical Safety Assessment
For this product a chemical safety assessment was not carried out
SECTION 16: Other information
Full text of H-Statements referred to under sections 2 and 3.
H314 Causes severe skin burns and eye damage.
Further information
Copyright 2020 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies
for internal use only.
The above information is believed to be correct but does not purport to be all inclusive
and shall be used only as a guide. The information in this document is based on the
present state of our knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any guarantee of the properties of
the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any
damage resulting from handling or from contact with the above product. See
www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional
terms and conditions of sale.
The branding on the header and/or footer of this document may temporarily not visually
match the product purchased as we transition our branding. However, all of the
information in the document regarding the product remains unchanged and matches the
product ordered. For further information please contact mlsbranding@sial.com.
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