Effects of Music As An Adjunctive Therapy On Severity of Symptoms in Patients With Obsessive-Compulsive Disorder: Randomized Controlled Trial
Effects of Music As An Adjunctive Therapy On Severity of Symptoms in Patients With Obsessive-Compulsive Disorder: Randomized Controlled Trial
Deldar Morad Abdulah, Salim Saadi Miho Alhakem & Rasoul Sabri Piro
To cite this article: Deldar Morad Abdulah, Salim Saadi Miho Alhakem & Rasoul Sabri Piro
(2018): Effects of music as an adjunctive therapy on severity of symptoms in patients with
obsessive-compulsive disorder: Randomized controlled trial, Nordic Journal of Music Therapy, DOI:
10.1080/08098131.2018.1546222
Article views: 41
ABSTRACT
Introduction: Obsessive-compulsive disorder is a critical mental disorder. Music
listening is non-invasive, safe and harmless, well-tolerated, inexpensive, and has
therapeutic advantages in a wide range of mental disorders. The impact of passive
music listening as an adjunctive therapy on symptoms severity in patients with
obsessive-compulsive disorder was evaluated in this study.
Methods: In a parallel posttest-study only randomized controlled trial, 36 patients
(range 19 to 65 years) were randomly allocated to experimental group (n = 17) or
control group (n = 19) in Duhok, Iraq in 2017. The experimental group received
seven 50-minute relaxing music tracks to listen daily in addition to regular pharma-
cological treatment for a three-month period. The control group received regular
treatment only. The severities of obsession, compulsion, and obsessive-compulsive
symptoms were assessed using the Yale-Brown Obsessive Compulsive Scale symp-
tom severity scale following study completion only.
Results: The experimental group had significantly lower symptom severities than the
control group in terms of obsessions and compulsions, and the overall obsessive-
compulsive score, effect size: 0.77, 0.95, and 0.78,, and 95% CI: 6.29–9.43; CI: 6.22–
9.43; and CI: 12.57–18.81, respectively.
Discussion: The study showed that passive music listening as an adjunctive therapy
to regular treatment is an effective method to reduce obsessions and compulsions
severities in patients with obsessive-compulsive disorder. Clinical Trial Registration
Number in the local registry: 21082016–6 (21 August 2016).
Introduction
Music is used in everyday life for a variety of purposes such as entertainment and is used
for its therapeutic benefits in public health settings and in treatment of a wide range of
mental disorders. Impacts of music therapy (MT) have been recognized owing to its
relaxing characteristics. According to one definition, MT is the “systematic use of music
Methods
Study design and recruitment of participants
All 324 patients who visited a psychiatrist’s private clinic (clinic of the first author) in
Duhok, Iraq between 15 October 2016 and 20 November 2016 were screened clinically
by the psychiatrist (first author) for eligibility criteria of the study (Figure 1). The baseline
information of those patients who met eligibility criteria including age, gender, and
education level were recorded in a pre-designed questionnaire. The diagnosis was
Figure 1. Flow of participants through the study (according to intention to treat approach).
4 D. M. ABDULAH ET AL.
established according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth
Edition (DSM-5) (American Psychiatric Association, 2013).
The psychiatrist recorded the information of those patients diagnosed with any
types of OCD in a pre-designed questionnaire. The patients’ names were coded
consecutively and entered into an SPSS file. The participants were randomly assigned
into two groups through generating a list of simple random numbers by a computer.
Hereafter, the objectives of the study were explained to patients in experimental
group and required information to the control group and they were invited by the
psychiatrist to participate in the study following random assignment.
The patients in experimental group received the music listening passively in
addition to regular pharmacotherapy for a three-month period. The patients allocated
to the control group received only prescribed medications by the study psychiatrist
for the same period. The obsession and compulsion symptoms of both groups were
measured by the psychiatrist following the study completion only.
using GPower 3.1.9 statistical software, and aimed to recruit as many patients as
possible to maximize test power.
intervention to reduce the possible bias of music listening by this group, they were just
informed of their future symptoms severity measurement for a study.
