DRUG STUDY
Date Generic Brand Classificatio Indication Mechanism Dosage & Time Adverse Nursing
Name Name n of Action Frequency Given Reaction Consideration
Dextrose dextros Glucose 50% Dextrose Hyperosmol Do not use
50% e elevating Dextrose restores intravenous ar unless the
Injection monohy agents Injection is blood injection of syndrome, solution is clear
drate indicated in glucose 10 to 25 resulting and seal is
the levels in grams of from intact. Discard
treatment of hypoglyce dextrose excessively unused portion.
insulin mia and (20 to 50 rapid Electrolyte
hypoglycem provides a mL of 50% administratio deficits,
ia source of dextrose) n of particularly in
(hyperinsuli carbohydra concentrated serum potassium
nemia or te calories dextrose and phosphate,
insulin after IV may cause may occur
shock) to injection. It mental during prolonged
restore decreases confusion use of
blood losses of and/or loss concentrated
glucose body of dextrose
levels. The protein and consciousne solutions.
solution is nitrogen, ss.
also promotes Reactions Blood electrolyte
indicated, glycogen which may monitoring is
after deposition, occur essential and
dilution, for and because of fluid and
intravenous prevents the solution electrolyte
infusion as ketosis. It or the imbalances
a source of reverses technique of should be
carbohydrat CNS administratio corrected.
e calories in effects of n include Essential
patients hypoglyce febrile vitamins and
whose oral mia by response, minerals also
intake is rapidly infection at should be
restricted or increasing the site of provided as
inadequate serum injection, needed.
to maintain glucose venous
nutritional levels. thrombosis To minimize
requirement Dextrose or phlebitis hyperglycemia
s. Slow injection extending and consequent
infusion of undergoes from the site glycosuria, it is
hypertonic oxidation to of injection, desirable to
solutions is carbon extravasatio monitor blood
essential to dioxide and n and and urine
insure water. hypervolemi glucose and if
proper Water is an a. If an necessary, add
utilization of essential adverse insulin. When a
dextrose constituent reaction concentrated
and avoid of all body does occur, dextrose infusio
production tissues discontinue is abruptly
of Average the infusion, withdrawn, it is
hyperglyce normal evaluate the advisable to
mia. adult patient, follow with the
requiremen institute administration o
t ranges appropriate 5% or 10%
from two to therapeutic dextrose
three liters. countermeas injection to avoid
Water ures and rebound
balance is save the hypoglycemia.
maintained remainder of
by various the fluid for Solutions
regulatory examination containing
mechanism if deemed dextrose should
s. Water necessary. be used with
distribution caution in
depends patients with
primarily on known
the subclinical or
concentrati overt diabetes
on of mellitus.
electrolytes
in the body Care should be
compartme exercised to
nts. insure that the
needle is well
within the lumen
of the vein and
that
extravasation
does not occur.
If thrombosis
should occur
during
administration,
the injection
should be
stopped and
corrective
measures
instituted.
Concentrated
dextrose
solutions should
not be
administered
subcutaneously
or
intramuscularly.
