Which of the following dosage form avoids hepatic first pass metabolism?
A. Syrup & suspension
B. Oral tablet
C. Oral capsule
D. Sub-lingual tablet*
What would you call a drug which is converted to active form after metabolism?
A. Toxic drug
B. Pro drug*
C. Orphan drug
D. Safe drug
E. Potent drug
A 65 years old female comes to your clinic with all the sign and symptoms of anemia. She is diagnosed as
a case of megaloblastic anemia. You decide parenteral B12 therapy. Which of the following route of
administration is notorious for anaphylactic shock if B12 is given by this route?
A. Intramuscular
B. Subcutaneous
C. Intravenous*
D. Intrathecal
A 26 years old female with 35 weeks of pregnancy was admitted in the Gynae/Obs unit. Her
investigation revealed Hb 7.5%. The Gynecologist advised parenteral iron therapy to make up the
deficiency of Hb.
Which of the following is the most commonly used iron preparation given intravenously?
A. Iron dextran*
B. Iron maltose
C. Iron sucrose
D. Ferrous gluconate
Forty years old male patient, a diagnosed case of CA small intestine, had hemoglobin of 9.2 gm/dl. He
was started on oral iron therapy. After few days, patient complained of some GIT upset (on and off
nausea, vomiting & diarrhea). Which one of the following oral iron preparation was responsible for his
problem?
A. Iron dextran
B. Sodium ferric gluconate
C. Iron sucrose
D. Ferrous sulfate*
A mother brought her two years child to emergency in panic, stating that her chocolate flavored iron
pills were taken by her son. Toxicity associated with acute iron poisoning usually includes which of the
following?
A. Dizziness, hypertension, and cerebral hemorrhage
B. Hyperthermia, delirium and coma
C. Hypotension, cardiac arrhythmias and seizures
D. Necrotizing gastroenteritis, shock and metabolic acidosis*
E. Severe hepatic injury, encephalitis and coma
A 34 years old woman has macrocytic anemia, an increased serum concentration of transferrin, and a
normal serum concentration of vitamin B12.The most likely cause of her anemia is deficiency of which of
the following?
A. Cobalamin
B. Erythropoietin
C. Folic acid*
D. Intrinsic factor
E. Iron
A 55 years old patient of chronic renal failure presented with severe anemia with Hb - 5gm/dl. Which of
the following is specific for production of RBCs in this case?
A. Erythropoietin*
B. Romiplostim
C. Granulocyte Stimulating factor
D. Interleukin-11 (eleven)
E. Granulocyte macrophage CSF
A physician sent an e-mail to the hospital pharmacist to know about the available iron preparations. In
reply, the pharmacist enlisted the following drugs. The physician wants to prescribe only oral medicine.
Which one of the following was selected by the physician?
A. Iron dextran
B. Sodium ferric gluconate
C. Iron sucrose
D. Ferrous gluconate*
Cinchonism (nausea, dizziness, headache, tinnitus, blurring of vision) is a side effect produced by which
of the following drug?
A. Primaquine
B. Artemether
C. Quinine*
D. Doxycycline
First chemotherapy session of an old man with CA lungs has been scheduled. Which one of the following
drugs is a drug of choice to relieve post chemotherapy vomiting?
A. dexamethasone
B. hyosine
C. lorazepam
D. metochlopramide
E. ondansetrone*
A FCPS part-2 trainee of medicine is coming across many patients with complaints of constipation. He
has to prescribe some laxative. Which one of the given conditions is an indication for the use of
laxatives?
A. dehydration
B. hepatic encephalopathy*
C. intestinal obstruction
D. undiagnosed abdominal pain
Adsorbents are known to be a safer drug in diarrhea. Which of the following side effect can still be
experienced by the patient?
A. blackening of stools
B. constipation*
C. intesusseption
D. paralytic illeus
E. respiratory depression
A 20 years old female came with complaints of repeated bowel movements, straining at stools, feeling
of incomplete evacuation, passing mucus and abdominal bloating and swelling. She is diagnosed as a
case of irritable bowel syndrome. Which one of the following drugs is the most appropriate for this
young female?
A. alosetron*
B. amitryptaline
C. citalopram
D. cilansetron
E. hyoscyamine
A 45 years old male had a heart transplant and is being maintained on immunosuppressant therapy. He
develops candida infection and is treated with Ketoconazole. What is the most common adverse effect
associated with this drug?
A. Cardiotoxicity
B. Visual disturbance
C. Inhibition of CYP450*
D. Nephrotoxicity
E. Infusion reaction
A middle aged woman was prescribed some medicine for her Gouty arthritis. After taking first dose she
experienced troublesome diarrhea and severe abdominal cramping. Which one of the following was
responsible for this condition?
A. Allopurinol
B. Colchicine*
C. Indomethacin
D. Sulfinpyrazone
E. Aspirin
A multigravida, 40 years old female reported to rural health center with severe backache and difficulty in
walking. All baseline investigations were found normal except vitamin D3 level which was less than 20
ng/mL. Medical officer should decide to start therapy with which form of vitamin D preparation?
A. Calcitriol*
B. Calcipotriene
C. Doxercalciferol
D. Paricalcitol
