12th Jan 2022 MSc I Year
Radiation biology Sessional 2 Maximum marks 100,
Answer all questions
Five marks each (key points and word limit 100 words)
1. What are requirements for radiography? Explain their role in study, give examples?
2. Where can we perform the radiotherapy, the effect can be shown graphically, what would be X
and Y axis?
3. List the radioisotopes that can be used for radioimaging?
4. You want to facilitate the survival post irradiation exposure, what will you do to assist?
5. List different mutations associated with colon cancer?
6. The cancer onset to metastasis could be explained on basis of hypothetical model, what are
steps proposed?
7. Define different classes of lethal damage ?
8. Differentiate the radiation induced cataract from the one caused by nonionising radiations?
10 marks each (key points word limit 500 words)
9. In terms of treatment of cancer cells we use the dose fractionation, and also we use heavy
radiations? What is the basis of selection?
10. The radioprotectors are interesting chemicals how do they work, How does WR2721 work? How
much time before irradiation should it be provided?
11. The radiosensetisers are essentially utilizing certain specific properties of the cancer cells. Can
you list them? How do they influence the radiation effect? How much time before irradiation
should it be provided with explanation?
12. Write a concise note on radiation carcinogenesis? List out different types of radiation induced
cancer?
13. What is dose response effect on different tissues? Graphically explain radiation hormesis? Why is
it different from LNT?
14. Graphically explain post irradiation oxygen effect? How is it used to treat cancer cells and why it
leads to higher killing of the normal cells?