Measurement instrument
The severity of obsessions, compulsions, and obsessive-compulsive symptoms in both
experimental and control groups were assessed using the English version of the Yale-
Brown Obsessive Compulsive Scale (YBOCS) following study completion (Baer &
Blais, 2010). The YBOCS symptom severity scale was administered and assessed
independently by the senior psychiatrist only. It is a 10-item scale to rate the severity
of obsessions and compulsions, each item with a five-point scale ranging from 0 (no
symptoms) to 4 (extremely severe symptoms). Anchors are given for each response
category, for example a rating of 1 on time occupied by obsessive thoughts indicates
“mild, less than 1 hr/day or occasional intrusions”. The total score of the scale is
between 0 and 40 (Baer & Blais, 2010). For the subscales of obsession and compul-
sion, the respective items are added together to obtain a final score ranging from zero
(no symptoms) to 20 (extremely severe symptoms). The obsessions items covered by
YBOCS are time occupied by obsessive thoughts, interference due to obsessive
thoughts, distress associated with obsessive thoughts, resistance against obsessions,
degree of control over obsessive thoughts. Compulsions items are time spent per-
forming compulsive behaviors, interference due to compulsive behaviors, distress
associated with compulsive behavior, resistance against compulsions, degree of con-
trol over compulsive behavior.
Statistical analysis
The descriptive statistics of the study included frequency (percentage) for gender and
education, and mean (SD) for age. At baseline, the homogeneity of two groups of the
study was confirmed through the independent t-test, chi-squared or Fisher’s exact
test. The symptoms severities of OCD in both arms were measured by mean and
standard deviation. The effects of intervention (music and medication together)
versus control (medication only) on the severity of obsessions, compulsions, and
obsessive-compulsive symptoms were examined through independent t-tests in both
intention-to-treat and per-protocol analyses. The null hypothesis was rejected in
a p-value of less than 0.05. The Statistical Package for Social Sciences version 23
(SPSS 23 IBM) was used for statistical analysis and effect size of music listening on
symptoms severity (Cohen’s d) was calculated by GPower 3.1.9. The individual
participant data are available online as supplementary material to promote transpar-
ency and replicability.
Ethical considerations
The confidentiality of personal information was guaranteed to the patients in both
groups and their oral and written consents with consent forms were taken prior to
study implementation. The approval of the protocol of the study was obtained from
the Scientific Research Division, Directorate of Planning, Duhok Directorate General
of Health, Ministry of Health, Kurdistan Regional Government Iraq (Clinical Trial
Registration Number: 21082016–6 in 21 August 2016) and the intervention was
NORDIC JOURNAL OF MUSIC THERAPY 7
conducted in accordance with the Declaration of Helsinki. The music was not
expected to cause any harm to patients.
Results
Baseline characteristics of patients in the experimental and control trial arms are
depicted in Table 1a. The mean age of patients (57 persons) was 29.41
(SD = 7.85 years (range 19 to 65). More than half of the patients were male (30/57,
52.6%). The male:female ratio was 1.11. The patients in experimental and control
groups were comparable in education level (p = .280, see Table 1a). Similarly, the
mean age of patients who were followed up (36 patients) was 30.66 (SD = 8.85) years
compared to 27.33 (SD = 5.38) years in those who dropped out (21 patients;
p = .086). In addition, the followed-up and dropped-out patients were comparable
in gender and education level (p = .284 and p = .947, respectively, see Table 1b).
The intention-to-treat analysis suggested that the obsessive-compulsive symptoms,
obsessions and compulsions were significantly lower in patients randomized to
Table 2. Comparison of obsessions and compulsions between intervention (music and medication) and control
(medication only).
a. Intention-to-treat approach (interventions as randomized).
Mean (SD)
Randomized to Randomized to
Patients’ control intervention p-value Effect size
Characteristics(n = 36) (n = 18) (n = 18) (two-sided) (Cohen’s d)
Obsession Severity 1 9.50 (4.69) 6.17 (3.73) 0.025 0.78
Compulsion Severity 1 10.17 (4.94) 5.89 (3.53) 0.005 0.99
OCD Severity 1 (YBOCS Scale) 18.83 (9.71) 12.06 (7.13) 0.023 0.79
1
independent t-test was performed for statistical calculations.
*The present table was performed as one patient was shifted from experimental to the control arm owing to non-adherence to
the music listening.
