SAFETY DATA SHEET Page: 1 of 6
Chlorpyrifos Revision: 03/18/2017
according to Regulation (EC) No. 1907/2006 as amended by (EC) No. 1272/2008
Section 1. Identification of the Substance/Mixture and of the Company/Undertaking
1.1 Product Code: 21412
Product Name: Chlorpyrifos
Synonyms: phosphorothioic acid O,O-diethyl O-(3,5,6-trichloro-2-pyridinyl) ester;
1.2 Relevant identified uses of the substance or mixture and uses advised against:
Relevant identified uses: For research use only, not for human or veterinary use.
1.3 Details of the Supplier of the Safety Data Sheet:
Company Name: Cayman Chemical Company
1180 E. Ellsworth Rd.
Ann Arbor, MI 48108
Web site address: www.caymanchem.com
Information: Cayman Chemical Company +1 (734)971-3335
1.4 Emergency telephone number:
Emergency Contact: CHEMTREC Within USA and Canada: +1 (800)424-9300
CHEMTREC Outside USA and Canada: +1 (703)527-3887
Section 2. Hazards Identification
2.1 Classification of the Substance or Mixture:
Acute Toxicity: Oral, Category 3
Aquatic Toxicity (Acute), Category 1
Aquatic Toxicity (Chronic), Category 1
2.2 Label Elements:
GHS Signal Word: Danger
GHS Hazard Phrases:
H301: Toxic if swallowed.
H400: Very toxic to aquatic life.
H410: Very toxic to aquatic life with long lasting effects.
GHS Precaution Phrases:
P264: Wash {hands} thoroughly after handling.
P273: Avoid release to the environment.
GHS Response Phrases:
P301+310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P330: Rinse mouth.
P391: Collect spillage.
GHS Storage and Disposal Phrases:
Please refer to Section 7 for Storage and Section 13 for Disposal information.
Multi-region format
SAFETY DATA SHEET Page: 2 of 6
Chlorpyrifos Revision: 03/18/2017
2.3 Adverse Human Health Material may be irritating to the mucous membranes and upper respiratory tract.
Effects and Symptoms: May be harmful by inhalation or skin absorption.
May cause eye, skin, or respiratory system irritation.
Toxic if swallowed.
Very toxic to aquatic life with long lasting effects.
To the best of our knowledge, the toxicological properties have not been thoroughly investigated.
Section 3. Composition/Information on Ingredients
CAS # / Hazardous Components (Chemical Name)/ Concentration EC No./ GHS Classification
RTECS # REACH Registration No. EC Index No.
2921-88-2 Chlorpyrifos 100.0 % 220-864-4 Acute Tox.(O) 3: H301
TF6300000 015-084-00-4 Aquatic (A) 1: H400
Aquatic (C) 1: H410
Section 4. First Aid Measures
4.1 Description of First Aid
Measures:
In Case of Inhalation: Remove to fresh air. If not breathing, give artificial respiration or give oxygen by trained personnel.
Get immediate medical attention.
In Case of Skin Contact: Immediately wash skin with soap and plenty of water for at least 15 minutes. Remove contaminated
clothing. Get medical attention if symptoms occur. Wash clothing before reuse.
In Case of Eye Contact: Hold eyelids apart and flush eyes with plenty of water for at least 15 minutes. Have eyes examined
and tested by medical personnel.
In Case of Ingestion: Wash out mouth with water provided person is conscious. Never give anything by mouth to an
unconscious person. Get medical attention. Do NOT induce vomiting unless directed to do so by
medical personnel.
Section 5. Fire Fighting Measures
5.1 Suitable Extinguishing Use alcohol-resistant foam, carbon dioxide, water, or dry chemical spray.
Media: Use water spray to cool fire-exposed containers.
Unsuitable Extinguishing A solid water stream may be inefficient.
Media:
5.2 Flammable Properties andNo data available.
Hazards:
No data available.
Flash Pt: No data.
Explosive Limits: LEL: No data. UEL: No data.
