Name of Drug Classification Mechanism of Action Indication Contraindication Side Effects Nursing Responsibilities
Generic Name Pharmacologic Class: metabolized and utilized as -To provide a source of Contraindications: Sepsis, vein irritation, Before:
10% I.V. Fat Emulsion Parenteral Nutritional a source of energy causing calories and essential Disturbances of normal fat metabolism dyspnea, cyanosis, allergic Determine baseline values
Products an increase in heat fatty acids for patients (eg, pathologic hyperlipemia, lipoid reactions, hyperlipemia, for hemoglobin, platelet
Trade Name production, decrease in requiring parenteral nephrosis, acute pancreatitis if hypercoagulability, nausea, count, blood coagulation,
Intralipid 10% respiratory quotient and nutrition for extended accompanied by hyperlipidemia). vomiting, headache, liver function, plasma lipid
increase in oxygen periods of time (≥5 days). flushing, increase in profile.
Patient's Dose Therapeutic Class: consumption. Precautions: temperature, sweating,
100cc/hr Electrolyte Solutions -To provide a source of the patients capacity to eliminate the sleepiness, chest and back Repeat 1 or 2 times weekly
Pharmacokinetics: essential fatty acids for infused fat from the circulation must be pain, dizziness, liver during therapy in adults.
Contents -Intralipid is eliminated prevention of essential monitored by use of an appropriate dysfunction, blood Report significant deviations
Lipid content 0.2g/mL from the circulation via a fatty acid deficiency laboratory determination of serum dyscrasias; aluminum promptly.
(refined soybean oil); pathway like that of (EFAD). triglycerides. Overdosage must be toxicity (esp. preterm
emulsion for IV infusion; endogenous chylomicrons. avoided infants, renal impairment). During:
contains aluminum. -The exogenous fat particle Patient's Indication: Use aseptic technique with
is taken up by the LDL For TPN Drug Interactions: IV tubing dressing changes,
10% soy bean oil, 1.2% receptors and primarily No known drug interactions and TPN solution.
egg phospholipids, 2.25% hydrolyzed in the
glycerin, and water peripheral circulation After:
which removes the Observe patient closely.
Maximum Dose triglycerides. Thus, a Acute reactions tend to
Not >500mL on first day transient triglyceride level occur within the first 2 ½ h
may be elevated after of therapy.
Minimum Dose Intralipid infusion.
0.5ml/min -The triglycerides are Report difficulty breathing,
hydrolyzed by lipoprotein nausea, vomiting, or
Availability lipase to fatty acids and headache to physician.
Emulsion (100mL, glycerol.
250mL, 500mL) -The free fatty acids are Instruct client to report
used by the muscle as an fever, chills, soreness and
Route immediate source of energy drainage at infusion site.
Intravenous or re-converted into
triglycerides and stored as a
fat in the subcutaneous
tissue
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Fat Emulsion): Uses, I.V. Fat Emulsion): Fat Emulsion): Uses, Fat Emulsion): Uses, Uses, Dosage, Side Effects, Interactions, Fat Emulsion): Uses, Emulsion): Uses, Dosage,
Dosage, Side Effects, Uses, Dosage, Side Dosage, Side Effects, Dosage, Side Effects, Warning. (2019, September 4). RxList. Dosage, Side Effects, Side Effects, Interactions,
Interactions, Warning. Effects, Interactions, Interactions, Warning. Interactions, Warning. https://www.rxlist.com/intralipid-20- Interactions, Warning. Warning. (2019, September
(2019, September 4). Warning. (2019, (2019, September 4). (2019, September 4). drug.htm#description (2019, September 4). 4). RxList.
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