DOMADOL
50 mg capsules
Tramadol hydrochloride                                                  50 mg/1 ml and 100 mg/2 ml injections
                                                                                        For the management of moderate
                                                                                            to moderately severe pain
The dosage should be adjusted to the intensity of pain and the individual’s response to the
analgesic action of DOMADOL. DOMADOL should not be used for the treatment of minor pain.
Via oral dosage                                                                                Post-operative pain
                                                                                               •	 Initial bolus of 100 mg.
Adults and children over the age of 14
years:                                                                                         •	 During the 90 minutes following initial bolus, further 	
•	 Initial dose of 50 mg followed by 100 mg twice daily.                                       	 doses of 50 mg may be given every 30 minutes, up to 	
                                                                                               	 a total dose of 250 mg including the initial bolus.
•	 The dose may be increased to 150 mg or 200 mg 	
	 twice daily.                                                                                 •	 Subsequent doses should be 50 mg or 100 mg 4 to 6 	
                                                                                               	 hourly up to a total daily dose of 600 mg.
•	 A total daily dose of 400 mg may not be exceeded.
                                                                                               •	 For less severe pain 50 mg or 100 mg 4 to 6 hourly.
Post - operative pain:                                                                         *Dosage adjustment may be required for patients
•	 50 mg to 100 mg 4 to 6 hourly up to a total daily dose                                      who are elderly, renally or hepatically impaired.
	 of 600 mg.
•	 For less severe pain: 50 mg or 100 mg 4 to 6 hourly.
                                                                                               Duration of treatment
Via parenteral administration                                                                  DOMADOL capsules and injections, should not be given
                                                                                               for longer than absolutely necessary.
Adults and children over the age of 14                                                         If the nature and severity of the disease require long-
years:                                                                                         term pain treatment with DOMADOL capsules or
•	 IV: 1 ampoule (100 mg - injected slowly or diluted in 	                                     injections, evaluation should be carried out initially and
	 solution for infusion and infused).                                                          at regular intervals to assess efficacy, adverse events
                                                                                               and the need for further treatment.
•	 IM: 1 ampoule (100 mg).
•	 SC: 1 ampoule (100 mg).
•	 Intravenous injection must be given slowly over
	 2 to 3 minutes.
•	 Maximum total daily dosage: 400 mg.
S5 DOMADOL 50 mg capsules. Reg. No.: 37/2.9/0596. Each capsule contains 50 mg tramadol.hydrochloride. Name and Address of the Holder of the
Certificate of Registration: Unichem SA (Pty) Ltd., Adrian Building 1st Floor, 32 Klinkenberg Street, Van Der Hoff Park, Potchefstroom 2531.
Marketed by: Activo Health (Pty) Ltd. Co. Reg. No.: 2009/009541/07. Block B, Arena Office Park, 272 West Avenue, Centurion, 0157, South Africa.
PO Box 11911, Zwartkop, 0051, South Africa. Tel: 0800 (ACTIVO) 228486 | Fax: 086 619 5833 | www.info@activo.co.za | www.activo.co.za