Table 3. The severity of obsession thoughts and compulsions behaviours in control and intervention groups.
a. Intention-to-treat approach
Mean (SD)
Randomized
Randomized to
to Control Intervention p-value Effect size
Obsession and Compulsions (YBOCS Scale) (n = 18) (n = 18) (two-sided) (Cohen’s d)
Obsessions
Time occupied by obsessive thoughts 1.67 (.97) 1.11 (1.02) 0.104 0.56
Interference due to obsessive thoughts 1.83 (1.30) 1.11 (.83) 0.056 0.66
Distress associated with obsessive thoughts 2.00 (1.14) 1.17 (.92) 0.022 0.80
Resistance against obsessions 1.89 (1.32) 1.11 (.90) 0.048 0.68
Degree of control over obsessive thoughts 2.11 (1.23) 1.67 (1.14) 0.269 0.37
Compulsions
Time spent performing compulsive behaviors 1.78 (1.06) 1.00 (.77) .017 0.84
Interference due to compulsive behaviors 1.89 (1.08) .94 (.80) .006 1.00
Distress associated with compulsive behavior 2.06 (.97) 1.33 (.77) .020 0.84
Resistance against compulsions 2.11 (1.18) 1.39 (1.29) .089 0.58
Degree of control over compulsive behavior 2.06 (1.11) 1.22 (.88) .018 0.84
Independent t-test was performed for all statistical analysis.
The bold numbers show the significant differences.
Discussion
The present study showed that overall obsessive-compulsive symptoms and obses-
sions and compulsions were significantly lower in a group following adjunctive
therapy with music listening compared to those receiving standard care alone. In
10 D. M. ABDULAH ET AL.
addition, the patients who received the adjunctive therapy had a substantially lower
compulsion severity than those who received standard care only.
A growing body of literature has paid their attention to the impact of music listening
on different psychiatric disorders, however there is a dearth of research on the impact of
passive or active music listening on symptoms severity in patients with OCD. Prior to
this study, the study by Bidabadi and Mehryar (2015) was the only one available on the
effects of receptive music listening. They assigned 30 patients randomly to an interven-
tion group (pharmacotherapy and cognitive-behavior therapy) with 12 sessions of
individual music treatment (n = 15) or a control group with regular treatment only
(n = 15). The symptoms severities were assessed baseline and after one month. The study
revealed that the obsession score was reduced from 15.1 (SD = 1.7) in the control group
to 12.4 (SD = 1.9) (p < 0.001) with effect size = 56.7% (partial eta squared) With respect to
OCD subtypes, substantial differences were seen for checking (p < 0.004) and slowness
(p < 0.019), but not for washing or responsibility.
Their study focused on the impact of receptive music listening on sub-type
obsessions in patients with OCD plus depression and anxiety comorbidities through
the Maudsley obsessive–compulsive inventory (MOCI), which has limited reliability
(Chan, 1990; Grabill et al., 2008). In contrast, overall obsessive-compulsive symptoms
and obsessions and compulsions and their content were scrutinized in detail in the
present study through the Yale-Brown Obsessive Compulsive Scale, a clinical assess-
ment considered gold standard (Grabill et al., 2008). This study showed that overall
symptoms, obsessions and compulsions were significantly lower in patients who
underwent receptive music listening compared to those in regular treatment only.
Despite overall improvement in patients who received music listening, their degree of
control over some obsessive thoughts was not sufficient, whereas their overall control
over compulsive behaviors reached a significant level. Making a between-study
comparison is hard owing to using two diverse types of intervention, as we did not
use cognitive-behavior therapy for our patients in the experimental group. However,
both studies found a significant decrease in overall obsessive thoughts of the OCD
patients. It is unclear whether the time period selected in this study (three months) is
associated with a greater decrease in symptoms severity compared to one month as
applied by Bidabadi and Mehryar (2015).
It is significant to return OCD patients to their normal social environment. In this
regard, music therapy or listening activities could be used as a form of social
communication to enhance the interaction between people through cooperation
and integration of patients with other society members (Schulkin & Raglan, 2014;
Yang, Li, Weng, & Zhang, 1998), as the disorder is responsible for the significant
emotional distress and difficulties with a sound relationship with others (Fundukian
& Wilson, 2008).