Autoignition Pt: No data.
5.3 Fire Fighting Instructions: As in any fire, wear self-contained breathing apparatus pressure-demand (NIOSH approved or
equivalent), and full protective gear to prevent contact with skin and eyes.
Multi-region format
SAFETY DATA SHEET Page: 3 of 6
Chlorpyrifos Revision: 03/18/2017
Section 6. Accidental Release Measures
6.1 Protective Precautions, Avoid raising and breathing dust, and provide adequate ventilation.
Protective Equipment and As conditions warrant, wear a NIOSH approved self-contained breathing apparatus, or respirator,
Emergency Procedures: and appropriate personal protection (rubber boots, safety goggles, and heavy rubber gloves).
6.2 Environmental Take steps to avoid release into the environment, if safe to do so.
Precautions:
6.3 Methods and Material For Contain spill and collect, as appropriate.
Containment and Cleaning Transfer to a chemical waste container for disposal in accordance with local regulations.
Up:
Section 7. Handling and Storage
7.1 Precautions To Be Taken Avoid breathing dust/fume/gas/mist/vapours/spray.
in Handling: Avoid prolonged or repeated exposure.
7.2 Precautions To Be Taken Keep container tightly closed.
in Storing: Store in accordance with information listed on the product insert.
Section 8. Exposure Controls/Personal Protection
8.1 Exposure Parameters:
CAS # Chemical Name Jurisdiction Recommended Exposure Limits Notations
2921-88-2 Chlorpyrifos ACGIH TLV TLV: 0.1 mg/m3 (Inhalation)
France VL TWA: 0.2 mg/m3
Britain EH40 TWA: 0.2 mg/m3 ()
STEL: 0.6 mg/m3 ()
8.2 Exposure Controls:
8.2.1 Engineering Controls Use process enclosures, local exhaust ventilation, or other engineering controls to control airborne
(Ventilation etc.): levels below recommended exposure limits.
8.2.2 Personal protection equipment:
Eye Protection: Safety glasses
Protective Gloves: Compatible chemical-resistant gloves
Other Protective Clothing: Lab coat
Respiratory Equipment NIOSH approved respirator, as conditions warrant.
(Specify Type):
Work/Hygienic/Maintenan Do not take internally.
ce Practices: Facilities storing or utilizing this material should be equipped with an eyewash and a safety shower.
Wash thoroughly after handling.
No data available.
Multi-region format
SAFETY DATA SHEET Page: 4 of 6
Chlorpyrifos Revision: 03/18/2017
Section 9. Physical and Chemical Properties
9.1 Information on Basic Physical and Chemical Properties
Physical States: [ ] Gas [ ] Liquid [ X ] Solid
Appearance and Odor: A crystalline solid
pH: No data.
Melting Point: No data.
Boiling Point: No data.
Flash Pt: No data.
Evaporation Rate: No data.
Flammability (solid, gas): No data available.
Explosive Limits: LEL: No data. UEL: No data.
Vapor Pressure (vs. Air or mm No data.
Hg):
Vapor Density (vs. Air = 1): No data.
Specific Gravity (Water = 1): No data.
Solubility in Water: No data.
Solubility Notes: Soluble in: MeOH; EtOH; chloroform; ethyl acetate;
Octanol/Water Partition No data.
Coefficient:
Autoignition Pt: No data.
Decomposition Temperature: No data.
Viscosity: No data.
9.2 Other Information
Percent Volatile: No data.
