Pharmacology
Depressant- decreases; negative
Inhibition- stops the function of the cell or body
Replacement- replenish; replace
Nursing Pharmacology Irritation- causes undesirable effect to the body but unharmful;
ex: laxatives and ipeca
- Discusses what is the effect of the drug to the body and what
does the body do to the drug.
Pharmacology
- The study of how the drug works in the body, its side effects
and the way the body uses the drug.
Drug
- Has different uses and purpose in the body.
- Any substance used in:
Diagnosis- identifying diseases
Prevention- prevent diseases
Treatment- treat/ cure diseases
Pharmacokinetics
- K stands for “Katawan” or body
- What does your body do to the drug
4 steps: “ADME”
Absorption
- small intestine absorbs the diluted drug for the blood to carry it
throughout the body.
Has 2 terms:
First Pass Effect- the initial time needed by the body to absorb the drug
Bioavailability- total time needed by the small intestine to absorb the
drug; goes with the blood to circulate around the body.
Distribution
- the blood distributes the diluted drug throughout the body
Metabolism
- liver is responsible for metabolism
- Half Life- partial time needed by the drug to have its effects; if
the drugs life is written in the box by 6 hours you should
multiply it in 2 to administer the drug again.
Excretion- kidney eliminates the waste product
Pharmacodynamics
- D stands for “Drugs”
- What does the drug do to the body
Has 3 steps: “OPD”
Onset- initial effect of the drug to the body
Peak- maximum effect of the drug to the body
Duration- total effect of the drug to the body
Maintaining the balance of Homeostasis
Agonist- positive effect; increases
Antagonist- negative effect; decreases
Nonselective- can bind with any types of receptors
Nonspecific- anywhere in your body
Pharmacogenetics
- being used to learn ahead of time what the best drug or the best
dose of a drug will be for a person
5 steps: “LSATD”
Loading Dose- Initial dose or first dose
Side Effects- expected effects of the drug; mild condition
Adverse Effects- unexpected effect of the drug; severe
condition
Toxic Effect- harmful effect to the body
Drug Tolerance- amount of the drug needed by the body to
produce an effect.
Therapeutic Index- safe level of the drug
Placebo Effect- unethical; unprofessional; preconditions the mind of the
patient to produce the physiological effect
Categories of Drug Action
Stimulation- increases; positive