The impact of music listening on symptom severity in OCD patients may refer to its
capacity to evoke positive or proper memories, which may lead to a new way of
cognitive recuperation and create controlled circumstances for a developing new
perspectives (Yang et al., 1998). Music listening can promote the exploration of
memories associated with life issues and facilitation of cognitive changes and alteration
of irrational thoughts. The positive changes in cognitive aspects could assist the person
to manage these kinds of thoughts or compulsions (Gutiérrez & Camarena, 2015). In
congruence with this phenomenon, the current study showed that the patients who
received music listening applied significantly less resistance (more control) against
NORDIC JOURNAL OF MUSIC THERAPY 11
these obsessive thoughts and experienced less distress than those who received stan-
dard care only. However, it seems that music listening is not sufficient for a patient to
achieve complete control on these kinds of obsessive thoughts.
In effectiveness of alternative medicine as adjunct therapy for psychiatric disor-
ders, their scientific classification must be taken into consideration. Obsessive-
compulsive disorder was moved to a new category in 2013 in the fifth version of
Diagnostic and Statistical Manual of Mental Disorders (DSM-5) (American
Psychiatric Association, 2013). It is now entitled as “obsessive-compulsive and related
disorders”, while it was in the “anxiety disorders” category in the previous version
(DSM-IV) (First, 2000). In the current study, the diagnosis of an OCD was estab-
lished according to the DSM-5 (American Psychiatric Association, 2013).
The overall effect of music listening in anxiety disorders may relate to the role of
music listening as a relaxation technique and its additional capacity in worry reduc-
tion, a negative kind of preservative thought (Spaeth, 2015) reflecting a common
feature in all anxiety disorders (Barlow, Raffa, & Cohen, 2002). We cannot present
the effect of music listening on worry in our sample size due to lack of worry
measurement in this study.
The obsessive thoughts in OCD patients are different from worries, as obsessive
thoughts do not reflect real-life issues. However, a compulsive behavior is performed
by an OCD patient in response to an obsessive thought to lower the level of anxiety
created by the obsession(s) in spite of the patient’s attempts to suppress the worri-
some images and thoughts (Fundukian & Wilson, 2008). In addition, worry is
responsible for creation and maintenance of negative affective and physiological
experiences (Newman, Llera, Erickson, Przeworski, & Castonguay, 2013). OCD is
not classified as an anxiety disorder, but a combination of neurobiological, environ-
mental, hereditary, and psychological factors have a role in this disorder (American
Psychiatric Association, 2013).
The other possible impact of music listening on OCD patients may relate to fear
reduction, as the compulsion among the patients is triggered through the direct
contact with the feared thought or object stirring up intense anxiety and a forceful
provocation or incitement to compulsion engagement (Fundukian & Wilson, 2008).
We strongly make the hypothesis that music listening assists the patients to combat
worry and promote the positive affect in his/her thoughts resulting in more control
on compulsions.
To understand the impact of various kinds of music, it is recommended to
determine the type of music according to audiences’ preference using standardized
scales such as the Scale for Evaluating Music for Health Promotion (SEMHP)
(Yoshida, Kobayashi, Sapkota, & Akkhavong, 2013). This scale has a good estimation
of the reliability and validity of content. Future studies can take their concentration
on impact of music listening on distinct OCD types or compare active and receptive
music therapies.
confirmed that different types of music have different affective and physiological
responses (Spaeth, 2015).
Disclosure statement
No potential conflict of interests were reported by the author.
Notes on contributors
Deldar Morad Abdulah, Master in Public Health from La Trobe University, Australia and B.Sc in
Occupational Health from Iran University of Medical Sciences. Assistant Lecturer at the Adult
Nursing Department, College of Nursing, University of Duhok, Iraqi Kurdistan.
Salim Saadi Miho Alhakem, M.B.Ch.B. F.I.C.M.S (PSYCH)(M.D). Lecturer, Senior Psychiatrist,
Medicine Department, College of Medicine, University of Duhok, Iraqi Kurdistan.
Rasoul Sabri Piro, Master in Mental Health and Psychiatric Nursing from Hawler Medical
University-Iraq) and B.Sc in Nursing from Iran University of Medical Sciences-Iran. Lecturer and
Head of Adult Nursing Department, College of Nursing, University of Duhok, Iraqi Kurdistan.
ORCID
Deldar Morad Abdulah http://orcid.org/0000-0002-8986-5793
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