Molecular Formula & Weight: C9H11Cl3NO3PS 350.6
Section 10. Stability and Reactivity
10.1 Reactivity: No data available.
10.2 Stability: Unstable [ ] Stable [ X ]
10.3 Stability Note(s): Stable if stored in accordance with information listed on the product insert.
Polymerization: Will occur [ ] Will not occur [ X ]
10.4 Conditions To Avoid: No data available.
10.5 Incompatibility - Materials amines
To Avoid: brass
copper
copper alloys
strong acids and
strong bases
strong oxidizing agents
10.6 Hazardous carbon dioxide
Decomposition or carbon monoxide
Byproducts: hydrogen chloride gas
nitrogen oxides
phosphorous oxides
Multi-region format
SAFETY DATA SHEET Page: 5 of 6
Chlorpyrifos Revision: 03/18/2017
Section 11. Toxicological Information
11.1 Information on The toxicological effects of this product have not been thoroughly studied.
Toxicological Effects: Chlorpyrifos - ToxicityvData: Oral TDLO (man): 300 mg/kg; Oral LD50 (rat): 82 mg/kg;
Intraperitoneal LD50 (mouse): 192 mg/kg;
Chronic Toxicological Chlorpyrifos - Investigated as a agricultural chemical, drug, hormone, mutagen, reproductive
Effects: effector.
Only select Registry of Toxic Effects of Chemical Substances (RTECS) data is presented here.
See actual entry in RTECS for complete information.
Chlorpyrifos RTECS Number: TF6300000
CAS # Hazardous Components (Chemical Name) NTP IARC ACGIH OSHA
2921-88-2 Chlorpyrifos n.a. n.a. A4 n.a.
Section 12. Ecological Information
12.1 Toxicity: Avoid release into the environment.
Runoff from fire control or dilution water may cause pollution.
12.2 Persistence and No data available.
Degradability:
12.3 Bioaccumulative No data available.
Potential:
12.4 Mobility in Soil: No data available.
12.5 Results of PBT and vPvB No data available.
assessment:
12.6 Other adverse effects: No data available.
Section 13. Disposal Considerations
13.1 Waste Disposal Method: Dispose in accordance with local, state, and federal regulations.
Section 14. Transport Information
14.1 LAND TRANSPORT (US DOT):
DOT Proper Shipping Name: Toxic solids, organic, n.o.s. (Chlorpyrifos)
DOT Hazard Class: 6.1 POISON
UN/NA Number: UN2811 Packing Group: III
14.1 LAND TRANSPORT (European ADR/RID):
ADR/RID Shipping Name: Toxic solids, organic, n.o.s. (Chlorpyrifos)
UN Number: 2811 Packing Group: III
Hazard Class: 6.1 - POISON
14.3 AIR TRANSPORT (ICAO/IATA):
ICAO/IATA Shipping Name: Toxic solids, organic, n.o.s. (Chlorpyrifos)
Additional Transport Transport in accordance with local, state, and federal regulations.
Information: When sold in quantities of less than or equal to 1 mL, or 1 g, with an Excepted Quantity Code of
E1, E2, E4, or E5, this item meets the De Minimis Quantities exemption, per IATA 2.6.10.
Therefore packaging does not have to be labeled as Dangerous Goods/Excepted Quantity.
Multi-region format
SAFETY DATA SHEET Page: 6 of 6
Chlorpyrifos Revision: 03/18/2017
Section 15. Regulatory Information
EPA SARA (Superfund Amendments and Reauthorization Act of 1986) Lists
CAS # Hazardous Components (Chemical Name) S. 302 (EHS) S. 304 RQ S. 313 (TRI)
2921-88-2 Chlorpyrifos No Yes 1 LB No
CAS # Hazardous Components (Chemical Name) Other US EPA or State Lists
2921-88-2 Chlorpyrifos CAA HAP,ODC: No; CWA NPDES: Yes; TSCA: No; CA
PROP.65: No
Regulatory Information This SDS was prepared in accordance with 29 CFR 1910.1200 and Regulation (EC)
Statement: No.1272/2008.
Section 16. Other Information
Revision Date: 03/18/2017
Additional Information About No data available.
This Product:
Company Policy or Disclaimer: DISCLAIMER: This information is believed to be accurate and represents the best information
currently available to us. However, we make no warranty of merchantability or any other warranty,
express or implied, with respect to such information, and we assume no liability resulting from its
use. Users should make their own investigations to determine the suitability of the information for
their particular purposes.
Multi-region format
